chr3 : 148,820,894 – 148,821,376

482 bp 95 TFs 1 linked gene

This 482 bp open chromatin element is linked to CPB1 and is bound by 95 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
CPB1		6.4 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

95 transcription factors

AR 1 dataset

ChIP MCF-7 ERP001226.AR.MCF-7 209 bp overlap

ARID1A 3 datasets

ChIP MCF-7_4-hydroxytamoxifen GSE123284.ARID1A.MCF-7_4-hydroxytamoxifen 411 bp overlap

ChIP MCF-7_Fulvestrant GSE123284.ARID1A.MCF-7_Fulvestrant 392 bp overlap

ChIP MCF-7_JQ1 GSE123284.ARID1A.MCF-7_JQ1 212 bp overlap

BRD4 1 dataset

ChIP T-cell_iBET-BD2 GSE138084.BRD4.T-cell_iBET-BD2 111 bp overlap

CLOCK 1 dataset

ChIP BA40_0 GSE96659.CLOCK.BA40_0 77 bp overlap

CREB1 1 dataset

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 231 bp overlap

CTBP2 1 dataset

ChIP MCF-7 GSE107013.CTBP2.MCF-7 151 bp overlap

CTCF 3 datasets

Motif DE_12h DE_12h-CTCF_MA0139.2 15 bp overlap

Motif DE_12h DE_12h-CTCF_MA1929.2 31 bp overlap

ChIP HeLa-Kyoto_PDS5-depleted GSE102884.CTCF.HeLa-Kyoto_PDS5-depleted 138 bp overlap

