chr1:153,745,487–153,745,959

chr1 : 153,745,487 – 153,745,959

472 bp 55 TFs 18 linked genes

This 472 bp open chromatin element is linked to 18 target genes and is bound by 55 transcription factors.

Linked Genes

18 genes

Gene	Expression	Dist. to TSS	Distance	Link type
INTS3		17.6 kb	Distal	Multiome
SLC27A3		29.7 kb	Distal	Multiome
NPR1		67.0 kb	Distal	Multiome+HiCAR
ILF2		74.7 kb	Distal	Multiome+HiCAR
SNAPIN		87.0 kb	Distal	Multiome
ENSG00000272030		111.3 kb	Distal	Multiome
CHTOP		111.6 kb	Distal	Multiome
S100A13		118.2 kb	Distal	Multiome
GATAD2B		177.3 kb	Distal	Multiome
S100A4		200.6 kb	Distal	Multiome
DENND4B		201.1 kb	Distal	Multiome
S100A6		209.4 kb	Distal	Multiome
SLC39A1		217.8 kb	Distal	Multiome
ENSG00000282386		218.7 kb	Distal	Multiome
CREB3L4		222.2 kb	Distal	Multiome
JTB		232.0 kb	Distal	Multiome
RAB13		240.7 kb	Distal	Multiome
RPS27		245.1 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

55 transcription factors

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 472 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 314 bp overlap

BCL11A 2 datasets

ChIP H1 ENCFF833IPY 145 bp overlap

ChIP WA01 ENCSR000BIP.BCL11A.WA01 213 bp overlap

BCOR 4 datasets

ChIP WA01 GSE104690.BCOR.WA01 224 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 202 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 264 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 315 bp overlap

ChIP WA01 ENCSR000EBT.CHD2.WA01 140 bp overlap

CHD7 2 datasets

ChIP H1 ENCFF126NLU 472 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 140 bp overlap

CREB1 3 datasets

ChIP GM23338 ENCFF432ZEW 223 bp overlap

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 216 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 144 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF262VBH 203 bp overlap

ChIP BLaER1 ENCFF335XTP 202 bp overlap

ChIP H1 ENCFF451BLH 242 bp overlap

EP300 2 datasets

ChIP H1 ENCFF927IYK 297 bp overlap

ChIP WA01 ENCSR000BKK.EP300.WA01 318 bp overlap

ETS1 2 datasets

ChIP GM23338 ENCFF701IZH 324 bp overlap

ChIP hESC ENCSR534VHI.ETS1.hESC 281 bp overlap

FLI1 2 datasets

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 252 bp overlap

ChIP A-673_2_KRAB_eSOX2_1 GSE106914.FLI1.A-673_2_KRAB_eSOX2_1 226 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 374 bp overlap

ChIP DE DE-GATA4-2 463 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 350 bp overlap

ChIP DE DE-GATA6-2 472 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 422 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 453 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 354 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 408 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 453 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 417 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 263 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 365 bp overlap

HDAC2 4 datasets

ChIP H1 ENCFF353UJQ 432 bp overlap

ChIP H1 ENCFF939VKA 237 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 250 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 171 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 254 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 386 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 436 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 382 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 377 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 322 bp overlap

ChIP WTC11 ENCFF223QFY 432 bp overlap

MYBL2 2 datasets

ChIP WTC11 ENCFF166TKT 203 bp overlap

ChIP WTC11 ENCFF166TKT 414 bp overlap

NANOG 7 datasets

ChIP GM23338 ENCFF065NZG 288 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 248 bp overlap

ChIP H1 ENCFF747ZPQ 224 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 472 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 195 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 372 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 413 bp overlap

NCAPH2 2 datasets

ChIP RMG-I GSE120058.NCAPH2.RMG-I 176 bp overlap

ChIP RMG-I_ARID1A-KO GSE120058.NCAPH2.RMG-I_ARID1A-KO 400 bp overlap

NIPBL 1 dataset

ChIP WA09 GSE105028.NIPBL.WA09 258 bp overlap

ChIP WTC11 ENCFF634NAO 245 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 254 bp overlap

POLR2A 1 dataset

ChIP GM23338 ENCFF450WCS 374 bp overlap

POU5F1 7 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 452 bp overlap

ChIP GM23338 ENCFF333SNB 285 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 472 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 290 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 226 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 270 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 278 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 413 bp overlap

Prdm14 1 dataset

Motif DE_48h DE_48h-Prdm14_MA1998.2 8 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 281 bp overlap

SMAD2 2 datasets

Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 435 bp overlap

SMAD2-3 4 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 324 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 397 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 389 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 354 bp overlap

SMAD2_3 6 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 331 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 365 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 347 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 376 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 464 bp overlap

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 354 bp overlap

SMARCA4 3 datasets

ChIP WA09 GSE105028.SMARCA4.WA09 258 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 472 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 472 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 472 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 390 bp overlap

SMARCC1 4 datasets

ChIP DE_D1 S15-DE-d1-BAF155-exp1 311 bp overlap

ChIP ESC S25-ESC-d0-BAF155-exp1 399 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 472 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 472 bp overlap

SOX15 1 dataset

Motif DE_48h DE_48h-SOX15_MA1152.2 7 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 203 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 325 bp overlap

ChIP H1 ENCFF263FUH 110 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 330 bp overlap

ChIP WTC11 ENCFF688PEU 359 bp overlap

ChIP WTC11 ENCFF688PEU 404 bp overlap

ChIP WA01 ENCSR000BQV.SP4.WA01 200 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 98 bp overlap

ChIP hESC GSE122298.TBP.hESC 272 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 288 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 309 bp overlap

ChIP NPC GSE154479.TCF3.NPC 354 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 364 bp overlap

TEAD4 1 dataset

ChIP hESC GSE99202.TEAD4.hESC 296 bp overlap

TP53 4 datasets

ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 355 bp overlap

ChIP H9_mesoderm GSE142050.TP53.H9_mesoderm 291 bp overlap

ChIP WTC11 ENCFF359JCU 472 bp overlap

ChIP WTC11 ENCFF359JCU 297 bp overlap

TRIM28 1 dataset

ChIP hESC GSE115387.TRIM28.hESC 249 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 270 bp overlap

ZBTB43 1 dataset

ChIP WTC11 ENCFF058JUB 205 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 280 bp overlap

ZNF281 1 dataset

ChIP WTC11 ENCFF551GAV 353 bp overlap

ZNF398 2 datasets

ChIP BG01V GSE133630.ZNF398.BG01V 258 bp overlap

ChIP H9 GSE133630.ZNF398.H9 299 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 272 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 205 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 191 bp overlap