chr4 : 79,445,356 – 79,445,949

593 bp 110 TFs 0 linked genes

This 593 bp open chromatin element has no linked target genes and is bound by 110 transcription factors.

Linked Genes

No linked genes

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

110 transcription factors

ASXL3 1 dataset

ChIP NCI-H1963_Ab1 GSE145028.ASXL3.NCI-H1963_Ab1 350 bp overlap

BAP1 2 datasets

ChIP NCI-H1963_shASXL3 GSE145028.BAP1.NCI-H1963_shASXL3 281 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BAP1.NCI-H1963_shNONT 466 bp overlap

BCL11A 1 dataset

ChIP HEK293 ENCSR021DJC.BCL11A.HEK293 292 bp overlap

BCOR 1 dataset

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 276 bp overlap

BRD3 1 dataset

ChIP HUVEC-C_MS417 GSE60171.BRD3.HUVEC-C_MS417 209 bp overlap

BRD4 11 datasets

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 457 bp overlap

ChIP NCI-H1963 GSE145028.BRD4.NCI-H1963 392 bp overlap

ChIP NCI-H1963_dBET6 GSE145028.BRD4.NCI-H1963_dBET6 385 bp overlap

ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 456 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 455 bp overlap

ChIP NCI-H2171 GSE101821.BRD4.NCI-H2171 458 bp overlap

ChIP NCI-H2171_DMSO GSE49224.BRD4.NCI-H2171_DMSO 416 bp overlap

ChIP RH4 GSE83726.BRD4.RH4 451 bp overlap

ChIP RH4_shCHD4 GSE140115.BRD4.RH4_shCHD4 501 bp overlap

ChIP RH4_shscr GSE140115.BRD4.RH4_shscr 440 bp overlap

ChIP cortical-interneuron GSE117508.BRD4.cortical-interneuron 187 bp overlap

CASZ1 1 dataset

ChIP rhabdomyosarcoma_DOX GSE126142.CASZ1.rhabdomyosarcoma_DOX 539 bp overlap

CREB3L1 1 dataset

Motif DE_12h DE_12h-CREB3L1_MA0839.2 13 bp overlap

E2F7 1 dataset

Motif DE_12h DE_12h-E2F7_MA0758.1 14 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 146 bp overlap

EP300 3 datasets

ChIP neural ENCSR843ZUP.EP300.neural 389 bp overlap

ChIP neural cell ENCFF442QNK 343 bp overlap

ChIP neural cell ENCFF442QNK 352 bp overlap

ETS1 3 datasets

ChIP HUVEC-C_12h GSE93030.ETS1.HUVEC-C_12h 179 bp overlap

ChIP HUVEC-C_VEGF_12H GSE41166.ETS1.HUVEC-C_VEGF_12H 166 bp overlap

ChIP HUVEC-C_VEGF_12h GSE109625.ETS1.HUVEC-C_VEGF_12h 179 bp overlap

EZH2 1 dataset

ChIP RH30_DMSO GSE85169.EZH2.RH30_DMSO 221 bp overlap

EZH2_phosphoT487 2 datasets

ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 238 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 287 bp overlap

Elf5 1 dataset

Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap

FLI1 1 dataset

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 250 bp overlap

FOXC2 1 dataset

Motif DE_12h DE_12h-FOXC2_MA0846.2 11 bp overlap

FOXD3 1 dataset

Motif DE_12h DE_12h-FOXD3_MA0041.3 14 bp overlap

FOXE1 1 dataset

Motif DE_12h DE_12h-FOXE1_MA1487.3 12 bp overlap

FOXF2 1 dataset

Motif DE_12h DE_12h-FOXF2_MA0030.2 9 bp overlap

FOXG1 1 dataset

Motif DE_12h DE_12h-FOXG1_MA0613.1 8 bp overlap

FOXK1 1 dataset

Motif DE_12h DE_12h-FOXK1_MA0852.3 7 bp overlap

FOXK2 1 dataset

Motif DE_12h DE_12h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif DE_12h DE_12h-FOXL1_MA0033.2 7 bp overlap

