chr21 : 36,994,642 – 36,994,798
156 bp 82 TFs 1 linked gene
This 156 bp open chromatin element is linked to HLCS and is bound by 82 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
HLCS 4.4 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr21:36,989,642 – 36,999,798
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
82 transcription factors
Source
Cell type
AGO1 1 dataset
ChIP Hep-G2 GSE120104.AGO1.Hep-G2 112 bp overlap
AR 1 dataset
ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 101 bp overlap
ASH2L 2 datasets
ChIP H1 ENCFF399KAM 156 bp overlap
ChIP WA01 ENCSR850KIP.ASH2L.WA01 156 bp overlap
ATF2 1 dataset
ChIP WA01 ENCSR000BQU.ATF2.WA01 156 bp overlap
BCL11B 1 dataset
ChIP thymus_CD34neg GSE84677.BCL11B.thymus_CD34neg 134 bp overlap
BCL6 1 dataset
ChIP B-cell_GERMINAL_CENTER GSE43350.BCL6.B-cell_GERMINAL_CENTER 156 bp overlap
BCOR 4 datasets
ChIP B-cell_GERMINAL_CENTER GSE43350.BCOR.B-cell_GERMINAL_CENTER 156 bp overlap
ChIP WA01 GSE104690.BCOR.WA01 156 bp overlap
ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 156 bp overlap
ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 156 bp overlap
BMPR1A 1 dataset
ChIP HUVEC-C GSE60156.BMPR1A.HUVEC-C 137 bp overlap
BRD4 5 datasets
ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 156 bp overlap
ChIP CLL_patient3_4h_CpG GSE109411.BRD4.CLL_patient3_4h_CpG 90 bp overlap
ChIP CLL_patient4 GSE109411.BRD4.CLL_patient4 124 bp overlap
ChIP COLO-741 GSE73319.BRD4.COLO-741 125 bp overlap
ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 156 bp overlap
CEBPB 1 dataset
ChIP WA01 ENCSR000EBV.CEBPB.WA01 112 bp overlap
CHD1 1 dataset
ChIP WA01 ENCSR000AQK.CHD1.WA01 130 bp overlap
CHD2 1 dataset
ChIP WA01 ENCSR000EBT.CHD2.WA01 156 bp overlap
CREB1 5 datasets
ChIP GM23338 ENCFF432ZEW 156 bp overlap
ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 156 bp overlap
ChIP H1 ENCFF955PMP 156 bp overlap
ChIP H1 ENCFF955PMP 61 bp overlap
ChIP WA01 ENCSR000BSN.CREB1.WA01 156 bp overlap
CTBP2 1 dataset
ChIP WA01 ENCSR000EUO.CTBP2.WA01 156 bp overlap
CTCF 18 datasets
ChIP DOHH2 ENCFF637WNW 59 bp overlap
ChIP GM04648 GSE148179.CTCF.GM04648 126 bp overlap
ChIP GM06077 GSE148179.CTCF.GM06077 109 bp overlap
ChIP GP5D GSE51234.CTCF.GP5D 140 bp overlap
ChIP HCT-116 GSE131606.CTCF.HCT-116 92 bp overlap
ChIP HFFc6 ENCFF005CJI 116 bp overlap
ChIP MDA-MB-157 GSE116868.CTCF.MDA-MB-157 156 bp overlap
ChIP OCI-LY7 ENCFF086AXQ 68 bp overlap
ChIP PC-3 ENCFF487TUI 55 bp overlap
ChIP RWPE2 ENCFF911IEE 114 bp overlap
ChIP SU-DHL-6 ENCFF116KKR 86 bp overlap
ChIP WA01 ENCSR000BNH.CTCF.WA01 92 bp overlap
ChIP epithelial cell of prostate ENCFF086GTI 156 bp overlap
ChIP epithelial_kidney ENCSR000DVH.CTCF.epithelial_kidney 101 bp overlap
ChIP lung_left_upper-lobe ENCSR027FSZ.CTCF.lung_left_upper-lobe 156 bp overlap
ChIP neuron_bipolar_doxy_4d ENCSR619IUE.CTCF.neuron_bipolar_doxy_4d 96 bp overlap
ChIP placenta ENCFF029PHY 70 bp overlap
ChIP prostate_epithelial ENCSR196HOM.CTCF.prostate_epithelial 131 bp overlap
CTCFL 1 dataset
ChIP delta-47 GSE70764.CTCFL.delta-47 156 bp overlap
Cebpa 2 datasets
ChIP BLaER1 ENCFF031ISE 156 bp overlap
ChIP BLaER1 ENCFF364PUR 156 bp overlap
E2F6 2 datasets
ChIP H1 ENCFF785DWK 156 bp overlap
