chr11:47,598,993–47,599,885

chr11 : 47,598,993 – 47,599,885

892 bp 67 TFs 10 linked genes

This 892 bp open chromatin element is linked to 10 target genes and is bound by 67 transcription factors.

Linked Genes

10 genes

Gene	Expression	Dist. to TSS	Distance	Link type
C1QTNF4		4.6 kb	Proximal	Proximity
NDUFS3		20.3 kb	Distal	Multiome
KBTBD4		20.4 kb	Distal	Multiome
PTPMT1		33.8 kb	Distal	Multiome
MTCH2		43.2 kb	Distal	Multiome
CELF1		46.2 kb	Distal	Multiome
FNBP4		167.9 kb	Distal	Multiome
PSMC3		172.9 kb	Distal	Multiome
SLC39A13		190.7 kb	Distal	Multiome
NUP160		249.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

67 transcription factors

ARID2 1 dataset

ChIP Aska-SS GSE108025.ARID2.Aska-SS 369 bp overlap

ASCL1 1 dataset

ChIP NCI-H82 GSE69394.ASCL1.NCI-H82 289 bp overlap

ChIP K-562 ENCSR808AKZ.BCOR.K-562 292 bp overlap

ChIP MV4-11_IBET151_500nM GSE120715.BRD3.MV4-11_IBET151_500nM 179 bp overlap

BRD4 2 datasets

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 53 bp overlap

ChIP retina_AB1-FW23 GSE86981.BRD4.retina_AB1-FW23 335 bp overlap

ChIP retina_Hu20 GSE137311.CRX.retina_Hu20 480 bp overlap

ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 506 bp overlap

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 684 bp overlap

CTBP1 1 dataset

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 277 bp overlap

CTCF 2 datasets

ChIP retina_Hu25 GSE137311.CTCF.retina_Hu25 341 bp overlap

ChIP retina_Hu6 GSE137311.CTCF.retina_Hu6 324 bp overlap

ChIP NTERA2 GSE58641.DDX5.NTERA2 133 bp overlap

ChIP HeLa-S3 ENCSR219MKK.DEK.HeLa-S3 113 bp overlap

ChIP HeLa-S3 ENCSR219MKK.DEK.HeLa-S3 112 bp overlap

ChIP K-562 ENCSR219BXP.DPF2.K-562 212 bp overlap

EGR1 6 datasets

ChIP K-562 ENCSR211LTF.EGR1.K-562 418 bp overlap

ChIP K-562 ENCSR024CNP.EGR1.K-562 376 bp overlap

ChIP K-562 ENCSR000BNE.EGR1.K-562 266 bp overlap

ChIP K562 ENCFF006PJY 99 bp overlap

ChIP K562 ENCFF113OPQ 270 bp overlap

ChIP K562 ENCFF895KGN 271 bp overlap

ChIP HEK293 ENCFF336LFH 384 bp overlap

EHMT2 1 dataset

ChIP K-562 ENCSR175EOM.EHMT2.K-562 398 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 235 bp overlap

ESR1 11 datasets

ChIP MCF-7_jc5849 GSE126004.ESR1.MCF-7_jc5849 105 bp overlap

ChIP T-47D GSE148277.ESR1.T-47D 383 bp overlap

ChIP T-47D ENCSR000BKN.ESR1.T-47D 118 bp overlap

ChIP T-47D_D538G_E2 GSE148277.ESR1.T-47D_D538G_E2 428 bp overlap

ChIP T-47D_DMSO GSE148277.ESR1.T-47D_DMSO 237 bp overlap

ChIP T-47D_JC4729 GSE126004.ESR1.T-47D_JC4729 96 bp overlap

ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 160 bp overlap

ChIP T-47D_Y537S_E2 GSE148277.ESR1.T-47D_Y537S_E2 231 bp overlap

ChIP T-47D_siCont-IL6 GSE126004.ESR1.T-47D_siCont-IL6 333 bp overlap

ChIP T-47D_siFOXA1-IL6 GSE126004.ESR1.T-47D_siFOXA1-IL6 354 bp overlap

ChIP ZR751 ERP000783.ESR1.ZR751 207 bp overlap

ESR1_Y537C 1 dataset

ChIP SUM44PE__ESR1_mutant_LTED GSE100074.ESR1_Y537C.SUM44PE__ESR1_mutant_LTED 437 bp overlap

