chr20:38,607,297–38,607,885

chr20 : 38,607,297 – 38,607,885

588 bp 125 TFs 6 linked genes

This 588 bp open chromatin element is linked to 6 target genes and is bound by 125 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ARHGAP40		5.5 kb	Proximal	Proximity
RALGAPB		134.7 kb	Distal	Multiome
ACTR5		140.9 kb	Distal	Multiome
SNHG11		160.8 kb	Distal	Multiome
SNHG17		172.2 kb	Distal	Multiome
PPP1R16B		198.2 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

125 transcription factors

ALX3 2 datasets

Motif DE_24h DE_24h-ALX3_MA0634.2 6 bp overlap

Motif DE_48h DE_48h-ALX3_MA0634.2 6 bp overlap

ARGFX 2 datasets

Motif DE_24h DE_24h-ARGFX_MA1463.2 8 bp overlap

Motif DE_48h DE_48h-ARGFX_MA1463.2 8 bp overlap

BCL11A 1 dataset

Motif DE_24h DE_24h-BCL11A_MA2324.1 7 bp overlap

BCL6 4 datasets

Motif DE_24h DE_24h-BCL6_MA0463.3 13 bp overlap

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 154 bp overlap

ChIP OCI-Ly1_UV GSE103125.BCL6.OCI-Ly1_UV 144 bp overlap

ChIP SU-DHL-4 GSE119038.BCL6.SU-DHL-4 96 bp overlap

ChIP H-1_DE GSE126661.BRD3.H-1_DE 239 bp overlap

ChIP K-562 ENCSR000ATW.CBX8.K-562 273 bp overlap

CTCF 5 datasets

Motif DE_24h DE_24h-CTCF_MA0139.2 15 bp overlap

Motif DE_24h DE_24h-CTCF_MA1930.2 33 bp overlap

ChIP endodermal cell ENCFF471YCZ 182 bp overlap

ChIP hiPSC_IB7 GSE106870.CTCF.hiPSC_IB7 151 bp overlap

ChIP hiPSC_IIIB12 GSE106870.CTCF.hiPSC_IIIB12 130 bp overlap

CTCF_s 1 dataset

ChIP HeLa-S3_biotin GSE108869.CTCF_s.HeLa-S3_biotin 220 bp overlap

DRGX 2 datasets

Motif DE_24h DE_24h-DRGX_MA1481.2 6 bp overlap

Motif DE_48h DE_48h-DRGX_MA1481.2 6 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 120 bp overlap

