chr17:57,750,076–57,750,566

chr17 : 57,750,076 – 57,750,566

490 bp 85 TFs 7 linked genes

This 490 bp open chromatin element is linked to 7 target genes and is bound by 85 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
MRPS23		99.7 kb	Distal	Multiome
CUEDC1		142.4 kb	Distal	Multiome
VEZF1		238.0 kb	Distal	Multiome
ENSG00000264112		244.5 kb	Distal	Multiome
SRSF1		257.0 kb	Distal	Multiome
MSI2		493.8 kb	Distal	Multiome+HiCAR
AKAP1		665.1 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

85 transcription factors

BRD2 4 datasets

ChIP THP-1_DMSO GSE138084.BRD2.THP-1_DMSO 378 bp overlap

ChIP THP-1_iBET GSE138084.BRD2.THP-1_iBET 490 bp overlap

ChIP THP-1_iBET-BD1 GSE138084.BRD2.THP-1_iBET-BD1 418 bp overlap

ChIP THP-1_iBET-BD2 GSE138084.BRD2.THP-1_iBET-BD2 251 bp overlap

BRD4 9 datasets

ChIP KOPT-K1 GSE54379.BRD4.KOPT-K1 444 bp overlap

ChIP KOPT-K1_E GSE54379.BRD4.KOPT-K1_E 490 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 169 bp overlap

ChIP MOLM-14_DMSO GSE65138.BRD4.MOLM-14_DMSO 490 bp overlap

ChIP MOLM-14_IBET GSE65138.BRD4.MOLM-14_IBET 414 bp overlap

ChIP MV4-11-B_BI00894999_35nM_4h GSE101821.BRD4.MV4-11-B_BI00894999_35nM_4h 257 bp overlap

ChIP MV4-11-B_DMSO GSE101821.BRD4.MV4-11-B_DMSO 365 bp overlap

ChIP MV4-11_DMSO GSE71776.BRD4.MV4-11_DMSO 417 bp overlap

ChIP SEM GSE83671.BRD4.SEM 490 bp overlap

CBFA2T3 1 dataset

ChIP Kasumi-1 GSE126953.CBFA2T3.Kasumi-1 305 bp overlap

CDK8 2 datasets

ChIP MOLM-14 GSE65138.CDK8.MOLM-14 379 bp overlap

ChIP MOLM-14_IBET GSE65138.CDK8.MOLM-14_IBET 397 bp overlap

ChIP MV4-11_DMSO GSE82116.CDK9.MV4-11_DMSO 216 bp overlap

CEBPA 4 datasets

ChIP Kasumi-1_CEBPA-ER GSE102697.CEBPA.Kasumi-1_CEBPA-ER 164 bp overlap

ChIP Kasumi-1_CEBPA-ER_E2 GSE102697.CEBPA.Kasumi-1_CEBPA-ER_E2 218 bp overlap

ChIP Kasumi-1_SIRUNX1ETO GSE60130.CEBPA.Kasumi-1_SIRUNX1ETO 210 bp overlap

ChIP MV4-11 GSE88746.CEBPA.MV4-11 457 bp overlap

CEBPB 1 dataset

ChIP MV4-11 GSE88746.CEBPB.MV4-11 463 bp overlap

Cebpa 12 datasets

ChIP BLaER1 ENCFF031ISE 490 bp overlap

ChIP BLaER1 ENCFF093OYK 490 bp overlap

ChIP BLaER1 ENCFF274GAT 399 bp overlap

ChIP BLaER1 ENCFF335XTP 485 bp overlap

ChIP BLaER1 ENCFF341QPD 421 bp overlap

ChIP BLaER1 ENCFF341QPD 268 bp overlap

ChIP BLaER1 ENCFF364PUR 490 bp overlap

ChIP BLaER1 ENCFF399AYC 461 bp overlap

ChIP BLaER1 ENCFF508JZF 441 bp overlap

ChIP BLaER1 ENCFF844FIP 439 bp overlap

ChIP BLaER1 ENCFF858JKM 218 bp overlap

ChIP BLaER1 ENCFF952XLX 376 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 215 bp overlap

