chr7:27,175,708–27,176,093

chr7 : 27,175,708 – 27,176,093

385 bp 88 TFs 6 linked genes

This 385 bp open chromatin element is linked to 6 target genes and is bound by 88 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000257184		3.9 kb	Proximal	Proximity
HOXA10		4.2 kb	Proximal	Proximity
HOXA9		6.0 kb	Proximal	Proximity
MIR196B		6.1 kb	Proximal	Proximity
HOXA11-AS		8.4 kb	Proximal	Proximity
HOXA11		9.1 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

88 transcription factors

ChIP LNCaP-clone-FGC_DHT-DMSO GSE118247.AR.LNCaP-clone-FGC_DHT-DMSO 132 bp overlap

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 125 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 385 bp overlap

ARID4B 1 dataset

ChIP PC-3 GSE116669.ARID4B.PC-3 276 bp overlap

BCL11A 1 dataset

ChIP HEK293 ENCSR021DJC.BCL11A.HEK293 85 bp overlap

BCL11B 1 dataset

ChIP HEK293 ENCSR770PQN.BCL11B.HEK293 362 bp overlap

BCOR 3 datasets

ChIP WA01 GSE104690.BCOR.WA01 385 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 385 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 385 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 283 bp overlap

BRD4 12 datasets

ChIP CLL_patient2_4h_CpG_BET GSE109411.BRD4.CLL_patient2_4h_CpG_BET 334 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 345 bp overlap

ChIP HCT-15 GSE73319.BRD4.HCT-15 251 bp overlap

ChIP LPS141 GSE111253.BRD4.LPS141 380 bp overlap

ChIP MDA-MB-157 ERP003925.BRD4.MDA-MB-157 279 bp overlap

ChIP OCI-AML3 GSE104745.BRD4.OCI-AML3 385 bp overlap

ChIP OCI-AML3_JQ1_500nM_24h GSE104745.BRD4.OCI-AML3_JQ1_500nM_24h 335 bp overlap

ChIP SW480 GSE73319.BRD4.SW480 217 bp overlap

ChIP T-47D ERP003925.BRD4.T-47D 385 bp overlap

ChIP THP-1_DMSO GSE138084.BRD4.THP-1_DMSO 61 bp overlap

ChIP THP-1_iBET-BD2 GSE138084.BRD4.THP-1_iBET-BD2 385 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 242 bp overlap

CBX8 2 datasets

ChIP H1 ENCFF095JHA 385 bp overlap

ChIP H1 ENCFF095JHA 279 bp overlap

CDK8 2 datasets

ChIP MOLM-14 GSE65138.CDK8.MOLM-14 385 bp overlap

ChIP MOLM-14_IBET GSE65138.CDK8.MOLM-14_IBET 233 bp overlap

CHD1 3 datasets

ChIP WA01 ENCSR000AQK.CHD1.WA01 210 bp overlap

ChIP hMSC-TERT GSE89179.CHD1.hMSC-TERT 385 bp overlap

ChIP hMSC-TERT_osteoblast GSE89179.CHD1.hMSC-TERT_osteoblast 385 bp overlap

CREBBP 1 dataset

ChIP PC-3_GDC-resist GSE147455.CREBBP.PC-3_GDC-resist 61 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 385 bp overlap

ChIP fibroblast_VILLOUS_MESENCHYME ENCSR000DVQ.CTCF.fibroblast_VILLOUS_MESENCHYME 146 bp overlap

CXXC4 1 dataset

ChIP HEK293T GSE42958.CXXC4.HEK293T 207 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 172 bp overlap

