chr4 : 48,461,004 – 48,461,660

656 bp 106 TFs 0 linked genes

This 656 bp open chromatin element has no linked target genes and is bound by 106 transcription factors.

Linked Genes

No linked genes

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

106 transcription factors

ATF2 1 dataset

Motif DE_60h DE_60h-ATF2_MA1632.2 10 bp overlap

ATF3 1 dataset

ChIP HCT-116_CAMP GSE74355.ATF3.HCT-116_CAMP 122 bp overlap

BARX1 1 dataset

Motif DE_60h DE_60h-BARX1_MA0875.2 6 bp overlap

BRD4 1 dataset

ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 216 bp overlap

BSX 1 dataset

Motif DE_60h DE_60h-BSX_MA0876.2 6 bp overlap

CTCF 1 dataset

ChIP GM23338 ENCFF772DML 201 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF844FIP 216 bp overlap

DLX1 1 dataset

Motif DE_60h DE_60h-DLX1_MA0879.3 6 bp overlap

DLX6 1 dataset

Motif DE_60h DE_60h-DLX6_MA0882.2 6 bp overlap

Dlx2 1 dataset

Motif DE_60h DE_60h-Dlx2_MA0885.3 8 bp overlap

Dlx3 1 dataset

Motif DE_60h DE_60h-Dlx3_MA0880.2 6 bp overlap

Dlx4 1 dataset

Motif DE_60h DE_60h-Dlx4_MA0881.2 6 bp overlap

Dlx5 1 dataset

Motif DE_60h DE_60h-Dlx5_MA1476.3 8 bp overlap

EOMES 3 datasets

Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap

Motif DE_72h DE_72h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 417 bp overlap

FIGLA 2 datasets

Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap

Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap

FOXA1 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 327 bp overlap

FOXA2 4 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 189 bp overlap

ChIP DE DE-FOXA2-1 644 bp overlap

ChIP DE DE-FOXA2-2 461 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 338 bp overlap

FOXD2 1 dataset

Motif DE_60h DE_60h-FOXD2_MA0847.4 11 bp overlap

FOXE1 1 dataset

Motif DE_60h DE_60h-FOXE1_MA1487.3 12 bp overlap

GATA3 1 dataset

ChIP BE2C GSE65664.GATA3.BE2C 142 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 468 bp overlap

ChIP DE DE-GATA4-2 437 bp overlap

ChIP foregut GSE117136.GATA4.foregut 416 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 656 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 656 bp overlap

GATA6 16 datasets

ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 181 bp overlap

ChIP DE DE-GATA6-1 636 bp overlap

ChIP DE DE-GATA6-2 433 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 480 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 466 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 431 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 406 bp overlap

ChIP H9 ERP004206.GATA6.H9 150 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 396 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 524 bp overlap

ChIP YCC-3 GSE51705.GATA6.YCC-3 197 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 228 bp overlap

ChIP foregut GSE117136.GATA6.foregut 424 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 586 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 297 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 350 bp overlap

GBX2 1 dataset

Motif DE_60h DE_60h-GBX2_MA0890.2 6 bp overlap

HAND2 1 dataset

ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 116 bp overlap

HESX1 1 dataset

Motif DE_60h DE_60h-HESX1_MA0894.2 6 bp overlap

HNF1A 2 datasets

Motif DE_60h DE_60h-HNF1A_MA0046.3 13 bp overlap

Motif DE_72h DE_72h-HNF1A_MA0046.3 13 bp overlap

HNF1B 2 datasets

Motif DE_60h DE_60h-HNF1B_MA0153.2 13 bp overlap

Motif DE_72h DE_72h-HNF1B_MA0153.2 13 bp overlap

HOXA6 1 dataset

Motif DE_60h DE_60h-HOXA6_MA1497.2 7 bp overlap

HOXA7 1 dataset

Motif DE_60h DE_60h-HOXA7_MA1498.3 6 bp overlap

HOXB6 1 dataset

Motif DE_60h DE_60h-HOXB6_MA1500.2 7 bp overlap

HOXB7 1 dataset

Motif DE_60h DE_60h-HOXB7_MA1501.2 7 bp overlap

HOXB8 1 dataset

Motif DE_60h DE_60h-HOXB8_MA1502.2 7 bp overlap

HOXD8 1 dataset

Motif DE_60h DE_60h-HOXD8_MA0910.3 7 bp overlap

Hmx1 1 dataset

Motif DE_60h DE_60h-Hmx1_MA0896.2 9 bp overlap

Hmx2 1 dataset

Motif DE_60h DE_60h-Hmx2_MA0897.2 15 bp overlap

Hmx3 1 dataset

Motif DE_60h DE_60h-Hmx3_MA0898.2 9 bp overlap

IKZF1 1 dataset

Motif DE_60h DE_60h-IKZF1_MA1508.2 8 bp overlap

IKZF2 1 dataset

Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap

ISL1 1 dataset

ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 153 bp overlap

JUN 3 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 478 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 340 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 494 bp overlap

