chr20:46,268,041–46,268,560

chr20 : 46,268,041 – 46,268,560

519 bp 82 TFs 6 linked genes

This 519 bp open chromatin element is linked to 6 target genes and is bound by 82 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
SLC35C2		96.1 kb	Distal	Multiome
ELMO2		138.3 kb	Distal	Multiome
CD40		150.0 kb	Distal	Multiome
NCOA5		178.4 kb	Distal	Multiome
ZNF334		245.3 kb	Distal	Multiome
ZNF335		296.1 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

82 transcription factors

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 135 bp overlap

ASCL1 1 dataset

ChIP NCI-H82 GSE69394.ASCL1.NCI-H82 146 bp overlap

BRD4 9 datasets

ChIP COLO-741 GSE73319.BRD4.COLO-741 295 bp overlap

ChIP HEK293T GSE51633.BRD4.HEK293T 191 bp overlap

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 329 bp overlap

ChIP Kelly_resistant_JQ1 GSE103030.BRD4.Kelly_resistant_JQ1 293 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 519 bp overlap

ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 226 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 222 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 94 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 519 bp overlap

CTCF 20 datasets

ChIP Kelly_resistant GSE103030.CTCF.Kelly_resistant 160 bp overlap

ChIP WERI-Rb-1 ENCFF349QKF 231 bp overlap

ChIP WERI-Rb-1 ENCSR000DXW.CTCF.WERI-Rb-1 237 bp overlap

ChIP adrenal-gland ENCSR770IWO.CTCF.adrenal-gland 193 bp overlap

ChIP brain ENCFF685VRG 519 bp overlap

ChIP endodermal cell ENCFF471YCZ 274 bp overlap

ChIP hESC_D2 GSE116862.CTCF.hESC_D2 226 bp overlap

ChIP hESC_D5 GSE116862.CTCF.hESC_D5 429 bp overlap

ChIP nephron ENCFF589HXU 441 bp overlap

ChIP nephron progenitor cell ENCFF455DMI 479 bp overlap

ChIP neural ENCSR822CEA.CTCF.neural 431 bp overlap

ChIP neural cell ENCFF335ADI 481 bp overlap

ChIP neural_progenitor ENCSR125NBL.CTCF.neural_progenitor 230 bp overlap

ChIP retina_AB1-FW14 GSE86981.CTCF.retina_AB1-FW14 373 bp overlap

ChIP retina_AB1-FW16 GSE86981.CTCF.retina_AB1-FW16 395 bp overlap

ChIP retina_AB1-FW23 GSE86981.CTCF.retina_AB1-FW23 265 bp overlap

ChIP retina_AB1-RB GSE86981.CTCF.retina_AB1-RB 291 bp overlap

ChIP retina_Hu25 GSE137311.CTCF.retina_Hu25 222 bp overlap

ChIP type B pancreatic cell ENCFF910FNQ 181 bp overlap

ChIP type B pancreatic cell ENCFF910FNQ 261 bp overlap

CTCFL 1 dataset

ChIP Kelly_resistant_JQ1 GSE103030.CTCFL.Kelly_resistant_JQ1 142 bp overlap

CTNNB1 1 dataset

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 188 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF031ISE 337 bp overlap

ChIP BLaER1 ENCFF335XTP 76 bp overlap

ChIP HEK293 ENCFF336LFH 261 bp overlap

ChIP GM12878 ENCSR000BMB.ELF1.GM12878 148 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 358 bp overlap

ESRRA 2 datasets

ChIP BT-474 GSE81651.ESRRA.BT-474 55 bp overlap

ChIP SK-BR-3_HRG GSE81651.ESRRA.SK-BR-3_HRG 55 bp overlap

EZH2 4 datasets

ChIP Hep-3B2-1-7 GSE128137.EZH2.Hep-3B2-1-7 323 bp overlap

ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 198 bp overlap

ChIP PC-9 ENCSR793USK.EZH2.PC-9 281 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 192 bp overlap

EZH2_phosphoT487 1 dataset

ChIP PC-9 ENCSR702GMW.EZH2_phosphoT487.PC-9 357 bp overlap

FOXA1 1 dataset

ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 429 bp overlap

GATA1 1 dataset

ChIP erythroid-progenitor GSE124163.GATA1.erythroid-progenitor 132 bp overlap

GATA2 3 datasets

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 376 bp overlap

ChIP SH-SY5Y ENCFF485YIB 405 bp overlap

ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 246 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 420 bp overlap

ChIP DE DE-GATA4-2 458 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-2 471 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 384 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 492 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 519 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 519 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 519 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 519 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 405 bp overlap

GLIS1 1 dataset

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 201 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 282 bp overlap

GRHL2 1 dataset

ChIP OVCAR-3 GSE71018.GRHL2.OVCAR-3 192 bp overlap

HAND2 1 dataset

ChIP Kelly GSE94822.HAND2.Kelly 150 bp overlap

HIVEP1 1 dataset

ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 224 bp overlap

HNRNPH1 1 dataset

ChIP Hep-G2 GSE120104.HNRNPH1.Hep-G2 69 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 383 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 471 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 318 bp overlap

