chr12:118,119,571–118,120,301

chr12 : 118,119,571 – 118,120,301

730 bp 62 TFs 7 linked genes

This 730 bp open chromatin element is linked to 7 target genes and is bound by 62 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
VSIG10		16.2 kb	Distal	Multiome
PEBP1		16.4 kb	Distal	Multiome
WSB2		57.3 kb	Distal	Multiome
RFC5		103.0 kb	Distal	Multiome
KSR2		150.8 kb	Distal	Multiome
TAOK3		253.1 kb	Distal	Multiome+HiCAR
SUDS3		256.8 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

62 transcription factors

ChIP MCF-7 GSE48930.AR.MCF-7 158 bp overlap

ChIP WTC11 ENCFF267GQJ 85 bp overlap

ATF2 2 datasets

ChIP H1 ENCFF295GZO 542 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 354 bp overlap

BCOR 5 datasets

ChIP K-562 ENCSR808AKZ.BCOR.K-562 110 bp overlap

ChIP WA01 GSE104690.BCOR.WA01 176 bp overlap

ChIP WA01 GSE104690.BCOR.WA01 157 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 478 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 428 bp overlap

BRD4 3 datasets

ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 180 bp overlap

ChIP K-562_iBET GSE138084.BRD4.K-562_iBET 157 bp overlap

ChIP hESC GSE33281.BRD4.hESC 69 bp overlap

ChIP H1 ENCFF991MKH 268 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 196 bp overlap

CREB1 3 datasets

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 142 bp overlap

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 149 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 145 bp overlap

CTCF 108 datasets

ChIP 22Rv1 ENCFF466OXN 387 bp overlap

ChIP 22Rv1 ENCFF466OXN 590 bp overlap

ChIP 22Rv1 ENCSR857PBV.CTCF.22Rv1 315 bp overlap

ChIP 22Rv1_hydroxy_10nM_4h ENCSR847XGE.CTCF.22Rv1_hydroxy_10nM_4h 231 bp overlap

ChIP 786-O_NORMOXIA GSE78113.CTCF.786-O_NORMOXIA 239 bp overlap

ChIP A-549 ENCSR000AUF.CTCF.A-549 101 bp overlap

ChIP A-549 ENCSR000AUE.CTCF.A-549 255 bp overlap

ChIP A-549 ENCSR000DPF.CTCF.A-549 191 bp overlap

ChIP GM04025_B-lymphocytes GSE111170.CTCF.GM04025_B-lymphocytes 137 bp overlap

ChIP GM04648 GSE148179.CTCF.GM04648 151 bp overlap

ChIP GM09236__B-lymphocytes GSE111170.CTCF.GM09236__B-lymphocytes 143 bp overlap

ChIP GM09237_B-lymphocytes GSE111170.CTCF.GM09237_B-lymphocytes 168 bp overlap

ChIP GM10266 ENCFF241YYF 156 bp overlap

ChIP GM17942 GSE76922.CTCF.GM17942 231 bp overlap

ChIP GM23338 ENCFF531QOI 219 bp overlap

ChIP GM23338 ENCFF772DML 136 bp overlap

ChIP H1 ENCFF230QSV 159 bp overlap

ChIP H1 ENCFF414GZI 196 bp overlap

ChIP H1 ENCFF764RHO 78 bp overlap

ChIP H9 ENCFF152GTF 244 bp overlap

ChIP H9 ENCFF152GTF 461 bp overlap

ChIP HAP1_clone21_CTCF-TSS-CRISPR_1 GSE152721.CTCF.HAP1_clone21_CTCF-TSS-CRISPR_1 179 bp overlap

ChIP HAP1_clone21_CTCF-TSS-CRISPR_2 GSE152721.CTCF.HAP1_clone21_CTCF-TSS-CRISPR_2 201 bp overlap

