chr5 : 5,198,807 – 5,199,844
1,037 bp 128 TFs 3 linked genes
This 1.0 kb open chromatin element is linked to ADAMTS16, ADAMTS16-DT, and ICE1 and is bound by 128 transcription factors.
Linked Genes
3 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ADAMTS16 58.9 kb Distal Multiome
ADAMTS16-DT 59.1 kb Distal Multiome
ICE1 223.5 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr5:5,193,807 – 5,204,844
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
128 transcription factors
Source
Cell type
ARNTL 1 dataset
ChIP U2OS_trough_DMOG GSE85096.ARNTL.U2OS_trough_DMOG 229 bp overlap
Alx4 1 dataset
Motif DE_48h DE_48h-Alx4_MA0853.2 12 bp overlap
Ar 2 datasets
Motif DE_36h DE_36h-Ar_MA0007.4 16 bp overlap
Motif DE_48h DE_48h-Ar_MA0007.4 16 bp overlap
Arx 1 dataset
Motif DE_48h DE_48h-Arx_MA0874.2 10 bp overlap
BARX1 1 dataset
Motif DE_48h DE_48h-BARX1_MA0875.2 6 bp overlap
BCL6B 1 dataset
Motif DE_48h DE_48h-BCL6B_MA0731.1 17 bp overlap
BCOR 1 dataset
ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 224 bp overlap
BRD3 1 dataset
ChIP H-1_DE GSE126661.BRD3.H-1_DE 213 bp overlap
BSX 1 dataset
Motif DE_48h DE_48h-BSX_MA0876.2 6 bp overlap
CDK6 1 dataset
ChIP KB_IL GSE52469.CDK6.KB_IL 113 bp overlap
DLX1 1 dataset
Motif DE_48h DE_48h-DLX1_MA0879.3 6 bp overlap
DLX6 1 dataset
Motif DE_48h DE_48h-DLX6_MA0882.2 6 bp overlap
Dlx3 1 dataset
Motif DE_48h DE_48h-Dlx3_MA0880.2 6 bp overlap
Dlx4 1 dataset
Motif DE_48h DE_48h-Dlx4_MA0881.2 6 bp overlap
EBF3 2 datasets
Motif DE_36h DE_36h-EBF3_MA1637.2 9 bp overlap
Motif DE_48h DE_48h-EBF3_MA1637.2 9 bp overlap
EHF 2 datasets
Motif DE_36h DE_36h-EHF_MA0598.4 9 bp overlap
Motif DE_48h DE_48h-EHF_MA0598.4 9 bp overlap
ELF1 2 datasets
Motif DE_36h DE_36h-ELF1_MA0473.4 9 bp overlap
Motif DE_48h DE_48h-ELF1_MA0473.4 9 bp overlap
ELF3 2 datasets
Motif DE_36h DE_36h-ELF3_MA0640.3 9 bp overlap
Motif DE_48h DE_48h-ELF3_MA0640.3 9 bp overlap
EN2 1 dataset
Motif DE_48h DE_48h-EN2_MA0642.3 7 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 555 bp overlap
ETS1 1 dataset
ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 258 bp overlap
EZH2 1 dataset
ChIP LNCaP GSE39459.EZH2.LNCaP 238 bp overlap
Ebf2 2 datasets
Motif DE_36h DE_36h-Ebf2_MA1604.2 9 bp overlap
Motif DE_48h DE_48h-Ebf2_MA1604.2 9 bp overlap
Elf5 2 datasets
Motif DE_36h DE_36h-Elf5_MA0136.4 8 bp overlap
Motif DE_48h DE_48h-Elf5_MA0136.4 8 bp overlap
FOXA2 6 datasets
ChIP DE DE-FOXA2-1 386 bp overlap
ChIP DE DE-FOXA2-1 287 bp overlap
ChIP DE DE-FOXA2-2 309 bp overlap
ChIP DE DE-FOXA2-2 355 bp overlap
Motif DE_36h DE_36h-FOXA2_MA0047.4 8 bp overlap
Motif DE_48h DE_48h-FOXA2_MA0047.4 8 bp overlap
FOXA3 2 datasets
Motif DE_36h DE_36h-FOXA3_MA1683.2 7 bp overlap
