chr14:100,372,706–100,373,117

chr14 : 100,372,706 – 100,373,117

411 bp 79 TFs 5 linked genes

This 411 bp open chromatin element is linked to 5 target genes and is bound by 79 transcription factors.

Linked Genes

5 genes

Gene	Expression	Dist. to TSS	Distance	Link type
WARS1		2.3 kb	Proximal	Proximity
WDR25		3.4 kb	Proximal	Proximity
SLC25A29		66.5 kb	Distal	Multiome+HiCAR
YY1		133.8 kb	Distal	Multiome
ENSG00000258982		134.4 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

79 transcription factors

ChIP K-562 ENCSR241LIH.AFF1.K-562 268 bp overlap

ARID1B 1 dataset

ChIP K-562 ENCSR822CCM.ARID1B.K-562 384 bp overlap

ARID2 1 dataset

ChIP Aska-SS_shSSX GSE108025.ARID2.Aska-SS_shSSX 348 bp overlap

ARID3B 1 dataset

ChIP K-562 ENCSR360UHC.ARID3B.K-562 253 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 306 bp overlap

BACH1 1 dataset

ChIP GM12878 ENCSR636MKU.BACH1.GM12878 276 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD3.K-562_iBET-BD2-IFNG 347 bp overlap

BRD4 4 datasets

ChIP K-562_DMSO-IFNG GSE138084.BRD4.K-562_DMSO-IFNG 214 bp overlap

ChIP K-562_iBET-BD2 GSE138084.BRD4.K-562_iBET-BD2 252 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD4.K-562_iBET-BD2-IFNG 300 bp overlap

ChIP K-562_iBET-IFNG GSE138084.BRD4.K-562_iBET-IFNG 209 bp overlap

CEBPB 1 dataset

ChIP K-562 ENCSR000BRQ.CEBPB.K-562 57 bp overlap

ChIP WA01 ENCSR000AQK.CHD1.WA01 272 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 147 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR619IUE.CTCF.neuron_bipolar_doxy_4d 119 bp overlap

ChIP K-562 ENCSR036QIR.E2F3.K-562 181 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 333 bp overlap

EPAS1 1 dataset

ChIP macrophage_HYPO_IL GSE43109.EPAS1.macrophage_HYPO_IL 67 bp overlap

ChIP VCaP GSE49091.ERG.VCaP 188 bp overlap

GATA1 1 dataset

ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 68 bp overlap

GATA2 3 datasets

ChIP K-562 ENCSR000DKA.GATA2.K-562 112 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 107 bp overlap

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 182 bp overlap

GATA3_Nter 1 dataset

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 99 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 330 bp overlap

ChIP DE DE-GATA4-2 411 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 359 bp overlap

ChIP DE DE-GATA6-2 411 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 355 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 298 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 323 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 411 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 409 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 411 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 404 bp overlap

GFI1B 1 dataset

ChIP K-562 ENCSR509GDT.GFI1B.K-562 156 bp overlap

HDAC1 1 dataset

ChIP K562 ENCFF968WBH 184 bp overlap

HDAC2 1 dataset

ChIP K-562 ENCSR000BMG.HDAC2.K-562 119 bp overlap

HDGF 2 datasets

ChIP K-562 ENCSR197ALX.HDGF.K-562 411 bp overlap

ChIP K-562 ENCSR563YDA.HDGF.K-562 348 bp overlap

IKZF1 1 dataset

ChIP K-562 ENCSR395HWC.IKZF1.K-562 304 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 379 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 79 bp overlap

KDM1A 1 dataset

ChIP K-562 GSE117944.KDM1A.K-562 269 bp overlap

KDM5B 1 dataset

ChIP K-562 ENCSR000AQA.KDM5B.K-562 164 bp overlap

KLF17 2 datasets

ChIP HEK293 ENCFF658MHR 263 bp overlap

ChIP HEK293 ENCSR065WUF.KLF17.HEK293 222 bp overlap

ChIP K-562 ENCSR297CGF.KLF6.K-562 332 bp overlap

ChIP CD4_Th1 GSE72266.MAF.CD4_Th1 184 bp overlap

ChIP H1 ENCFF914VQY 328 bp overlap

ChIP K-562 ENCSR000EFV.MAX.K-562 216 bp overlap

ChIP K562 ENCFF524IJO 342 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 259 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 326 bp overlap

MEIS2 2 datasets

ChIP K-562 ENCSR851BNE.MEIS2.K-562 302 bp overlap

ChIP K562 ENCFF320GSD 93 bp overlap

MLLT1 2 datasets

ChIP K-562 ENCSR107GRP.MLLT1.K-562 411 bp overlap

ChIP K-562 ENCSR675LRO.MLLT1.K-562 162 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 133 bp overlap

ChIP NCI-H128 GSE41105.MYC.NCI-H128 251 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 290 bp overlap