ChIP HCT-116 ENCSR240PRQ.CTCF.HCT-116 194 bp overlap

ChIP HCT-116 GSE131606.CTCF.HCT-116 186 bp overlap

ChIP HCT-116_RAD21-mAC GSE104888.CTCF.HCT-116_RAD21-mAC 186 bp overlap

ChIP HUES-64_DNMT-KO GSE97394.CTCF.HUES-64_DNMT-KO 149 bp overlap

ChIP HeLa-S3 ENCFF626XQK 196 bp overlap

ChIP HeLa-S3 ENCSR000AOA.CTCF.HeLa-S3 175 bp overlap

ChIP HeLa-S3 ENCSR000DLO.CTCF.HeLa-S3 112 bp overlap

ChIP HeLa-S3 ENCSR000DUB.CTCF.HeLa-S3 102 bp overlap

ChIP HeLa-S3_biotin GSE108869.CTCF.HeLa-S3_biotin 155 bp overlap

ChIP HeLa-S3_shCtrl GSE137848.CTCF.HeLa-S3_shCtrl 167 bp overlap

ChIP HeLa_dC9Sun-D3A_MIR152 GSE107607.CTCF.HeLa_dC9Sun-D3A_MIR152 123 bp overlap

ChIP HepG2 ENCFF127KUP 174 bp overlap

ChIP HepG2 ENCFF757EKU 210 bp overlap

ChIP ID00014 GSE76922.CTCF.ID00014 258 bp overlap

ChIP K-562 ENCSR000AKO.CTCF.K-562 195 bp overlap

ChIP K-562 GSE70764.CTCF.K-562 141 bp overlap

ChIP K-562_RabbitC GSE137216.CTCF.K-562_RabbitC 263 bp overlap

ChIP Kelly_resistant GSE103030.CTCF.Kelly_resistant 142 bp overlap

ChIP Kelly_sensitive GSE103030.CTCF.Kelly_sensitive 112 bp overlap

ChIP Loucy ENCSR464DKE.CTCF.Loucy 173 bp overlap

ChIP MCF-10A GSE98551.CTCF.MCF-10A 178 bp overlap

ChIP MCF-7 ENCFF139NQI 206 bp overlap

ChIP MCF-7 ENCFF198DQX 190 bp overlap

ChIP MCF-7 ENCFF414SZG 159 bp overlap

ChIP MCF-7 ENCFF424NQR 173 bp overlap

ChIP MCF-7 ENCFF494VXA 185 bp overlap

ChIP MCF-7 ENCFF844STM 173 bp overlap

ChIP MCF-7 ENCFF954TUV 173 bp overlap

ChIP MCF-7 ENCSR560BUE.CTCF.MCF-7 214 bp overlap

ChIP MCF-7 ENCSR000DMR.CTCF.MCF-7 124 bp overlap

ChIP MCF-7 ENCSR000DWH.CTCF.MCF-7 131 bp overlap

ChIP MCF-7L_t0 GSE108787.CTCF.MCF-7L_t0 222 bp overlap

ChIP MCF-7L_t16 GSE108787.CTCF.MCF-7L_t16 171 bp overlap

ChIP MCF-7L_t24 GSE108787.CTCF.MCF-7L_t24 186 bp overlap

ChIP MCF-7_NORMOXIA GSE78113.CTCF.MCF-7_NORMOXIA 183 bp overlap

ChIP OCI-Ly3 ENCSR756ZKG.CTCF.OCI-Ly3 291 bp overlap

ChIP OVCAR-8 GSE70764.CTCF.OVCAR-8 163 bp overlap

ChIP PC-3 ENCSR359LOD.CTCF.PC-3 157 bp overlap

ChIP SH-SY5Y GSE101295.CTCF.SH-SY5Y 136 bp overlap

ChIP SK-N-AS GSE101295.CTCF.SK-N-AS 155 bp overlap

ChIP THP-1_Pam3csk-000m-Flavo-000m GSE103477.CTCF.THP-1_Pam3csk-000m-Flavo-000m 199 bp overlap

ChIP THP-1_Pam3csk-000m-Flavo-240m GSE103477.CTCF.THP-1_Pam3csk-000m-Flavo-240m 205 bp overlap

ChIP THP-1_Pam3csk-020m-Flavo-000m GSE103477.CTCF.THP-1_Pam3csk-020m-Flavo-000m 178 bp overlap

ChIP THP-1_Pam3csk-030m-Flavo-000m GSE103477.CTCF.THP-1_Pam3csk-030m-Flavo-000m 155 bp overlap

ChIP THP-1_Pam3csk-060m-Flavo-000m GSE103477.CTCF.THP-1_Pam3csk-060m-Flavo-000m 116 bp overlap

ChIP THP-1_Pam3csk-180m-Flavo-060m GSE103477.CTCF.THP-1_Pam3csk-180m-Flavo-060m 192 bp overlap

ChIP THP-1_Pam3csk-360m-Flavo-240m GSE103477.CTCF.THP-1_Pam3csk-360m-Flavo-240m 199 bp overlap

ChIP THP-1_siCtrl-NS1-Pam3csk-0h GSE103477.CTCF.THP-1_siCtrl-NS1-Pam3csk-0h 252 bp overlap

ChIP THP-1_siCtrl-NS1-Pam3csk-4h GSE103477.CTCF.THP-1_siCtrl-NS1-Pam3csk-4h 146 bp overlap

