chr5 : 136,381,866 – 136,382,474
608 bp 101 TFs 2 linked genes
This 608 bp open chromatin element is linked to HSPD1P18 and SMAD5 and is bound by 101 transcription factors.
Linked Genes
2 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
HSPD1P18 355 bp At TSS Proximity
SMAD5 249.4 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr5:136,376,866 – 136,387,474
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
101 transcription factors
Source
Cell type
ATF2 1 dataset
ChIP H1 ENCFF295GZO 234 bp overlap
BCOR 3 datasets
ChIP WA01 GSE104690.BCOR.WA01 265 bp overlap
ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 400 bp overlap
ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 226 bp overlap
CDX1 1 dataset
Motif DE_12h DE_12h-CDX1_MA0878.3 10 bp overlap
CHD7 1 dataset
ChIP H1 ENCFF126NLU 150 bp overlap
CTNNB1 1 dataset
ChIP hESC_YAP-_activinA_15h GSE99202.CTNNB1.hESC_YAP-_activinA_15h 430 bp overlap
ELF2 2 datasets
Motif DE_12h DE_12h-ELF2_MA1483.3 10 bp overlap
Motif ES_0h ES_0h-ELF2_MA1483.3 10 bp overlap
ELF4 2 datasets
Motif DE_12h DE_12h-ELF4_MA0641.1 12 bp overlap
Motif ES_0h ES_0h-ELF4_MA0641.1 12 bp overlap
ELK1::HOXA1 2 datasets
Motif DE_12h DE_12h-ELK1HOXA1_MA1931.1 14 bp overlap
Motif ES_0h ES_0h-ELK1HOXA1_MA1931.1 14 bp overlap
ELK3 2 datasets
Motif DE_12h DE_12h-ELK3_MA0759.3 9 bp overlap
Motif ES_0h ES_0h-ELK3_MA0759.3 9 bp overlap
ELK4 2 datasets
Motif DE_12h DE_12h-ELK4_MA0076.3 9 bp overlap
Motif ES_0h ES_0h-ELK4_MA0076.3 9 bp overlap
EP300 3 datasets
ChIP H1 ENCFF927IYK 297 bp overlap
ChIP WA01 ENCSR000BKK.EP300.WA01 331 bp overlap
ChIP hESC GSE17917.EP300.hESC 489 bp overlap
ETS1 2 datasets
ChIP GM23338 ENCFF701IZH 377 bp overlap
ChIP hESC ENCSR534VHI.ETS1.hESC 325 bp overlap
ETV2::DRGX 2 datasets
Motif DE_12h DE_12h-ETV2DRGX_MA1940.2 12 bp overlap
Motif ES_0h ES_0h-ETV2DRGX_MA1940.2 12 bp overlap
ETV5::HOXA2 2 datasets
Motif DE_12h DE_12h-ETV5HOXA2_MA1948.2 12 bp overlap
Motif ES_0h ES_0h-ETV5HOXA2_MA1948.2 12 bp overlap
EWSR1-FLI1 1 dataset
Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap
FLI1::DRGX 2 datasets
Motif DE_12h DE_12h-FLI1DRGX_MA1949.2 14 bp overlap
Motif ES_0h ES_0h-FLI1DRGX_MA1949.2 14 bp overlap
FLI1::FOXI1 1 dataset
Motif DE_12h DE_12h-FLI1FOXI1_MA1950.2 11 bp overlap
FOXA2 2 datasets
Motif DE_12h DE_12h-FOXA2_MA0047.4 8 bp overlap
Motif ES_0h ES_0h-FOXA2_MA0047.4 8 bp overlap
FOXA3 2 datasets
Motif DE_12h DE_12h-FOXA3_MA1683.2 7 bp overlap
Motif ES_0h ES_0h-FOXA3_MA1683.2 7 bp overlap
FOXB1 2 datasets
Motif DE_12h DE_12h-FOXB1_MA0845.1 11 bp overlap
Motif ES_0h ES_0h-FOXB1_MA0845.1 11 bp overlap
FOXC1 2 datasets
Motif DE_12h DE_12h-FOXC1_MA0032.2 11 bp overlap
Motif ES_0h ES_0h-FOXC1_MA0032.2 11 bp overlap
FOXC2 2 datasets
Motif DE_12h DE_12h-FOXC2_MA0846.2 11 bp overlap
Motif ES_0h ES_0h-FOXC2_MA0846.2 11 bp overlap
FOXD3 4 datasets
Motif DE_12h DE_12h-FOXD3_MA0041.3 14 bp overlap
Motif DE_12h DE_12h-FOXD3_MA0041.3 14 bp overlap
Motif ES_0h ES_0h-FOXD3_MA0041.3 14 bp overlap
Motif ES_0h ES_0h-FOXD3_MA0041.3 14 bp overlap
FOXH1 2 datasets
Motif DE_12h DE_12h-FOXH1_MA0479.2 8 bp overlap
Motif ES_0h ES_0h-FOXH1_MA0479.2 8 bp overlap
FOXI1 2 datasets
Motif DE_12h DE_12h-FOXI1_MA0042.2 7 bp overlap
Motif ES_0h ES_0h-FOXI1_MA0042.2 7 bp overlap
FOXP1 3 datasets
Motif DE_12h DE_12h-FOXP1_MA0481.4 7 bp overlap