ChIP WA01 ENCSR000BSI.E2F6.WA01 156 bp overlap
EP300 1 dataset
ChIP WA01 ENCSR000BKK.EP300.WA01 126 bp overlap
ESR1 1 dataset
ChIP breast_tumor_Male_21 GSE104399.ESR1.breast_tumor_Male_21 156 bp overlap
ETS1 10 datasets
ChIP GM23338 ENCFF701IZH 156 bp overlap
ChIP HUVEC-C GSE109625.ETS1.HUVEC-C 103 bp overlap
ChIP HUVEC-C GSE93030.ETS1.HUVEC-C 103 bp overlap
ChIP HUVEC-C_1h GSE93030.ETS1.HUVEC-C_1h 146 bp overlap
ChIP HUVEC-C_4h GSE93030.ETS1.HUVEC-C_4h 156 bp overlap
ChIP HUVEC-C_VEGF_1H GSE41166.ETS1.HUVEC-C_VEGF_1H 156 bp overlap
ChIP HUVEC-C_VEGF_1h GSE109625.ETS1.HUVEC-C_VEGF_1h 146 bp overlap
ChIP HUVEC-C_VEGF_4H GSE41166.ETS1.HUVEC-C_VEGF_4H 156 bp overlap
ChIP HUVEC-C_VEGF_4h GSE109625.ETS1.HUVEC-C_VEGF_4h 156 bp overlap
ChIP hESC ENCSR534VHI.ETS1.hESC 123 bp overlap
EZH2 1 dataset
ChIP WA01 ENCSR000ASY.EZH2.WA01 156 bp overlap
EZH2_phosphoT487 1 dataset
ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 156 bp overlap
FLI1 2 datasets
ChIP HUVEC-C GSE109695.FLI1.HUVEC-C 156 bp overlap
ChIP TSU-1621MT GSE60477.FLI1.TSU-1621MT 85 bp overlap
FOXA1 1 dataset
ChIP LS180 GSE140533.FOXA1.LS180 70 bp overlap
GABPA 2 datasets
ChIP H1 ENCFF739QFD 156 bp overlap
ChIP WA01 ENCSR000BIW.GABPA.WA01 149 bp overlap
GATAD2B 1 dataset
ChIP GM12878 ENCSR828NCB.GATAD2B.GM12878 156 bp overlap
GTF3C2 1 dataset
ChIP H9 GSE94418.GTF3C2.H9 128 bp overlap
HDAC2 1 dataset
ChIP WA01 ENCSR000AVB.HDAC2.WA01 140 bp overlap
HEXIM1 1 dataset
ChIP HCT-116 GSE72622.HEXIM1.HCT-116 119 bp overlap
HIF1A 1 dataset
ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 142 bp overlap
JUN 2 datasets
ChIP DE_D2 S02-DE-d2-JUN-exp1 156 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 156 bp overlap
JUND 2 datasets
ChIP WA01 ENCSR000EBZ.JUND.WA01 121 bp overlap
ChIP WA01 ENCSR000BKP.JUND.WA01 106 bp overlap
KDM1A 1 dataset
ChIP H1 ENCFF696SGD 145 bp overlap
KDM4A 1 dataset
ChIP WA01 ENCSR000AVC.KDM4A.WA01 156 bp overlap
KMT2A 2 datasets
ChIP CCRF-CEM GSE83671.KMT2A.CCRF-CEM 156 bp overlap
ChIP blood_cord GSE83671.KMT2A.blood_cord 156 bp overlap
MAF 1 dataset
ChIP CD4_Th1 GSE72266.MAF.CD4_Th1 148 bp overlap
MAF1 1 dataset
ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 79 bp overlap
MAX 1 dataset
ChIP H1 ENCFF914VQY 156 bp overlap
MED26 1 dataset
ChIP HEK293T GSE121024.MED26.HEK293T 87 bp overlap
NANOG 3 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 156 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 98 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 101 bp overlap
NR3C1 1 dataset
ChIP breast_tumor_Male_21 GSE104399.NR3C1.breast_tumor_Male_21 156 bp overlap
NUTM1 1 dataset
ChIP embryonic-kidney_induced GSE133122.NUTM1.embryonic-kidney_induced 156 bp overlap
OGG1 2 datasets
ChIP HEK293 GSE89017.OGG1.HEK293 156 bp overlap
ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 156 bp overlap
PAX5 2 datasets
ChIP GM12878 ENCSR000BHD.PAX5.GM12878 156 bp overlap
ChIP GM12878 ENCSR000BHJ.PAX5.GM12878 140 bp overlap
PCGF1 1 dataset
ChIP WA01 GSE104690.PCGF1.WA01 156 bp overlap
PHF8 2 datasets
ChIP H1 ENCFF427UFV 156 bp overlap
ChIP WA01 ENCSR000ATK.PHF8.WA01 156 bp overlap
POLR2A 3 datasets
ChIP GM23338 ENCFF450WCS 156 bp overlap
ChIP GM23338 ENCFF450WCS 143 bp overlap