EP300 1 dataset

ChIP AML GSE131939.EP300.AML 309 bp overlap

ChIP AMLPZ12 GSE23730.ERG.AMLPZ12 106 bp overlap

ChIP HUVEC-C GSE124891.ERG.HUVEC-C 149 bp overlap

ChIP ME-1 GSE46044.ERG.ME-1 430 bp overlap

ChIP SEM GSE117864.ERG.SEM 407 bp overlap

ChIP SKNO-1 GSE23730.ERG.SKNO-1 391 bp overlap

ChIP TSU-1621MT GSE60477.ERG.TSU-1621MT 483 bp overlap

ChIP TSU-1621MT_ATRA GSE60477.ERG.TSU-1621MT_ATRA 454 bp overlap

ChIP aortic-endothelial-cell_D39 GSE139377.ERG.aortic-endothelial-cell_D39 118 bp overlap

ChIP aortic-endothelial-cell_D39 GSE139377.ERG.aortic-endothelial-cell_D39 157 bp overlap

ESR1 3 datasets

ChIP Ishikawa_E2-1h GSE129803.ESR1.Ishikawa_E2-1h 224 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 174 bp overlap

ChIP MCF-7_aldosterone GSE99626.ESR1.MCF-7_aldosterone 325 bp overlap

ETS1 5 datasets

ChIP CTV-1_DSG GSE128835.ETS1.CTV-1_DSG 402 bp overlap

ChIP CTV-1_DSG_SPI1-mut GSE128835.ETS1.CTV-1_DSG_SPI1-mut 400 bp overlap

ChIP HUVEC-C_4h GSE93030.ETS1.HUVEC-C_4h 217 bp overlap

ChIP HUVEC-C_VEGF_4H GSE41166.ETS1.HUVEC-C_VEGF_4H 255 bp overlap

ChIP HUVEC-C_VEGF_4h GSE109625.ETS1.HUVEC-C_VEGF_4h 217 bp overlap

EVI1 2 datasets

ChIP SKH1 GSE87283.EVI1.SKH1 268 bp overlap

ChIP SKH1_10d GSE87283.EVI1.SKH1_10d 204 bp overlap

ChIP RH30_DMSO GSE85169.EZH2.RH30_DMSO 190 bp overlap

FLI1 9 datasets

ChIP CTV-1_DSG GSE128835.FLI1.CTV-1_DSG 346 bp overlap

ChIP CTV-1_DSG_SPI1-mut GSE128835.FLI1.CTV-1_DSG_SPI1-mut 362 bp overlap

ChIP HUVEC-C GSE109695.FLI1.HUVEC-C 183 bp overlap

ChIP NB4 GSE23730.FLI1.NB4 282 bp overlap

ChIP SEM GSE117864.FLI1.SEM 407 bp overlap

ChIP SKNO-1 GSE23730.FLI1.SKNO-1 432 bp overlap

ChIP TSU-1621MT GSE60477.FLI1.TSU-1621MT 261 bp overlap

ChIP UAE GSE23730.FLI1.UAE 394 bp overlap

ChIP UAE_ZINC GSE23730.FLI1.UAE_ZINC 437 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-1 240 bp overlap

FOXO1 1 dataset

ChIP CD34 GSE80773.FOXO1.CD34 410 bp overlap

GATA2 4 datasets

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 442 bp overlap

ChIP SKH1 GSE87283.GATA2.SKH1 306 bp overlap

ChIP SKH1_RUNX1-EVI1_KD GSE87283.GATA2.SKH1_RUNX1-EVI1_KD 183 bp overlap

ChIP TSU-1621MT GSE60477.GATA2.TSU-1621MT 241 bp overlap

GATA4 1 dataset

ChIP DE DE-GATA4-2 376 bp overlap

GATA6 9 datasets

ChIP AGS GSE51936.GATA6.AGS 79 bp overlap

ChIP DE DE-GATA6-1 234 bp overlap

ChIP DE DE-GATA6-2 420 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 410 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 490 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 458 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 490 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 490 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 458 bp overlap