DMRTA2 1 dataset

Motif DE_12h DE_12h-DMRTA2_MA1478.2 6 bp overlap

ESR1 16 datasets

ChIP MCF-7 GSE103023.ESR1.MCF-7 223 bp overlap

ChIP MCF-7 GSE41561.ESR1.MCF-7 209 bp overlap

ChIP MCF-7_AZD2014 GSE103023.ESR1.MCF-7_AZD2014 190 bp overlap

ChIP MCF-7_E2 GSE117941.ESR1.MCF-7_E2 200 bp overlap

ChIP MCF-7_G6274 GSE117941.ESR1.MCF-7_G6274 296 bp overlap

ChIP MCF-7_H3B-5942 GSE115607.ESR1.MCF-7_H3B-5942 152 bp overlap

ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 189 bp overlap

ChIP MCF-7_RAD001 GSE103023.ESR1.MCF-7_RAD001 239 bp overlap

ChIP MCF-7_Sat-H3B-6545 GSE115607.ESR1.MCF-7_Sat-H3B-6545 341 bp overlap

ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 185 bp overlap

ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 240 bp overlap

ChIP MCF-7_jc5849 GSE126004.ESR1.MCF-7_jc5849 137 bp overlap

ChIP MCF-7_jc5852 GSE126004.ESR1.MCF-7_jc5852 60 bp overlap

ChIP MCF-7_jc5854 GSE126004.ESR1.MCF-7_jc5854 145 bp overlap

ChIP MCF-7_jc5856 GSE126004.ESR1.MCF-7_jc5856 163 bp overlap

ChIP breast_tumor_Male_19 GSE104399.ESR1.breast_tumor_Male_19 347 bp overlap

ESR1_Y537N 1 dataset

ChIP MCF-7_E2_talen GSE94493.ESR1_Y537N.MCF-7_E2_talen 155 bp overlap

ESR1_Y537S 1 dataset

ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 183 bp overlap

ESRRA 1 dataset

ChIP BT-474_HRG GSE81651.ESRRA.BT-474_HRG 210 bp overlap

EWSR1-FLI1 1 dataset

Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap

FOXA1 19 datasets

ChIP MCF-7 ENCFF465LTH 81 bp overlap

ChIP MCF-7 GSE81714.FOXA1.MCF-7 240 bp overlap

ChIP MCF-7 GSE72249.FOXA1.MCF-7 163 bp overlap

ChIP MCF-7 ERP001226.FOXA1.MCF-7 213 bp overlap

ChIP MCF-7_DEX GSE72249.FOXA1.MCF-7_DEX 163 bp overlap

ChIP MCF-7_E2 GSE72249.FOXA1.MCF-7_E2 237 bp overlap

ChIP MCF-7_E2 GSE23852.FOXA1.MCF-7_E2 126 bp overlap

ChIP MCF-7_E2_TAM ERP000380.FOXA1.MCF-7_E2_TAM 126 bp overlap

ChIP MCF-7_JC4690 GSE126004.FOXA1.MCF-7_JC4690 103 bp overlap

ChIP MCF-7_JC4691 GSE126004.FOXA1.MCF-7_JC4691 180 bp overlap

ChIP MCF-7_JC4697 GSE126004.FOXA1.MCF-7_JC4697 237 bp overlap

ChIP MCF-7_estrogen_ab2 GSE112969.FOXA1.MCF-7_estrogen_ab2 112 bp overlap

ChIP MCF-7_shNR2F2 GSE132432.FOXA1.MCF-7_shNR2F2 269 bp overlap

ChIP MCF-7_vehicle_ab1 GSE112969.FOXA1.MCF-7_vehicle_ab1 131 bp overlap

ChIP MCF-7_vehicle_ab2 GSE112969.FOXA1.MCF-7_vehicle_ab2 77 bp overlap

ChIP breast_tumor_Female_1 GSE104399.FOXA1.breast_tumor_Female_1 203 bp overlap

ChIP breast_tumor_Female_7 GSE104399.FOXA1.breast_tumor_Female_7 91 bp overlap

ChIP breast_tumor_Male_19 GSE104399.FOXA1.breast_tumor_Male_19 209 bp overlap

ChIP primary-breast-cancer_B1_DSG GSE114737.FOXA1.primary-breast-cancer_B1_DSG 292 bp overlap

FOXA2 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 140 bp overlap

GATA3 1 dataset

ChIP MCF-7_sgScr GSE133072.GATA3.MCF-7_sgScr 168 bp overlap

GATA4 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 432 bp overlap

GATA6 5 datasets

ChIP DE_D1 S14-DE-d1-GATA6-exp1 418 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 292 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 423 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 281 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 236 bp overlap

GRHL1 1 dataset

Motif DE_12h DE_12h-GRHL1_MA0647.2 10 bp overlap

GRHL2 2 datasets

Motif DE_12h DE_12h-GRHL2_MA1105.3 8 bp overlap

ChIP MCF-7_E2_45min GSE109820.GRHL2.MCF-7_E2_45min 196 bp overlap

HAND2 1 dataset

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

HDAC2 2 datasets

ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 319 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 123 bp overlap

HNF4A 1 dataset

Motif DE_12h DE_12h-HNF4A_MA0114.5 9 bp overlap

HNF4G 1 dataset

Motif DE_12h DE_12h-HNF4G_MA0484.3 9 bp overlap

Hand1 1 dataset

Motif DE_12h DE_12h-Hand1_MA2123.1 9 bp overlap

KLF14 1 dataset

Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap

KLF5 1 dataset

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

Lhx3 1 dataset

Motif DE_12h DE_12h-Lhx3_MA0135.2 12 bp overlap

MAZ 1 dataset

Motif DE_12h DE_12h-MAZ_MA1522.2 8 bp overlap

MEIS1 1 dataset

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

MYOG 2 datasets

ChIP RH4 GSE83726.MYOG.RH4 292 bp overlap

ChIP RH4_Entinostat-6H GSE116344.MYOG.RH4_Entinostat-6H 205 bp overlap

NANOG 4 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 430 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 117 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 379 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 279 bp overlap

NCOA2 1 dataset

ChIP MCF-7_E2 ERP000901.NCOA2.MCF-7_E2 128 bp overlap

NKX2-1 1 dataset

ChIP NCI-H3122 GSE39998.NKX2-1.NCI-H3122 198 bp overlap

NR1H2::RXRA 1 dataset

Motif DE_12h DE_12h-NR1H2RXRA_MA0115.1 17 bp overlap

NR2F1 1 dataset

Motif DE_12h DE_12h-NR2F1_MA1537.2 13 bp overlap

NR2F2 2 datasets

ChIP MCF-7 ENCFF329FZB 207 bp overlap

ChIP MCF-7 ENCSR000BUY.NR2F2.MCF-7 317 bp overlap

NR2F6 1 dataset

ChIP Hep-G2 ENCSR518WPL.NR2F6.Hep-G2 219 bp overlap

NRIP1 2 datasets

ChIP MCF-7 ERP005838.NRIP1.MCF-7 231 bp overlap

ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 215 bp overlap

Nr2f6 1 dataset

Motif DE_12h DE_12h-Nr2f6_MA0677.2 13 bp overlap

POU1F1 1 dataset

Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap

POU2F1 1 dataset

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 2 datasets

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 1 dataset

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU5F1 7 datasets

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 384 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 339 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 482 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 443 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 343 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 258 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

PPARD 1 dataset

Motif DE_12h DE_12h-PPARD_MA1550.2 14 bp overlap

PRDM9 1 dataset

Motif DE_12h DE_12h-PRDM9_MA1723.2 20 bp overlap

Pou5f1::Sox2 2 datasets

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap

RAD21 2 datasets

ChIP MCF-7 ENCFF694KOM 291 bp overlap

ChIP MCF-7 GSE72082.RAD21.MCF-7 121 bp overlap

RARA 3 datasets

ChIP HepG2 ENCFF582XUA 317 bp overlap

ChIP hiPSC_D2 GSE132532.RARA.hiPSC_D2 261 bp overlap

ChIP hiPSC_D5 GSE132532.RARA.hiPSC_D5 475 bp overlap

RARA::RXRA 1 dataset

Motif DE_12h DE_12h-RARARXRA_MA0159.1 17 bp overlap

RARA::RXRG 1 dataset

Motif DE_12h DE_12h-RARARXRG_MA1149.2 17 bp overlap

RELA 1 dataset

ChIP FaDu_LPS GSE132018.RELA.FaDu_LPS 129 bp overlap

RORB 1 dataset

Motif DE_12h DE_12h-RORB_MA1150.2 10 bp overlap

RUNX2 1 dataset

ChIP LNCaP-C4-2B GSE33889.RUNX2.LNCaP-C4-2B 76 bp overlap

RUNX3 1 dataset

Motif DE_12h DE_12h-RUNX3_MA0684.3 8 bp overlap

RXR 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.RXR.pancreatic-progenitor_PP1 207 bp overlap

