chr17:60,384,860–60,385,543

chr17 : 60,384,860 – 60,385,543

683 bp 76 TFs 8 linked genes

This 683 bp open chromatin element is linked to 8 target genes and is bound by 76 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
USP32		6.6 kb	Proximal	Proximity
CHCT1		6.9 kb	Proximal	Proximity
APPBP2		140.8 kb	Distal	Multiome
APPBP2-DT		141.1 kb	Distal	Multiome
PPM1D		215.0 kb	Distal	Multiome
CA4		235.2 kb	Distal	Multiome
ENSG00000267248		249.4 kb	Distal	Multiome
BCAS3		292.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

76 transcription factors

ARID3A 1 dataset

ChIP HepG2 ENCFF341DES 296 bp overlap

ARID5B 1 dataset

ChIP HepG2 ENCFF964FWK 228 bp overlap

ChIP HepG2 ENCFF903ADR 240 bp overlap

Atoh1 1 dataset

Motif DE_12h DE_12h-Atoh1_MA1467.3 7 bp overlap

Bcl11B 2 datasets

Motif DE_12h DE_12h-Bcl11B_MA1989.2 9 bp overlap

Motif ES_0h ES_0h-Bcl11B_MA1989.2 9 bp overlap

CBFA2T3 1 dataset

ChIP K562 ENCFF673OEZ 343 bp overlap

CEBPA 1 dataset

ChIP HepG2 ENCFF175DFS 157 bp overlap

CEBPB 7 datasets

ChIP H1 ENCFF871PTR 160 bp overlap

ChIP HepG2 ENCFF074JWB 155 bp overlap

ChIP HepG2 ENCFF536NTI 174 bp overlap

ChIP IMR-90 ENCFF468UGY 189 bp overlap

ChIP K562 ENCFF189VBN 101 bp overlap

ChIP K562 ENCFF194QGF 195 bp overlap

ChIP K562 ENCFF584CTB 187 bp overlap

CEBPD 1 dataset

ChIP HepG2 ENCFF345JDB 205 bp overlap

CEBPG 3 datasets

ChIP HepG2 ENCFF503XBC 146 bp overlap

ChIP K562 ENCFF783ADE 307 bp overlap

ChIP K562 ENCFF956TPS 311 bp overlap

Cebpa 10 datasets

ChIP BLaER1 ENCFF031ISE 416 bp overlap

ChIP BLaER1 ENCFF093OYK 256 bp overlap

ChIP BLaER1 ENCFF274GAT 491 bp overlap

ChIP BLaER1 ENCFF335XTP 126 bp overlap

ChIP BLaER1 ENCFF341QPD 230 bp overlap

ChIP BLaER1 ENCFF364PUR 311 bp overlap

ChIP BLaER1 ENCFF460KDD 257 bp overlap

ChIP BLaER1 ENCFF798NMV 92 bp overlap

ChIP BLaER1 ENCFF844FIP 170 bp overlap

ChIP BLaER1 ENCFF896HSY 274 bp overlap

Motif DE_12h DE_12h-Dux_MA0611.3 11 bp overlap

Motif ES_0h ES_0h-Dux_MA0611.3 11 bp overlap

EGR1 2 datasets

ChIP Hep-G2 ENCSR026GSW.EGR1.Hep-G2 197 bp overlap

ChIP K562 ENCFF006PJY 61 bp overlap

FLI1::DRGX 2 datasets

Motif DE_12h DE_12h-FLI1DRGX_MA1949.2 14 bp overlap

Motif ES_0h ES_0h-FLI1DRGX_MA1949.2 14 bp overlap

FOXA1 1 dataset

ChIP HepG2 ENCFF740VZW 165 bp overlap

FOXA2 1 dataset

ChIP HepG2 ENCFF894AYY 190 bp overlap

GATAD2A 1 dataset

ChIP HepG2 ENCFF252XNH 83 bp overlap

GFI1 3 datasets

Motif DE_12h DE_12h-GFI1_MA0038.3 11 bp overlap

Motif ES_0h ES_0h-GFI1_MA0038.3 11 bp overlap

ChIP HepG2 ENCFF472INF 344 bp overlap

HAND2 1 dataset

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

HDAC1 1 dataset

ChIP HepG2 ENCFF304IEJ 446 bp overlap

HNF1B 1 dataset

ChIP HepG2 ENCFF928THX 305 bp overlap

HNF4A 3 datasets

ChIP gastric-epithelial-cell_OE GSE114018.HNF4A.gastric-epithelial-cell_OE 141 bp overlap