GATAD2B 1 dataset

ChIP MCF-7 ENCSR979FQP.GATAD2B.MCF-7 61 bp overlap

HDAC3 1 dataset

ChIP AML_shaml1-eto GSE131939.HDAC3.AML_shaml1-eto 147 bp overlap

HSF1 3 datasets

ChIP MO91 GSE45852.HSF1.MO91 243 bp overlap

ChIP MO91_27A_20UM GSE45852.HSF1.MO91_27A_20UM 240 bp overlap

ChIP MO91_CHX_10UM GSE45852.HSF1.MO91_CHX_10UM 223 bp overlap

IKZF1 2 datasets

ChIP BCR-ABL1_LAX2 GSE58825.IKZF1.BCR-ABL1_LAX2 354 bp overlap

ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 381 bp overlap

IKZF3 1 dataset

ChIP pre-B-cell GSE107886.IKZF3.pre-B-cell 331 bp overlap

JMJD1C 4 datasets

ChIP HL-60 GSE63484.JMJD1C.HL-60 301 bp overlap

ChIP Kasumi-1 GSE63484.JMJD1C.Kasumi-1 379 bp overlap

ChIP NB4 GSE63484.JMJD1C.NB4 182 bp overlap

ChIP THP-1 GSE63484.JMJD1C.THP-1 149 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 293 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 279 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 418 bp overlap

ChIP OCI-AML-3 GSE133516.KAT7.OCI-AML-3 97 bp overlap

KDM1A 5 datasets

ChIP Kasumi-1_DMSO GSE71739.KDM1A.Kasumi-1_DMSO 167 bp overlap

ChIP Kasumi-1_GSK690 GSE71739.KDM1A.Kasumi-1_GSK690 217 bp overlap

ChIP Kasumi-1_RN1 GSE71739.KDM1A.Kasumi-1_RN1 216 bp overlap

ChIP NB4_DMSO GSE128528.KDM1A.NB4_DMSO 488 bp overlap

ChIP SET-2_GSK GSE121424.KDM1A.SET-2_GSK 150 bp overlap

KMT2A 3 datasets

ChIP L826 GSE83671.KMT2A.L826 431 bp overlap

ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 370 bp overlap

ChIP SEM GSE83671.KMT2A.SEM 142 bp overlap

KMT2B 2 datasets

ChIP AML GSE112074.KMT2B.AML 468 bp overlap

ChIP AML_OG86 GSE112074.KMT2B.AML_OG86 476 bp overlap

LDB1 2 datasets

ChIP Kasumi-1_ctrl GSE121280.LDB1.Kasumi-1_ctrl 338 bp overlap

ChIP Kasumi-1_siRE GSE121280.LDB1.Kasumi-1_siRE 314 bp overlap

ChIP Jurkat GSE94391.LMO1.Jurkat 255 bp overlap

LMO2 3 datasets

ChIP Kasumi-1_SICTR GSE60130.LMO2.Kasumi-1_SICTR 407 bp overlap

ChIP Kasumi-1_SIRUNX1ETO GSE60130.LMO2.Kasumi-1_SIRUNX1ETO 404 bp overlap

ChIP TSU-1621MT GSE60477.LMO2.TSU-1621MT 487 bp overlap

ChIP TSU-1621MT GSE60477.LYL1.TSU-1621MT 395 bp overlap

ChIP SEM GSE83671.MED.SEM 490 bp overlap

ChIP HepG2 ENCFF996XNT 104 bp overlap

ChIP DU528 GSE94000.MYB.DU528 447 bp overlap

ChIP Jurkat GSE59657.MYB.Jurkat 303 bp overlap

ChIP Loucy GSE94000.MYB.Loucy 490 bp overlap

ChIP MOLT-3 GSE59657.MYB.MOLT-3 139 bp overlap

ChIP THP-1 GSE90769.MYB.THP-1 490 bp overlap

ChIP THP-1_OG86 GSE90769.MYB.THP-1_OG86 438 bp overlap

ChIP MCF-7 ENCFF767RTQ 194 bp overlap

ChIP P493-6_scramble-shRNA GSE101853.MYC.P493-6_scramble-shRNA 174 bp overlap

ChIP NB-1643 GSE138295.MYCN.NB-1643 215 bp overlap

NCOR2 1 dataset

ChIP AML_shaml1-eto GSE131939.NCOR2.AML_shaml1-eto 287 bp overlap

NELFE 1 dataset

ChIP K-562_HS GSE112379.NELFE.K-562_HS 177 bp overlap

NEUROD1 1 dataset

ChIP D283-Med GSE92582.NEUROD1.D283-Med 150 bp overlap

ChIP ProEs GSE59087.NFE2.ProEs 252 bp overlap

NR4A1 1 dataset

ChIP Kasumi-1 GSE79491.NR4A1.Kasumi-1 177 bp overlap

NUTM1 1 dataset

ChIP embryonic-kidney_induced GSE133122.NUTM1.embryonic-kidney_induced 223 bp overlap

