chr6:24,630,916–24,631,933

chr6 : 24,630,916 – 24,631,933

1,017 bp 80 TFs 7 linked genes

This 1.0 kb open chromatin element is linked to 7 target genes and is bound by 80 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
TDP2		35.5 kb	Distal	Multiome
ACOT13		35.7 kb	Distal	Multiome
C6orf62		89.4 kb	Distal	Multiome
ALDH5A1		136.2 kb	Distal	Multiome
GPLD1		136.2 kb	Distal	Multiome
GMNN		143.5 kb	Distal	Multiome
MRS2		228.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

80 transcription factors

ChIP VCaP_DHAT_18H GSE28950.AR.VCaP_DHAT_18H 185 bp overlap

ChIP VCaP_DHAT_2H GSE28950.AR.VCaP_DHAT_2H 179 bp overlap

ChIP VCaP_R1881_30M GSE84432.AR.VCaP_R1881_30M 243 bp overlap

ChIP VCaP_R1881_4H GSE84432.AR.VCaP_R1881_4H 216 bp overlap

ChIP prostate GSE56288.AR.prostate 152 bp overlap

ChIP K-562 ENCSR782WRO.BMI1.K-562 223 bp overlap

ChIP K-562_IBET151_50nM GSE120715.BRD2.K-562_IBET151_50nM 141 bp overlap

BRD4 2 datasets

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 190 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 238 bp overlap

ChIP K-562 ENCSR000ATU.CBX2.K-562 1017 bp overlap

ChIP K-562 ENCSR000ATW.CBX8.K-562 1017 bp overlap

ChIP SK-N-SH ENCSR274SLQ.CHD2.SK-N-SH 115 bp overlap

COMMD3-BMI1,BMI1 1 dataset

ChIP K562 ENCFF139VAJ 305 bp overlap

ChIP anterior-temporal-cortex_fetal GSE116825.CTCF.anterior-temporal-cortex_fetal 154 bp overlap

EOMES 2 datasets

ChIP hESC GSE26097.EOMES.hESC 337 bp overlap

ChIP hESC GSE26097.EOMES.hESC 312 bp overlap

EP300 1 dataset

ChIP SK-N-SH ENCSR000EHV.EP300.SK-N-SH 99 bp overlap

ChIP aortic-endothelial-cell_D5 GSE139377.ERG.aortic-endothelial-cell_D5 141 bp overlap

ESRRG 1 dataset

ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 302 bp overlap

EWSR1-FLI1 3 datasets

Motif DE_36h DE_36h-EWSR1-FLI1_MA0149.1 18 bp overlap

Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap

Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap

ChIP DND41 ENCSR000ASW.EZH2.DND41 115 bp overlap

Elf5 3 datasets

Motif DE_36h DE_36h-Elf5_MA0136.4 8 bp overlap

Motif DE_48h DE_48h-Elf5_MA0136.4 8 bp overlap

Motif DE_72h DE_72h-Elf5_MA0136.4 8 bp overlap

FOXA1 1 dataset

ChIP VCaP_DHT24H GSE58428.FOXA1.VCaP_DHT24H 325 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 876 bp overlap

ChIP DE DE-FOXA2-2 736 bp overlap

GABPA 1 dataset

ChIP VCaP_R1881 GSE49091.GABPA.VCaP_R1881 140 bp overlap

GATA1 1 dataset

ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 95 bp overlap

GATA1::TAL1 4 datasets

Motif DE_36h DE_36h-GATA1TAL1_MA0140.3 17 bp overlap

Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap

Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap

Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap

GATA2 9 datasets

Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap

Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap

Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap

Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap

ChIP SH-SY5Y ENCFF485YIB 338 bp overlap

ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 276 bp overlap

ChIP SK-N-SH ENCFF764OZD 303 bp overlap

ChIP SK-N-SH ENCSR706VOO.GATA2.SK-N-SH 238 bp overlap

ChIP TF1 GSE73207.GATA2.TF1 211 bp overlap

GATA3 1 dataset

ChIP Kelly GSE65664.GATA3.Kelly 58 bp overlap

GATA4 8 datasets

ChIP DE DE-GATA4-1 988 bp overlap

ChIP DE DE-GATA4-2 1017 bp overlap

Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 682 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 257 bp overlap

GATA5 4 datasets

Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap

Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap

GATA6 16 datasets

ChIP DE DE-GATA6-1 831 bp overlap

ChIP DE DE-GATA6-2 918 bp overlap

Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 751 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 797 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 772 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 997 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 910 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 773 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 781 bp overlap

ChIP foregut GSE117136.GATA6.foregut 390 bp overlap

ChIP foregut GSE117136.GATA6.foregut 319 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 797 bp overlap

