chr22 : 33,850,777 – 33,851,374
597 bp 87 TFs 1 linked gene
This 597 bp open chromatin element is linked to LARGE1 and is bound by 87 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
LARGE1 71.7 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr22:33,845,777 – 33,856,374
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
87 transcription factors
Source
Cell type
AR 2 datasets
ChIP LNCaP-abl GSE39459.AR.LNCaP-abl 117 bp overlap
ChIP prostate-cancer_PDX_81 GSE130408.AR.prostate-cancer_PDX_81 74 bp overlap
ARID1A 3 datasets
ChIP MCF-7_4-hydroxytamoxifen GSE123284.ARID1A.MCF-7_4-hydroxytamoxifen 239 bp overlap
ChIP MCF-7_Fulvestrant GSE123284.ARID1A.MCF-7_Fulvestrant 106 bp overlap
ChIP MCF-7_JQ1 GSE123284.ARID1A.MCF-7_JQ1 287 bp overlap
ARNT 1 dataset
ChIP SK-MEL-28 GSE85352.ARNT.SK-MEL-28 145 bp overlap
ASH2L 1 dataset
ChIP WA01 ENCSR850KIP.ASH2L.WA01 597 bp overlap
BACH2 1 dataset
ChIP OCI-Ly7 GSE44420.BACH2.OCI-Ly7 114 bp overlap
BAF155 1 dataset
ChIP VCaP_shARID1A GSE110655.BAF155.VCaP_shARID1A 52 bp overlap
BCL11A 2 datasets
ChIP H1 ENCFF833IPY 145 bp overlap
ChIP WA01 ENCSR000BIP.BCL11A.WA01 161 bp overlap
BCL6 3 datasets
ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 102 bp overlap
ChIP OCI-Ly7 GSE44420.BCL6.OCI-Ly7 129 bp overlap
ChIP SU-DHL-4 GSE119038.BCL6.SU-DHL-4 222 bp overlap
BMI1 1 dataset
ChIP MCF-7 ENCSR966YYJ.BMI1.MCF-7 292 bp overlap
BRD4 3 datasets
ChIP MCF-7_parental GSE123284.BRD4.MCF-7_parental 334 bp overlap
ChIP MCF-7_parental GSE123284.BRD4.MCF-7_parental 183 bp overlap
ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 52 bp overlap
CHD1 2 datasets
ChIP WA01 ENCSR000AQK.CHD1.WA01 118 bp overlap
ChIP WA01 ENCSR000AQK.CHD1.WA01 239 bp overlap
CHD7 1 dataset
ChIP WA01 ENCSR000AVA.CHD7.WA01 132 bp overlap
COMMD3-BMI1,BMI1 1 dataset
ChIP MCF-7 ENCFF570JPP 365 bp overlap
CREB1 1 dataset
ChIP LNCaP-abl_SHCTR GSE63034.CREB1.LNCaP-abl_SHCTR 243 bp overlap
CTBP2 1 dataset
ChIP MCF-7 GSE107013.CTBP2.MCF-7 111 bp overlap
ELF3 3 datasets
ChIP PDAC GSE64557.ELF3.PDAC 216 bp overlap
ChIP PDAC_KOKLF5 GSE64557.ELF3.PDAC_KOKLF5 203 bp overlap
ChIP PDAC_SHCTR GSE64557.ELF3.PDAC_SHCTR 236 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 341 bp overlap
EP300 2 datasets
ChIP H1 ENCFF927IYK 290 bp overlap
ChIP WA01 ENCSR000BKK.EP300.WA01 278 bp overlap
ERG 1 dataset
ChIP VCaP GSE49091.ERG.VCaP 121 bp overlap
ESR1 3 datasets
ChIP breast_tumor_Male_10 GSE104399.ESR1.breast_tumor_Male_10 61 bp overlap
ChIP endometrioid-adenocarcinoma_tumor_2 GSE94031.ESR1.endometrioid-adenocarcinoma_tumor_2 53 bp overlap
ChIP primary-endometrium-cancer_E1_DSG GSE114737.ESR1.primary-endometrium-cancer_E1_DSG 90 bp overlap
ETS1 1 dataset
ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 224 bp overlap
ETV2::DRGX 1 dataset
Motif ES_0h ES_0h-ETV2DRGX_MA1940.2 12 bp overlap
FOS 3 datasets
ChIP CFPAC-1 GSE119930.FOS.CFPAC-1 130 bp overlap
ChIP MCF-7 ENCFF282FWZ 146 bp overlap
ChIP MCF-7 ENCSR569XNP.FOS.MCF-7 83 bp overlap
FOXA1 5 datasets
ChIP CFPAC-1 GSE119930.FOXA1.CFPAC-1 64 bp overlap
ChIP CFPAC-1_FOXA2-KO GSE119930.FOXA1.CFPAC-1_FOXA2-KO 112 bp overlap
ChIP PDAC GSE64557.FOXA1.PDAC 169 bp overlap
ChIP PDAC_KOKLF5 GSE64557.FOXA1.PDAC_KOKLF5 184 bp overlap
ChIP PDAC_SHCTR GSE64557.FOXA1.PDAC_SHCTR 268 bp overlap
FOXA2 5 datasets
ChIP BJ1-hTERT_CDT1 GSE92491.FOXA2.BJ1-hTERT_CDT1 69 bp overlap