ChIP HUVEC-C GSE124891.ERG.HUVEC-C 282 bp overlap

ChIP VCaP_shARID1A GSE110655.ERG.VCaP_shARID1A 244 bp overlap

ETS1 9 datasets

ChIP HUVEC-C GSE41166.ETS1.HUVEC-C 199 bp overlap

ChIP HUVEC-C GSE109625.ETS1.HUVEC-C 187 bp overlap

ChIP HUVEC-C GSE93030.ETS1.HUVEC-C 187 bp overlap

ChIP HUVEC-C_12h GSE93030.ETS1.HUVEC-C_12h 306 bp overlap

ChIP HUVEC-C_4h GSE93030.ETS1.HUVEC-C_4h 135 bp overlap

ChIP HUVEC-C_VEGF_12H GSE41166.ETS1.HUVEC-C_VEGF_12H 306 bp overlap

ChIP HUVEC-C_VEGF_12h GSE109625.ETS1.HUVEC-C_VEGF_12h 306 bp overlap

ChIP HUVEC-C_VEGF_4H GSE41166.ETS1.HUVEC-C_VEGF_4H 115 bp overlap

ChIP HUVEC-C_VEGF_4h GSE109625.ETS1.HUVEC-C_VEGF_4h 135 bp overlap

EZH2 12 datasets

ChIP A-1847 GSE95643.EZH2.A-1847 385 bp overlap

ChIP A-673 ENCSR179SAO.EZH2.A-673 385 bp overlap

ChIP GM23338 ENCFF613YON 385 bp overlap

ChIP GM23338 ENCFF886DXX 138 bp overlap

ChIP GM23338 ENCFF886DXX 140 bp overlap

ChIP H1 ENCFF232NZA 385 bp overlap

ChIP astrocyte ENCFF365JTP 337 bp overlap

ChIP astrocyte ENCFF365JTP 303 bp overlap

ChIP neural ENCSR511CUH.EZH2.neural 385 bp overlap

ChIP neural progenitor cell ENCFF018MKA 385 bp overlap

ChIP neural progenitor cell ENCFF472NFV 385 bp overlap

ChIP neural progenitor cell ENCFF472NFV 385 bp overlap

EZH2_phosphoT487 1 dataset

ChIP GM23248 ENCSR096KPA.EZH2_phosphoT487.GM23248 209 bp overlap

FEZF1 3 datasets

ChIP HEK293 ENCFF528YED 226 bp overlap

ChIP HEK293 ENCSR827NWO.FEZF1.HEK293 385 bp overlap

ChIP HEK293 GSE76494.FEZF1.HEK293 239 bp overlap

FLI1 2 datasets

ChIP HUVEC-C GSE109695.FLI1.HUVEC-C 176 bp overlap

ChIP HUVEC-C_VEGF_12h GSE109625.FLI1.HUVEC-C_VEGF_12h 64 bp overlap

FOXA1 1 dataset

ChIP LS180 GSE140533.FOXA1.LS180 73 bp overlap

FOXA2 1 dataset

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 355 bp overlap

GLI4 2 datasets

ChIP HEK293 ENCFF606COZ 220 bp overlap

ChIP HEK293 ENCSR211PZO.GLI4.HEK293 240 bp overlap

GLIS1 1 dataset

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 68 bp overlap

ChIP HEK293T ENCSR522LDJ.HDGF.HEK293T 160 bp overlap

HIF1A 1 dataset

ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 252 bp overlap

HOXB13 1 dataset

ChIP G-401 GSE65381.HOXB13.G-401 236 bp overlap

IKZF3 1 dataset

ChIP HEK293 ENCSR304AMN.IKZF3.HEK293 101 bp overlap

JMJD1C 1 dataset

ChIP HL-60 GSE63484.JMJD1C.HL-60 200 bp overlap

KDM6B 1 dataset

ChIP CUTLL1 GSE56694.KDM6B.CUTLL1 179 bp overlap

KMT2A 11 datasets

ChIP HEK293T_C-term GSE90762.KMT2A.HEK293T_C-term 385 bp overlap

ChIP HEK293T_C-term_C104 GSE90762.KMT2A.HEK293T_C-term_C104 385 bp overlap

ChIP HEK293T_C-term_shCtrl GSE90762.KMT2A.HEK293T_C-term_shCtrl 385 bp overlap

ChIP HEK293T_C-term_shCtrl_TASP1-KO GSE90762.KMT2A.HEK293T_C-term_shCtrl_TASP1-KO 385 bp overlap

ChIP IMS-M2_DMSO GSE129636.KMT2A.IMS-M2_DMSO 115 bp overlap

ChIP MCF-7_C-term_CX4945 GSE90762.KMT2A.MCF-7_C-term_CX4945 278 bp overlap

ChIP MCF-7_C-term_TTP22 GSE90762.KMT2A.MCF-7_C-term_TTP22 260 bp overlap

ChIP MOLM-13_DMSO-D3-180110 GSE127507.KMT2A.MOLM-13_DMSO-D3-180110 385 bp overlap

