chr1:99,950,389–99,951,124

chr1 : 99,950,389 – 99,951,124

735 bp 109 TFs 8 linked genes

This 735 bp open chromatin element is linked to 8 target genes and is bound by 109 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000228084		19.3 kb	Distal	Multiome
SLC35A3		19.4 kb	Distal	Multiome
MFSD14A		87.5 kb	Distal	Multiome
AGL		100.3 kb	Distal	Multiome
SASS6		182.3 kb	Distal	Multiome
TRMT13		182.5 kb	Distal	Multiome
FRRS1		184.0 kb	Distal	Multiome
DBT		299.2 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

109 transcription factors

ChIP VCaP_DHAT_2H GSE28950.AR.VCaP_DHAT_2H 80 bp overlap

ChIP VCaP_Darolutamide GSE148358.AR.VCaP_Darolutamide 55 bp overlap

ChIP VCaP_R1881 GSE32892.AR.VCaP_R1881 69 bp overlap

ChIP prostate-cancer_PDX_167 GSE130408.AR.prostate-cancer_PDX_167 110 bp overlap

ATOH7 1 dataset

Motif DE_48h DE_48h-ATOH7_MA1468.1 10 bp overlap

Atoh1 1 dataset

Motif DE_48h DE_48h-Atoh1_MA0461.3 8 bp overlap

BHLHA15 1 dataset

Motif DE_48h DE_48h-BHLHA15_MA0607.2 10 bp overlap

BHLHE22 1 dataset

Motif DE_48h DE_48h-BHLHE22_MA0818.2 10 bp overlap

BHLHE23 1 dataset

Motif DE_48h DE_48h-BHLHE23_MA0817.2 10 bp overlap

ChIP H-1_DE GSE126661.BRD3.H-1_DE 601 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 289 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 322 bp overlap

ERF::FOXO1 1 dataset

Motif DE_48h DE_48h-ERFFOXO1_MA1936.2 12 bp overlap

ETS1 2 datasets

ChIP CTV-1_DSG GSE128835.ETS1.CTV-1_DSG 357 bp overlap

ChIP CTV-1_DSG_SPI1-mut GSE128835.ETS1.CTV-1_DSG_SPI1-mut 336 bp overlap

ETV2::HOXB13 1 dataset

Motif DE_48h DE_48h-ETV2HOXB13_MA1943.2 13 bp overlap

ETV5::FOXI1 2 datasets

Motif DE_48h DE_48h-ETV5FOXI1_MA1946.2 12 bp overlap

Motif DE_48h DE_48h-ETV5FOXI1_MA1946.2 12 bp overlap

ETV5::FOXO1 1 dataset

Motif DE_48h DE_48h-ETV5FOXO1_MA1947.2 10 bp overlap

FIGLA 1 dataset

Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap

FLI1::FOXI1 1 dataset

Motif DE_48h DE_48h-FLI1FOXI1_MA1950.2 11 bp overlap

FOXA1 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 391 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 584 bp overlap

ChIP DE DE-FOXA2-2 531 bp overlap

FOXB1 1 dataset

Motif DE_48h DE_48h-FOXB1_MA0845.1 11 bp overlap

FOXC1 1 dataset

Motif DE_48h DE_48h-FOXC1_MA0032.2 11 bp overlap

FOXC2 1 dataset

Motif DE_48h DE_48h-FOXC2_MA0846.2 11 bp overlap

FOXD3 1 dataset

Motif DE_48h DE_48h-FOXD3_MA0041.3 14 bp overlap

FOXO1::ELF1 1 dataset

Motif DE_48h DE_48h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXO1::ELK1 1 dataset

Motif DE_48h DE_48h-FOXO1ELK1_MA1954.2 13 bp overlap

FOXO1::ELK3 1 dataset

Motif DE_48h DE_48h-FOXO1ELK3_MA1955.2 13 bp overlap

GATA1::TAL1 1 dataset

Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap

GATA2 2 datasets

Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap

ChIP SKH1 GSE87283.GATA2.SKH1 175 bp overlap

GATA4 8 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 119 bp overlap

ChIP DE DE-GATA4-1 735 bp overlap

ChIP DE DE-GATA4-2 735 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 104 bp overlap

ChIP foregut GSE117136.GATA4.foregut 307 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 386 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 535 bp overlap