ChIP CFPAC-1 GSE119930.FOXA2.CFPAC-1 128 bp overlap
ChIP CFPAC-1_EV GSE119930.FOXA2.CFPAC-1_EV 94 bp overlap
ChIP DE DE-FOXA2-1 350 bp overlap
ChIP DE DE-FOXA2-2 360 bp overlap
GATA3_Nter 1 dataset
ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 205 bp overlap
GATA4 3 datasets
ChIP DE DE-GATA4-1 430 bp overlap
ChIP DE DE-GATA4-2 544 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 368 bp overlap
GATA6 10 datasets
ChIP DE DE-GATA6-1 417 bp overlap
ChIP DE DE-GATA6-2 460 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 597 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 563 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 388 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 491 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 597 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 522 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 471 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 276 bp overlap
GRHL1 2 datasets
ChIP MCF-7 GSE140185.GRHL1.MCF-7 403 bp overlap
ChIP MCF-7_ARID1A-KO GSE140185.GRHL1.MCF-7_ARID1A-KO 131 bp overlap
GRHL2 4 datasets
ChIP MCF-7 GSE109820.GRHL2.MCF-7 263 bp overlap
ChIP MCF-7 GSE99680.GRHL2.MCF-7 159 bp overlap
ChIP MCF-7-WS8_VEH GSE113092.GRHL2.MCF-7-WS8_VEH 323 bp overlap
ChIP MCF-7_E2_45min GSE109820.GRHL2.MCF-7_E2_45min 310 bp overlap
HDAC2 2 datasets
ChIP H1 ENCFF939VKA 237 bp overlap
ChIP WA01 ENCSR000BNR.HDAC2.WA01 119 bp overlap
HIC2 1 dataset
Motif ES_0h ES_0h-HIC2_MA0738.2 6 bp overlap
HOXB13 3 datasets
ChIP prostate-cancer_PDX_167 GSE130408.HOXB13.prostate-cancer_PDX_167 242 bp overlap
ChIP prostate-cancer_PDX_170-2 GSE130408.HOXB13.prostate-cancer_PDX_170-2 64 bp overlap
ChIP prostate_2030_T GSE130408.HOXB13.prostate_2030_T 50 bp overlap
HOXB8 1 dataset
ChIP CFPAC-1_HOXB8-OE GSE119930.HOXB8.CFPAC-1_HOXB8-OE 50 bp overlap
JUN 5 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 165 bp overlap
ChIP ESC S24-ESC-d0-JUN-exp1 274 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 287 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 126 bp overlap
ChIP MCF-7_Tamoxifen GSE102410.JUN.MCF-7_Tamoxifen 55 bp overlap
KLF14 1 dataset
Motif ES_0h ES_0h-KLF14_MA0740.2 9 bp overlap
KLF16 1 dataset
Motif ES_0h ES_0h-KLF16_MA0741.1 11 bp overlap
KLF4 1 dataset
ChIP PDAC GSE64557.KLF4.PDAC 432 bp overlap
KLF5 1 dataset
Motif ES_0h ES_0h-KLF5_MA0599.1 10 bp overlap
KLF9 1 dataset
Motif ES_0h ES_0h-KLF9_MA1107.3 11 bp overlap
MAFK 1 dataset
ChIP OCI-Ly7 GSE47784.MAFK.OCI-Ly7 66 bp overlap
MAX 2 datasets
ChIP H1 ENCFF601FOM 325 bp overlap
ChIP WA01 ENCSR000EUP.MAX.WA01 334 bp overlap
MAZ 1 dataset
Motif ES_0h ES_0h-MAZ_MA1522.2 8 bp overlap
MED1 2 datasets
ChIP VCaP GSE148358.MED1.VCaP 150 bp overlap
ChIP VCaP_R1881 GSE148358.MED1.VCaP_R1881 76 bp overlap
MXI1 1 dataset
ChIP WA01 ENCSR000EBR.MXI1.WA01 131 bp overlap
MYC 1 dataset
ChIP P493-6_MST-312 GSE77061.MYC.P493-6_MST-312 168 bp overlap
NANOG 3 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 597 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 184 bp overlap
ChIP hESC GSE18292.NANOG.hESC 108 bp overlap
NEUROD1 1 dataset
ChIP D283-Med GSE92582.NEUROD1.D283-Med 313 bp overlap
NUTM1 2 datasets
ChIP NUT_DMSO GSE133122.NUTM1.NUT_DMSO 292 bp overlap
ChIP NUT_DMSO GSE133122.NUTM1.NUT_DMSO 94 bp overlap
PATZ1 1 dataset
Motif ES_0h ES_0h-PATZ1_MA1961.2 11 bp overlap