ChIP MDA-MB-231 GSE112444.JUN.MDA-MB-231 194 bp overlap

ChIP WTC11 ENCFF172UDA 361 bp overlap

KDM1A 1 dataset

ChIP HepG2 ENCFF240UWG 52 bp overlap

KDM4C 1 dataset

ChIP KYSE-150 GSE53938.KDM4C.KYSE-150 221 bp overlap

KLF17 1 dataset

ChIP HEK293 ENCSR065WUF.KLF17.HEK293 262 bp overlap

KLF5 2 datasets

ChIP HEK293_E419K GSE88976.KLF5.HEK293_E419K 262 bp overlap

ChIP HEK293_E419Q GSE88976.KLF5.HEK293_E419Q 277 bp overlap

L3MBTL2 1 dataset

ChIP HEK293T ENCFF482NJV 186 bp overlap

MED1 3 datasets

ChIP SGBS GSE64233.MED1.SGBS 374 bp overlap

ChIP SGBS_TNF GSE64233.MED1.SGBS_TNF 358 bp overlap

ChIP hMSC-TERT4_adipocyte-D14 GSE113253.MED1.hMSC-TERT4_adipocyte-D14 299 bp overlap

ChIP HepG2 ENCFF575FXK 129 bp overlap

MYCN 4 datasets

ChIP CHP-134 GSE129588.MYCN.CHP-134 329 bp overlap

ChIP Kelly GSE94782.MYCN.Kelly 196 bp overlap

ChIP Kelly_sensitive GSE115249.MYCN.Kelly_sensitive 381 bp overlap

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 439 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 228 bp overlap

NCOR1 1 dataset

ChIP HEK293T_SICTR GSE35197.NCOR1.HEK293T_SICTR 205 bp overlap

NEUROD1 5 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 239 bp overlap

ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 253 bp overlap

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 488 bp overlap

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 519 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 519 bp overlap

OSR2 3 datasets

ChIP HEK293 ENCFF875BDB 364 bp overlap

ChIP HEK293 ENCFF875BDB 164 bp overlap

ChIP HEK293 ENCSR324LTM.OSR2.HEK293 352 bp overlap

ChIP myometrium_NP1 GSE137550.PGR.myometrium_NP1 180 bp overlap

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 154 bp overlap

PITX3 1 dataset

ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 307 bp overlap

PKNOX1 2 datasets

ChIP HEK293T ENCFF174WDB 106 bp overlap

ChIP HEK293T ENCSR233FAG.PKNOX1.HEK293T 269 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 386 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 412 bp overlap

PTBP1 1 dataset

ChIP Hep-G2 ENCSR156APP.PTBP1.Hep-G2 232 bp overlap

ChIP SGBS GSE64233.RELA.SGBS 317 bp overlap

ChIP neural ENCSR000BTV.REST.neural 314 bp overlap

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 198 bp overlap

SIX2 3 datasets

ChIP HEK GSE73865.SIX2.HEK 217 bp overlap

ChIP kidney_fetal_16w GSE75948.SIX2.kidney_fetal_16w 178 bp overlap

ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 215 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 350 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 519 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 519 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 519 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 446 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 519 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 519 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 519 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 519 bp overlap

SMAD3 2 datasets

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 255 bp overlap

ChIP endoderm GSE29422.SMAD3.endoderm 246 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 335 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 246 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 250 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 416 bp overlap

ChIP HNSC GSE69479.SOX2.HNSC 229 bp overlap

ChIP HEK293 ENCFF733RBE 390 bp overlap

ChIP HEK293 ENCSR468IJT.SP7.HEK293 519 bp overlap

SUZ12 2 datasets

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 413 bp overlap

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 519 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 355 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 251 bp overlap

TBL1X 1 dataset

ChIP HEK293T GSE35197.TBL1X.HEK293T 366 bp overlap

ChIP Kelly GSE94822.TBX2.Kelly 195 bp overlap

TRIM28 1 dataset

ChIP AF22 GSE84259.TRIM28.AF22 241 bp overlap

ChIP HEK293 ENCFF906HIR 184 bp overlap

ChIP HEK293 ENCSR966PJJ.WT1.HEK293 288 bp overlap

ChIP HEK293 ENCSR859RAO.YY1.HEK293 222 bp overlap

ChIP Hep-G2_NC GSE120104.YY1.Hep-G2_NC 243 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 318 bp overlap

ZBTB7A 1 dataset

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 254 bp overlap

ZBTB8A 2 datasets

ChIP HEK293 ENCFF303WRD 376 bp overlap

ChIP HEK293 ENCSR481FEC.ZBTB8A.HEK293 519 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 341 bp overlap

ZFP64 1 dataset

ChIP HEK293 GSE76494.ZFP64.HEK293 147 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 519 bp overlap

ChIP HEK293 ENCFF033NQQ 519 bp overlap

ZNF189 1 dataset

ChIP HEK293 ENCSR163RYW.ZNF189.HEK293 392 bp overlap

ZNF257 1 dataset

ChIP HEK293T GSE78099.ZNF257.HEK293T 126 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 237 bp overlap

ZNF317 1 dataset

ChIP HEK293 GSE76494.ZNF317.HEK293 147 bp overlap

ZNF341 3 datasets

ChIP HEK293 ENCFF944VMC 147 bp overlap

ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 97 bp overlap

ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 219 bp overlap

ZNF394 1 dataset

ChIP HEK293 ENCSR125DNC.ZNF394.HEK293 247 bp overlap

ZNF423 3 datasets

ChIP HEK293 ENCFF937QHI 357 bp overlap

ChIP HEK293 ENCSR477OJI.ZNF423.HEK293 290 bp overlap

ChIP WTC11 ENCFF574PBR 317 bp overlap

ZNF561 1 dataset

ChIP HEK293 ENCSR125ULS.ZNF561.HEK293 270 bp overlap

ZNF711 1 dataset

ChIP HEK293T GSE145160.ZNF711.HEK293T 519 bp overlap

ZNF891 1 dataset

ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 183 bp overlap