PAX3-FOXO1 1 dataset

ChIP Hs-352-Sk_PAX3-FOXO1-vector GSE83725.PAX3-FOXO1.Hs-352-Sk_PAX3-FOXO1-vector 346 bp overlap

ChIP RCH-ACV GSE85988.PBX1.RCH-ACV 270 bp overlap

ChIP HepG2 ENCFF604YOT 106 bp overlap

ChIP NB4 GSE126720.PML.NB4 205 bp overlap

POLR2A 2 datasets

ChIP MCF-7 ENCFF309IKZ 284 bp overlap

ChIP MCF-7 ENCFF411WCU 331 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 369 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 128 bp overlap

RAD21 1 dataset

ChIP THP-1_PMA_IFNb-6h GSE103477.RAD21.THP-1_PMA_IFNb-6h 288 bp overlap

ChIP TSU-1621MT GSE60477.RARA.TSU-1621MT 328 bp overlap

ChIP hiPSC_IB12 GSE106870.REST.hiPSC_IB12 104 bp overlap

ChIP ME-1_Con GSE128771.RNF2.ME-1_Con 267 bp overlap

RUNX1 14 datasets

ChIP Kasumi-1 GSE45738.RUNX1.Kasumi-1 490 bp overlap

ChIP Kasumi-1 GSE62847.RUNX1.Kasumi-1 433 bp overlap

ChIP Kasumi-1 GSE65427.RUNX1.Kasumi-1 399 bp overlap

ChIP ME-1 GSE46044.RUNX1.ME-1 427 bp overlap

ChIP ME-1 GSE117138.RUNX1.ME-1 357 bp overlap

ChIP ME-1_CBFB-MYH11-KD GSE117138.RUNX1.ME-1_CBFB-MYH11-KD 260 bp overlap

ChIP ME-1_Con GSE128771.RUNX1.ME-1_Con 260 bp overlap

ChIP ME-1_KD GSE128771.RUNX1.ME-1_KD 357 bp overlap

ChIP MV4-11 GSE79899.RUNX1.MV4-11 297 bp overlap

ChIP NALM-6 GSE126300.RUNX1.NALM-6 300 bp overlap

ChIP NB4 GSE81992.RUNX1.NB4 425 bp overlap

ChIP SKH1 GSE87283.RUNX1.SKH1 286 bp overlap

ChIP SKH1_RUNX1-EVI1_KD GSE87283.RUNX1.SKH1_RUNX1-EVI1_KD 260 bp overlap

ChIP SKNO-1 GSE23730.RUNX1.SKNO-1 245 bp overlap

RUNX1-RUNX1T1 1 dataset

ChIP AML GSE131939.RUNX1-RUNX1T1.AML 261 bp overlap

RUNX1T1 8 datasets

ChIP CD34 GSE80773.RUNX1T1.CD34 230 bp overlap

ChIP Kasumi-1 GSE115115.RUNX1T1.Kasumi-1 471 bp overlap

ChIP Kasumi-1 GSE65427.RUNX1T1.Kasumi-1 362 bp overlap

ChIP Kasumi-1 GSE102697.RUNX1T1.Kasumi-1 354 bp overlap

ChIP Kasumi-1_CEBPA-ER GSE102697.RUNX1T1.Kasumi-1_CEBPA-ER 427 bp overlap

ChIP Kasumi-1_CEBPA-ER_E2 GSE102697.RUNX1T1.Kasumi-1_CEBPA-ER_E2 272 bp overlap

ChIP Kasumi-1_shControl-AE GSE115115.RUNX1T1.Kasumi-1_shControl-AE 423 bp overlap