ChIP GM12878 ENCSR439WAF.E4F1.GM12878 269 bp overlap

EMX1 2 datasets

Motif DE_24h DE_24h-EMX1_MA0612.3 6 bp overlap

Motif DE_48h DE_48h-EMX1_MA0612.3 6 bp overlap

EMX2 2 datasets

Motif DE_24h DE_24h-EMX2_MA0886.2 6 bp overlap

Motif DE_48h DE_48h-EMX2_MA0886.2 6 bp overlap

Motif DE_24h DE_24h-EN1_MA0027.3 6 bp overlap

Motif DE_48h DE_48h-EN1_MA0027.3 6 bp overlap

EOMES 2 datasets

Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 341 bp overlap

EP300 1 dataset

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 406 bp overlap

ESR1 3 datasets

ChIP MDA-MB-134-VI_ESTROGEN GSE51022.ESR1.MDA-MB-134-VI_ESTROGEN 257 bp overlap

ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 236 bp overlap

ChIP T-47D_Y537S_E2 GSE148277.ESR1.T-47D_Y537S_E2 253 bp overlap

ESX1 2 datasets

Motif DE_24h DE_24h-ESX1_MA0644.3 7 bp overlap

Motif DE_48h DE_48h-ESX1_MA0644.3 7 bp overlap

ETV5::FOXI1 2 datasets

Motif DE_24h DE_24h-ETV5FOXI1_MA1946.2 12 bp overlap

Motif DE_48h DE_48h-ETV5FOXI1_MA1946.2 12 bp overlap

ETV5::FOXO1 2 datasets

Motif DE_24h DE_24h-ETV5FOXO1_MA1947.2 10 bp overlap

Motif DE_48h DE_48h-ETV5FOXO1_MA1947.2 10 bp overlap

EVX1 2 datasets

Motif DE_24h DE_24h-EVX1_MA0887.2 6 bp overlap

Motif DE_48h DE_48h-EVX1_MA0887.2 6 bp overlap

EVX2 2 datasets

Motif DE_24h DE_24h-EVX2_MA0888.2 6 bp overlap

Motif DE_48h DE_48h-EVX2_MA0888.2 6 bp overlap

EZH2 4 datasets

ChIP ProEs_SHCTR GSE59087.EZH2.ProEs_SHCTR 211 bp overlap

ChIP dermal-fibroblast_Untransformed GSE126396.EZH2.dermal-fibroblast_Untransformed 588 bp overlap

ChIP fibroblast of lung ENCFF479BAW 544 bp overlap

ChIP fibroblast_LUNG ENCSR000ARO.EZH2.fibroblast_LUNG 170 bp overlap

FOXA1 1 dataset

ChIP breast-cancer_Veh-2856 GSE128018.FOXA1.breast-cancer_Veh-2856 181 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 358 bp overlap

ChIP DE DE-FOXA2-2 468 bp overlap

FOXO1::ELF1 2 datasets

Motif DE_24h DE_24h-FOXO1ELF1_MA1953.2 13 bp overlap

Motif DE_48h DE_48h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXO1::ELK3 2 datasets

Motif DE_24h DE_24h-FOXO1ELK3_MA1955.2 13 bp overlap

Motif DE_48h DE_48h-FOXO1ELK3_MA1955.2 13 bp overlap

FOXO1::FLI1 2 datasets

Motif DE_24h DE_24h-FOXO1FLI1_MA1956.2 13 bp overlap

Motif DE_48h DE_48h-FOXO1FLI1_MA1956.2 13 bp overlap

GATA2 2 datasets

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 367 bp overlap

ChIP TF1 GSE73207.GATA2.TF1 132 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 306 bp overlap

ChIP DE DE-GATA4-2 588 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 318 bp overlap

ChIP DE DE-GATA6-2 523 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 208 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 341 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 530 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 521 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 571 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 492 bp overlap