ChIP THP-1_siCtrl-eGFP-Pam3csk-0h GSE103477.CTCF.THP-1_siCtrl-eGFP-Pam3csk-0h 148 bp overlap

ChIP THP-1_siNIPBL-NS1-Pam3csk-4h GSE103477.CTCF.THP-1_siNIPBL-NS1-Pam3csk-4h 184 bp overlap

ChIP THP-1_siNIPBL-NS1-Pam3csk-7h-Flavo-3h GSE103477.CTCF.THP-1_siNIPBL-NS1-Pam3csk-7h-Flavo-3h 245 bp overlap

ChIP THP-1_siWAPL-eGFP-Pam3csk-4h GSE103477.CTCF.THP-1_siWAPL-eGFP-Pam3csk-4h 156 bp overlap

ChIP VCaP ENCSR265ARE.CTCF.VCaP 295 bp overlap

ChIP WA01 ENCSR000DLK.CTCF.WA01 140 bp overlap

ChIP WA01_NEUR GSE52457.CTCF.WA01_NEUR 161 bp overlap

ChIP WERI-Rb-1 ENCSR000DXW.CTCF.WERI-Rb-1 94 bp overlap

ChIP brain microvascular endothelial cell ENCFF526VHE 207 bp overlap

ChIP cardiac fibroblast ENCFF326EDY 213 bp overlap

ChIP chondrocyte ENCFF134ORZ 447 bp overlap

ChIP delta-47 GSE70764.CTCF.delta-47 93 bp overlap

ChIP endodermal cell ENCFF471YCZ 208 bp overlap

ChIP endothelial_brain-microvascular ENCSR000DTA.CTCF.endothelial_brain-microvascular 160 bp overlap

ChIP fibroblast_CARDIAC ENCSR000DTF.CTCF.fibroblast_CARDIAC 114 bp overlap

ChIP hESC_D0 GSE116862.CTCF.hESC_D0 175 bp overlap

ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 177 bp overlap

ChIP hiPSC_CVI GSE106870.CTCF.hiPSC_CVI 185 bp overlap

ChIP hiPSC_IB12 GSE106870.CTCF.hiPSC_IB12 171 bp overlap

ChIP hiPSC_IB7 GSE106870.CTCF.hiPSC_IB7 182 bp overlap

ChIP hiPSC_IIA11 GSE106870.CTCF.hiPSC_IIA11 188 bp overlap

ChIP hiPSC_IID12 GSE106870.CTCF.hiPSC_IID12 106 bp overlap

ChIP hiPSC_IIIB12 GSE106870.CTCF.hiPSC_IIIB12 144 bp overlap

ChIP hiPSC_IV8 GSE106870.CTCF.hiPSC_IV8 181 bp overlap

ChIP hiPSC_failed-genome-editing GSE106870.CTCF.hiPSC_failed-genome-editing 192 bp overlap

ChIP hiPSC_parental-line GSE106870.CTCF.hiPSC_parental-line 185 bp overlap

ChIP keratinocyte ENCFF046PBT 167 bp overlap

ChIP keratinocyte ENCFF291YDC 167 bp overlap

ChIP keratinocyte ENCSR000DNC.CTCF.keratinocyte 115 bp overlap

ChIP neural ENCSR822CEA.CTCF.neural 300 bp overlap

ChIP neural progenitor cell ENCFF420RBO 284 bp overlap

ChIP neural progenitor cell ENCFF581WPG 338 bp overlap

ChIP neural_progenitor ENCSR125NBL.CTCF.neural_progenitor 256 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR619IUE.CTCF.neuron_bipolar_doxy_4d 108 bp overlap

ChIP osteocyte ENCFF929FPD 312 bp overlap

ChIP type B pancreatic cell ENCFF910FNQ 293 bp overlap

CTNNB1 1 dataset

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 175 bp overlap

EOMES 1 dataset

Motif ES_0h ES_0h-EOMES_MA0800.2 9 bp overlap

ChIP WTC11 ENCFF011YUL 106 bp overlap

ESR1_Y537C 1 dataset

ChIP MCF-7_ESR1_mutant_LTED GSE100074.ESR1_Y537C.MCF-7_ESR1_mutant_LTED 253 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 134 bp overlap

GATA6 1 dataset

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 352 bp overlap

GTF2I 1 dataset

ChIP WTC11 ENCFF255XXZ 174 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 118 bp overlap

HDAC2 2 datasets

ChIP H1 ENCFF353UJQ 428 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 130 bp overlap

HMGXB4 1 dataset

ChIP WTC11 ENCFF962POR 102 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 367 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 484 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 374 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 494 bp overlap