ChIP liver ENCFF354NRH 117 bp overlap

ChIP liver ENCFF449HPV 155 bp overlap

IKZF1 2 datasets

Motif DE_12h DE_12h-IKZF1_MA1508.2 8 bp overlap

Motif ES_0h ES_0h-IKZF1_MA1508.2 8 bp overlap

IKZF5 2 datasets

ChIP HepG2 ENCFF641EBK 309 bp overlap

ChIP HepG2 ENCFF641EBK 99 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 683 bp overlap

KMT2B 2 datasets

ChIP HepG2 ENCFF675TEK 397 bp overlap

ChIP HepG2 ENCFF675TEK 193 bp overlap

ChIP HepG2 ENCFF507HCX 319 bp overlap

MEIS1 4 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

Motif DE_12h DE_12h-MEIS1_MA1639.2 9 bp overlap

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MEIS1_MA1639.2 9 bp overlap

MEIS2 2 datasets

Motif DE_12h DE_12h-MEIS2_MA1640.2 9 bp overlap

Motif ES_0h ES_0h-MEIS2_MA1640.2 9 bp overlap

Motif DE_12h DE_12h-MYB_MA0100.4 6 bp overlap

NANOG 3 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 265 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 247 bp overlap

NEUROG2 1 dataset

Motif DE_12h DE_12h-NEUROG2_MA1642.2 7 bp overlap

NFE2L1 1 dataset

ChIP WTC11 ENCFF644BPU 341 bp overlap

NFXL1 2 datasets

ChIP GM12878 ENCFF513WDR 229 bp overlap

ChIP GM12878 ENCSR746XEG.NFXL1.GM12878 213 bp overlap

NR2F2 4 datasets

ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 130 bp overlap

ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 171 bp overlap

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 106 bp overlap

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 174 bp overlap

ChIP HEK293 ENCFF875BDB 127 bp overlap

PBX2 2 datasets

Motif DE_12h DE_12h-PBX2_MA1113.3 9 bp overlap

Motif ES_0h ES_0h-PBX2_MA1113.3 9 bp overlap

POU2F1::SOX2 2 datasets

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 468 bp overlap

ChIP GM23338 ENCFF333SNB 311 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 349 bp overlap

PRDM10 1 dataset

ChIP HEK293 ENCFF145WQQ 94 bp overlap

PROX1 1 dataset

ChIP HepG2 ENCFF016ZJS 143 bp overlap

RAD21 1 dataset

ChIP HepG2 ENCFF360ZSW 87 bp overlap

SALL1 1 dataset

ChIP HepG2 ENCFF426MCK 296 bp overlap

SAP130 1 dataset

ChIP HepG2 ENCFF892EHZ 281 bp overlap

SMAD4 1 dataset

ChIP HepG2 ENCFF615GTE 152 bp overlap

SOX13 3 datasets

Motif DE_12h DE_12h-SOX13_MA1120.2 7 bp overlap

Motif ES_0h ES_0h-SOX13_MA1120.2 7 bp overlap

ChIP HepG2 ENCFF062VSQ 186 bp overlap

SOX2 2 datasets

Motif DE_12h DE_12h-SOX2_MA0143.5 7 bp overlap

Motif ES_0h ES_0h-SOX2_MA0143.5 7 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