GATA5 1 dataset

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

GATA6 13 datasets

ChIP DE DE-GATA6-1 598 bp overlap

ChIP DE DE-GATA6-2 647 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 418 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 333 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 735 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 326 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 381 bp overlap

ChIP foregut GSE117136.GATA6.foregut 381 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 267 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 320 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 264 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 524 bp overlap

GLIS1 1 dataset

Motif DE_48h DE_48h-GLIS1_MA0735.2 15 bp overlap

Gata3 1 dataset

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

HNF1A 1 dataset

Motif DE_48h DE_48h-HNF1A_MA0046.3 13 bp overlap

HNF1B 1 dataset

Motif DE_48h DE_48h-HNF1B_MA0153.2 13 bp overlap

HNF4A 1 dataset

Motif DE_48h DE_48h-HNF4A_MA0114.5 9 bp overlap

HNF4G 1 dataset

Motif DE_48h DE_48h-HNF4G_MA0484.3 9 bp overlap

HOXB13 1 dataset

ChIP prostate-cancer_PDX_167 GSE130408.HOXB13.prostate-cancer_PDX_167 70 bp overlap

Hnf1A 1 dataset

Motif DE_48h DE_48h-Hnf1A_MA1991.2 10 bp overlap

INSM1 1 dataset

Motif DE_48h DE_48h-INSM1_MA0155.1 12 bp overlap

ChIP 786-O GSE86092.JUN.786-O 218 bp overlap

MEIS1 1 dataset

Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap

ChIP DU528 GSE94000.MYB.DU528 528 bp overlap

Motif DE_48h DE_48h-MYF6_MA0667.1 10 bp overlap

Motif DE_48h DE_48h-Mafb_MA0117.3 11 bp overlap

NEUROG1 1 dataset

Motif DE_48h DE_48h-NEUROG1_MA0623.2 10 bp overlap

NEUROG2 1 dataset

Motif DE_48h DE_48h-NEUROG2_MA0669.1 10 bp overlap

NFATC3 1 dataset

Motif DE_48h DE_48h-NFATC3_MA0625.3 6 bp overlap

NFATC4 1 dataset

Motif DE_48h DE_48h-NFATC4_MA1525.3 9 bp overlap

NR5A1 1 dataset

Motif DE_48h DE_48h-NR5A1_MA1540.3 12 bp overlap

Motif DE_48h DE_48h-NRL_MA0842.3 12 bp overlap

Nfatc1 1 dataset

Motif DE_48h DE_48h-Nfatc1_MA0624.3 6 bp overlap

Nfatc2 1 dataset

Motif DE_48h DE_48h-Nfatc2_MA0152.3 8 bp overlap

Nr5A2 1 dataset

Motif DE_48h DE_48h-Nr5A2_MA0505.3 9 bp overlap

OLIG1 1 dataset

Motif DE_48h DE_48h-OLIG1_MA0826.1 10 bp overlap

OLIG2 1 dataset

Motif DE_48h DE_48h-OLIG2_MA0678.1 10 bp overlap

OLIG3 1 dataset

Motif DE_48h DE_48h-OLIG3_MA0827.1 10 bp overlap

Motif DE_48h DE_48h-PBX2_MA1113.3 9 bp overlap

POU3F1 1 dataset

Motif DE_48h DE_48h-POU3F1_MA0786.2 10 bp overlap

POU4F2 1 dataset

Motif DE_48h DE_48h-POU4F2_MA0683.2 15 bp overlap

PRDM9 2 datasets

Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap

Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap

Pparg::Rxra 1 dataset

Motif DE_48h DE_48h-PpargRxra_MA0065.3 13 bp overlap

Prdm5 1 dataset

Motif DE_48h DE_48h-Prdm5_MA1999.2 11 bp overlap

Ptf1A 2 datasets

Motif DE_48h DE_48h-Ptf1A_MA1618.2 9 bp overlap

Motif DE_48h DE_48h-Ptf1A_MA1620.2 8 bp overlap

Motif DE_48h DE_48h-REST_MA0138.3 20 bp overlap

Motif DE_48h DE_48h-SIX1_MA1118.2 9 bp overlap

Motif DE_48h DE_48h-SIX2_MA1119.2 11 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 521 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 679 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 690 bp overlap

