chr1 : 81,804,290 – 81,804,550

260 bp 95 TFs 1 linked gene

This 260 bp open chromatin element is linked to ADGRL2 and is bound by 95 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ADGRL2		3.9 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

95 transcription factors

ARID1A 1 dataset

ChIP HAP1 GSE108387.ARID1A.HAP1 260 bp overlap

ARID2 2 datasets

ChIP BIN-67_ctrl GSE117734.ARID2.BIN-67_ctrl 122 bp overlap

ChIP Hep-G2 GSE69566.ARID2.Hep-G2 260 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 122 bp overlap

ATRX 1 dataset

ChIP metastatic-neuroblastoma_CHLA90 GSE100148.ATRX.metastatic-neuroblastoma_CHLA90 196 bp overlap

Arid3b 1 dataset

Motif DE_12h DE_12h-Arid3b_MA0601.2 7 bp overlap

BCOR 2 datasets

ChIP WA01 GSE104690.BCOR.WA01 168 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 219 bp overlap

BMI1 1 dataset

ChIP GM12878 ENCSR469WII.BMI1.GM12878 260 bp overlap

BRD3 2 datasets

ChIP THP-1_DMSO-PMA GSE138084.BRD3.THP-1_DMSO-PMA 260 bp overlap

ChIP THP-1_iBET-BD2-PMA GSE138084.BRD3.THP-1_iBET-BD2-PMA 66 bp overlap

BRD4 4 datasets

ChIP HCC1395 GSE63581.BRD4.HCC1395 260 bp overlap

ChIP SK-N-BE2-C_Resistant-veh GSE107706.BRD4.SK-N-BE2-C_Resistant-veh 260 bp overlap

ChIP THP-1_DMSO-PMA GSE138084.BRD4.THP-1_DMSO-PMA 243 bp overlap

ChIP THP-1_iBET-BD2 GSE138084.BRD4.THP-1_iBET-BD2 197 bp overlap

CDK9 1 dataset

ChIP Kelly_CYC065 GSE107126.CDK9.Kelly_CYC065 189 bp overlap

CHD7 2 datasets

ChIP WA01 ENCSR000AVA.CHD7.WA01 174 bp overlap

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 260 bp overlap

CTNNB1 1 dataset

ChIP hESC_YAP-_activinA_15h GSE99202.CTNNB1.hESC_YAP-_activinA_15h 260 bp overlap

DPF2 2 datasets

ChIP BIN-67_ctrl GSE117734.DPF2.BIN-67_ctrl 204 bp overlap

ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.DPF2.BIN-67_lentivirus-SMARCA4-T910M 196 bp overlap

DUX4 1 dataset

Motif DE_12h DE_12h-DUX4_MA0468.1 11 bp overlap

EOMES 2 datasets

Motif DE_12h DE_12h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 171 bp overlap

ERF::FOXI1 1 dataset

Motif DE_12h DE_12h-ERFFOXI1_MA1935.2 10 bp overlap

ERF::FOXO1 1 dataset

Motif DE_12h DE_12h-ERFFOXO1_MA1936.2 12 bp overlap

EZH2 3 datasets

ChIP A673 ENCFF955JRZ 260 bp overlap

ChIP KG-1_shPLZF GSE109619.EZH2.KG-1_shPLZF 245 bp overlap

ChIP keratinocyte ENCSR000ARK.EZH2.keratinocyte 260 bp overlap

EZH2_phosphoT487 1 dataset

ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 253 bp overlap

Elf5 1 dataset

Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap

FOXJ2::ELF1 1 dataset

Motif DE_12h DE_12h-FOXJ2ELF1_MA1952.2 11 bp overlap

FOXO1::ELK1 1 dataset

Motif DE_12h DE_12h-FOXO1ELK1_MA1954.2 13 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 152 bp overlap

GATA6 4 datasets

ChIP DE_D1 S09-DE-d1-GATA6-exp1 260 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 260 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 260 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 260 bp overlap

