chr1:36,166,478–36,167,190

chr1 : 36,166,478 – 36,167,190

712 bp 85 TFs 12 linked genes

This 712 bp open chromatin element is linked to 12 target genes and is bound by 85 transcription factors.

Linked Genes

12 genes

Gene	Expression	Dist. to TSS	Distance	Link type
MAP7D1		10.7 kb	Distal	Multiome
TRAPPC3		17.4 kb	Distal	Multiome
THRAP3		57.6 kb	Distal	Multiome
ADPRS		77.9 kb	Distal	Multiome
SH3D21		140.3 kb	Distal	Multiome
EVA1B		156.8 kb	Distal	Multiome
STK40		219.1 kb	Distal	Multiome
LSM10		231.1 kb	Distal	Multiome
AGO3		235.6 kb	Distal	Multiome
OSCP1		283.6 kb	Distal	Multiome
AGO1		283.6 kb	Distal	Multiome
MRPS15		297.6 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

85 transcription factors

ATF2 3 datasets

ChIP HEK293 ENCFF194VKZ 257 bp overlap

ChIP HEK293 ENCSR217HTK.ATF2.HEK293 177 bp overlap

ChIP HepG2 ENCFF955VER 233 bp overlap

ATF3 2 datasets

ChIP K562 ENCFF604FPV 92 bp overlap

ChIP primary-dermal-fibroblasts_overexpressed GSE81403.ATF3.primary-dermal-fibroblasts_overexpressed 119 bp overlap

BARX2 1 dataset

Motif DE_72h DE_72h-BARX2_MA1471.2 9 bp overlap

BRD4 2 datasets

ChIP CHL-1 GSE95585.BRD4.CHL-1 252 bp overlap

ChIP IMR-90_QUIES GSE74238.BRD4.IMR-90_QUIES 148 bp overlap

CREBBP 2 datasets

ChIP keratinocyte GSE140991.CREBBP.keratinocyte 277 bp overlap

ChIP keratinocyte_KLF3i GSE140991.CREBBP.keratinocyte_KLF3i 186 bp overlap

CTBP2 1 dataset

ChIP MCF-7 GSE107013.CTBP2.MCF-7 121 bp overlap

DUX4 3 datasets

Motif DE_72h DE_72h-DUX4_MA0468.1 11 bp overlap

ChIP HEK293 GSE75791.DUX4.HEK293 240 bp overlap

ChIP WA01 GSE94322.DUX4.WA01 292 bp overlap

Motif DE_72h DE_72h-DUXA_MA0884.2 13 bp overlap

Motif DE_72h DE_72h-Dux_MA0611.3 11 bp overlap

ChIP K562 ENCFF191BFW 147 bp overlap

ChIP K562 ENCFF511ZZZ 67 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 346 bp overlap

ESRRA 1 dataset

ChIP K562 ENCFF968PEP 62 bp overlap

ESRRG 1 dataset

ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 100 bp overlap

ChIP HCT-116_A7A GSE152144.FOS.HCT-116_A7A 323 bp overlap

FOXA2 4 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 353 bp overlap

ChIP BJ1-hTERT_GATA4 GSE90454.FOXA2.BJ1-hTERT_GATA4 220 bp overlap

ChIP DE DE-FOXA2-1 469 bp overlap

ChIP DE DE-FOXA2-2 424 bp overlap

Foxl2 1 dataset

Motif DE_72h DE_72h-Foxl2_MA1607.2 10 bp overlap

GATA1 1 dataset

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 208 bp overlap

GATA2 2 datasets

ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 298 bp overlap

ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 172 bp overlap

GATA3 1 dataset

ChIP MCF-7_sgScr GSE133072.GATA3.MCF-7_sgScr 188 bp overlap

GATA4 6 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 280 bp overlap

ChIP DE DE-GATA4-1 698 bp overlap

ChIP DE DE-GATA4-2 712 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 273 bp overlap

