This gene is a member of the non-protein-coding multiple snoRNA host gene family. Two snoRNAs are derived from the introns of this host gene. Although many alternative splice variants have been observed, the gene is thought to have no protein-coding potential. [provided by RefSeq, Jul 2008]
Transcription factors with Perturb-seq knockdown data for SNHG11. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = SNHG11 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of SNHG11, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr20:38,165,098–38,165,562 | 281.3 kb | Distal (>10kb) Multiome | 707 | |
| chr20:38,260,290–38,261,046 | 186.0 kb | Distal (>10kb) Multiome | 161 | |
| chr20:38,434,868–38,435,524 | 11.4 kb | Distal (>10kb) Multiome | 1105 | |
| chr20:38,446,498–38,447,092 | 21 bp | At TSS Multiome | 1046 | |
| chr20:38,472,312–38,473,463 | 26.0 kb | Distal (>10kb) Multiome | 898 | |
| chr20:38,607,297–38,607,885 | 160.8 kb | Distal (>10kb) Multiome | 125 | |
| chr20:38,612,897–38,613,663 | 166.4 kb | Distal (>10kb) Multiome | 78 | |
| chr20:38,646,005–38,646,460 | 199.6 kb | Distal (>10kb) Multiome | 567 | |
| chr20:38,673,746–38,675,067 | 227.8 kb | Distal (>10kb) Multiome | 446 | |
| chr20:38,725,938–38,726,412 | 279.3 kb | Distal (>10kb) Multiome | 218 | |
| chr20:38,727,220–38,727,813 | 280.7 kb | Distal (>10kb) Multiome | 231 | |
| chr20:38,730,955–38,731,938 | 284.6 kb | Distal (>10kb) Multiome | 646 |
Genomic view of the SNHG11 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.