chr5:1,827,805–1,828,459

chr5 : 1,827,805 – 1,828,459

654 bp 84 TFs 6 linked genes

This 654 bp open chromatin element is linked to 6 target genes and is bound by 84 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
NDUFS6		26.8 kb	Distal	Multiome
MRPL36		28.3 kb	Distal	Multiome
IRX4		54.6 kb	Distal	Multiome
ENSG00000248994		102.9 kb	Distal	Multiome
ENSG00000291079		194.2 kb	Distal	Multiome
ENSG00000291055		233.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

84 transcription factors

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 349 bp overlap

BACH1 1 dataset

ChIP WA01 ENCSR000EBQ.BACH1.WA01 157 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 234 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 199 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 150 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 609 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 224 bp overlap

CTCF 3 datasets

ChIP pancreas_body ENCSR408XTO.CTCF.pancreas_body 240 bp overlap

ChIP pancreas_body ENCSR265PFQ.CTCF.pancreas_body 203 bp overlap

ChIP pancreas_body ENCSR484DDO.CTCF.pancreas_body 150 bp overlap

CTCFL 1 dataset

ChIP K-562 GSE70764.CTCFL.K-562 149 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF274GAT 251 bp overlap

E2F6 3 datasets

Motif DE_24h DE_24h-E2F6_MA0471.3 8 bp overlap

ChIP H1 ENCFF785DWK 310 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 251 bp overlap

ChIP K-562 ENCSR000BMD.ELF1.K-562 200 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 272 bp overlap

ChIP K-562_DOX GSE23730.ERG.K-562_DOX 206 bp overlap

ESR1 14 datasets

ChIP Ishikawa_DMSO GSE132426.ESR1.Ishikawa_DMSO 269 bp overlap

ChIP Ishikawa_ETV4-KO1_Mili GSE129803.ESR1.Ishikawa_ETV4-KO1_Mili 221 bp overlap

ChIP Ishikawa_ETV4-KO2_Mili GSE129803.ESR1.Ishikawa_ETV4-KO2_Mili 161 bp overlap

ChIP Ishikawa_siETV4-72h GSE129803.ESR1.Ishikawa_siETV4-72h 308 bp overlap

ChIP Ishikawa_siNTC-72h GSE129803.ESR1.Ishikawa_siNTC-72h 595 bp overlap

ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 279 bp overlap

ChIP MCF-7 GSE148277.ESR1.MCF-7 316 bp overlap

ChIP MCF-7 GSE48930.ESR1.MCF-7 181 bp overlap

ChIP MCF-7_E2 GSE73956.ESR1.MCF-7_E2 106 bp overlap

ChIP MCF-7_IL1b-ICI GSE67295.ESR1.MCF-7_IL1b-ICI 155 bp overlap

ChIP MCF-7_Y537S_DMSO GSE148277.ESR1.MCF-7_Y537S_DMSO 260 bp overlap

ChIP MDA-MB-231_LQ_45min GSE95121.ESR1.MDA-MB-231_LQ_45min 228 bp overlap

ChIP T-47D_D538G_E2 GSE148277.ESR1.T-47D_D538G_E2 336 bp overlap

ChIP breast_tumor_Male_21 GSE104399.ESR1.breast_tumor_Male_21 274 bp overlap

FLI1 3 datasets

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 212 bp overlap

ChIP A-673_2_KRAB_eSOX2_1 GSE106914.FLI1.A-673_2_KRAB_eSOX2_1 262 bp overlap

ChIP UAE_ZINC GSE23730.FLI1.UAE_ZINC 225 bp overlap

FOXA2 1 dataset

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 384 bp overlap

GABPB1 1 dataset

ChIP K-562 ENCSR138YYY.GABPB1.K-562 249 bp overlap

HDAC2 2 datasets

ChIP K-562 ENCSR893WSB.HDAC2.K-562 516 bp overlap

ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 95 bp overlap

ChIP K-562 ENCSR563YDA.HDGF.K-562 162 bp overlap

ChIP OCI-AML-3 GSE133516.KAT7.OCI-AML-3 174 bp overlap

KDM4A 3 datasets

ChIP H1 ENCFF078LED 584 bp overlap

ChIP H1 ENCFF078LED 404 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 161 bp overlap