Sox17 2 datasets

Motif DE_12h DE_12h-Sox17_MA0078.3 10 bp overlap

Motif ES_0h ES_0h-Sox17_MA0078.3 10 bp overlap

Sox3 2 datasets

Motif DE_12h DE_12h-Sox3_MA0514.3 7 bp overlap

Motif ES_0h ES_0h-Sox3_MA0514.3 7 bp overlap

TEAD1 3 datasets

Motif DE_12h DE_12h-TEAD1_MA0090.4 9 bp overlap

Motif ES_0h ES_0h-TEAD1_MA0090.4 9 bp overlap

ChIP WTC11 ENCFF502QUV 405 bp overlap

TEAD2 2 datasets

Motif DE_12h DE_12h-TEAD2_MA1121.2 7 bp overlap

Motif ES_0h ES_0h-TEAD2_MA1121.2 7 bp overlap

TEAD3 2 datasets

Motif DE_12h DE_12h-TEAD3_MA0808.1 8 bp overlap

Motif ES_0h ES_0h-TEAD3_MA0808.1 8 bp overlap

TEAD4 3 datasets

Motif DE_12h DE_12h-TEAD4_MA0809.3 8 bp overlap

Motif ES_0h ES_0h-TEAD4_MA0809.3 8 bp overlap

ChIP H1 ENCFF778PAX 245 bp overlap

TFAP4::FLI1 1 dataset

Motif DE_12h DE_12h-TFAP4FLI1_MA1967.2 14 bp overlap

USF1 4 datasets

ChIP H1 ENCFF090WVU 241 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 146 bp overlap

ChIP WTC11 ENCFF699QGS 425 bp overlap

ChIP WTC11 ENCFF699QGS 331 bp overlap

ChIP WTC11 ENCFF139JAW 417 bp overlap

ChIP H1 ENCFF524BTL 337 bp overlap

ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 147 bp overlap

ZBTB11 1 dataset

ChIP K562 ENCFF694AXU 213 bp overlap

ZBTB33 4 datasets

ChIP HepG2 ENCFF778UKV 148 bp overlap

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 174 bp overlap

ChIP K562 ENCFF875HLX 279 bp overlap

ChIP K562 ENCFF875HLX 79 bp overlap

ZBTB38 1 dataset

ChIP HepG2 ENCFF875UQX 324 bp overlap

ZBTB4 1 dataset

ChIP HepG2 ENCFF828GZH 436 bp overlap

ChIP MCF-7 GSE102616.ZFX.MCF-7 136 bp overlap

ZKSCAN8 1 dataset

ChIP K562 ENCFF387ETI 142 bp overlap

ZMYM3 1 dataset

ChIP HepG2 ENCFF408KTI 334 bp overlap

ZMYM4 1 dataset

ChIP HepG2 ENCFF567SQY 324 bp overlap

ZNF121 2 datasets

ChIP Hep-G2 ENCSR945QEW.ZNF121.Hep-G2 175 bp overlap

ChIP HepG2 ENCFF343YSL 155 bp overlap

ZNF232 2 datasets

ChIP WTC11 ENCFF901BGD 461 bp overlap

ChIP WTC11 ENCFF901BGD 429 bp overlap

ZNF292 1 dataset

ChIP HepG2 ENCFF975MAJ 275 bp overlap

ZNF418 1 dataset

Motif DE_12h DE_12h-ZNF418_MA1980.1 15 bp overlap

ZNF460 1 dataset

ChIP HepG2 ENCFF007NNM 289 bp overlap

ZNF501 1 dataset

ChIP HepG2 ENCFF879XZR 597 bp overlap

ZNF547 1 dataset

ChIP HepG2 ENCFF834XWI 452 bp overlap

ZNF75A 2 datasets

Motif DE_12h DE_12h-ZNF75A_MA2097.1 12 bp overlap

Motif ES_0h ES_0h-ZNF75A_MA2097.1 12 bp overlap

ZNF770 2 datasets

ChIP Hep-G2 ENCSR510GKB.ZNF770.Hep-G2 218 bp overlap

ChIP HepG2 ENCFF233UVH 375 bp overlap