ChIP MOLM-13_VTP-d3-180110 GSE127507.KMT2A.MOLM-13_VTP-d3-180110 385 bp overlap

ChIP SHI-1 GSE95511.KMT2A.SHI-1 385 bp overlap

ChIP THP-1 GSE83671.KMT2A.THP-1 385 bp overlap

MED1 3 datasets

ChIP MOLM-14_DHE GSE124963.MED1.MOLM-14_DHE 263 bp overlap

ChIP MOLM-14_Veh GSE124963.MED1.MOLM-14_Veh 92 bp overlap

ChIP MOLM-14_Veh GSE124963.MED1.MOLM-14_Veh 181 bp overlap

ChIP RS4-11_DMSO-D3-180110 GSE127507.MEN1.RS4-11_DMSO-D3-180110 215 bp overlap

MYOCD 1 dataset

ChIP A-549 GSE128921.MYOCD.A-549 323 bp overlap

NCOR1 2 datasets

ChIP LS180 GSE39277.NCOR1.LS180 81 bp overlap

ChIP LS180_125 GSE39277.NCOR1.LS180_125 90 bp overlap

NUTM1 1 dataset

ChIP embryonic-kidney GSE133122.NUTM1.embryonic-kidney 385 bp overlap

OGG1 3 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 262 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 239 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 249 bp overlap

POLR2A 5 datasets

ChIP HeLa-S3 ENCFF224LWS 358 bp overlap

ChIP HeLa-S3 ENCFF224LWS 358 bp overlap

ChIP sigmoid colon ENCFF653CQA 117 bp overlap

ChIP vagina ENCFF384GAB 193 bp overlap

ChIP vagina ENCFF384GAB 246 bp overlap

POU2F1 1 dataset

ChIP T-47D GSE148277.POU2F1.T-47D 158 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 385 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 189 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 326 bp overlap

ChIP 786-O GSE86092.RELA.786-O 275 bp overlap

RNF2 3 datasets

ChIP H1 ENCFF239FFS 385 bp overlap

ChIP HUES-64 GSE104059.RNF2.HUES-64 291 bp overlap

ChIP SYO-1_shCt GSE139053.RNF2.SYO-1_shCt 385 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 385 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 271 bp overlap

ChIP LS180_125 GSE31939.RXR.LS180_125 91 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 385 bp overlap

SCRT1 2 datasets

ChIP HEK293 ENCFF513YVP 231 bp overlap

ChIP HEK293 ENCSR605MGM.SCRT1.HEK293 178 bp overlap

SIN3A 1 dataset

ChIP HUVEC-C GSE103245.SIN3A.HUVEC-C 127 bp overlap

SMARCA4 1 dataset

ChIP 22Rv1 GSE115615.SMARCA4.22Rv1 286 bp overlap

SMARCC1 2 datasets

ChIP SYO-1_shCt GSE139053.SMARCC1.SYO-1_shCt 385 bp overlap

ChIP SYO-1_shRING1A-B GSE139053.SMARCC1.SYO-1_shRING1A-B 303 bp overlap

ChIP HEK293 ENCSR807LQP.SP2.HEK293 219 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 385 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 279 bp overlap

SS18-SSX 1 dataset

ChIP fibroblast_78aa-SSX-Tail GSE139053.SS18-SSX.fibroblast_78aa-SSX-Tail 385 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 192 bp overlap

SUPT16H 1 dataset

ChIP hiF-T GSE98758.SUPT16H.hiF-T 137 bp overlap

SUPT5H 1 dataset

ChIP DLD-1_NELFE-AID GSE144786.SUPT5H.DLD-1_NELFE-AID 68 bp overlap

SUZ12 5 datasets

ChIP H1 ENCFF507HGF 121 bp overlap

ChIP H1 ENCFF881NFR 385 bp overlap

ChIP K-562 ENCSR000AUC.SUZ12.K-562 208 bp overlap

ChIP NT2/D1 ENCFF574SXS 385 bp overlap

ChIP NT2/D1 ENCFF574SXS 181 bp overlap

ChIP breast-organoid_BRCA1-mut GSE113909.TCF7.breast-organoid_BRCA1-mut 334 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 219 bp overlap