GSX1 2 datasets

Motif DE_24h DE_24h-GSX1_MA0892.2 6 bp overlap

Motif DE_48h DE_48h-GSX1_MA0892.2 6 bp overlap

GSX2 2 datasets

Motif DE_24h DE_24h-GSX2_MA0893.3 7 bp overlap

Motif DE_48h DE_48h-GSX2_MA0893.3 7 bp overlap

HNRNPH1 2 datasets

ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 161 bp overlap

ChIP Hep-G2 GSE120104.HNRNPH1.Hep-G2 161 bp overlap

HOXA1 2 datasets

Motif DE_24h DE_24h-HOXA1_MA1495.2 6 bp overlap

Motif DE_48h DE_48h-HOXA1_MA1495.2 6 bp overlap

HOXA10 2 datasets

Motif DE_24h DE_24h-HOXA10_MA0899.2 9 bp overlap

Motif DE_48h DE_48h-HOXA10_MA0899.2 9 bp overlap

HOXA2 2 datasets

Motif DE_24h DE_24h-HOXA2_MA0900.3 6 bp overlap

Motif DE_48h DE_48h-HOXA2_MA0900.3 6 bp overlap

HOXA3 2 datasets

Motif DE_24h DE_24h-HOXA3_MA2119.1 7 bp overlap

Motif DE_48h DE_48h-HOXA3_MA2119.1 7 bp overlap

HOXA5 2 datasets

Motif DE_24h DE_24h-HOXA5_MA0158.2 8 bp overlap

Motif DE_48h DE_48h-HOXA5_MA0158.2 8 bp overlap

HOXA6 2 datasets

Motif DE_24h DE_24h-HOXA6_MA1497.2 7 bp overlap

Motif DE_48h DE_48h-HOXA6_MA1497.2 7 bp overlap

HOXB1 2 datasets

Motif DE_24h DE_24h-HOXB1_MA2093.1 7 bp overlap

Motif DE_48h DE_48h-HOXB1_MA2093.1 7 bp overlap

HOXB2 2 datasets

Motif DE_24h DE_24h-HOXB2_MA0902.3 6 bp overlap

Motif DE_48h DE_48h-HOXB2_MA0902.3 6 bp overlap

HOXB3 2 datasets

Motif DE_24h DE_24h-HOXB3_MA0903.2 6 bp overlap

Motif DE_48h DE_48h-HOXB3_MA0903.2 6 bp overlap

HOXB5 2 datasets

Motif DE_24h DE_24h-HOXB5_MA0904.3 6 bp overlap

Motif DE_48h DE_48h-HOXB5_MA0904.3 6 bp overlap

HOXB6 2 datasets

Motif DE_24h DE_24h-HOXB6_MA1500.2 7 bp overlap

Motif DE_48h DE_48h-HOXB6_MA1500.2 7 bp overlap

HOXB7 2 datasets

Motif DE_24h DE_24h-HOXB7_MA1501.2 7 bp overlap

Motif DE_48h DE_48h-HOXB7_MA1501.2 7 bp overlap

HOXB8 2 datasets

Motif DE_24h DE_24h-HOXB8_MA1502.2 7 bp overlap

Motif DE_48h DE_48h-HOXB8_MA1502.2 7 bp overlap

HOXC8 2 datasets

Motif DE_24h DE_24h-HOXC8_MA1505.2 6 bp overlap

Motif DE_48h DE_48h-HOXC8_MA1505.2 6 bp overlap

HOXD3 2 datasets

Motif DE_24h DE_24h-HOXD3_MA0912.2 8 bp overlap

Motif DE_48h DE_48h-HOXD3_MA0912.2 8 bp overlap

HOXD8 2 datasets

Motif DE_24h DE_24h-HOXD8_MA0910.3 7 bp overlap

Motif DE_48h DE_48h-HOXD8_MA0910.3 7 bp overlap

HOXD9 2 datasets

Motif DE_24h DE_24h-HOXD9_MA0913.3 9 bp overlap

Motif DE_48h DE_48h-HOXD9_MA0913.3 9 bp overlap

Motif DE_24h DE_24h-ISX_MA0654.2 6 bp overlap

Motif DE_48h DE_48h-ISX_MA0654.2 6 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 316 bp overlap

