chr1:154,489,011–154,489,730

chr1 : 154,489,011 – 154,489,730

719 bp 82 TFs 9 linked genes

This 719 bp open chromatin element is linked to 9 target genes and is bound by 82 transcription factors.

Linked Genes

9 genes

Gene	Expression	Dist. to TSS	Distance	Link type
SHE		at TSS	At TSS	Proximity
ENSG00000273110		9.0 kb	Proximal	Proximity
UBE2Q1		69.2 kb	Distal	Multiome+HiCAR
ADAR		138.5 kb	Distal	Multiome
ATP8B2		163.9 kb	Distal	Multiome
HAX1		216.8 kb	Distal	Multiome
UBAP2L		268.5 kb	Distal	Multiome
C1orf43		268.8 kb	Distal	Multiome
PMVK		447.3 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

82 transcription factors

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 185 bp overlap

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 246 bp overlap

ChIP MDA-MB-453_FOXA1 ERP003503.AR.MDA-MB-453_FOXA1 153 bp overlap

ARID1B 1 dataset

ChIP K-562 ENCSR822CCM.ARID1B.K-562 201 bp overlap

Motif DE_72h DE_72h-Atf3_MA1988.2 7 bp overlap

Motif DE_72h DE_72h-BATF_MA1634.2 7 bp overlap

BATF3 1 dataset

Motif DE_72h DE_72h-BATF3_MA0835.3 7 bp overlap

BATF::JUN 1 dataset

Motif DE_72h DE_72h-BATFJUN_MA0462.3 7 bp overlap

Motif DE_72h DE_72h-BNC2_MA1928.2 7 bp overlap

BRD4 4 datasets

ChIP COLO-741 GSE73319.BRD4.COLO-741 238 bp overlap

ChIP HEK293_Ctrl GSE129407.BRD4.HEK293_Ctrl 229 bp overlap

ChIP K-562_iBET-BD2 GSE138084.BRD4.K-562_iBET-BD2 234 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD4.K-562_iBET-BD2-IFNG 221 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 252 bp overlap

ChIP K562 ENCFF673OEZ 364 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 225 bp overlap

ChIP hMSC-TERT GSE89179.CHD1.hMSC-TERT 236 bp overlap

ChIP T-47D_ETOH_45 GSE62428.CHD8.T-47D_ETOH_45 102 bp overlap

CTCF 2 datasets

ChIP GM23338 ENCFF772DML 141 bp overlap

ChIP erythroid GSE67783.CTCF.erythroid 223 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF364PUR 155 bp overlap

ChIP BLaER1 ENCFF364PUR 254 bp overlap

ChIP LNCaP_shRB GSE94958.E2F1.LNCaP_shRB 161 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 303 bp overlap

EP300 1 dataset

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 485 bp overlap

ChIP MCF-7 GSE23730.ERG.MCF-7 300 bp overlap

ESR1 8 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 207 bp overlap

ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 237 bp overlap

ChIP MCF-7 GSE48930.ESR1.MCF-7 226 bp overlap

ChIP MCF-7_E2+4OHT_SRC-3 GSE119702.ESR1.MCF-7_E2+4OHT_SRC-3 201 bp overlap

ChIP MCF-7_E2-20min-ERalpha GSE94023.ESR1.MCF-7_E2-20min-ERalpha 105 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 333 bp overlap

ChIP MCF-7_SRC3_OHT GSE119702.ESR1.MCF-7_SRC3_OHT 201 bp overlap

ChIP MCF-7_aldosterone GSE99626.ESR1.MCF-7_aldosterone 188 bp overlap

ChIP TSU-1621MT GSE60477.FLI1.TSU-1621MT 220 bp overlap

FOSL1 1 dataset

Motif DE_72h DE_72h-FOSL1_MA0477.3 9 bp overlap

FOXA1 1 dataset

ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 309 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 586 bp overlap

ChIP DE DE-FOXA2-2 580 bp overlap

GATA1 3 datasets

ChIP K-562 GSE107726.GATA1.K-562 225 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 229 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 243 bp overlap

GATA1::TAL1 2 datasets

Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap

Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap

GATA2 1 dataset

ChIP K-562 ENCSR000DKA.GATA2.K-562 353 bp overlap

GATA3 1 dataset

ChIP T-47D ENCSR000BMX.GATA3.T-47D 144 bp overlap

GATA3_Nter 1 dataset

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 321 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 664 bp overlap

ChIP DE DE-GATA4-2 699 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 348 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 617 bp overlap

ChIP DE DE-GATA6-2 637 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 487 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 525 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 596 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 657 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 637 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 657 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 587 bp overlap