NFE2L2 1 dataset

ChIP K-562 ENCSR485GKE.NFE2L2.K-562 115 bp overlap

PBX2 2 datasets

ChIP K-562 ENCSR263DFP.PBX2.K-562 306 bp overlap

ChIP K562 ENCFF286KMN 197 bp overlap

PDX1 3 datasets

ChIP hiPSC GSE125768.PDX1.hiPSC 331 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 275 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 161 bp overlap

PKNOX1 2 datasets

ChIP K-562 ENCSR115SMW.PKNOX1.K-562 192 bp overlap

ChIP K562 ENCFF236IUS 209 bp overlap

ChIP K-562 ENCSR000BQY.PML.K-562 272 bp overlap

POLR2A 14 datasets

ChIP GM12891 ENCFF379FCI 297 bp overlap

ChIP GM18505 ENCFF311CYB 408 bp overlap

ChIP H1 ENCFF566JSR 411 bp overlap

ChIP H1 ENCFF770YBQ 285 bp overlap

ChIP H1 ENCFF770YBQ 349 bp overlap

ChIP HL-60 ENCFF321XKE 411 bp overlap

ChIP K562 ENCFF214YGX 203 bp overlap

ChIP K562 ENCFF214YGX 264 bp overlap

ChIP K562 ENCFF215CWW 179 bp overlap

ChIP K562 ENCFF215CWW 411 bp overlap

ChIP K562 ENCFF514URW 388 bp overlap

ChIP K562 ENCFF757TUO 317 bp overlap

ChIP K562 ENCFF836GHX 398 bp overlap

ChIP K562 ENCFF836GHX 409 bp overlap

ChIP H1 ENCFF429RUE 190 bp overlap

RREB1 1 dataset

ChIP K-562 ENCSR250WFW.RREB1.K-562 231 bp overlap

SMAD1 1 dataset

ChIP K-562 ENCSR038DJJ.SMAD1.K-562 126 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 221 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 411 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 402 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 411 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 399 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 347 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 362 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 411 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 411 bp overlap

SMAD3 1 dataset

ChIP endoderm GSE29422.SMAD3.endoderm 169 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 235 bp overlap

SMARCA4 1 dataset

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 401 bp overlap

SMARCE1 2 datasets

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 179 bp overlap

ChIP K562 ENCFF690CFF 322 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 280 bp overlap

STAT1 1 dataset

ChIP HeLa-S3 ENCSR000EZK.STAT1.HeLa-S3 98 bp overlap

SUPT5H 1 dataset

ChIP K562 ENCFF902PAW 259 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 187 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 232 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 249 bp overlap

TRIM28 1 dataset

ChIP hESC GSE115387.TRIM28.hESC 179 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 155 bp overlap

ChIP HEK293 ENCSR966PJJ.WT1.HEK293 97 bp overlap

ChIP K-562 ENCSR000BMH.YY1.K-562 121 bp overlap

ZBTB11 2 datasets

ChIP K562 ENCFF215OUF 404 bp overlap

ChIP K562 ENCFF215OUF 411 bp overlap

ZBTB17 1 dataset

ChIP HEK293 ENCFF865LIO 370 bp overlap

ZBTB40 1 dataset

ChIP K-562 ENCSR237VLT.ZBTB40.K-562 326 bp overlap

ZBTB48 1 dataset

ChIP HEK293 ENCSR781EQJ.ZBTB48.HEK293 264 bp overlap

ZBTB7A 2 datasets

ChIP K-562 GSE103445.ZBTB7A.K-562 188 bp overlap

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 127 bp overlap

ZFP36 2 datasets

ChIP K-562 ENCSR776CYN.ZFP36.K-562 162 bp overlap

ChIP K562 ENCFF255RZG 297 bp overlap

ChIP HEK293 ENCFF033NQQ 409 bp overlap

ZNF335 2 datasets

ChIP HEK293 ENCFF784SLD 411 bp overlap

ChIP HEK293 ENCSR328SUD.ZNF335.HEK293 411 bp overlap

ZNF394 2 datasets

ChIP HEK293 ENCFF236OPX 317 bp overlap

ChIP HEK293 ENCSR125DNC.ZNF394.HEK293 247 bp overlap

ZNF507 1 dataset

ChIP K-562 ENCSR577KQD.ZNF507.K-562 259 bp overlap

ZNF528 1 dataset

ChIP HEK293 GSE76494.ZNF528.HEK293 192 bp overlap

ZNF548 1 dataset

ChIP HEK293 ENCSR892ZTO.ZNF548.HEK293 263 bp overlap

ZNF592 1 dataset

ChIP K-562 ENCSR249BHQ.ZNF592.K-562 226 bp overlap

ZNF600 1 dataset

ChIP HEK293 ENCFF785JSX 239 bp overlap

ZNF780A 1 dataset

ChIP HEK293T GSE78099.ZNF780A.HEK293T 338 bp overlap