ChIP H1 ENCFF621PNP 241 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 426 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 276 bp overlap

ChIP WA01 ENCSR000BKP.JUND.WA01 100 bp overlap

KDM1A 1 dataset

ChIP H1 ENCFF696SGD 112 bp overlap

ChIP H1 ENCFF854XWE 285 bp overlap

ChIP WTC11 ENCFF223QFY 569 bp overlap

MED1 2 datasets

ChIP MCF-7_SHRARS_E2 GSE60270.MED1.MCF-7_SHRARS_E2 158 bp overlap

ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 396 bp overlap

MEIS1 2 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MGA_MA0801.1 8 bp overlap

MLLT1 1 dataset

ChIP GM12878 ENCSR552XSN.MLLT1.GM12878 81 bp overlap

ChIP K-562 ENCSR411UYA.MTA2.K-562 196 bp overlap

NANOG 5 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 488 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 294 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 569 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 461 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 354 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 234 bp overlap

POLR2H 1 dataset

ChIP K562 ENCFF377NHG 140 bp overlap

POU5F1 7 datasets

ChIP BG03 GSE21614.POU5F1.BG03 153 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 553 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 487 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 297 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 402 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 285 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 457 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 488 bp overlap

RAD21 6 datasets

ChIP H1 ENCFF698EWO 219 bp overlap

ChIP H1 ENCFF967OJF 217 bp overlap

ChIP HepG2 ENCFF360ZSW 165 bp overlap

ChIP WA09 GSE105028.RAD21.WA09 220 bp overlap

ChIP WA09_heat-shock GSE105028.RAD21.WA09_heat-shock 212 bp overlap

ChIP hiPSC_IIIB12 GSE106870.RAD21.hiPSC_IIIB12 143 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 509 bp overlap

SMAD2_3 2 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 338 bp overlap

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 264 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 324 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 321 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 236 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 222 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 264 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 344 bp overlap

SREBF1 1 dataset

Motif ES_0h ES_0h-SREBF1_MA0595.1 10 bp overlap

SREBF2 1 dataset

Motif ES_0h ES_0h-SREBF2_MA0596.1 10 bp overlap

STAG1 2 datasets

ChIP Hep-G2 ENCSR167MTG.STAG1.Hep-G2 138 bp overlap

ChIP HepG2 ENCFF843EBZ 195 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 238 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 221 bp overlap

ChIP H1 ENCFF859IIO 109 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 132 bp overlap

ChIP hESC_10h GSE122298.TBP.hESC_10h 198 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 200 bp overlap

TEAD4 5 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 267 bp overlap

ChIP H1 ENCFF778PAX 60 bp overlap

ChIP HepG2 ENCFF250NXO 198 bp overlap

ChIP WTC11 ENCFF114TZS 165 bp overlap

ChIP hESC GSE99202.TEAD4.hESC 204 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 437 bp overlap

ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 159 bp overlap

ChIP H1 ENCFF524BTL 257 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 240 bp overlap

ZBTB33 2 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 389 bp overlap

ChIP K562 ENCFF875HLX 465 bp overlap

ZMYM3 2 datasets

ChIP HepG2 ENCFF408KTI 275 bp overlap

ChIP K-562 ENCSR102KIN.ZMYM3.K-562 99 bp overlap

ZNF121 1 dataset

ChIP WTC11 ENCFF291API 186 bp overlap

ZNF184 2 datasets

ChIP WTC11 ENCFF352POG 284 bp overlap

ChIP WTC11 ENCFF352POG 497 bp overlap

ZNF416 1 dataset

Motif ES_0h ES_0h-ZNF416_MA1979.2 10 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 297 bp overlap

ZNF501 1 dataset

ChIP Hep-G2 ENCSR227PHM.ZNF501.Hep-G2 136 bp overlap

ZNF512 1 dataset

ChIP K562 ENCFF601EMZ 225 bp overlap

ZNF768 2 datasets

Motif DE_12h DE_12h-ZNF768_MA1731.2 9 bp overlap

Motif ES_0h ES_0h-ZNF768_MA1731.2 9 bp overlap

ZNF770 5 datasets

ChIP HEK293 ENCFF468FCG 105 bp overlap

ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 164 bp overlap

ChIP HEK293 GSE76494.ZNF770.HEK293 113 bp overlap

ChIP Hep-G2 ENCSR510GKB.ZNF770.Hep-G2 277 bp overlap

ChIP HepG2 ENCFF233UVH 187 bp overlap

ZSCAN18 1 dataset

ChIP WTC11 ENCFF867QWX 137 bp overlap