ESR1_Y537N 1 dataset

ChIP MCF-7_dox_E2 GSE94493.ESR1_Y537N.MCF-7_dox_E2 57 bp overlap

ESRRA 1 dataset

ChIP SK-BR-3_HRG GSE81651.ESRRA.SK-BR-3_HRG 375 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 295 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 295 bp overlap

FLI1 3 datasets

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 278 bp overlap

ChIP A-673_D11 GSE129155.FLI1.A-673_D11 277 bp overlap

ChIP A-673_D17 GSE129155.FLI1.A-673_D17 210 bp overlap

FOXA1 5 datasets

ChIP T-47D_E2_TAM ERP000380.FOXA1.T-47D_E2_TAM 203 bp overlap

ChIP T-47D_JC4742 GSE126004.FOXA1.T-47D_JC4742 193 bp overlap

ChIP T-47D_JC4743 GSE126004.FOXA1.T-47D_JC4743 197 bp overlap

ChIP T-47D_JC4748 GSE126004.FOXA1.T-47D_JC4748 250 bp overlap

ChIP ZR751_E2_TAM ERP000380.FOXA1.ZR751_E2_TAM 300 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 437 bp overlap

ChIP DE DE-FOXA2-2 553 bp overlap

GATA3 1 dataset

ChIP T-47D ENCSR000BMX.GATA3.T-47D 240 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 574 bp overlap

ChIP DE DE-GATA4-2 883 bp overlap

GATA6 6 datasets

ChIP DE DE-GATA6-1 583 bp overlap

ChIP DE DE-GATA6-2 850 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 269 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 298 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 634 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 322 bp overlap

GATAD2B 1 dataset

ChIP MCF-7 ENCSR979FQP.GATAD2B.MCF-7 254 bp overlap

HAND2 1 dataset

ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 261 bp overlap

HDAC1 1 dataset

ChIP K-562 ENCSR711VWL.HDAC1.K-562 293 bp overlap

HDAC2 1 dataset

ChIP K-562 ENCSR893WSB.HDAC2.K-562 312 bp overlap

ChIP K-562 ENCSR197ALX.HDGF.K-562 438 bp overlap

KMT2A 1 dataset

ChIP MOLM-13_VTP-d3-180110 GSE127507.KMT2A.MOLM-13_VTP-d3-180110 146 bp overlap

ChIP K-562 ENCSR000EFV.MAX.K-562 106 bp overlap

ChIP K-562 ENCSR990AZC.MCM3.K-562 499 bp overlap

MEF2D 3 datasets

ChIP retina_Hu13 GSE137311.MEF2D.retina_Hu13 254 bp overlap

ChIP retina_Hu21 GSE137311.MEF2D.retina_Hu21 166 bp overlap

ChIP retina_Hu25 GSE137311.MEF2D.retina_Hu25 237 bp overlap

ChIP melanocyte_BRAFV600E GSE50681.MITF.melanocyte_BRAFV600E 210 bp overlap

MRTFB 1 dataset

ChIP A-673-clone-Asp114 GSE92738.MRTFB.A-673-clone-Asp114 393 bp overlap

ChIP CHP-134 GSE129588.MYCN.CHP-134 200 bp overlap

NCOR1 1 dataset

ChIP K-562 ENCSR798ILC.NCOR1.K-562 287 bp overlap

NEUROD1 5 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 325 bp overlap

ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 243 bp overlap

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 470 bp overlap

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 415 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 650 bp overlap