ChIP MDA-BoM-1833 GSE112444.JUN.MDA-BoM-1833 200 bp overlap

KDM4A 1 dataset

ChIP WA01 ENCSR000AVC.KDM4A.WA01 209 bp overlap

LHX5 2 datasets

Motif DE_24h DE_24h-LHX5_MA1519.2 7 bp overlap

Motif DE_48h DE_48h-LHX5_MA1519.2 7 bp overlap

LHX6 2 datasets

Motif DE_24h DE_24h-LHX6_MA0658.2 8 bp overlap

Motif DE_48h DE_48h-LHX6_MA0658.2 8 bp overlap

LMX1A 2 datasets

Motif DE_24h DE_24h-LMX1A_MA0702.3 7 bp overlap

Motif DE_48h DE_48h-LMX1A_MA0702.3 7 bp overlap

LMX1B 2 datasets

Motif DE_24h DE_24h-LMX1B_MA0703.3 8 bp overlap

Motif DE_48h DE_48h-LMX1B_MA0703.3 8 bp overlap

Lhx1 2 datasets

Motif DE_24h DE_24h-Lhx1_MA1518.3 10 bp overlap

Motif DE_48h DE_48h-Lhx1_MA1518.3 10 bp overlap

Lhx4 2 datasets

Motif DE_24h DE_24h-Lhx4_MA0704.2 6 bp overlap

Motif DE_48h DE_48h-Lhx4_MA0704.2 6 bp overlap

Lhx8 2 datasets

Motif DE_24h DE_24h-Lhx8_MA0705.2 6 bp overlap

Motif DE_48h DE_48h-Lhx8_MA0705.2 6 bp overlap

Motif DE_24h DE_24h-MAZ_MA1522.2 8 bp overlap

Motif DE_48h DE_48h-MAZ_MA1522.2 8 bp overlap

MEOX1 2 datasets

Motif DE_24h DE_24h-MEOX1_MA0661.2 7 bp overlap

Motif DE_48h DE_48h-MEOX1_MA0661.2 7 bp overlap

MEOX2 2 datasets

Motif DE_24h DE_24h-MEOX2_MA0706.2 7 bp overlap

Motif DE_48h DE_48h-MEOX2_MA0706.2 7 bp overlap

Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap

MGA::EVX1 1 dataset

Motif DE_48h DE_48h-MGAEVX1_MA1960.2 11 bp overlap

MIXL1 2 datasets

Motif DE_24h DE_24h-MIXL1_MA0662.2 6 bp overlap

Motif DE_48h DE_48h-MIXL1_MA0662.2 6 bp overlap

MNX1 2 datasets

Motif DE_24h DE_24h-MNX1_MA0707.3 6 bp overlap

Motif DE_48h DE_48h-MNX1_MA0707.3 6 bp overlap

NKX6-1 2 datasets

Motif DE_24h DE_24h-NKX6-1_MA0674.2 7 bp overlap

Motif DE_48h DE_48h-NKX6-1_MA0674.2 7 bp overlap

NKX6-2 2 datasets

Motif DE_24h DE_24h-NKX6-2_MA0675.2 6 bp overlap

Motif DE_48h DE_48h-NKX6-2_MA0675.2 6 bp overlap

NOTO 2 datasets

Motif DE_24h DE_24h-NOTO_MA0710.2 7 bp overlap

Motif DE_48h DE_48h-NOTO_MA0710.2 7 bp overlap

Motif DE_24h DE_24h-OSR2_MA1646.2 8 bp overlap

PATZ1 2 datasets

Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap

Motif DE_48h DE_48h-PATZ1_MA1961.2 11 bp overlap

PDX1 2 datasets

Motif DE_24h DE_24h-PDX1_MA0132.3 6 bp overlap

Motif DE_48h DE_48h-PDX1_MA0132.3 6 bp overlap

POU2F1 1 dataset

ChIP 22Rv1_DHT GSE123565.POU2F1.22Rv1_DHT 51 bp overlap

POU5F1 2 datasets

ChIP BG03 GSE21614.POU5F1.BG03 221 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 564 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 540 bp overlap

POU6F1 2 datasets

Motif DE_24h DE_24h-POU6F1_MA0628.2 6 bp overlap

Motif DE_48h DE_48h-POU6F1_MA0628.2 6 bp overlap

PRRX1 2 datasets

Motif DE_24h DE_24h-PRRX1_MA0716.2 6 bp overlap

Motif DE_48h DE_48h-PRRX1_MA0716.2 6 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_24h DE_24h-Pou5f1Sox2_MA0142.1 15 bp overlap

Motif DE_48h DE_48h-RARA_MA0729.1 18 bp overlap

RAX2 2 datasets

Motif DE_24h DE_24h-RAX2_MA0717.2 6 bp overlap

Motif DE_48h DE_48h-RAX2_MA0717.2 6 bp overlap

SHOX 2 datasets

Motif DE_24h DE_24h-SHOX_MA0630.2 6 bp overlap

Motif DE_48h DE_48h-SHOX_MA0630.2 6 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 574 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 575 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 588 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 507 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 470 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 464 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 534 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 437 bp overlap