ChIP foregut GSE117136.GATA4.foregut 370 bp overlap

GATA6 11 datasets

ChIP DE DE-GATA6-1 601 bp overlap

ChIP DE DE-GATA6-2 648 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 645 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 676 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 515 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 712 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 628 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 563 bp overlap

ChIP YCC-3 GSE51705.GATA6.YCC-3 124 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 652 bp overlap

ChIP foregut GSE117136.GATA6.foregut 268 bp overlap

GFI1B 1 dataset

ChIP HEK293 ENCFF264FBS 238 bp overlap

HDAC1 1 dataset

ChIP K-562 ENCSR711VWL.HDAC1.K-562 193 bp overlap

HDAC2 1 dataset

ChIP K562 ENCFF744ALD 60 bp overlap

HDAC8 1 dataset

ChIP K-562 ENCSR835TCD.HDAC8.K-562 316 bp overlap

ChIP K-562 ENCSR197ALX.HDGF.K-562 277 bp overlap

Hmga1 1 dataset

Motif DE_72h DE_72h-Hmga1_MA2124.1 8 bp overlap

INSM2 2 datasets

ChIP HEK293 ENCFF008ZWC 171 bp overlap

ChIP HEK293 ENCSR382GSF.INSM2.HEK293 396 bp overlap

ChIP keratinocyte_DOX GSE135677.IRF2.keratinocyte_DOX 273 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 240 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 651 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 424 bp overlap

KDM1A 1 dataset

ChIP K562 ENCFF128TYE 73 bp overlap

KLF17 2 datasets

ChIP HEK293 ENCFF658MHR 189 bp overlap

ChIP HEK293 ENCSR065WUF.KLF17.HEK293 405 bp overlap

MAML1 1 dataset

ChIP SCC_4h GSE156486.MAML1.SCC_4h 217 bp overlap

MEF2A 1 dataset

Motif DE_72h DE_72h-MEF2A_MA0052.5 10 bp overlap

MEF2C 1 dataset

Motif DE_72h DE_72h-MEF2C_MA0497.2 11 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 128 bp overlap

NCAPH2 1 dataset

ChIP IMR-90_FLAG_OIS GSE118494.NCAPH2.IMR-90_FLAG_OIS 257 bp overlap

NR2F6 1 dataset

ChIP K562 ENCFF674RQA 68 bp overlap

Motif DE_72h DE_72h-OSR1_MA1542.2 8 bp overlap

Motif DE_72h DE_72h-OSR2_MA1646.2 8 bp overlap

ChIP myometrium_NP1 GSE137550.PGR.myometrium_NP1 295 bp overlap

PHOX2A 1 dataset

Motif DE_72h DE_72h-PHOX2A_MA0713.1 11 bp overlap

PHOX2B 1 dataset

Motif DE_72h DE_72h-PHOX2B_MA0681.3 12 bp overlap

POLR2A 2 datasets

ChIP GM12891 ENCFF379FCI 229 bp overlap

ChIP gastroesophageal sphincter ENCFF826EZZ 215 bp overlap

POU2F2 1 dataset

ChIP GM12891 ENCFF166YPP 138 bp overlap

PRDM10 2 datasets

ChIP HEK293 ENCFF145WQQ 52 bp overlap

ChIP K562 ENCFF740YLK 55 bp overlap

PRDM9 1 dataset

Motif DE_72h DE_72h-PRDM9_MA1723.2 20 bp overlap

PROP1 1 dataset

Motif DE_72h DE_72h-PROP1_MA0715.1 11 bp overlap

RBPJ 2 datasets

ChIP SCC_0h GSE156486.RBPJ.SCC_0h 105 bp overlap

ChIP SCC_4h GSE156486.RBPJ.SCC_4h 156 bp overlap

ChIP KB_IL GSE52469.RELA.KB_IL 112 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 589 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 569 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 539 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 448 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 609 bp overlap

SMARCB1 3 datasets

ChIP proliferating-human-fibroblast GSE131711.SMARCB1.proliferating-human-fibroblast 371 bp overlap