PHIP 1 dataset
ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 118 bp overlap
POLR2A 1 dataset
ChIP H1 ENCFF566JSR 557 bp overlap
POU5F1 3 datasets
ChIP HUES-8 GSE109524.POU5F1.HUES-8 426 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 354 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 233 bp overlap
PRDM4 1 dataset
ChIP HEK293 ENCSR443MVV.PRDM4.HEK293 236 bp overlap
PRDM9 1 dataset
Motif ES_0h ES_0h-PRDM9_MA1723.2 20 bp overlap
RAD21 1 dataset
ChIP H1 ENCFF698EWO 241 bp overlap
RBBP5 2 datasets
ChIP WA01 ENCSR000AQC.RBBP5.WA01 168 bp overlap
ChIP WA01 ENCSR000AQC.RBBP5.WA01 326 bp overlap
RFX1 5 datasets
ChIP MCF-7 ENCFF782EZS 432 bp overlap
ChIP MCF-7 ENCFF973QAD 202 bp overlap
ChIP MCF-7 ENCFF973QAD 405 bp overlap
ChIP MCF-7 ENCSR066TET.RFX1.MCF-7 527 bp overlap
ChIP MCF-7 ENCSR788XNX.RFX1.MCF-7 385 bp overlap
SIN3A 1 dataset
ChIP H1 ENCFF042ZSL 393 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 344 bp overlap
SMAD2_3 1 dataset
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 297 bp overlap
SMARCA4 3 datasets
ChIP MCF-7 GSE140185.SMARCA4.MCF-7 433 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 197 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 235 bp overlap
SMARCB1 1 dataset
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 268 bp overlap
SMARCD3 1 dataset
ChIP MCF-7 GSE124225.SMARCD3.MCF-7 207 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 349 bp overlap
SOX2 3 datasets
ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 90 bp overlap
ChIP hESC GSE18292.SOX2.hESC 99 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 225 bp overlap
SP1 2 datasets
ChIP H1 ENCFF263FUH 189 bp overlap
ChIP WA01 ENCSR000BIR.SP1.WA01 307 bp overlap
SP3 1 dataset
Motif ES_0h ES_0h-SP3_MA0746.3 11 bp overlap
SP4 2 datasets
Motif ES_0h ES_0h-SP4_MA0685.2 9 bp overlap
ChIP WA01 ENCSR000BQV.SP4.WA01 210 bp overlap
SP5 1 dataset
Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap
SP8 1 dataset
Motif ES_0h ES_0h-SP8_MA0747.2 11 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 224 bp overlap
TAF1 3 datasets
ChIP H1 ENCFF478SZO 479 bp overlap
ChIP WA01 ENCSR000BHO.TAF1.WA01 83 bp overlap
ChIP WA01 ENCSR000BHO.TAF1.WA01 213 bp overlap
TBP 4 datasets
ChIP H1 ENCFF859IIO 296 bp overlap
ChIP H1 ENCFF859IIO 377 bp overlap
ChIP hESC GSE122298.TBP.hESC 270 bp overlap
ChIP hESC_8h GSE122298.TBP.hESC_8h 93 bp overlap
TCF12 2 datasets
ChIP H1 ENCFF203EBH 251 bp overlap
ChIP WA01 ENCSR000BIT.TCF12.WA01 320 bp overlap
TCF3 1 dataset
ChIP NPC GSE154479.TCF3.NPC 440 bp overlap
TP63 1 dataset
ChIP keratinocyte_D2 GSE59824.TP63.keratinocyte_D2 58 bp overlap
USF1 2 datasets
ChIP H1 ENCFF090WVU 241 bp overlap
ChIP WA01 ENCSR000BIU.USF1.WA01 236 bp overlap
YY1 1 dataset
ChIP WA01 ENCSR000BKD.YY1.WA01 179 bp overlap
ZBTB24 1 dataset
Motif ES_0h ES_0h-ZBTB24_MA2330.1 10 bp overlap
ZFHX2 1 dataset
ChIP HEK293 ENCFF167TUA 111 bp overlap
ZNF148 1 dataset
Motif ES_0h ES_0h-ZNF148_MA1653.2 10 bp overlap
ZNF257 1 dataset
Motif ES_0h ES_0h-ZNF257_MA1710.2 10 bp overlap
ZNF281 1 dataset
Motif ES_0h ES_0h-ZNF281_MA1630.3 10 bp overlap
ZNF35 1 dataset
Motif ES_0h ES_0h-ZNF35_MA2333.1 7 bp overlap
ZNF707 1 dataset
Motif ES_0h ES_0h-ZNF707_MA1715.1 15 bp overlap
ZNF740 1 dataset
Motif ES_0h ES_0h-ZNF740_MA0753.3 10 bp overlap
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