Hnf1A 1 dataset

Motif DE_12h DE_12h-Hnf1A_MA1991.2 10 bp overlap

IKZF1 1 dataset

Motif DE_12h DE_12h-IKZF1_MA1508.2 8 bp overlap

IKZF2 1 dataset

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

INO80 1 dataset

ChIP Huh-7 GSE97411.INO80.Huh-7 260 bp overlap

JUN 4 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 260 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 260 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 260 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 260 bp overlap

KLF4 1 dataset

ChIP HAP1 GSE130417.KLF4.HAP1 130 bp overlap

KMT2A 2 datasets

ChIP HEK293T_C-term_shCtrl_TASP1-KO GSE90762.KMT2A.HEK293T_C-term_shCtrl_TASP1-KO 228 bp overlap

ChIP HEK293T_N-term_shCtrl_TASP1-KO GSE90762.KMT2A.HEK293T_N-term_shCtrl_TASP1-KO 193 bp overlap

LIN54 1 dataset

Motif DE_12h DE_12h-LIN54_MA0619.2 7 bp overlap

Lef1 1 dataset

Motif DE_12h DE_12h-Lef1_MA0768.3 8 bp overlap

Lhx3 1 dataset

Motif DE_12h DE_12h-Lhx3_MA0135.2 12 bp overlap

MCRS1 1 dataset

ChIP Huh-7 GSE97411.MCRS1.Huh-7 208 bp overlap

MED1 2 datasets

ChIP MOLM-14 GSE65138.MED1.MOLM-14 187 bp overlap

ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 260 bp overlap

MGA 1 dataset

Motif DE_12h DE_12h-MGA_MA0801.1 8 bp overlap

MGA::EVX1 1 dataset

Motif DE_12h DE_12h-MGAEVX1_MA1960.2 11 bp overlap

MYC 1 dataset

ChIP CC-LP-1 GSE124430.MYC.CC-LP-1 124 bp overlap

NANOG 8 datasets

ChIP GM23338 ENCFF065NZG 260 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 202 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 260 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 178 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 260 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 260 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 260 bp overlap

ChIP hESC GSE18292.NANOG.hESC 107 bp overlap

NIPBL 2 datasets

ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 202 bp overlap

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 216 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 215 bp overlap

PCGF2 2 datasets

ChIP HEK293T_PCGF2fl GSE119618.PCGF2.HEK293T_PCGF2fl 171 bp overlap

ChIP fibroblast_OHT GSE55605.PCGF2.fibroblast_OHT 186 bp overlap

PHIP 1 dataset

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 238 bp overlap

POU1F1 1 dataset

Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap

POU2F1 1 dataset

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 1 dataset

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU5F1 10 datasets

ChIP GM23338 ENCFF333SNB 260 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 260 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 260 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 260 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 260 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 260 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 227 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 260 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 260 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 240 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

PRDM1 1 dataset

ChIP HEK293 ENCFF302TBP 52 bp overlap

PRDM10 1 dataset

ChIP HEK293 ENCFF145WQQ 136 bp overlap

PSIP1 1 dataset

ChIP T-REx-293 GSE117155.PSIP1.T-REx-293 224 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

RAD21 2 datasets

ChIP HAP1 GSE152721.RAD21.HAP1 239 bp overlap

ChIP neural cell ENCFF564MOT 260 bp overlap

RNF2 1 dataset

ChIP GM12878 ENCSR679FAB.RNF2.GM12878 193 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 260 bp overlap

SAP30 1 dataset

ChIP WA01 ENCSR000ATR.SAP30.WA01 60 bp overlap

SIN3A 2 datasets

ChIP SK-N-SH ENCSR000BPB.SIN3A.SK-N-SH 140 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 224 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 260 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 260 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 260 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 260 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 260 bp overlap

SMARCA4 6 datasets

ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-T910M 152 bp overlap

ChIP NPC_siCT GSE122631.SMARCA4.NPC_siCT 260 bp overlap

ChIP NPC_siSOX GSE122631.SMARCA4.NPC_siSOX 260 bp overlap

ChIP WA09 GSE105028.SMARCA4.WA09 234 bp overlap

ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 260 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 260 bp overlap