ChIP proliferating-human-fibroblast_ASO_Ctrl GSE131711.SMARCB1.proliferating-human-fibroblast_ASO_Ctrl 417 bp overlap

ChIP proliferating-human-fibroblast_ASO_LINC GSE131711.SMARCB1.proliferating-human-fibroblast_ASO_LINC 467 bp overlap

SMC1A 1 dataset

ChIP primary-epidermal-keratinocyte GSE85526.SMC1A.primary-epidermal-keratinocyte 266 bp overlap

SOX10 1 dataset

Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 334 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 498 bp overlap

Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap

ChIP HEK293 ENCSR468IJT.SP7.HEK293 265 bp overlap

SREBP2 2 datasets

ChIP monocyte GSE129202.SREBP2.monocyte 546 bp overlap

ChIP monocyte_TNF GSE129202.SREBP2.monocyte_TNF 585 bp overlap

SSRP1 1 dataset

ChIP HT-1080_AclacinomycinA GSE107595.SSRP1.HT-1080_AclacinomycinA 220 bp overlap

Sox11 1 dataset

Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap

Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap

Stat2 1 dataset

Motif DE_72h DE_72h-Stat2_MA1623.2 10 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 191 bp overlap

ChIP LX2_CALCIPOTRIOL_TGFB1 GSE38103.VDR.LX2_CALCIPOTRIOL_TGFB1 93 bp overlap

VENTX 1 dataset

Motif DE_72h DE_72h-VENTX_MA0724.1 9 bp overlap

ChIP HEK293 ENCFF906HIR 202 bp overlap

ChIP HEK293 ENCSR966PJJ.WT1.HEK293 428 bp overlap

ChIP HCT-116 ENCSR000BNX.YY1.HCT-116 102 bp overlap

ZBTB21 2 datasets

ChIP HEK293 ENCFF509WYZ 278 bp overlap

ChIP HEK293 ENCSR321MSF.ZBTB21.HEK293 166 bp overlap

ZBTB33 3 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 122 bp overlap

ChIP K562 ENCFF875HLX 70 bp overlap

ChIP K562 ENCFF875HLX 419 bp overlap

ZBTB6 1 dataset

ChIP HEK293 GSE76494.ZBTB6.HEK293 119 bp overlap

ZFP37 1 dataset

ChIP HEK293 ENCSR365GRX.ZFP37.HEK293 149 bp overlap

ZFP69B 2 datasets

ChIP HEK293 ENCFF942LFP 232 bp overlap

ChIP HEK293 ENCSR381VYR.ZFP69B.HEK293 226 bp overlap

Motif DE_72h DE_72h-ZIM3_MA1709.2 11 bp overlap

ZNF189 2 datasets

ChIP HEK293 ENCFF638TIB 224 bp overlap

ChIP HEK293 ENCSR163RYW.ZNF189.HEK293 113 bp overlap

ZNF382 1 dataset

Motif DE_72h DE_72h-ZNF382_MA1594.1 24 bp overlap

ZNF384 1 dataset

ChIP HEK293T ENCFF019DZX 88 bp overlap

ZNF394 1 dataset

ChIP HEK293 ENCSR125DNC.ZNF394.HEK293 119 bp overlap

ZNF418 1 dataset

Motif DE_72h DE_72h-ZNF418_MA1980.1 15 bp overlap

ZNF629 3 datasets

ChIP HEK293 ENCFF096ELQ 105 bp overlap

ChIP HEK293 ENCFF096ELQ 282 bp overlap

ChIP HEK293 ENCSR351NON.ZNF629.HEK293 406 bp overlap

ZNF639 1 dataset

ChIP HEK293 ENCSR080CST.ZNF639.HEK293 320 bp overlap

ZNF695 1 dataset

ChIP HEK293T GSE78099.ZNF695.HEK293T 77 bp overlap

ZNF75D 1 dataset

Motif DE_72h DE_72h-ZNF75D_MA1601.2 12 bp overlap