ChIP H1 ENCFF566JSR 156 bp overlap
POU5F1 3 datasets
ChIP BG03 GSE21614.POU5F1.BG03 119 bp overlap
ChIP DE_D1 DED1-OCT4_Batch_II 156 bp overlap
ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 96 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 152 bp overlap
RBBP5 1 dataset
ChIP WA01 ENCSR000AQC.RBBP5.WA01 156 bp overlap
RBPJ 1 dataset
ChIP SCC_0h GSE156486.RBPJ.SCC_0h 156 bp overlap
REST 3 datasets
ChIP CD4 GSE49570.REST.CD4 156 bp overlap
ChIP H1 ENCFF429RUE 156 bp overlap
ChIP WA01 ENCSR000BHM.REST.WA01 156 bp overlap
RNF2 2 datasets
ChIP WA09 GSE105028.RNF2.WA09 156 bp overlap
ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 156 bp overlap
RUNX1 3 datasets
ChIP AML_Blast GSE60130.RUNX1.AML_Blast 114 bp overlap
ChIP CD34 GSE64862.RUNX1.CD34 114 bp overlap
ChIP Jurkat GSE85524.RUNX1.Jurkat 127 bp overlap
SALL3 1 dataset
ChIP hiPSC GSE104863.SALL3.hiPSC 156 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 156 bp overlap
SMAD3 2 datasets
ChIP HCC1954 GSE104760.SMAD3.HCC1954 156 bp overlap
ChIP HCC1954_TGFb GSE104760.SMAD3.HCC1954_TGFb 63 bp overlap
SMC1 1 dataset
ChIP DKO GSE131606.SMC1.DKO 97 bp overlap
SMC3 1 dataset
ChIP GP5D GSE51234.SMC3.GP5D 151 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 108 bp overlap
SP1 1 dataset
ChIP WA01 ENCSR000BIR.SP1.WA01 156 bp overlap
SP4 1 dataset
ChIP WA01 ENCSR000BQV.SP4.WA01 129 bp overlap
SPI1 1 dataset
ChIP macrophage_IFNG GSE47188.SPI1.macrophage_IFNG 69 bp overlap
SREBP2 1 dataset
ChIP HCC70 GSE126380.SREBP2.HCC70 138 bp overlap
STAT1 1 dataset
ChIP CD14_LPS GSE43036.STAT1.CD14_LPS 104 bp overlap
STAT3 1 dataset
ChIP WA01 ERP004237.STAT3.WA01 57 bp overlap
TAF1 2 datasets
ChIP H1 ENCFF478SZO 156 bp overlap
ChIP WA01 ENCSR000BHO.TAF1.WA01 156 bp overlap
TBP 2 datasets
ChIP H1 ENCFF859IIO 156 bp overlap
ChIP WA01 ENCSR000ECB.TBP.WA01 156 bp overlap
TBX21 1 dataset
ChIP CD4_Th1 GSE62482.TBX21.CD4_Th1 96 bp overlap
TCF12 2 datasets
ChIP GM12878 ENCSR000BGZ.TCF12.GM12878 88 bp overlap
ChIP WA01 ENCSR000BIT.TCF12.WA01 123 bp overlap
TEAD4 1 dataset
ChIP ESC S26-ESC-d0-TEAD4-exp1 156 bp overlap
TP63 3 datasets
ChIP breast-organoid GSE113909.TP63.breast-organoid 73 bp overlap
ChIP keratinocyte GSE33571.TP63.keratinocyte 117 bp overlap
ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 139 bp overlap
TRIM25 1 dataset
ChIP BT-549 GSE79588.TRIM25.BT-549 112 bp overlap
TRIM28 1 dataset
ChIP hESC GSE115387.TRIM28.hESC 96 bp overlap
ZBTB33 7 datasets
ChIP GM12878 ENCFF818EFA 137 bp overlap
ChIP GM12878 ENCSR542FLV.ZBTB33.GM12878 105 bp overlap
ChIP K-562 ENCSR876GXA.ZBTB33.K-562 156 bp overlap
ChIP K-562 ENCSR000BKF.ZBTB33.K-562 83 bp overlap
ChIP K562 ENCFF427SDV 156 bp overlap
ChIP K562 ENCFF875HLX 156 bp overlap
ChIP K562 ENCFF911VPU 113 bp overlap
ZBTB48 1 dataset
ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 156 bp overlap
ZNF121 1 dataset
ChIP WTC11 ENCFF291API 115 bp overlap
ZNF143 1 dataset
ChIP WA01 ENCSR000EBW.ZNF143.WA01 57 bp overlap
ZNF3 1 dataset
ChIP K-562 ENCSR195QFV.ZNF3.K-562 116 bp overlap
ZNF563 1 dataset
ChIP HEK293 GSE76494.ZNF563.HEK293 131 bp overlap
ZNF667 1 dataset
ChIP HEK293 GSE76494.ZNF667.HEK293 131 bp overlap
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