ChIP HeLa-Kyoto_WAPL_PDS-depleted GSE102884.SMC3.HeLa-Kyoto_WAPL_PDS-depleted 236 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 299 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 541 bp overlap

SUZ12 1 dataset

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 322 bp overlap

Shox2 2 datasets

Motif DE_24h DE_24h-Shox2_MA0720.2 6 bp overlap

Motif DE_48h DE_48h-Shox2_MA0720.2 6 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 314 bp overlap

TBL1X 1 dataset

ChIP HEK293T GSE35197.TBL1X.HEK293T 189 bp overlap

Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap

Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap

Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap

TBX20 2 datasets

Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap

Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap

Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap

Motif DE_48h DE_48h-TBX4_MA0806.1 8 bp overlap

Motif DE_48h DE_48h-TBX5_MA0807.1 8 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 306 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 433 bp overlap

THAP1 2 datasets

Motif DE_24h DE_24h-THAP1_MA0597.3 8 bp overlap

Motif DE_48h DE_48h-THAP1_MA0597.3 8 bp overlap

TLX2 2 datasets

Motif DE_24h DE_24h-TLX2_MA1577.2 6 bp overlap

Motif DE_48h DE_48h-TLX2_MA1577.2 6 bp overlap

Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap

UNCX 2 datasets

Motif DE_24h DE_24h-UNCX_MA0721.2 6 bp overlap

Motif DE_48h DE_48h-UNCX_MA0721.2 6 bp overlap

VAX1 2 datasets

Motif DE_24h DE_24h-VAX1_MA0722.2 7 bp overlap

Motif DE_48h DE_48h-VAX1_MA0722.2 7 bp overlap

VAX2 2 datasets

Motif DE_24h DE_24h-VAX2_MA0723.3 6 bp overlap

Motif DE_48h DE_48h-VAX2_MA0723.3 6 bp overlap

VSX1 2 datasets

Motif DE_24h DE_24h-VSX1_MA0725.2 7 bp overlap

Motif DE_48h DE_48h-VSX1_MA0725.2 7 bp overlap

VSX2 2 datasets

Motif DE_24h DE_24h-VSX2_MA0726.2 7 bp overlap

Motif DE_48h DE_48h-VSX2_MA0726.2 7 bp overlap

ZBTB7A 1 dataset

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 279 bp overlap

ChIP MCF-7 GSE102616.ZFX.MCF-7 420 bp overlap

ZNF148 2 datasets

Motif DE_24h DE_24h-ZNF148_MA1653.2 10 bp overlap

Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap

ZNF16 1 dataset

Motif DE_24h DE_24h-ZNF16_MA1654.2 21 bp overlap

ZNF253 1 dataset

ChIP HepG2 ENCFF422LRI 437 bp overlap

ZNF331 1 dataset

Motif DE_24h DE_24h-ZNF331_MA1726.2 10 bp overlap

ZNF35 1 dataset

ChIP HEK293 GSE76494.ZNF35.HEK293 112 bp overlap

ZNF550 1 dataset

ChIP Hep-G2 ENCSR198BHH.ZNF550.Hep-G2 335 bp overlap

ZNF701 1 dataset

Motif DE_24h DE_24h-ZNF701_MA1987.2 17 bp overlap

ZNF770 1 dataset

Motif DE_48h DE_48h-ZNF770_MA2099.1 8 bp overlap

Zfp335 1 dataset

Motif DE_48h DE_48h-Zfp335_MA2002.2 7 bp overlap

Zic1::Zic2 1 dataset

Motif DE_24h DE_24h-Zic1Zic2_MA1628.2 7 bp overlap

Motif DE_24h DE_24h-Zic3_MA0697.3 7 bp overlap

mix-a 2 datasets

Motif DE_24h DE_24h-mix-a_MA0621.2 7 bp overlap

Motif DE_48h DE_48h-mix-a_MA0621.2 7 bp overlap