Gata3 4 datasets

Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

HAND2 3 datasets

ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 323 bp overlap

ChIP Kelly GSE94822.HAND2.Kelly 356 bp overlap

ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 214 bp overlap

HOXB13 4 datasets

ChIP prostate_2483 GSE130408.HOXB13.prostate_2483 148 bp overlap

ChIP prostate_2484 GSE130408.HOXB13.prostate_2484 210 bp overlap

ChIP prostate_P19 GSE130408.HOXB13.prostate_P19 341 bp overlap

ChIP prostate_P27_T GSE130408.HOXB13.prostate_P27_T 189 bp overlap

Hic1 3 datasets

Motif DE_36h DE_36h-Hic1_MA0739.2 8 bp overlap

Motif DE_48h DE_48h-Hic1_MA0739.2 8 bp overlap

Motif DE_60h DE_60h-Hic1_MA0739.2 8 bp overlap

IKZF2 3 datasets

Motif DE_36h DE_36h-IKZF2_MA2326.1 6 bp overlap

Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap

Motif DE_72h DE_72h-IKZF2_MA2326.1 6 bp overlap

ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 249 bp overlap

Motif DE_36h DE_36h-MAZ_MA1522.2 8 bp overlap

Motif DE_48h DE_48h-MAZ_MA1522.2 8 bp overlap

Motif DE_72h DE_72h-MAZ_MA1522.2 8 bp overlap

ChIP Kelly GSE94822.MYCN.Kelly 170 bp overlap

MZF1 3 datasets

Motif DE_36h DE_36h-MZF1_MA0056.3 8 bp overlap

Motif DE_48h DE_48h-MZF1_MA0056.3 8 bp overlap

Motif DE_72h DE_72h-MZF1_MA0056.3 8 bp overlap

Mecom 4 datasets

Motif DE_36h DE_36h-Mecom_MA0029.2 11 bp overlap

Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap

Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap

Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap

NFKB1 4 datasets

Motif DE_36h DE_36h-NFKB1_MA0105.4 13 bp overlap

Motif DE_48h DE_48h-NFKB1_MA0105.4 13 bp overlap

Motif DE_72h DE_72h-NFKB1_MA0105.4 13 bp overlap

ChIP L1236 GSE63736.NFKB1.L1236 185 bp overlap

NFKB2 4 datasets

Motif DE_36h DE_36h-NFKB2_MA0778.2 11 bp overlap

Motif DE_48h DE_48h-NFKB2_MA0778.2 11 bp overlap

Motif DE_72h DE_72h-NFKB2_MA0778.2 11 bp overlap

ChIP L1236 GSE63736.NFKB2.L1236 116 bp overlap

NFYA 2 datasets

Motif DE_36h DE_36h-NFYA_MA0060.4 8 bp overlap

Motif DE_48h DE_48h-NFYA_MA0060.4 8 bp overlap

NOTCH3 1 dataset

ChIP TALL-1_GSI GSE104261.NOTCH3.TALL-1_GSI 178 bp overlap

PHOX2B 2 datasets

ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 328 bp overlap

ChIP SK-N-BE2-C GSE94822.PHOX2B.SK-N-BE2-C 209 bp overlap

PITX3 1 dataset

ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 308 bp overlap

RBPJ 2 datasets

Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap

Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap

RCOR1 1 dataset

ChIP SK-N-SH ENCSR009TKN.RCOR1.SK-N-SH 258 bp overlap

Motif DE_36h DE_36h-REL_MA0101.1 10 bp overlap

Motif DE_48h DE_48h-REL_MA0101.1 10 bp overlap

Motif DE_72h DE_72h-REL_MA0101.1 10 bp overlap

RELA 5 datasets

Motif DE_36h DE_36h-RELA_MA0107.1 10 bp overlap

Motif DE_48h DE_48h-RELA_MA0107.1 10 bp overlap

Motif DE_72h DE_72h-RELA_MA0107.1 10 bp overlap

ChIP LNCaP_SIFOXA1_TNFA GSE83860.RELA.LNCaP_SIFOXA1_TNFA 170 bp overlap

ChIP SW480_16h_TNFa GSE102796.RELA.SW480_16h_TNFa 155 bp overlap

RNF2 5 datasets

ChIP K-562 ENCSR820GND.RNF2.K-562 760 bp overlap

ChIP K-562 ENCSR138FUZ.RNF2.K-562 119 bp overlap

ChIP K-562 ENCSR138FUZ.RNF2.K-562 133 bp overlap

ChIP K-562 ENCSR820GND.RNF2.K-562 142 bp overlap

ChIP K562 ENCFF653BQJ 611 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 854 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 334 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 389 bp overlap

SMARCA4 3 datasets

ChIP K-562 ENCSR643VTW.SMARCA4.K-562 601 bp overlap

ChIP NGP GSE134626.SMARCA4.NGP 140 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 218 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 364 bp overlap

SOX14 4 datasets

Motif DE_36h DE_36h-SOX14_MA1562.2 9 bp overlap

Motif DE_48h DE_48h-SOX14_MA1562.2 9 bp overlap

Motif DE_60h DE_60h-SOX14_MA1562.2 9 bp overlap

Motif DE_72h DE_72h-SOX14_MA1562.2 9 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 711 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 1017 bp overlap