SMARCA4 6 datasets

ChIP CTV-1_DSG GSE128835.SMARCA4.CTV-1_DSG 600 bp overlap

ChIP CTV-1_DSG_SPI1-mut GSE128835.SMARCA4.CTV-1_DSG_SPI1-mut 599 bp overlap

ChIP CTV-1_FLAG GSE128835.SMARCA4.CTV-1_FLAG 393 bp overlap

ChIP CTV-1_FLAG_SPI1-mut GSE128835.SMARCA4.CTV-1_FLAG_SPI1-mut 604 bp overlap

ChIP CTV-1_delA GSE128835.SMARCA4.CTV-1_delA 565 bp overlap

ChIP CTV-1_delQ GSE128835.SMARCA4.CTV-1_delQ 474 bp overlap

SOX10 1 dataset

Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 408 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 517 bp overlap

Motif DE_48h DE_48h-SOX4_MA0867.3 8 bp overlap

SPI1 3 datasets

ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 276 bp overlap

ChIP CTV-1_delA GSE128835.SPI1.CTV-1_delA 190 bp overlap

ChIP CTV-1_delQ GSE128835.SPI1.CTV-1_delQ 344 bp overlap

Motif DE_48h DE_48h-SPIB_MA0081.3 13 bp overlap

Motif DE_48h DE_48h-Six4_MA2001.2 7 bp overlap

Sox11 1 dataset

Motif DE_48h DE_48h-Sox11_MA0869.3 8 bp overlap

Sox17 1 dataset

Motif DE_48h DE_48h-Sox17_MA0078.3 10 bp overlap

Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap

Motif DE_48h DE_48h-Sox7_MA2095.1 10 bp overlap

Stat2 1 dataset

Motif DE_48h DE_48h-Stat2_MA1623.2 10 bp overlap

Stat5b 1 dataset

Motif DE_48h DE_48h-Stat5b_MA1625.2 9 bp overlap

Stat6 1 dataset

Motif DE_48h DE_48h-Stat6_MA0520.2 10 bp overlap

TAL1::TCF3 1 dataset

Motif DE_48h DE_48h-TAL1TCF3_MA0091.2 10 bp overlap

Motif DE_48h DE_48h-TBP_MA0108.3 7 bp overlap

TCF21 1 dataset

Motif DE_48h DE_48h-TCF21_MA1568.2 10 bp overlap

ChIP CAL-1 GSE76147.TCF4.CAL-1 171 bp overlap

TCF7L2 1 dataset

Motif DE_48h DE_48h-TCF7L2_MA0523.2 9 bp overlap

TFAP2E 1 dataset

Motif DE_48h DE_48h-TFAP2E_MA1569.2 9 bp overlap

TFAP4 1 dataset

Motif DE_48h DE_48h-TFAP4_MA1570.1 10 bp overlap

TRPS1 1 dataset

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

ZBTB24 1 dataset

Motif DE_48h DE_48h-ZBTB24_MA2330.1 10 bp overlap

Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap

ZNF148 1 dataset

Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap

ZNF213 1 dataset

Motif DE_48h DE_48h-ZNF213_MA2121.1 12 bp overlap

ZNF281 1 dataset

Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap

ZNF320 1 dataset

Motif DE_48h DE_48h-ZNF320_MA1976.2 20 bp overlap

ZNF343 1 dataset

Motif DE_48h DE_48h-ZNF343_MA1711.2 16 bp overlap

ZNF354A 1 dataset

Motif DE_48h DE_48h-ZNF354A_MA1978.2 20 bp overlap

ZNF384 1 dataset

Motif DE_48h DE_48h-ZNF384_MA1125.2 8 bp overlap

ZNF416 1 dataset

Motif DE_48h DE_48h-ZNF416_MA1979.2 10 bp overlap

ZNF418 1 dataset

Motif DE_48h DE_48h-ZNF418_MA1980.1 15 bp overlap

ZNF549 1 dataset

Motif DE_48h DE_48h-ZNF549_MA1728.2 8 bp overlap

ZNF558 1 dataset

Motif DE_48h DE_48h-ZNF558_MA2335.1 29 bp overlap

ZNF677 1 dataset

Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap

ZNF680 1 dataset

Motif DE_48h DE_48h-ZNF680_MA1729.2 11 bp overlap

Zic1::Zic2 1 dataset

Motif DE_48h DE_48h-Zic1Zic2_MA1628.2 7 bp overlap

Motif DE_48h DE_48h-Zic2_MA1629.2 9 bp overlap

Motif DE_48h DE_48h-Zic3_MA0697.3 7 bp overlap