FOXN3 1 dataset

Motif DE_12h DE_12h-FOXN3_MA1489.1 8 bp overlap

FOXO1-PAX3 2 datasets

ChIP RH4_DMSO-6H GSE116344.FOXO1-PAX3.RH4_DMSO-6H 431 bp overlap

ChIP RH4_Entinostat-6H GSE116344.FOXO1-PAX3.RH4_Entinostat-6H 448 bp overlap

FOXO4 1 dataset

Motif DE_12h DE_12h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif DE_12h DE_12h-FOXO6_MA0849.1 7 bp overlap

FOXP2 1 dataset

ChIP SK-N-MC ENCFF865YOS 285 bp overlap

FOXP3 1 dataset

Motif DE_12h DE_12h-FOXP3_MA0850.1 7 bp overlap

Foxf1 1 dataset

Motif DE_12h DE_12h-Foxf1_MA1606.2 7 bp overlap

Foxj2 1 dataset

Motif DE_12h DE_12h-Foxj2_MA0614.1 8 bp overlap

Foxj3 1 dataset

Motif DE_12h DE_12h-Foxj3_MA0851.2 9 bp overlap

Foxo1 1 dataset

Motif DE_12h DE_12h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif DE_12h DE_12h-Foxo3_MA0157.4 7 bp overlap

Foxq1 1 dataset

Motif DE_12h DE_12h-Foxq1_MA0040.2 10 bp overlap

GFI1 1 dataset

ChIP NB4 GSE128528.GFI1.NB4 238 bp overlap

GFI1B 1 dataset

ChIP K-562 ENCSR509GDT.GFI1B.K-562 95 bp overlap

GLIS1 2 datasets

ChIP HEK293 ENCFF299RSE 287 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 423 bp overlap

HDAC2 2 datasets

ChIP RH4_DMSO-6H GSE116344.HDAC2.RH4_DMSO-6H 440 bp overlap

ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 492 bp overlap

HDAC3 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 463 bp overlap

HOXB4 1 dataset

Motif DE_12h DE_12h-HOXB4_MA1499.2 6 bp overlap

HOXC4 1 dataset

Motif DE_12h DE_12h-HOXC4_MA1504.2 6 bp overlap

HOXD4 1 dataset

Motif DE_12h DE_12h-HOXD4_MA1507.2 6 bp overlap

IKZF2 1 dataset

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

IKZF3 1 dataset

ChIP HEK293 ENCSR304AMN.IKZF3.HEK293 346 bp overlap

ISL1 1 dataset

ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 364 bp overlap

MAFA 1 dataset

Motif DE_12h DE_12h-MAFA_MA1521.2 13 bp overlap

MAFB 1 dataset

ChIP islet ERP004003.MAFB.islet 151 bp overlap

MAFF 1 dataset

Motif DE_12h DE_12h-MAFF_MA0495.4 11 bp overlap

MAX 2 datasets

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 467 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 383 bp overlap