NEUROG2 5 datasets

ChIP MRC-5_NFD_02DPT GSE75910.NEUROG2.MRC-5_NFD_02DPT 289 bp overlap

ChIP MRC-5_NFD_05DPT GSE75910.NEUROG2.MRC-5_NFD_05DPT 209 bp overlap

ChIP MRC-5_NFD_1DPT GSE75910.NEUROG2.MRC-5_NFD_1DPT 224 bp overlap

ChIP MRC-5_N_02DPT GSE75910.NEUROG2.MRC-5_N_02DPT 271 bp overlap

ChIP MRC-5_N_1DPT GSE75910.NEUROG2.MRC-5_N_1DPT 276 bp overlap

NR2F1 1 dataset

ChIP K-562 ENCSR970NKQ.NR2F1.K-562 113 bp overlap

ChIP retina_Hu13 GSE137311.NRL.retina_Hu13 311 bp overlap

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 539 bp overlap

ChIP T-47D_PROG GSE68355.PGR.T-47D_PROG 179 bp overlap

PHOX2B 2 datasets

ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 357 bp overlap

ChIP SK-N-BE2-C GSE94822.PHOX2B.SK-N-BE2-C 173 bp overlap

PRDM1 1 dataset

ChIP HEK293 ENCFF302TBP 421 bp overlap

ChIP retina_Hu22 GSE137311.RORB.retina_Hu22 326 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 270 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 788 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 582 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 521 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 467 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 531 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 374 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 401 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 378 bp overlap

SMAD4 2 datasets

ChIP HGrC1_C134W-TGF_SMAD2-3-KO GSE138496.SMAD4.HGrC1_C134W-TGF_SMAD2-3-KO 146 bp overlap

ChIP endoderm GSE29422.SMAD4.endoderm 187 bp overlap

SMARCA4 1 dataset

ChIP G-401_Dox GSE71504.SMARCA4.G-401_Dox 251 bp overlap

SMARCA5 1 dataset

ChIP K-562 ENCSR895HSJ.SMARCA5.K-562 432 bp overlap

SMARCC1 2 datasets

ChIP G-401_Dox GSE71504.SMARCC1.G-401_Dox 230 bp overlap

ChIP G-401_NoDox GSE71504.SMARCC1.G-401_NoDox 169 bp overlap

SMARCE1 1 dataset

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 285 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 319 bp overlap

STAT3 12 datasets

ChIP T-47D_JC4735 GSE126004.STAT3.T-47D_JC4735 229 bp overlap

ChIP T-47D_JC4737 GSE126004.STAT3.T-47D_JC4737 164 bp overlap

ChIP T-47D_JC4739 GSE126004.STAT3.T-47D_JC4739 264 bp overlap

ChIP T-47D_JC4741 GSE126004.STAT3.T-47D_JC4741 294 bp overlap

ChIP T-47D_JC4751 GSE126004.STAT3.T-47D_JC4751 336 bp overlap

ChIP T-47D_JC4753 GSE126004.STAT3.T-47D_JC4753 428 bp overlap

ChIP T-47D_JC4755 GSE126004.STAT3.T-47D_JC4755 256 bp overlap

ChIP T-47D_JC4757 GSE126004.STAT3.T-47D_JC4757 490 bp overlap

ChIP T-47D_JC5054 GSE126004.STAT3.T-47D_JC5054 758 bp overlap

ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 741 bp overlap

ChIP T-47D_JC5062 GSE126004.STAT3.T-47D_JC5062 188 bp overlap

ChIP T-47D_JC5062 GSE126004.STAT3.T-47D_JC5062 549 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 252 bp overlap

TEAD4 4 datasets

ChIP BE2C GSE84389.TEAD4.BE2C 191 bp overlap

ChIP MCF-7_BLRP_WT_Veh GSE125594.TEAD4.MCF-7_BLRP_WT_Veh 295 bp overlap

ChIP SK-N-BE2 GSE84389.TEAD4.SK-N-BE2 191 bp overlap

ChIP T-47D_Veh GSE125594.TEAD4.T-47D_Veh 227 bp overlap

YY1AP1 1 dataset

ChIP T-47D_Veh GSE125594.YY1AP1.T-47D_Veh 344 bp overlap

ZBTB33 1 dataset

ChIP MCF-7 ENCSR231YFE.ZBTB33.MCF-7 222 bp overlap

ChIP K-562 ENCSR004GKA.ZEB2.K-562 300 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 371 bp overlap

ChIP HEK293 ENCFF033NQQ 147 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 72 bp overlap