Motif ES_0h ES_0h-FOXP1_MA0481.4 7 bp overlap
ChIP H9 GSE31006.FOXP1.H9 124 bp overlap
FOXP4 2 datasets
Motif DE_12h DE_12h-FOXP4_MA2117.1 7 bp overlap
Motif ES_0h ES_0h-FOXP4_MA2117.1 7 bp overlap
FOXS1 2 datasets
Motif DE_12h DE_12h-FOXS1_MA2118.1 8 bp overlap
Motif ES_0h ES_0h-FOXS1_MA2118.1 8 bp overlap
Foxl2 2 datasets
Motif DE_12h DE_12h-Foxl2_MA1607.2 10 bp overlap
Motif ES_0h ES_0h-Foxl2_MA1607.2 10 bp overlap
GATA6 2 datasets
ChIP DE_D1 S41-DE-d1-GATA6-exp2 259 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 293 bp overlap
Gfi1B 2 datasets
Motif DE_12h DE_12h-Gfi1B_MA0483.2 10 bp overlap
Motif ES_0h ES_0h-Gfi1B_MA0483.2 10 bp overlap
HOXB2::ELK1 2 datasets
Motif DE_12h DE_12h-HOXB2ELK1_MA1957.1 14 bp overlap
Motif ES_0h ES_0h-HOXB2ELK1_MA1957.1 14 bp overlap
HOXC11 2 datasets
Motif DE_12h DE_12h-HOXC11_MA0651.3 11 bp overlap
Motif ES_0h ES_0h-HOXC11_MA0651.3 11 bp overlap
HOXC12 2 datasets
Motif DE_12h DE_12h-HOXC12_MA0906.2 10 bp overlap
Motif ES_0h ES_0h-HOXC12_MA0906.2 10 bp overlap
HOXD11 2 datasets
Motif DE_12h DE_12h-HOXD11_MA0908.2 9 bp overlap
Motif ES_0h ES_0h-HOXD11_MA0908.2 9 bp overlap
Hoxa11 2 datasets
Motif DE_12h DE_12h-Hoxa11_MA0911.2 9 bp overlap
Motif ES_0h ES_0h-Hoxa11_MA0911.2 9 bp overlap
JUN 6 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 463 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 336 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 524 bp overlap
ChIP ESC S34-ESC-d0-JUN-exp2 377 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 439 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 457 bp overlap
JUND 1 dataset
ChIP H1 ENCFF468JZD 231 bp overlap
KLF4 2 datasets
ChIP WA09 GSE105028.KLF4.WA09 220 bp overlap
ChIP WA09_heat-shock GSE105028.KLF4.WA09_heat-shock 206 bp overlap
MEIS1 2 datasets
Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap
Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap
MORC2 1 dataset
ChIP H9 GSE95374.MORC2.H9 328 bp overlap
NANOG 11 datasets
ChIP GM23338 ENCFF065NZG 82 bp overlap
ChIP GM23338 ENCSR061DGF.NANOG.GM23338 401 bp overlap
ChIP H1 ENCFF747ZPQ 241 bp overlap
ChIP HUES-8 GSE109524.NANOG.HUES-8 608 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 594 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 268 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 608 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 608 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 608 bp overlap
ChIP hESC GSE20650.NANOG.hESC 296 bp overlap
ChIP hESC GSE18292.NANOG.hESC 320 bp overlap
NIPBL 3 datasets
ChIP WA09 GSE105028.NIPBL.WA09 424 bp overlap
ChIP WA09_heat-shock GSE105028.NIPBL.WA09_heat-shock 445 bp overlap
ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 273 bp overlap
NKX2-1 2 datasets
ChIP H9_derived-cIN GSE99937.NKX2-1.H9_derived-cIN 51 bp overlap
ChIP H9_derived-cIN GSE99937.NKX2-1.H9_derived-cIN 64 bp overlap
Nr2e3 2 datasets
Motif DE_12h DE_12h-Nr2e3_MA0164.2 6 bp overlap
Motif ES_0h ES_0h-Nr2e3_MA0164.2 6 bp overlap
OTX2 1 dataset
ChIP WTC11 ENCFF634NAO 245 bp overlap
PCGF1 1 dataset
ChIP WA01 GSE104690.PCGF1.WA01 194 bp overlap
POLR2A 1 dataset
ChIP GM23338 ENCFF450WCS 393 bp overlap
POU2F1 2 datasets
Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap
Motif ES_0h ES_0h-POU2F1_MA0785.2 9 bp overlap
POU2F1::SOX2 4 datasets
Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap
POU2F3 2 datasets
Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap
Motif ES_0h ES_0h-POU2F3_MA0627.3 9 bp overlap
POU3F1 4 datasets
Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap
Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap
Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap
Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap
POU3F4 2 datasets
Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap
Motif ES_0h ES_0h-POU3F4_MA0789.1 9 bp overlap
POU5F1 19 datasets
ChIP BG03 GSE21614.POU5F1.BG03 262 bp overlap
Motif DE_12h DE_12h-POU5F1_MA1115.2 7 bp overlap
Motif DE_12h DE_12h-POU5F1_MA1115.2 7 bp overlap
ChIP DE_D1 DED1-OCT4_Batch_II 373 bp overlap
Motif ES_0h ES_0h-POU5F1_MA1115.2 7 bp overlap
Motif ES_0h ES_0h-POU5F1_MA1115.2 7 bp overlap
ChIP GM23338 ENCFF333SNB 311 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 608 bp overlap
ChIP NCCIT GSE36134.POU5F1.NCCIT 328 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 608 bp overlap
ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 270 bp overlap
ChIP WA09 GSE105028.POU5F1.WA09 426 bp overlap
ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 428 bp overlap
ChIP hESC ENCSR264RJX.POU5F1.hESC 312 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 452 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 608 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 371 bp overlap
ChIP hiPSC GSE149017.POU5F1.hiPSC 168 bp overlap
ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 397 bp overlap
POU5F1B 2 datasets
Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap
Motif ES_0h ES_0h-POU5F1B_MA0792.1 9 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 315 bp overlap
PPARA::RXRA 1 dataset
Motif DE_12h DE_12h-PPARARXRA_MA1148.2 17 bp overlap
PRDM1 3 datasets
Motif DE_12h DE_12h-PRDM1_MA0508.4 7 bp overlap
Motif ES_0h ES_0h-PRDM1_MA0508.4 7 bp overlap
Motif ES_0h ES_0h-PRDM1_MA0508.4 7 bp overlap
PRDM14 3 datasets
ChIP hESC GSE22767.PRDM14.hESC 597 bp overlap
ChIP hESC GSE138674.PRDM14.hESC 313 bp overlap
ChIP primordial-germ-cell-like-cell GSE138674.PRDM14.primordial-germ-cell-like-cell 171 bp overlap
PRDM9 1 dataset
Motif DE_12h DE_12h-PRDM9_MA1723.2 20 bp overlap
Pou5f1::Sox2 4 datasets
Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap
RELB 1 dataset
Motif DE_12h DE_12h-RELB_MA1117.2 7 bp overlap
RNF2 1 dataset
ChIP WA09 GSE105028.RNF2.WA09 351 bp overlap
SMAD2 1 dataset
ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 352 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 361 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 402 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 471 bp overlap
SMAD2_3 6 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 608 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 435 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 502 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 439 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 340 bp overlap
ChIP ESC S33-ESC-d0-SMAD2_3-exp2 332 bp overlap
SMAD3 1 dataset
ChIP BG03 GSE21614.SMAD3.BG03 249 bp overlap
SMARCA4 3 datasets
ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 215 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 608 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 608 bp overlap
