chr1 : 242,585,788 – 242,586,643

855 bp 88 TFs 1 linked gene

This 855 bp open chromatin element is linked to PLD5 and is bound by 88 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
PLD5		61.4 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

88 transcription factors

ARID1A 1 dataset

ChIP HAP1 GSE108387.ARID1A.HAP1 276 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 720 bp overlap

ATF2 1 dataset

ChIP WA01 ENCSR000BQU.ATF2.WA01 134 bp overlap

BCL11A 2 datasets

ChIP H1 ENCFF833IPY 145 bp overlap

ChIP WA01 ENCSR000BIP.BCL11A.WA01 123 bp overlap

BCOR 1 dataset

ChIP WA01 GSE104690.BCOR.WA01 157 bp overlap

CHD2 1 dataset

ChIP H1 ENCFF991MKH 331 bp overlap

CHD7 4 datasets

ChIP H1 ENCFF126NLU 597 bp overlap

ChIP H1 ENCFF126NLU 562 bp overlap

ChIP hiPSC_AF22_abD3F5 GSE108506.CHD7.hiPSC_AF22_abD3F5 403 bp overlap

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 655 bp overlap

CREM 1 dataset

ChIP WTC11 ENCFF209ZUE 481 bp overlap

CTCF 1 dataset

ChIP HAP1_clone21_CTCF-CRISPR GSE152721.CTCF.HAP1_clone21_CTCF-CRISPR 587 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF460KDD 178 bp overlap

ChIP BLaER1 ENCFF460KDD 88 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 251 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 698 bp overlap

EP300 1 dataset

ChIP WA01 ENCSR000BKK.EP300.WA01 187 bp overlap

ETV2::DRGX 1 dataset

Motif ES_0h ES_0h-ETV2DRGX_MA1940.2 12 bp overlap

ETV2::FIGLA 1 dataset

Motif ES_0h ES_0h-ETV2FIGLA_MA1941.2 13 bp overlap

ETV5::DRGX 1 dataset

Motif ES_0h ES_0h-ETV5DRGX_MA1944.2 12 bp overlap

Elf5 1 dataset

Motif ES_0h ES_0h-Elf5_MA0136.4 8 bp overlap

FLI1 1 dataset

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 226 bp overlap

FOXJ2::ELF1 1 dataset

Motif ES_0h ES_0h-FOXJ2ELF1_MA1952.2 11 bp overlap

GLI3 1 dataset

Motif ES_0h ES_0h-GLI3_MA1491.3 15 bp overlap

GLIS2 1 dataset

Motif ES_0h ES_0h-GLIS2_MA0736.1 14 bp overlap

GLIS3 2 datasets

Motif ES_0h ES_0h-GLIS3_MA0737.1 14 bp overlap

ChIP H9_plus GSE109562.GLIS3.H9_plus 855 bp overlap

HDAC2 1 dataset

ChIP H1 ENCFF353UJQ 645 bp overlap

Hmga1 1 dataset

Motif ES_0h ES_0h-Hmga1_MA2124.1 8 bp overlap

IKZF2 1 dataset

Motif ES_0h ES_0h-IKZF2_MA2326.1 6 bp overlap

INSM1 1 dataset

Motif ES_0h ES_0h-INSM1_MA0155.1 12 bp overlap

JUN 3 datasets

ChIP DE_D2 S02-DE-d2-JUN-exp1 510 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 453 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 547 bp overlap

KDM4A 1 dataset

ChIP H1 ENCFF078LED 615 bp overlap

KLF9 1 dataset

Motif ES_0h ES_0h-KLF9_MA1107.3 11 bp overlap

MAX 1 dataset

ChIP WA01 ENCSR000EUP.MAX.WA01 191 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 632 bp overlap

MXI1 1 dataset

Motif ES_0h ES_0h-MXI1_MA1108.3 6 bp overlap

MYBL2 1 dataset

ChIP WTC11 ENCFF166TKT 225 bp overlap

NANOG 11 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 301 bp overlap

ChIP H1 ENCFF747ZPQ 241 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 795 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 558 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 400 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 716 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 626 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 537 bp overlap

ChIP hESC GSE18292.NANOG.hESC 119 bp overlap

ChIP hESC GSE20650.NANOG.hESC 152 bp overlap

NFIA 1 dataset

Motif ES_0h ES_0h-NFIA_MA0670.2 6 bp overlap

NFIC 1 dataset

Motif ES_0h ES_0h-NFIC_MA0161.3 7 bp overlap

NFIX 1 dataset

Motif ES_0h ES_0h-NFIX_MA0671.2 6 bp overlap

NIPBL 1 dataset

ChIP hESC GSE64758.NIPBL.hESC 258 bp overlap

NKX2-2 1 dataset

Motif ES_0h ES_0h-NKX2-2_MA1645.2 8 bp overlap

OTX2 1 dataset

ChIP WTC11 ENCFF634NAO 245 bp overlap

POU2F1 1 dataset

Motif ES_0h ES_0h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 1 dataset

Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 1 dataset

Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap

POU3F1 1 dataset

Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif ES_0h ES_0h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif ES_0h ES_0h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif ES_0h ES_0h-POU3F4_MA0789.1 9 bp overlap