ChIP SW480_0h_TNFa GSE102796.TP53.SW480_0h_TNFa 293 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 88 bp overlap

TRIM24 2 datasets

ChIP LNCaP-abl_ETOH GSE69331.TRIM24.LNCaP-abl_ETOH 94 bp overlap

ChIP MOLM-13_IACS-9571 GSE100571.TRIM24.MOLM-13_IACS-9571 182 bp overlap

ZBTB17 1 dataset

ChIP HEK293 ENCFF865LIO 328 bp overlap

ZBTB48 2 datasets

ChIP HEK293 ENCSR781EQJ.ZBTB48.HEK293 73 bp overlap

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 385 bp overlap

ZBTB6 3 datasets

ChIP HEK293 ENCFF881ECZ 268 bp overlap

ChIP HEK293 ENCSR619OUC.ZBTB6.HEK293 167 bp overlap

ChIP HEK293 GSE76494.ZBTB6.HEK293 374 bp overlap

ZBTB8A 2 datasets

ChIP HEK293 ENCFF303WRD 193 bp overlap

ChIP HEK293 ENCSR481FEC.ZBTB8A.HEK293 92 bp overlap

ZFP37 1 dataset

ChIP HEK293 ENCSR365GRX.ZFP37.HEK293 385 bp overlap

ZFP69B 1 dataset

ChIP HEK293T GSE78099.ZFP69B.HEK293T 139 bp overlap

ChIP HEK293T ENCFF402JZW 77 bp overlap

ChIP HEK293T ENCFF402JZW 329 bp overlap

ChIP HEK293T_22Rv1 GSE145160.ZFX.HEK293T_22Rv1 385 bp overlap

ChIP HEK293 ENCFF033NQQ 62 bp overlap

ZMYND8 1 dataset

ChIP HEK293 GSE81696.ZMYND8.HEK293 154 bp overlap

ZNF18 1 dataset

ChIP HEK293 ENCSR977HTH.ZNF18.HEK293 108 bp overlap

ZNF2 2 datasets

ChIP HEK293 ENCSR011CKE.ZNF2.HEK293 81 bp overlap

ChIP HEK293 ENCSR011CKE.ZNF2.HEK293 198 bp overlap

ZNF263 1 dataset

ChIP HEK293T GSE78099.ZNF263.HEK293T 346 bp overlap

ZNF335 1 dataset

ChIP HEK293 ENCFF784SLD 169 bp overlap

ZNF366 2 datasets

ChIP HEK293 ENCFF799ATK 149 bp overlap

ChIP HEK293 ENCSR106EBH.ZNF366.HEK293 168 bp overlap

ZNF394 1 dataset

ChIP HEK293 ENCSR125DNC.ZNF394.HEK293 138 bp overlap

ZNF407 1 dataset

ChIP Hep-G2 ENCSR005WGY.ZNF407.Hep-G2 199 bp overlap

ZNF501 1 dataset

ChIP HEK293 ENCSR461ZJT.ZNF501.HEK293 160 bp overlap

ZNF506 1 dataset

ChIP HEK293T GSE78099.ZNF506.HEK293T 74 bp overlap

ZNF519 1 dataset

ChIP HEK293T GSE78099.ZNF519.HEK293T 86 bp overlap

ZNF534 1 dataset

ChIP HEK293T GSE78099.ZNF534.HEK293T 385 bp overlap

ZNF596 2 datasets

ChIP HEK293 ENCFF854MGB 100 bp overlap

ChIP HEK293 ENCSR344SBD.ZNF596.HEK293 57 bp overlap

ZNF629 1 dataset

ChIP HEK293 ENCSR351NON.ZNF629.HEK293 59 bp overlap

ZNF692 2 datasets

ChIP HEK293 ENCSR418MKG.ZNF692.HEK293 134 bp overlap

ChIP HEK293 ENCSR418MKG.ZNF692.HEK293 140 bp overlap

ZSCAN21 1 dataset

ChIP HEK293 ENCSR253CKN.ZSCAN21.HEK293 58 bp overlap

ZSCAN4 1 dataset

ChIP HEK293 ENCSR211GNP.ZSCAN4.HEK293 213 bp overlap

ChIP HEK293 ENCFF835SGA 239 bp overlap