KLF10 3 datasets

Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap

Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap

Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap

KLF12 2 datasets

Motif DE_24h DE_24h-KLF12_MA0742.2 9 bp overlap

Motif DE_24h DE_24h-KLF12_MA0742.2 9 bp overlap

KLF14 3 datasets

Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap

Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap

Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap

KLF5 2 datasets

Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap

Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap

KLF7 2 datasets

Motif DE_24h DE_24h-KLF7_MA1959.2 8 bp overlap

Motif DE_24h DE_24h-KLF7_MA1959.2 8 bp overlap

ChIP Ishikawa ENCFF064TDQ 453 bp overlap

ChIP Ishikawa ENCSR000BTY.MAX.Ishikawa 161 bp overlap

ChIP K562 ENCFF524IJO 397 bp overlap

Motif DE_24h DE_24h-MAZ_MA1522.2 8 bp overlap

Motif DE_24h DE_24h-MAZ_MA1522.2 8 bp overlap

Motif DE_24h DE_24h-MTF1_MA0863.1 14 bp overlap

MYBL2 2 datasets

ChIP WTC11 ENCFF166TKT 497 bp overlap

ChIP WTC11 ENCFF166TKT 317 bp overlap

MYOCD 1 dataset

ChIP A-549 GSE128921.MYOCD.A-549 448 bp overlap

MYOD1 1 dataset

ChIP myoblast GSE50413.MYOD1.myoblast 142 bp overlap

NELFE 1 dataset

ChIP K-562_HS GSE112379.NELFE.K-562_HS 275 bp overlap

NR3C1 1 dataset

ChIP breast_tumor_Male_21 GSE104399.NR3C1.breast_tumor_Male_21 69 bp overlap

NRF1 12 datasets

ChIP HMEC-1 GSE67867.NRF1.HMEC-1 115 bp overlap

ChIP K-562 ENCSR998AJK.NRF1.K-562 527 bp overlap

ChIP K-562 ENCSR494TDU.NRF1.K-562 540 bp overlap

ChIP K-562 ENCSR837EYC.NRF1.K-562 272 bp overlap

ChIP K-562_Ab_R157-1-3D4 GSE97661.NRF1.K-562_Ab_R157-1-3D4 257 bp overlap

ChIP K-562_Ab_R157-1-3H3 GSE97661.NRF1.K-562_Ab_R157-1-3H3 177 bp overlap

ChIP K562 ENCFF130SGK 411 bp overlap

ChIP K562 ENCFF130SGK 402 bp overlap

ChIP K562 ENCFF689EWI 328 bp overlap

ChIP K562 ENCFF689EWI 140 bp overlap

ChIP K562 ENCFF791UHF 302 bp overlap

ChIP K562 ENCFF791UHF 496 bp overlap

OGG1 4 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 366 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 335 bp overlap

ChIP HEK293_30_min GSE89017.OGG1.HEK293_30_min 402 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 368 bp overlap

ChIP HCT-116_ab20662 GSE97527.PAF1.HCT-116_ab20662 234 bp overlap

PATZ1 3 datasets

Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap

Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap

Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap

POLR2A 2 datasets

ChIP spleen ENCFF446ZGT 297 bp overlap

ChIP spleen ENCFF706IUS 289 bp overlap

POLR2G 1 dataset

ChIP K562 ENCFF047BLG 544 bp overlap

POU2F1 1 dataset

ChIP T-47D_D538G GSE148277.POU2F1.T-47D_D538G 255 bp overlap

POU5F1 2 datasets

ChIP BJ1-hTERT GSE92491.POU5F1.BJ1-hTERT 170 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 197 bp overlap

ChIP hiPSC_D2 GSE132532.RARA.hiPSC_D2 188 bp overlap

RBFOX2 2 datasets

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 347 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 336 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 483 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 536 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 520 bp overlap

RPA2_phospho 1 dataset

ChIP HeLa GSE108172.RPA2_phospho.HeLa 131 bp overlap

RUNX2 2 datasets

ChIP Karpas-45 GSE151819.RUNX2.Karpas-45 349 bp overlap

ChIP LNCaP-C4-2B GSE33889.RUNX2.LNCaP-C4-2B 244 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.RXR.pancreatic-progenitor_PP1 193 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 436 bp overlap