KDM1A 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 458 bp overlap

KLF5 1 dataset

Motif DE_60h DE_60h-KLF5_MA0599.1 10 bp overlap

LBX2 1 dataset

Motif DE_60h DE_60h-LBX2_MA0699.2 6 bp overlap

LHX2 1 dataset

Motif DE_60h DE_60h-LHX2_MA0700.3 6 bp overlap

MGA 2 datasets

Motif DE_60h DE_60h-MGA_MA0801.1 8 bp overlap

Motif DE_72h DE_72h-MGA_MA0801.1 8 bp overlap

MSX1 1 dataset

Motif DE_60h DE_60h-MSX1_MA0666.3 6 bp overlap

MSX2 1 dataset

Motif DE_60h DE_60h-MSX2_MA0708.3 6 bp overlap

MTA2 1 dataset

ChIP GM12878 ENCSR293QAR.MTA2.GM12878 108 bp overlap

Msx3 1 dataset

Motif DE_60h DE_60h-Msx3_MA0709.2 6 bp overlap

NFE2 1 dataset

ChIP ProEs GSE59087.NFE2.ProEs 96 bp overlap

NR2C1 1 dataset

Motif DE_60h DE_60h-NR2C1_MA1535.2 6 bp overlap

NR2C2 1 dataset

Motif DE_60h DE_60h-NR2C2_MA1536.2 6 bp overlap

Nobox 1 dataset

Motif DE_60h DE_60h-Nobox_MA0125.2 6 bp overlap

Nr1H2 1 dataset

Motif DE_60h DE_60h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 1 dataset

Motif DE_60h DE_60h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 1 dataset

Motif DE_60h DE_60h-Nr1h3_MA2337.1 6 bp overlap

OSR2 1 dataset

Motif DE_60h DE_60h-OSR2_MA1646.2 8 bp overlap

PBX3 2 datasets

Motif DE_60h DE_60h-PBX3_MA1114.2 11 bp overlap

Motif DE_72h DE_72h-PBX3_MA1114.2 11 bp overlap

PDX1 5 datasets

ChIP hiPSC GSE125768.PDX1.hiPSC 250 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 150 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 202 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 336 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 175 bp overlap

PSIP1 1 dataset

ChIP T-REx-293 GSE117155.PSIP1.T-REx-293 170 bp overlap

Ptf1A 2 datasets

Motif DE_60h DE_60h-Ptf1A_MA1620.2 8 bp overlap

Motif DE_72h DE_72h-Ptf1A_MA1620.2 8 bp overlap

RAD21 1 dataset

ChIP MCF-7 GSE72082.RAD21.MCF-7 121 bp overlap

RAX 1 dataset

Motif DE_60h DE_60h-RAX_MA0718.2 6 bp overlap

RBPJ 2 datasets

Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap

Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap

RELA 1 dataset

ChIP BJAB_1h-activation GSE117250.RELA.BJAB_1h-activation 163 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 350 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 315 bp overlap

SNAI2 1 dataset

ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 240 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 232 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 332 bp overlap

SP4 1 dataset

Motif DE_60h DE_60h-SP4_MA0685.2 9 bp overlap

SP5 1 dataset

Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap

SPIB 1 dataset

Motif DE_60h DE_60h-SPIB_MA0081.3 13 bp overlap

SPIC 1 dataset

Motif DE_60h DE_60h-SPIC_MA0687.2 13 bp overlap

Spi1 1 dataset

Motif DE_60h DE_60h-Spi1_MA0080.7 13 bp overlap

T 2 datasets

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 233 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 217 bp overlap