Motif DE_48h DE_48h-FOXA3_MA1683.2 7 bp overlap
FOXB1 2 datasets
Motif DE_36h DE_36h-FOXB1_MA0845.1 11 bp overlap
Motif DE_48h DE_48h-FOXB1_MA0845.1 11 bp overlap
FOXC1 2 datasets
Motif DE_36h DE_36h-FOXC1_MA0032.2 11 bp overlap
Motif DE_48h DE_48h-FOXC1_MA0032.2 11 bp overlap
FOXC2 2 datasets
Motif DE_36h DE_36h-FOXC2_MA0846.2 11 bp overlap
Motif DE_48h DE_48h-FOXC2_MA0846.2 11 bp overlap
FOXD2 2 datasets
Motif DE_36h DE_36h-FOXD2_MA0847.4 11 bp overlap
Motif DE_48h DE_48h-FOXD2_MA0847.4 11 bp overlap
FOXD3 3 datasets
Motif DE_36h DE_36h-FOXD3_MA0041.3 14 bp overlap
Motif DE_48h DE_48h-FOXD3_MA0041.3 14 bp overlap
Motif DE_48h DE_48h-FOXD3_MA0041.3 14 bp overlap
FOXF2 2 datasets
Motif DE_36h DE_36h-FOXF2_MA0030.2 9 bp overlap
Motif DE_48h DE_48h-FOXF2_MA0030.2 9 bp overlap
FOXI1 2 datasets
Motif DE_36h DE_36h-FOXI1_MA0042.2 7 bp overlap
Motif DE_48h DE_48h-FOXI1_MA0042.2 7 bp overlap
FOXO1::FLI1 2 datasets
Motif DE_36h DE_36h-FOXO1FLI1_MA1956.2 13 bp overlap
Motif DE_48h DE_48h-FOXO1FLI1_MA1956.2 13 bp overlap
FOXP1 2 datasets
Motif DE_36h DE_36h-FOXP1_MA0481.4 7 bp overlap
Motif DE_48h DE_48h-FOXP1_MA0481.4 7 bp overlap
FOXP4 2 datasets
Motif DE_36h DE_36h-FOXP4_MA2117.1 7 bp overlap
Motif DE_48h DE_48h-FOXP4_MA2117.1 7 bp overlap
Foxj3 2 datasets
Motif DE_36h DE_36h-Foxj3_MA0851.2 9 bp overlap
Motif DE_48h DE_48h-Foxj3_MA0851.2 9 bp overlap
Foxl2 2 datasets
Motif DE_36h DE_36h-Foxl2_MA1607.2 10 bp overlap
Motif DE_48h DE_48h-Foxl2_MA1607.2 10 bp overlap
GATA6 3 datasets
ChIP DE_D1 S41-DE-d1-GATA6-exp2 420 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 352 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 313 bp overlap
GBX1 1 dataset
Motif DE_48h DE_48h-GBX1_MA0889.2 7 bp overlap
GBX2 1 dataset
Motif DE_48h DE_48h-GBX2_MA0890.2 6 bp overlap
HESX1 1 dataset
Motif DE_48h DE_48h-HESX1_MA0894.2 6 bp overlap
HIF1A 2 datasets
ChIP U2OS_trough_DMOG GSE85096.HIF1A.U2OS_trough_DMOG 257 bp overlap
ChIP U2OS_trough_DMOG GSE85096.HIF1A.U2OS_trough_DMOG 414 bp overlap
HOXA7 1 dataset
Motif DE_48h DE_48h-HOXA7_MA1498.3 6 bp overlap
HOXB4 2 datasets
Motif DE_36h DE_36h-HOXB4_MA1499.2 6 bp overlap
Motif DE_48h DE_48h-HOXB4_MA1499.2 6 bp overlap
HOXC4 2 datasets
Motif DE_36h DE_36h-HOXC4_MA1504.2 6 bp overlap
Motif DE_48h DE_48h-HOXC4_MA1504.2 6 bp overlap
HOXD4 2 datasets
Motif DE_36h DE_36h-HOXD4_MA1507.2 6 bp overlap
Motif DE_48h DE_48h-HOXD4_MA1507.2 6 bp overlap
Hand1::Tcf3 1 dataset
Motif DE_48h DE_48h-Hand1Tcf3_MA0092.2 9 bp overlap
Hmx1 1 dataset
Motif DE_48h DE_48h-Hmx1_MA0896.2 9 bp overlap
Hmx3 1 dataset
Motif DE_48h DE_48h-Hmx3_MA0898.2 9 bp overlap
IKZF2 2 datasets
Motif DE_36h DE_36h-IKZF2_MA2326.1 6 bp overlap
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