SOX18 4 datasets

Motif DE_36h DE_36h-SOX18_MA1563.2 8 bp overlap

Motif DE_48h DE_48h-SOX18_MA1563.2 8 bp overlap

Motif DE_60h DE_60h-SOX18_MA1563.2 8 bp overlap

Motif DE_72h DE_72h-SOX18_MA1563.2 8 bp overlap

ChIP MRC-5_1DPT GSE75910.SOX4.MRC-5_1DPT 146 bp overlap

SOX9 4 datasets

Motif DE_36h DE_36h-SOX9_MA0077.2 8 bp overlap

Motif DE_48h DE_48h-SOX9_MA0077.2 8 bp overlap

Motif DE_60h DE_60h-SOX9_MA0077.2 8 bp overlap

Motif DE_72h DE_72h-SOX9_MA0077.2 8 bp overlap

Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap

Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

ChIP HEK293 ENCSR468IJT.SP7.HEK293 221 bp overlap

Sox17 4 datasets

Motif DE_36h DE_36h-Sox17_MA0078.3 10 bp overlap

Motif DE_48h DE_48h-Sox17_MA0078.3 10 bp overlap

Motif DE_60h DE_60h-Sox17_MA0078.3 10 bp overlap

Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap

Sox7 4 datasets

Motif DE_36h DE_36h-Sox7_MA2095.1 10 bp overlap

Motif DE_48h DE_48h-Sox7_MA2095.1 10 bp overlap

Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap

Motif DE_72h DE_72h-Sox7_MA2095.1 10 bp overlap

Stat2 4 datasets

Motif DE_36h DE_36h-Stat2_MA1623.2 10 bp overlap

Motif DE_48h DE_48h-Stat2_MA1623.2 10 bp overlap

Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap

Motif DE_72h DE_72h-Stat2_MA1623.2 10 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 206 bp overlap

ChIP hESC GSE122298.TBP.hESC 163 bp overlap

TBX2 2 datasets

ChIP Kelly GSE94822.TBX2.Kelly 194 bp overlap

ChIP SK-N-BE2-C GSE94822.TBX2.SK-N-BE2-C 169 bp overlap

TEAD4 2 datasets

ChIP BE2C GSE84389.TEAD4.BE2C 219 bp overlap

ChIP SK-N-BE2 GSE84389.TEAD4.SK-N-BE2 219 bp overlap

TFAP2B 1 dataset

ChIP SK-N-SH ENCFF869XXQ 329 bp overlap

TRPS1 4 datasets

Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

ZFP36 1 dataset

ChIP K-562 ENCSR776CYN.ZFP36.K-562 113 bp overlap

ZNF148 3 datasets

Motif DE_36h DE_36h-ZNF148_MA1653.2 10 bp overlap

Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap

Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap

ZNF184 4 datasets

Motif DE_36h DE_36h-ZNF184_MA2120.1 13 bp overlap

Motif DE_48h DE_48h-ZNF184_MA2120.1 13 bp overlap

Motif DE_60h DE_60h-ZNF184_MA2120.1 13 bp overlap

Motif DE_72h DE_72h-ZNF184_MA2120.1 13 bp overlap

ZNF418 1 dataset

Motif DE_36h DE_36h-ZNF418_MA1980.1 15 bp overlap

ZNF528 1 dataset

ChIP HEK293 GSE76494.ZNF528.HEK293 301 bp overlap

ZNF530 3 datasets

Motif DE_36h DE_36h-ZNF530_MA1981.2 14 bp overlap

Motif DE_48h DE_48h-ZNF530_MA1981.2 14 bp overlap

Motif DE_72h DE_72h-ZNF530_MA1981.2 14 bp overlap

ZNF558 4 datasets

Motif DE_36h DE_36h-ZNF558_MA2335.1 29 bp overlap

Motif DE_48h DE_48h-ZNF558_MA2335.1 29 bp overlap

Motif DE_60h DE_60h-ZNF558_MA2335.1 29 bp overlap

Motif DE_72h DE_72h-ZNF558_MA2335.1 29 bp overlap

ZNF574 3 datasets

Motif DE_36h DE_36h-ZNF574_MA1982.2 14 bp overlap

Motif DE_48h DE_48h-ZNF574_MA1982.2 14 bp overlap

Motif DE_72h DE_72h-ZNF574_MA1982.2 14 bp overlap

ZNF75A 2 datasets

Motif DE_36h DE_36h-ZNF75A_MA2097.1 12 bp overlap

Motif DE_48h DE_48h-ZNF75A_MA2097.1 12 bp overlap

ZNF75D 3 datasets

Motif DE_36h DE_36h-ZNF75D_MA1601.2 12 bp overlap

Motif DE_48h DE_48h-ZNF75D_MA1601.2 12 bp overlap

Motif DE_72h DE_72h-ZNF75D_MA1601.2 12 bp overlap

ZNF786 1 dataset

ChIP HEK293T GSE78099.ZNF786.HEK293T 256 bp overlap

ZSCAN5C 2 datasets

ChIP HEK293 ENCFF343DTU 152 bp overlap

ChIP HEK293 ENCSR731AGO.ZSCAN5C.HEK293 264 bp overlap