TBR1 2 datasets

Motif DE_60h DE_60h-TBR1_MA0802.2 9 bp overlap

Motif DE_72h DE_72h-TBR1_MA0802.2 9 bp overlap

TBX1 2 datasets

Motif DE_60h DE_60h-TBX1_MA0805.1 8 bp overlap

Motif DE_72h DE_72h-TBX1_MA0805.1 8 bp overlap

TBX15 2 datasets

Motif DE_60h DE_60h-TBX15_MA0803.1 8 bp overlap

Motif DE_72h DE_72h-TBX15_MA0803.1 8 bp overlap

TBX18 2 datasets

Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap

Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap

TBX19 1 dataset

Motif DE_60h DE_60h-TBX19_MA0804.2 17 bp overlap

TBX2 2 datasets

Motif DE_60h DE_60h-TBX2_MA0688.2 9 bp overlap

Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap

TBX20 2 datasets

Motif DE_60h DE_60h-TBX20_MA0689.1 11 bp overlap

Motif DE_72h DE_72h-TBX20_MA0689.1 11 bp overlap

TBX21 2 datasets

Motif DE_60h DE_60h-TBX21_MA0690.3 10 bp overlap

Motif DE_72h DE_72h-TBX21_MA0690.3 10 bp overlap

TBX3 2 datasets

Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap

Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap

TBX4 2 datasets

Motif DE_60h DE_60h-TBX4_MA0806.1 8 bp overlap

Motif DE_72h DE_72h-TBX4_MA0806.1 8 bp overlap

TBX5 2 datasets

Motif DE_60h DE_60h-TBX5_MA0807.1 8 bp overlap

Motif DE_72h DE_72h-TBX5_MA0807.1 8 bp overlap

TBXT 1 dataset

Motif DE_60h DE_60h-TBXT_MA0009.2 16 bp overlap

TCF3 1 dataset

ChIP NPC GSE154479.TCF3.NPC 428 bp overlap

TEAD1 1 dataset

Motif DE_60h DE_60h-TEAD1_MA0090.4 9 bp overlap

TEAD2 1 dataset

Motif DE_60h DE_60h-TEAD2_MA1121.2 7 bp overlap

TEAD3 1 dataset

Motif DE_60h DE_60h-TEAD3_MA0808.1 8 bp overlap

TEAD4 3 datasets

ChIP BE2C GSE84389.TEAD4.BE2C 103 bp overlap

Motif DE_60h DE_60h-TEAD4_MA0809.3 8 bp overlap

ChIP SK-N-BE2 GSE84389.TEAD4.SK-N-BE2 103 bp overlap

Tbx6 2 datasets

Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap

Motif DE_72h DE_72h-Tbx6_MA1567.3 9 bp overlap

ZBTB18 2 datasets

Motif DE_60h DE_60h-ZBTB18_MA0698.2 11 bp overlap

Motif DE_72h DE_72h-ZBTB18_MA0698.2 11 bp overlap

ZEB1 2 datasets

Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap

Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap

ZFP14 2 datasets

Motif DE_60h DE_60h-ZFP14_MA1972.1 15 bp overlap

Motif DE_72h DE_72h-ZFP14_MA1972.1 15 bp overlap

ZFP69 1 dataset

ChIP HEK293T GSE78099.ZFP69.HEK293T 217 bp overlap

ZNF24 1 dataset

Motif DE_60h DE_60h-ZNF24_MA1124.1 13 bp overlap

ZNF263 1 dataset

Motif DE_60h DE_60h-ZNF263_MA0528.3 7 bp overlap

ZNF320 2 datasets

Motif DE_60h DE_60h-ZNF320_MA1976.2 20 bp overlap

Motif DE_72h DE_72h-ZNF320_MA1976.2 20 bp overlap

ZNF528 1 dataset

ChIP HEK293 GSE76494.ZNF528.HEK293 243 bp overlap

ZNF675 1 dataset

Motif DE_60h DE_60h-ZNF675_MA1714.2 19 bp overlap

Zfp809 2 datasets

Motif DE_60h DE_60h-Zfp809_MA2125.1 9 bp overlap

Motif DE_72h DE_72h-Zfp809_MA2125.1 9 bp overlap

Zfp961 2 datasets

Motif DE_60h DE_60h-Zfp961_MA2126.1 8 bp overlap

Motif DE_72h DE_72h-Zfp961_MA2126.1 8 bp overlap

Zfx 2 datasets

Motif DE_60h DE_60h-Zfx_MA0146.3 10 bp overlap

Motif DE_72h DE_72h-Zfx_MA0146.3 10 bp overlap