POU4F2 1 dataset

ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 191 bp overlap

POU5F1 10 datasets

ChIP H1 ENCFF698ZAP 205 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 765 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 491 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 828 bp overlap

ChIP WA01 ENCSR000BMU.POU5F1.WA01 179 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 188 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 195 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 286 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 579 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 377 bp overlap

POU5F1B 1 dataset

Motif ES_0h ES_0h-POU5F1B_MA0792.1 9 bp overlap

Plagl1 1 dataset

Motif ES_0h ES_0h-Plagl1_MA1615.2 8 bp overlap

Pou5f1::Sox2 1 dataset

Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap

Prdm4 1 dataset

Motif ES_0h ES_0h-Prdm4_MA1647.3 11 bp overlap

RAD21 2 datasets

ChIP HAP1 GSE152721.RAD21.HAP1 454 bp overlap

ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 621 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 308 bp overlap

REST 2 datasets

Motif ES_0h ES_0h-REST_MA0138.3 20 bp overlap

ChIP neural ENCSR000BTV.REST.neural 135 bp overlap

Rarg 1 dataset

Motif ES_0h ES_0h-Rarg_MA0860.1 17 bp overlap

SMARCA4 3 datasets

ChIP NSC GSE125033.SMARCA4.NSC 537 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 529 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 662 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 321 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 602 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 384 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 540 bp overlap

SOX2 6 datasets

ChIP HNSC GSE69479.SOX2.HNSC 790 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 363 bp overlap

ChIP hiPSC GSE67282.SOX2.hiPSC 420 bp overlap

ChIP hiPSC_INHI GSE67282.SOX2.hiPSC_INHI 203 bp overlap

ChIP hiPSC_KDP53 GSE67282.SOX2.hiPSC_KDP53 492 bp overlap

ChIP hiPSC_KDP53_INHI GSE67282.SOX2.hiPSC_KDP53_INHI 454 bp overlap

SOX21 1 dataset

ChIP neuroepithelilal-cells GSE110505.SOX21.neuroepithelilal-cells 286 bp overlap

SP1 1 dataset

ChIP WA01 ENCSR000BIR.SP1.WA01 151 bp overlap

Stat5b 1 dataset

Motif ES_0h ES_0h-Stat5b_MA1625.2 9 bp overlap

T 2 datasets

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 199 bp overlap

TBX1 1 dataset

Motif ES_0h ES_0h-TBX1_MA0805.1 8 bp overlap

TCF12 2 datasets

ChIP H1 ENCFF203EBH 251 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 137 bp overlap

TEAD1 2 datasets

Motif ES_0h ES_0h-TEAD1_MA0090.4 9 bp overlap

ChIP WTC11 ENCFF502QUV 405 bp overlap

TEAD2 1 dataset

Motif ES_0h ES_0h-TEAD2_MA1121.2 7 bp overlap

TEAD3 1 dataset

Motif ES_0h ES_0h-TEAD3_MA0808.1 8 bp overlap

TEAD4 3 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 295 bp overlap

Motif ES_0h ES_0h-TEAD4_MA0809.3 8 bp overlap

ChIP H1 ENCFF778PAX 245 bp overlap

TFAP2A 1 dataset

Motif ES_0h ES_0h-TFAP2A_MA0872.1 13 bp overlap

TFAP2B 1 dataset

Motif ES_0h ES_0h-TFAP2B_MA0813.1 13 bp overlap

TFAP2C 2 datasets

Motif ES_0h ES_0h-TFAP2C_MA0815.1 13 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 235 bp overlap

TFAP4 1 dataset

Motif ES_0h ES_0h-TFAP4_MA1570.1 10 bp overlap

TFAP4::ETV1 1 dataset

Motif ES_0h ES_0h-TFAP4ETV1_MA1966.2 13 bp overlap

THAP1 1 dataset

Motif ES_0h ES_0h-THAP1_MA0597.3 8 bp overlap

TRIM28 2 datasets

ChIP AF22 GSE84259.TRIM28.AF22 123 bp overlap

ChIP hESC GSE115387.TRIM28.hESC 63 bp overlap

ZNF114 2 datasets

ChIP GM23338 ENCFF631OSW 357 bp overlap

ChIP GM23338 ENCSR555KFE.ZNF114.GM23338 222 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 501 bp overlap

ZNF324 1 dataset

Motif ES_0h ES_0h-ZNF324_MA1977.2 14 bp overlap

ZNF354A 2 datasets

Motif ES_0h ES_0h-ZNF354A_MA1978.2 20 bp overlap

ZNF416 1 dataset

ChIP WTC11 ENCFF407TAZ 271 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 317 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 707 bp overlap

ZNF528 1 dataset

Motif ES_0h ES_0h-ZNF528_MA1597.1 17 bp overlap

ZNF680 2 datasets

Motif ES_0h ES_0h-ZNF680_MA1729.2 11 bp overlap

ZNF708 1 dataset

Motif ES_0h ES_0h-ZNF708_MA1730.2 9 bp overlap

Zic2 1 dataset

Motif ES_0h ES_0h-Zic2_MA1629.2 9 bp overlap