ChIP foregut GSE117136.GATA6.foregut 270 bp overlap

GSPT2 1 dataset

ChIP HEK293T GSE35197.GSPT2.HEK293T 166 bp overlap

GTF2F1 1 dataset

ChIP K-562 ENCSR377BLZ.GTF2F1.K-562 157 bp overlap

HAND2 1 dataset

Motif DE_72h DE_72h-HAND2_MA1638.2 6 bp overlap

HNRNPLL 1 dataset

ChIP Hep-G2 ENCSR804HMZ.HNRNPLL.Hep-G2 148 bp overlap

ChIP K-562 ENCSR854MCV.IRF1.K-562 304 bp overlap

JUN::JUNB 1 dataset

Motif DE_72h DE_72h-JUNJUNB_MA1132.2 8 bp overlap

Motif DE_72h DE_72h-JUNB_MA0490.3 9 bp overlap

Motif DE_72h DE_72h-Jun_MA0489.3 8 bp overlap

ChIP HEK293_E419Q GSE88976.KLF5.HEK293_E419Q 223 bp overlap

ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 210 bp overlap

Motif DE_72h DE_72h-MAFK_MA0496.4 10 bp overlap

MED1 3 datasets

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 312 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 703 bp overlap

ChIP MM1-S_JQ1_5000NM GSE49224.MED1.MM1-S_JQ1_5000NM 175 bp overlap

ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 229 bp overlap

NCAPH2 1 dataset

ChIP HEK293 GSE97540.NCAPH2.HEK293 222 bp overlap

NEUROG2 1 dataset

Motif DE_72h DE_72h-NEUROG2_MA1642.2 7 bp overlap

NFKBIA 1 dataset

ChIP dermal GSE30082.NFKBIA.dermal 275 bp overlap

NKX6-3 1 dataset

Motif DE_72h DE_72h-NKX6-3_MA1530.2 8 bp overlap

OGG1 3 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 355 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 293 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 311 bp overlap

PHF19 1 dataset

ChIP DU145_SH4 GSE135623.PHF19.DU145_SH4 312 bp overlap

POLR2A 2 datasets

ChIP spleen ENCFF446ZGT 284 bp overlap

ChIP spleen ENCFF706IUS 271 bp overlap

RBM39 1 dataset

ChIP Hep-G2 GSE120104.RBM39.Hep-G2 216 bp overlap

ChIP A-549 ENCSR798EGJ.RNF2.A-549 236 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 193 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 243 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 328 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 719 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 682 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 486 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 404 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 672 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 300 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 694 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 663 bp overlap

SMAD3 1 dataset

ChIP endoderm GSE29422.SMAD3.endoderm 262 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 258 bp overlap

SMARCA4 1 dataset

ChIP MCF-10A GSE74716.SMARCA4.MCF-10A 188 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 504 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 705 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 233 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 222 bp overlap

SRSF3 1 dataset

ChIP K-562 ENCSR268QIQ.SRSF3.K-562 172 bp overlap

STAT3 3 datasets

ChIP MCF-7_jc5838 GSE126004.STAT3.MCF-7_jc5838 221 bp overlap

ChIP MDA-MB-453 GSE152203.STAT3.MDA-MB-453 174 bp overlap

ChIP WA01 ERP004237.STAT3.WA01 224 bp overlap

SUZ12 2 datasets

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 653 bp overlap

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 329 bp overlap

TAF15 1 dataset

ChIP Hep-G2 ENCSR825MZS.TAF15.Hep-G2 163 bp overlap

TAL1 3 datasets

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 216 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 241 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 149 bp overlap

TBL1X 1 dataset

ChIP HEK293T GSE35197.TBL1X.HEK293T 189 bp overlap

TBX18 1 dataset

Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 170 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 218 bp overlap

ChIP K-562 ENCSR000EFZ.UBTF.K-562 103 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 298 bp overlap

ZBTB33 2 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 308 bp overlap

ChIP K562 ENCFF875HLX 188 bp overlap

ZBTB40 1 dataset

ChIP K562 ENCFF337GJB 96 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 292 bp overlap

ZFP42 1 dataset

Motif DE_48h DE_48h-ZFP42_MA1651.2 13 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 362 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 220 bp overlap

ZNF354C 1 dataset

Motif DE_72h DE_72h-ZNF354C_MA0130.1 6 bp overlap

ZNF711 1 dataset

ChIP HEK293T GSE145160.ZNF711.HEK293T 228 bp overlap

ZNF85 1 dataset

Motif DE_72h DE_72h-ZNF85_MA1720.2 12 bp overlap