SMARCB1 2 datasets
ChIP hiPSC GSE124903.SMARCB1.hiPSC 418 bp overlap
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 403 bp overlap
SMARCC1 5 datasets
ChIP DE_D1 S10-DE-d1-BAF155-exp1 329 bp overlap
ChIP DE_D1 S15-DE-d1-BAF155-exp1 449 bp overlap
ChIP ESC S25-ESC-d0-BAF155-exp1 355 bp overlap
ChIP hiPSC GSE124903.SMARCC1.hiPSC 526 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 371 bp overlap
SOX2 3 datasets
ChIP hESC GSE18292.SOX2.hESC 343 bp overlap
ChIP hESC GSE69479.SOX2.hESC 191 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 482 bp overlap
SP1 2 datasets
ChIP H1 ENCFF263FUH 321 bp overlap
ChIP WA01 ENCSR000BIR.SP1.WA01 402 bp overlap
SP4 1 dataset
ChIP WA01 ENCSR000BQV.SP4.WA01 153 bp overlap
SPDEF 2 datasets
Motif DE_12h DE_12h-SPDEF_MA0686.2 10 bp overlap
Motif ES_0h ES_0h-SPDEF_MA0686.2 10 bp overlap
SPIC 1 dataset
Motif DE_12h DE_12h-SPIC_MA0687.2 13 bp overlap
T 1 dataset
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 155 bp overlap
TCF12 1 dataset
ChIP WA01 ENCSR000BIT.TCF12.WA01 213 bp overlap
TCF3 1 dataset
ChIP NPC GSE154479.TCF3.NPC 367 bp overlap
TCF7L1 2 datasets
Motif DE_12h DE_12h-TCF7L1_MA1421.1 12 bp overlap
Motif ES_0h ES_0h-TCF7L1_MA1421.1 12 bp overlap
TCF7L2 2 datasets
Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap
Motif ES_0h ES_0h-TCF7L2_MA0523.2 9 bp overlap
TEAD1 2 datasets
Motif DE_12h DE_12h-TEAD1_MA0090.4 9 bp overlap
Motif ES_0h ES_0h-TEAD1_MA0090.4 9 bp overlap
TEAD2 1 dataset
Motif DE_12h DE_12h-TEAD2_MA1121.2 7 bp overlap
TEAD4 4 datasets
Motif DE_12h DE_12h-TEAD4_MA0809.3 8 bp overlap
ChIP ESC S26-ESC-d0-TEAD4-exp1 326 bp overlap
ChIP H1 ENCFF778PAX 245 bp overlap
ChIP hESC GSE99202.TEAD4.hESC 185 bp overlap
TFAP2A 1 dataset
ChIP WA09 GSE105081.TFAP2A.WA09 188 bp overlap
TFAP2C 1 dataset
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 333 bp overlap
TGIF1 1 dataset
Motif ES_0h ES_0h-TGIF1_MA0796.1 12 bp overlap
THAP1 1 dataset
Motif DE_12h DE_12h-THAP1_MA0597.3 8 bp overlap
TP53 1 dataset
ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 607 bp overlap
TRIM28 1 dataset
ChIP hESC GSE115387.TRIM28.hESC 208 bp overlap
YY1 1 dataset
ChIP WA01 ENCSR000BKD.YY1.WA01 123 bp overlap
ZBTB18 2 datasets
Motif DE_12h DE_12h-ZBTB18_MA0698.2 11 bp overlap
Motif ES_0h ES_0h-ZBTB18_MA0698.2 11 bp overlap
ZBTB7A 2 datasets
Motif DE_12h DE_12h-ZBTB7A_MA0750.3 9 bp overlap
Motif ES_0h ES_0h-ZBTB7A_MA0750.3 9 bp overlap
ZFP42 2 datasets
Motif DE_12h DE_12h-ZFP42_MA1651.2 13 bp overlap
Motif ES_0h ES_0h-ZFP42_MA1651.2 13 bp overlap
ZMAT4 1 dataset
ChIP WTC11 ENCFF608UXZ 241 bp overlap
ZNF143 1 dataset
ChIP WA09_heat-shock GSE105028.ZNF143.WA09_heat-shock 368 bp overlap
ZNF157 2 datasets
Motif DE_12h DE_12h-ZNF157_MA2331.1 21 bp overlap
Motif ES_0h ES_0h-ZNF157_MA2331.1 21 bp overlap
ZNF207 1 dataset
ChIP WA09 GSE118632.ZNF207.WA09 256 bp overlap
ZNF320 1 dataset
Motif DE_12h DE_12h-ZNF320_MA1976.2 20 bp overlap
ZNF454 2 datasets
Motif DE_12h DE_12h-ZNF454_MA1712.2 17 bp overlap
Motif ES_0h ES_0h-ZNF454_MA1712.2 17 bp overlap
ZNF528 2 datasets
Motif DE_12h DE_12h-ZNF528_MA1597.1 17 bp overlap
Motif ES_0h ES_0h-ZNF528_MA1597.1 17 bp overlap
ZNF768 1 dataset
Motif ES_0h ES_0h-ZNF768_MA1731.2 9 bp overlap
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