MED1 2 datasets

ChIP NCI-H2171 GSE36354.MED1.NCI-H2171 537 bp overlap

ChIP RH4 GSE83726.MED1.RH4 591 bp overlap

MEIS1 1 dataset

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

MTA2 1 dataset

ChIP RH4 GSE155861.MTA2.RH4 593 bp overlap

MYC 1 dataset

ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 403 bp overlap

MYCN 2 datasets

ChIP CHP-134 GSE129588.MYCN.CHP-134 293 bp overlap

ChIP RH4 GSE83726.MYCN.RH4 535 bp overlap

MYOD1 3 datasets

ChIP RD_shSNAI2 GSE137168.MYOD1.RD_shSNAI2 434 bp overlap

ChIP RH30_DMSO GSE85169.MYOD1.RH30_DMSO 464 bp overlap

ChIP SMS-CTR GSE137168.MYOD1.SMS-CTR 326 bp overlap

MYOG 2 datasets

ChIP RH4_DMSO-6H GSE116344.MYOG.RH4_DMSO-6H 286 bp overlap

ChIP RH4_Entinostat-6H GSE116344.MYOG.RH4_Entinostat-6H 212 bp overlap

MZF1 1 dataset

ChIP HEK293 ENCSR298QUH.MZF1.HEK293 352 bp overlap

Mafb 1 dataset

Motif DE_12h DE_12h-Mafb_MA0117.3 11 bp overlap

NANOG 2 datasets

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 240 bp overlap

ChIP hESC GSE18292.NANOG.hESC 95 bp overlap

NEUROD1 2 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 386 bp overlap

ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 395 bp overlap

NFYA 1 dataset

Motif DE_12h DE_12h-NFYA_MA0060.4 8 bp overlap

NFYC 1 dataset

Motif DE_12h DE_12h-NFYC_MA1644.2 7 bp overlap

NKX2-5 1 dataset

ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 210 bp overlap

NKX3-1 1 dataset

ChIP islet ERP004003.NKX3-1.islet 391 bp overlap

NRL 1 dataset

Motif DE_12h DE_12h-NRL_MA0842.3 12 bp overlap

OSR2 3 datasets

ChIP HEK293 ENCFF875BDB 197 bp overlap

ChIP HEK293 ENCSR324LTM.OSR2.HEK293 391 bp overlap

ChIP HEK293 GSE76494.OSR2.HEK293 195 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH4 GSE140115.PAX3-FOXO1.RH4 338 bp overlap

PAX7 1 dataset

ChIP H9_DOX GSE98976.PAX7.H9_DOX 257 bp overlap

PDX1 2 datasets

ChIP islet ERP001456.PDX1.islet 125 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 369 bp overlap

PHIP 1 dataset

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 296 bp overlap

PKNOX1 1 dataset

ChIP HEK293T ENCSR233FAG.PKNOX1.HEK293T 148 bp overlap

POLR2A 1 dataset

ChIP neural cell ENCFF604SPB 329 bp overlap

POU5F1 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR362VCG.POU5F1.neuron_bipolar_doxy_4d 237 bp overlap