ChIP Kasumi-1_shTAF1-AE GSE115115.RUNX1T1.Kasumi-1_shTAF1-AE 387 bp overlap

RUNX2 1 dataset

ChIP PER-117 GSE151819.RUNX2.PER-117 221 bp overlap

ChIP macrophage ERP008801.RXR.macrophage 305 bp overlap

ChIP HL-60 GSE107553.SKI.HL-60 199 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 162 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 490 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 490 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 490 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 490 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 490 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 490 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 490 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 210 bp overlap

SMARCA4 1 dataset

ChIP CTV-1_DSG GSE128835.SMARCA4.CTV-1_DSG 410 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 207 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 372 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 490 bp overlap

SPI1 14 datasets

ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 345 bp overlap

ChIP CTV-1_delQ GSE128835.SPI1.CTV-1_delQ 253 bp overlap

ChIP CTV-1_delQA GSE128835.SPI1.CTV-1_delQA 173 bp overlap

ChIP EM-3 GSE128834.SPI1.EM-3 190 bp overlap

ChIP Kasumi-1_SICTR GSE60130.SPI1.Kasumi-1_SICTR 281 bp overlap

ChIP Kasumi-1_SIRUNX1ETO GSE60130.SPI1.Kasumi-1_SIRUNX1ETO 333 bp overlap

ChIP NB4 GSE128834.SPI1.NB4 184 bp overlap

ChIP OCI-Ly7 GSE69558.SPI1.OCI-Ly7 130 bp overlap

ChIP THP-1 GSE128834.SPI1.THP-1 137 bp overlap

ChIP THP-1_DIFF GSE25426.SPI1.THP-1_DIFF 247 bp overlap

ChIP U-937 GSE128834.SPI1.U-937 212 bp overlap

ChIP macrophage_D7_donorP GSE128834.SPI1.macrophage_D7_donorP 194 bp overlap

ChIP primary-monocyte_donorA_ncMO GSE128834.SPI1.primary-monocyte_donorA_ncMO 94 bp overlap

ChIP primary-neutrophil_donorF GSE128834.SPI1.primary-neutrophil_donorF 136 bp overlap

SRSF3 1 dataset

ChIP Hep-G2 GSE120104.SRSF3.Hep-G2 128 bp overlap

ChIP SYO-1_shCt GSE139053.SS18.SYO-1_shCt 214 bp overlap

TAL1 3 datasets

ChIP CHRF28811 ERP008568.TAL1.CHRF28811 346 bp overlap

ChIP MOLT-3 GSE59657.TAL1.MOLT-3 411 bp overlap

ChIP TSU-1621MT GSE60477.TAL1.TSU-1621MT 399 bp overlap

TCF12 2 datasets

ChIP Kasumi-1 GSE23730.TCF12.Kasumi-1 430 bp overlap

ChIP ME-1 GSE46044.TCF12.ME-1 483 bp overlap

TCF3 3 datasets

ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 346 bp overlap

ChIP RCH-ACV GSE85988.TCF3.RCH-ACV 490 bp overlap

ChIP SEM GSE85988.TCF3.SEM 347 bp overlap

TFAP4 1 dataset

ChIP Kasumi-1 GSE45738.TFAP4.Kasumi-1 350 bp overlap

ChIP THP-1_1d_1-25-OH-2D3 GSE89431.VDR.THP-1_1d_1-25-OH-2D3 347 bp overlap

ChIP THP-1_EtOH_1d GSE89431.VDR.THP-1_EtOH_1d 158 bp overlap

ChIP MCF-7 ENCFF783FFV 131 bp overlap

ZBTB1 2 datasets

ChIP MCF-7 ENCFF466DUW 194 bp overlap

ChIP MCF-7 ENCSR309ELI.ZBTB1.MCF-7 192 bp overlap

ZBTB16 1 dataset

ChIP KG-1_shEZH2 GSE109619.ZBTB16.KG-1_shEZH2 444 bp overlap

ZBTB17 1 dataset

ChIP HEK293 ENCFF865LIO 150 bp overlap

ZNF687 1 dataset

ChIP HepG2 ENCFF653WIX 70 bp overlap