SMARCB1 3 datasets

ChIP RMG-I_ARID1A-KO GSE120058.SMARCB1.RMG-I_ARID1A-KO 227 bp overlap

ChIP hiPSC GSE124903.SMARCB1.hiPSC 260 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 260 bp overlap

SMARCC1 7 datasets

ChIP BIN-67_ctrl GSE117734.SMARCC1.BIN-67_ctrl 205 bp overlap

ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SMARCC1.BIN-67_lentivirus-SMARCA4-T910M 165 bp overlap

ChIP DE_D1 S10-DE-d1-BAF155-exp1 260 bp overlap

ChIP DE_D1 S15-DE-d1-BAF155-exp1 85 bp overlap

ChIP SYO-1_shCt GSE139053.SMARCC1.SYO-1_shCt 67 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 260 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 260 bp overlap

SOX2 8 datasets

ChIP HNSC GSE69479.SOX2.HNSC 260 bp overlap

ChIP NPC GSE122631.SOX2.NPC 260 bp overlap

ChIP RENVM GSE49404.SOX2.RENVM 174 bp overlap

ChIP hESC GSE18292.SOX2.hESC 100 bp overlap

ChIP hiPSC GSE67282.SOX2.hiPSC 260 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 260 bp overlap

ChIP hiPSC_KDP53 GSE67282.SOX2.hiPSC_KDP53 234 bp overlap

ChIP hiPSC_KDP53_INHI GSE67282.SOX2.hiPSC_KDP53_INHI 260 bp overlap

SOX3 1 dataset

ChIP NPC GSE122631.SOX3.NPC 260 bp overlap

SPIC 1 dataset

Motif DE_12h DE_12h-SPIC_MA0687.2 13 bp overlap

SS18 3 datasets

ChIP Aska-SS_BAF47KO1 GSE108025.SS18.Aska-SS_BAF47KO1 219 bp overlap

ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SS18.BIN-67_lentivirus-SMARCA4-T910M 236 bp overlap

ChIP SYO-1_shCt GSE139053.SS18.SYO-1_shCt 260 bp overlap

SUZ12 1 dataset

ChIP MCF-7 ENCSR757EMK.SUZ12.MCF-7 92 bp overlap

Sox1 1 dataset

Motif DE_12h DE_12h-Sox1_MA0870.1 15 bp overlap

T 1 dataset

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 224 bp overlap

TBR1 1 dataset

Motif DE_12h DE_12h-TBR1_MA0802.2 9 bp overlap

TBX1 1 dataset

Motif DE_12h DE_12h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_12h DE_12h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_12h DE_12h-TBX2_MA0688.2 9 bp overlap

TBX21 1 dataset

Motif DE_12h DE_12h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap

TBX4 1 dataset

Motif DE_12h DE_12h-TBX4_MA0806.1 8 bp overlap

TCF7 1 dataset

Motif DE_12h DE_12h-TCF7_MA0769.3 7 bp overlap

TCF7L1 1 dataset

Motif DE_12h DE_12h-TCF7L1_MA1421.1 12 bp overlap

TCF7L2 1 dataset

Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 258 bp overlap

Tbx6 1 dataset

Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap

WDR5 1 dataset

ChIP breast-cancer_shLuc GSE113279.WDR5.breast-cancer_shLuc 239 bp overlap

YY1 1 dataset

ChIP liver ENCFF400MBC 170 bp overlap

ZNF24 1 dataset

Motif DE_12h DE_12h-ZNF24_MA1124.1 13 bp overlap

ZNF274 2 datasets

Motif DE_12h DE_12h-ZNF274_MA1592.2 12 bp overlap

ChIP H1 ENCFF434LDY 260 bp overlap

ZNF573 1 dataset

ChIP HEK293T GSE78099.ZNF573.HEK293T 260 bp overlap

ZNF766 1 dataset

Motif DE_12h DE_12h-ZNF766_MA2098.1 9 bp overlap