Isl1 2 datasets
Motif DE_48h DE_48h-Isl1_MA1608.2 7 bp overlap
Motif DE_48h DE_48h-Isl1_MA1608.2 7 bp overlap
JUN 3 datasets
Motif DE_36h DE_36h-JUN_MA0488.2 10 bp overlap
Motif DE_48h DE_48h-JUN_MA0488.2 10 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 310 bp overlap
JUND 2 datasets
Motif DE_36h DE_36h-JUND_MA0492.2 11 bp overlap
Motif DE_48h DE_48h-JUND_MA0492.2 11 bp overlap
KDM5B 1 dataset
ChIP HCC2157 GSE46055.KDM5B.HCC2157 143 bp overlap
LBX1 1 dataset
Motif DE_48h DE_48h-LBX1_MA0618.2 7 bp overlap
LBX2 1 dataset
Motif DE_48h DE_48h-LBX2_MA0699.2 6 bp overlap
LHX2 1 dataset
Motif DE_48h DE_48h-LHX2_MA0700.3 6 bp overlap
LHX9 1 dataset
Motif DE_48h DE_48h-LHX9_MA0701.3 7 bp overlap
Lhx1 1 dataset
Motif DE_48h DE_48h-Lhx1_MA1518.3 10 bp overlap
MAX 1 dataset
ChIP NCI-H128 GSE41105.MAX.NCI-H128 524 bp overlap
MGA::EVX1 1 dataset
Motif DE_48h DE_48h-MGAEVX1_MA1960.2 11 bp overlap
MSX1 1 dataset
Motif DE_48h DE_48h-MSX1_MA0666.3 6 bp overlap
MSX2 1 dataset
Motif DE_48h DE_48h-MSX2_MA0708.3 6 bp overlap
MXI1 1 dataset
Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap
Msx3 1 dataset
Motif DE_48h DE_48h-Msx3_MA0709.2 6 bp overlap
NANOG 10 datasets
ChIP H1 ENCFF747ZPQ 241 bp overlap
ChIP HUES-8 GSE109524.NANOG.HUES-8 368 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 342 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 283 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 658 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 251 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 218 bp overlap
ChIP hESC GSE18292.NANOG.hESC 93 bp overlap
ChIP hESC GSE20650.NANOG.hESC 203 bp overlap
ChIP hESC GSE18292.NANOG.hESC 55 bp overlap
NEUROG2 1 dataset
ChIP MRC-5_N_05DPT GSE75910.NEUROG2.MRC-5_N_05DPT 292 bp overlap
NFIA 1 dataset
Motif DE_48h DE_48h-NFIA_MA0670.2 6 bp overlap
NFIB 2 datasets
Motif DE_48h DE_48h-NFIB_MA1643.2 17 bp overlap
ChIP MCF-7 ENCSR582ZOA.NFIB.MCF-7 265 bp overlap
NFIC 1 dataset
Motif DE_48h DE_48h-NFIC_MA1527.2 15 bp overlap
NFIC::TLX1 1 dataset
Motif DE_48h DE_48h-NFICTLX1_MA0119.1 14 bp overlap
NFIX 2 datasets
Motif DE_48h DE_48h-NFIX_MA0671.2 6 bp overlap
Motif DE_48h DE_48h-NFIX_MA1528.2 14 bp overlap
NKX2-2 2 datasets
Motif DE_36h DE_36h-NKX2-2_MA1645.2 8 bp overlap
Motif DE_48h DE_48h-NKX2-2_MA1645.2 8 bp overlap
NKX2-5 2 datasets
Motif DE_36h DE_36h-NKX2-5_MA0063.3 7 bp overlap
Motif DE_48h DE_48h-NKX2-5_MA0063.3 7 bp overlap
NKX6-1 2 datasets
Motif DE_36h DE_36h-NKX6-1_MA0674.2 7 bp overlap
Motif DE_48h DE_48h-NKX6-1_MA0674.2 7 bp overlap
NKX6-3 4 datasets
Motif DE_36h DE_36h-NKX6-3_MA1530.2 8 bp overlap
Motif DE_48h DE_48h-NKX6-3_MA1530.2 8 bp overlap