RXRA 1 dataset

ChIP WA01 ENCSR000BJW.RXRA.WA01 154 bp overlap

RXRB 1 dataset

Motif DE_12h DE_12h-RXRB_MA0855.1 14 bp overlap

RXRG 1 dataset

Motif DE_12h DE_12h-RXRG_MA0856.1 14 bp overlap

Rxra 1 dataset

Motif DE_12h DE_12h-Rxra_MA0512.2 14 bp overlap

SIX2 1 dataset

Motif DE_12h DE_12h-SIX2_MA1119.2 11 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 338 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 270 bp overlap

SMAD2_3 1 dataset

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 314 bp overlap

SMAD3 1 dataset

ChIP HCC1954 GSE104760.SMAD3.HCC1954 146 bp overlap

SMAD4 1 dataset

ChIP Caco-2 GSE112946.SMAD4.Caco-2 156 bp overlap

SMARCA4 2 datasets

ChIP MCF-7 GSE140185.SMARCA4.MCF-7 347 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 369 bp overlap

SMARCB1 5 datasets

ChIP MCF-7 GSE123284.SMARCB1.MCF-7 191 bp overlap

ChIP MCF-7_4-hydroxytamoxifen GSE123284.SMARCB1.MCF-7_4-hydroxytamoxifen 311 bp overlap

ChIP MCF-7_Fulvestrant GSE123284.SMARCB1.MCF-7_Fulvestrant 180 bp overlap

ChIP MCF-7_estrogen GSE123284.SMARCB1.MCF-7_estrogen 245 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 288 bp overlap

SMARCC1 2 datasets

ChIP DE_D1 S15-DE-d1-BAF155-exp1 292 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 200 bp overlap

SMARCD3 1 dataset

ChIP MCF-7 GSE124225.SMARCD3.MCF-7 113 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 311 bp overlap

SP4 1 dataset

Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap

SP5 1 dataset

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

SPIB 1 dataset

Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap

STAT3 7 datasets

ChIP MCF-7_jc5834 GSE126004.STAT3.MCF-7_jc5834 91 bp overlap

ChIP MCF-7_jc5836 GSE126004.STAT3.MCF-7_jc5836 242 bp overlap

ChIP MCF-7_jc5838 GSE126004.STAT3.MCF-7_jc5838 142 bp overlap

ChIP MCF-7_jc5840 GSE126004.STAT3.MCF-7_jc5840 183 bp overlap

ChIP MCF-7_jc5844 GSE126004.STAT3.MCF-7_jc5844 97 bp overlap

ChIP MCF-7_jc5846 GSE126004.STAT3.MCF-7_jc5846 70 bp overlap

ChIP MCF-7_jc5848 GSE126004.STAT3.MCF-7_jc5848 197 bp overlap

Spi1 1 dataset

Motif DE_12h DE_12h-Spi1_MA0080.7 13 bp overlap

TEAD4 1 dataset

ChIP H1 ENCFF778PAX 245 bp overlap

THRB 1 dataset

Motif DE_12h DE_12h-THRB_MA1574.2 13 bp overlap

TRIM28 2 datasets

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 206 bp overlap

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 62 bp overlap

TRPS1 1 dataset

ChIP MCF-7 GSE133072.TRPS1.MCF-7 311 bp overlap

ZNF143 1 dataset

ChIP MCF-7 GSE76454.ZNF143.MCF-7 157 bp overlap

ZNF148 1 dataset

Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap

ZNF157 1 dataset

Motif DE_12h DE_12h-ZNF157_MA2331.1 21 bp overlap

ZNF217 1 dataset

ChIP MCF-7 ENCSR465XQW.ZNF217.MCF-7 372 bp overlap

ZNF24 1 dataset

Motif DE_12h DE_12h-ZNF24_MA1124.1 13 bp overlap

ZNF257 1 dataset

Motif DE_12h DE_12h-ZNF257_MA1710.2 10 bp overlap

ZNF384 1 dataset

Motif DE_12h DE_12h-ZNF384_MA1125.2 8 bp overlap

ZNF682 1 dataset

Motif DE_12h DE_12h-ZNF682_MA1599.2 11 bp overlap

ZNF766 1 dataset

Motif DE_12h DE_12h-ZNF766_MA2098.1 9 bp overlap