POU6F1 1 dataset

Motif DE_12h DE_12h-POU6F1_MA1549.2 7 bp overlap

POU6F2 1 dataset

Motif DE_12h DE_12h-POU6F2_MA0793.2 9 bp overlap

PRDM1 1 dataset

Motif DE_12h DE_12h-PRDM1_MA0508.4 7 bp overlap

Prdm4 1 dataset

Motif DE_12h DE_12h-Prdm4_MA1647.3 11 bp overlap

RAD21 1 dataset

ChIP RH4 GSE83726.RAD21.RH4 253 bp overlap

RARA 2 datasets

ChIP hiPSC_D3 GSE109172.RARA.hiPSC_D3 234 bp overlap

ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 439 bp overlap

REST 2 datasets

ChIP neural ENCSR000BTV.REST.neural 350 bp overlap

ChIP neural cell ENCFF882LXX 318 bp overlap

SIX1 1 dataset

Motif DE_12h DE_12h-SIX1_MA1118.2 9 bp overlap

SIX2 4 datasets

Motif DE_12h DE_12h-SIX2_MA1119.2 11 bp overlap

ChIP HEK GSE73865.SIX2.HEK 508 bp overlap

ChIP kidney_fetal_16w GSE75948.SIX2.kidney_fetal_16w 470 bp overlap

ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 411 bp overlap

SMARCA4 2 datasets

ChIP NGP_ARID1A-het GSE134626.SMARCA4.NGP_ARID1A-het 262 bp overlap

ChIP NPC_K755R-siAP GSE122631.SMARCA4.NPC_K755R-siAP 233 bp overlap

SMARCC1 3 datasets

ChIP Aska-SS GSE108025.SMARCC1.Aska-SS 277 bp overlap

ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 412 bp overlap

ChIP SK-N-MC GSE94275.SMARCC1.SK-N-MC 248 bp overlap

SMC1A-B 1 dataset

ChIP Kelly_shLUC-res GSE115248.SMC1A-B.Kelly_shLUC-res 199 bp overlap

SOX8 3 datasets

ChIP RH4 GSE116344.SOX8.RH4 465 bp overlap

ChIP RH4_DMSO-6H GSE116344.SOX8.RH4_DMSO-6H 300 bp overlap

ChIP RH4_Entinostat-6H GSE116344.SOX8.RH4_Entinostat-6H 408 bp overlap

SPIB 1 dataset

Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap

SRY 1 dataset

Motif DE_12h DE_12h-SRY_MA0084.2 7 bp overlap

Spi1 1 dataset

Motif DE_12h DE_12h-Spi1_MA0080.7 13 bp overlap

TBP 1 dataset

ChIP K-562 GSE55306.TBP.K-562 197 bp overlap

TBX5 5 datasets

ChIP G296S GSE85628.TBX5.G296S 243 bp overlap

ChIP G296S_2 GSE85628.TBX5.G296S_2 243 bp overlap

ChIP G296S_4 GSE85628.TBX5.G296S_4 291 bp overlap

ChIP cardiomyocyte_5 GSE85628.TBX5.cardiomyocyte_5 352 bp overlap

ChIP hiPSC GSE81585.TBX5.hiPSC 304 bp overlap

TRIM28 3 datasets

ChIP HEK293 ENCFF265CEM 520 bp overlap

ChIP HEK293 ENCSR618HNF.TRIM28.HEK293 296 bp overlap

ChIP U2OS ENCSR000EYC.TRIM28.U2OS 290 bp overlap

WT1 2 datasets

ChIP HEK293 ENCFF906HIR 377 bp overlap

ChIP HEK293 ENCSR966PJJ.WT1.HEK293 421 bp overlap

YY1 1 dataset

ChIP RH4_DMSO-6H GSE116344.YY1.RH4_DMSO-6H 199 bp overlap

ZBTB12 1 dataset

Motif DE_12h DE_12h-ZBTB12_MA1649.2 7 bp overlap

ZBTB42 1 dataset

ChIP HEK293 GSE76494.ZBTB42.HEK293 284 bp overlap

ZEB1 1 dataset

ChIP HEK293 ENCSR909HMT.ZEB1.HEK293 290 bp overlap

ZEB2 1 dataset

ChIP HEK293 ENCSR417VWF.ZEB2.HEK293 355 bp overlap

ZFP69B 1 dataset

ChIP HEK293T GSE78099.ZFP69B.HEK293T 175 bp overlap

ZNF184 1 dataset

ChIP HEK293 ENCSR020UPN.ZNF184.HEK293 269 bp overlap

ZNF189 1 dataset

ChIP HEK293 ENCSR163RYW.ZNF189.HEK293 384 bp overlap

ZNF416 1 dataset

Motif DE_12h DE_12h-ZNF416_MA1979.2 10 bp overlap

ZNF479 1 dataset

ChIP HEK293T GSE78099.ZNF479.HEK293T 82 bp overlap

ZNF682 1 dataset

Motif DE_12h DE_12h-ZNF682_MA1599.2 11 bp overlap

ZNF75D 1 dataset

Motif DE_12h DE_12h-ZNF75D_MA1601.2 12 bp overlap

ZSCAN31 1 dataset

Motif DE_12h DE_12h-ZSCAN31_MA1722.2 18 bp overlap

ZSCAN5C 1 dataset

ChIP HEK293 ENCSR731AGO.ZSCAN5C.HEK293 193 bp overlap

Zfx 1 dataset

Motif DE_12h DE_12h-Zfx_MA0146.3 10 bp overlap