Motif DE_48h DE_48h-NKX6-3_MA1530.2 8 bp overlap
Motif DE_48h DE_48h-NKX6-3_MA1530.2 8 bp overlap
NR3C1 2 datasets
Motif DE_36h DE_36h-NR3C1_MA0113.4 15 bp overlap
Motif DE_48h DE_48h-NR3C1_MA0113.4 15 bp overlap
NR3C2 2 datasets
Motif DE_36h DE_36h-NR3C2_MA0727.2 15 bp overlap
Motif DE_48h DE_48h-NR3C2_MA0727.2 15 bp overlap
Nobox 1 dataset
Motif DE_48h DE_48h-Nobox_MA0125.2 6 bp overlap
Nr5A2 2 datasets
Motif DE_36h DE_36h-Nr5A2_MA0505.3 9 bp overlap
Motif DE_48h DE_48h-Nr5A2_MA0505.3 9 bp overlap
PAX5 1 dataset
ChIP fetal_testis GSE100639.PAX5.fetal_testis 165 bp overlap
PLAG1 1 dataset
Motif DE_48h DE_48h-PLAG1_MA0163.1 14 bp overlap
POU5F1 2 datasets
ChIP HUES-8 GSE109524.POU5F1.HUES-8 261 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 395 bp overlap
POU6F1 2 datasets
Motif DE_36h DE_36h-POU6F1_MA1549.2 7 bp overlap
Motif DE_48h DE_48h-POU6F1_MA1549.2 7 bp overlap
PRDM1 1 dataset
ChIP fetal_testis GSE100639.PRDM1.fetal_testis 168 bp overlap
PRDM9 2 datasets
Motif DE_36h DE_36h-PRDM9_MA1723.2 20 bp overlap
Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap
PRRX2 1 dataset
Motif DE_48h DE_48h-PRRX2_MA0075.4 7 bp overlap
Pgr 2 datasets
Motif DE_36h DE_36h-Pgr_MA2323.1 17 bp overlap
Motif DE_48h DE_48h-Pgr_MA2323.1 17 bp overlap
Plagl1 1 dataset
Motif DE_48h DE_48h-Plagl1_MA1615.2 8 bp overlap
RAX 1 dataset
Motif DE_48h DE_48h-RAX_MA0718.2 6 bp overlap
RBPJ 1 dataset
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
SIX2 3 datasets
ChIP HEK GSE73865.SIX2.HEK 346 bp overlap
ChIP kidney_fetal_16w GSE75948.SIX2.kidney_fetal_16w 245 bp overlap
ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 370 bp overlap
SMAD2 2 datasets
Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap
ChIP endoderm GSE29422.SMAD2.endoderm 233 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 359 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 894 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 835 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 412 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 253 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 508 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 362 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 328 bp overlap
SMAD3 2 datasets
ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 181 bp overlap
ChIP hESC GSE29422.SMAD3.hESC 174 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 184 bp overlap
SMARCA4 2 datasets
ChIP 501-mel_SHSOX10 GSE61965.SMARCA4.501-mel_SHSOX10 276 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 317 bp overlap
SMARCB1 1 dataset
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 216 bp overlap
SMARCC1 2 datasets