SAFB 4 datasets

ChIP K-562 GSE120104.SAFB.K-562 147 bp overlap

ChIP K-562 ENCSR072VUO.SAFB.K-562 147 bp overlap

ChIP K562 ENCFF765XSF 371 bp overlap

ChIP K562 ENCFF916WYW 371 bp overlap

SETDB1 1 dataset

ChIP K-562 ENCSR000EWI.SETDB1.K-562 239 bp overlap

SMAD2-3 1 dataset

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 538 bp overlap

SMARCA4 3 datasets

ChIP Aska-SS GSE108025.SMARCA4.Aska-SS 154 bp overlap

ChIP Aska-SS_shSSX GSE108025.SMARCA4.Aska-SS_shSSX 275 bp overlap

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 654 bp overlap

SMARCC1 1 dataset

ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 654 bp overlap

ChIP DKO GSE131606.SMC1.DKO 330 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 186 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 93 bp overlap

Motif DE_24h DE_24h-SP1_MA0079.5 9 bp overlap

Motif DE_24h DE_24h-SP1_MA0079.5 9 bp overlap

Motif DE_24h DE_24h-SP1_MA0079.5 9 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 130 bp overlap

ChIP WTC11 ENCFF688PEU 501 bp overlap

ChIP WTC11 ENCFF688PEU 384 bp overlap

Motif DE_24h DE_24h-SP2_MA0516.3 9 bp overlap

Motif DE_24h DE_24h-SP2_MA0516.3 9 bp overlap

Motif DE_24h DE_24h-SP2_MA0516.3 9 bp overlap

Motif DE_24h DE_24h-SP4_MA0685.2 9 bp overlap

Motif DE_24h DE_24h-SP4_MA0685.2 9 bp overlap

ChIP WA01 ENCSR000BQV.SP4.WA01 216 bp overlap

Motif DE_24h DE_24h-SP5_MA1965.2 6 bp overlap

Motif DE_24h DE_24h-SP5_MA1965.2 6 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 547 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 405 bp overlap

ChIP Aska-SS GSE108025.SS18.Aska-SS 272 bp overlap

ChIP Ishikawa ENCSR000BTO.TAF1.Ishikawa 131 bp overlap

TAF15 2 datasets

ChIP Hep-G2 ENCSR825MZS.TAF15.Hep-G2 193 bp overlap

ChIP Hep-G2 GSE120104.TAF15.Hep-G2 187 bp overlap

ChIP GEN2-2 GSE76147.TCF4.GEN2-2 588 bp overlap

TEAD4 2 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 470 bp overlap

ChIP Ishikawa ENCSR000BSW.TEAD4.Ishikawa 115 bp overlap

TFAP2A 1 dataset

ChIP WA09 GSE105081.TFAP2A.WA09 204 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 654 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 319 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 257 bp overlap

TP63 2 datasets

ChIP SUIT-2 GSE115461.TP63.SUIT-2 206 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 286 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 199 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 494 bp overlap

ZBED4 1 dataset

Motif DE_24h DE_24h-ZBED4_MA2328.1 10 bp overlap

ZBTB33 2 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 640 bp overlap

ChIP K562 ENCFF875HLX 465 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 654 bp overlap

ZBTB6 1 dataset

Motif DE_24h DE_24h-ZBTB6_MA1581.2 9 bp overlap

ZBTB7A 2 datasets

ChIP Ishikawa ENCFF191NFH 325 bp overlap

ChIP Ishikawa ENCSR000BSZ.ZBTB7A.Ishikawa 98 bp overlap

ZFP14 1 dataset

Motif DE_24h DE_24h-ZFP14_MA1972.1 15 bp overlap

ZNF148 2 datasets

Motif DE_24h DE_24h-ZNF148_MA1653.2 10 bp overlap

Motif DE_24h DE_24h-ZNF148_MA1653.2 10 bp overlap

ZNF530 1 dataset

Motif DE_24h DE_24h-ZNF530_MA1981.2 14 bp overlap

ZNF547 1 dataset

Motif DE_24h DE_24h-ZNF547_MA2334.1 13 bp overlap

ZNF610 2 datasets

Motif DE_24h DE_24h-ZNF610_MA1713.2 10 bp overlap

Motif DE_24h DE_24h-ZNF610_MA1713.2 10 bp overlap

ZNF629 1 dataset

ChIP Hep-G2 ENCSR363ASY.ZNF629.Hep-G2 175 bp overlap