ChIP hiPSC GSE124903.SMARCC1.hiPSC 166 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 269 bp overlap
SMC3 1 dataset
ChIP HeLa-Kyoto_PDS5-depleted GSE102884.SMC3.HeLa-Kyoto_PDS5-depleted 194 bp overlap
SNAI2 1 dataset
ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 174 bp overlap
SOX11 1 dataset
ChIP GRANT-A519 GSE52146.SOX11.GRANT-A519 90 bp overlap
SOX13 1 dataset
Motif DE_48h DE_48h-SOX13_MA1120.2 7 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 513 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 839 bp overlap
SOX2 1 dataset
Motif DE_48h DE_48h-SOX2_MA0143.5 7 bp overlap
SOX9 1 dataset
Motif DE_48h DE_48h-SOX9_MA0077.2 8 bp overlap
SPIB 2 datasets
Motif DE_36h DE_36h-SPIB_MA0081.3 13 bp overlap
Motif DE_48h DE_48h-SPIB_MA0081.3 13 bp overlap
Sox3 1 dataset
Motif DE_48h DE_48h-Sox3_MA0514.3 7 bp overlap
Spi1 2 datasets
Motif DE_36h DE_36h-Spi1_MA0080.7 13 bp overlap
Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap
Stat5a::Stat5b 1 dataset
Motif DE_48h DE_48h-Stat5aStat5b_MA0519.2 9 bp overlap
Stat5b 3 datasets
Motif DE_36h DE_36h-Stat5b_MA1625.2 9 bp overlap
Motif DE_48h DE_48h-Stat5b_MA1625.2 9 bp overlap
Motif DE_48h DE_48h-Stat5b_MA1625.2 9 bp overlap
T 2 datasets
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 429 bp overlap
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap
TP53 1 dataset
ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 204 bp overlap
Yy1 2 datasets
Motif DE_36h DE_36h-Yy1_MA0095.4 8 bp overlap
Motif DE_48h DE_48h-Yy1_MA0095.4 8 bp overlap
ZFP14 2 datasets
Motif DE_36h DE_36h-ZFP14_MA1972.1 15 bp overlap
Motif DE_48h DE_48h-ZFP14_MA1972.1 15 bp overlap
ZNF331 2 datasets
Motif DE_36h DE_36h-ZNF331_MA1726.2 10 bp overlap
Motif DE_48h DE_48h-ZNF331_MA1726.2 10 bp overlap
ZNF354A 2 datasets
Motif DE_36h DE_36h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_48h DE_48h-ZNF354A_MA1978.2 20 bp overlap
ZNF410 2 datasets
Motif DE_36h DE_36h-ZNF410_MA0752.2 16 bp overlap
Motif DE_48h DE_48h-ZNF410_MA0752.2 16 bp overlap
ZNF423 1 dataset
ChIP WTC11 ENCFF574PBR 228 bp overlap
ZNF462 2 datasets
ChIP GM23338 ENCFF896CCA 251 bp overlap
ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 320 bp overlap
ZNF558 1 dataset
Motif DE_48h DE_48h-ZNF558_MA2335.1 29 bp overlap
ZNF680 2 datasets
Motif DE_36h DE_36h-ZNF680_MA1729.2 11 bp overlap
Motif DE_48h DE_48h-ZNF680_MA1729.2 11 bp overlap
ZNF8 2 datasets
Motif DE_36h DE_36h-ZNF8_MA1718.1 20 bp overlap
Motif DE_48h DE_48h-ZNF8_MA1718.1 20 bp overlap
Zfp809 2 datasets
Motif DE_36h DE_36h-Zfp809_MA2125.1 9 bp overlap
Motif DE_48h DE_48h-Zfp809_MA2125.1 9 bp overlap
Zfp961 1 dataset
Motif DE_48h DE_48h-Zfp961_MA2126.1 8 bp overlap
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