chr21 : 44,263,347 – 44,263,697
350 bp 99 TFs 1 linked gene
This 350 bp open chromatin element is linked to DNMT3L and is bound by 99 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
DNMT3L 1.1 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr21:44,258,347 – 44,268,697
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
99 transcription factors
Source
Cell type
AGO1 3 datasets
ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 209 bp overlap
ChIP Hep-G2 GSE120104.AGO1.Hep-G2 209 bp overlap
ChIP K-562 ENCSR641BSL.AGO1.K-562 183 bp overlap
AR 1 dataset
ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 201 bp overlap
BCL11A 1 dataset
ChIP HEK293 ENCSR021DJC.BCL11A.HEK293 229 bp overlap
BRD2 1 dataset
ChIP K-562_DMSO GSE138084.BRD2.K-562_DMSO 246 bp overlap
BRD3 1 dataset
ChIP K-562_DMSO GSE138084.BRD3.K-562_DMSO 280 bp overlap
BRD4 10 datasets
ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 318 bp overlap
ChIP CLL_patient3 GSE109411.BRD4.CLL_patient3 180 bp overlap
ChIP COLO-741 GSE73319.BRD4.COLO-741 300 bp overlap
ChIP HAP1 GSE108387.BRD4.HAP1 350 bp overlap
ChIP K-562_DMSO GSE138084.BRD4.K-562_DMSO 350 bp overlap
ChIP K-562_DMSO-IFNG GSE138084.BRD4.K-562_DMSO-IFNG 292 bp overlap
ChIP MCF-10A ERP003925.BRD4.MCF-10A 174 bp overlap
ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 350 bp overlap
ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 350 bp overlap
ChIP retina_AB1-FW23 GSE86981.BRD4.retina_AB1-FW23 350 bp overlap
CBFA2T2 1 dataset
ChIP NCCIT GSE71675.CBFA2T2.NCCIT 350 bp overlap
CBFB 1 dataset
ChIP ME-1 GSE46044.CBFB.ME-1 206 bp overlap
CTCF 1 dataset
ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 237 bp overlap
DNMT3B 1 dataset
ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 76 bp overlap
EGR1 2 datasets
ChIP A-375 GSE116190.EGR1.A-375 268 bp overlap
ChIP Hep-G2 ENCSR026GSW.EGR1.Hep-G2 237 bp overlap
ELF1 1 dataset
ChIP GM12878 ENCSR000BMB.ELF1.GM12878 93 bp overlap
ERG 2 datasets
ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 185 bp overlap
ChIP ME-1 GSE46044.ERG.ME-1 256 bp overlap
ESR1 13 datasets
ChIP Ishikawa_C2-3 GSE147141.ESR1.Ishikawa_C2-3 350 bp overlap
ChIP Ishikawa_E2 GSE132426.ESR1.Ishikawa_E2 291 bp overlap
ChIP Ishikawa_E2-1h GSE129803.ESR1.Ishikawa_E2-1h 246 bp overlap
ChIP Ishikawa_ETV4-KO1_Mili GSE129803.ESR1.Ishikawa_ETV4-KO1_Mili 310 bp overlap
ChIP Ishikawa_ETV4-KO2_Mili GSE129803.ESR1.Ishikawa_ETV4-KO2_Mili 312 bp overlap
ChIP Ishikawa_M2-3 GSE147141.ESR1.Ishikawa_M2-3 213 bp overlap
ChIP Ishikawa_siETV4-72h GSE129803.ESR1.Ishikawa_siETV4-72h 339 bp overlap
ChIP Ishikawa_siNTC-72h GSE129803.ESR1.Ishikawa_siNTC-72h 347 bp overlap
ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 350 bp overlap
ChIP MCF-7_DHT GSE99626.ESR1.MCF-7_DHT 155 bp overlap
ChIP MCF-7_estradiol-DHT_45min GSE99626.ESR1.MCF-7_estradiol-DHT_45min 163 bp overlap
ChIP MDA-MB-231_LQ_45min GSE95121.ESR1.MDA-MB-231_LQ_45min 196 bp overlap
ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 349 bp overlap
ETS1 1 dataset
ChIP cardiomyocyte_D0 GSE129986.ETS1.cardiomyocyte_D0 293 bp overlap
FOXP1 1 dataset
ChIP H9 GSE31006.FOXP1.H9 179 bp overlap
GABPA 1 dataset
ChIP WA01 ENCSR000BIW.GABPA.WA01 198 bp overlap
GATA6 1 dataset
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 338 bp overlap
GLIS1 2 datasets
ChIP HEK293 ENCFF299RSE 149 bp overlap
ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 350 bp overlap
GLIS2 3 datasets
ChIP HCT-116_5FU GSE125927.GLIS2.HCT-116_5FU 174 bp overlap
ChIP HCT-116_DMSO GSE125927.GLIS2.HCT-116_DMSO 115 bp overlap
ChIP HEK293 ENCSR535DIA.GLIS2.HEK293 313 bp overlap
GLIS3 1 dataset
ChIP H9_plus GSE109562.GLIS3.H9_plus 350 bp overlap
GTF2F1 1 dataset
ChIP K-562 ENCSR377BLZ.GTF2F1.K-562 194 bp overlap
HEXIM1 1 dataset
ChIP HCT-116 GSE72622.HEXIM1.HCT-116 287 bp overlap
HNRNPK 4 datasets
ChIP Hep-G2 GSE120104.HNRNPK.Hep-G2 130 bp overlap
ChIP Hep-G2 ENCSR519QAA.HNRNPK.Hep-G2 90 bp overlap
ChIP HepG2 ENCFF493GNS 203 bp overlap
ChIP HepG2 ENCFF826MXP 200 bp overlap
IKZF1 2 datasets
ChIP K-562 ENCSR395HWC.IKZF1.K-562 127 bp overlap
ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 151 bp overlap
IKZF3 1 dataset
ChIP pre-B-cell GSE107886.IKZF3.pre-B-cell 263 bp overlap
JUN 2 datasets
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 236 bp overlap
ChIP MDA-BoM-1833_shp27 GSE112444.JUN.MDA-BoM-1833_shp27 223 bp overlap
KLF1 1 dataset
ChIP HEK293 ENCFF159QSW 350 bp overlap
KLF17 1 dataset
ChIP HEK293 ENCSR065WUF.KLF17.HEK293 350 bp overlap
KLF4 3 datasets
ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 93 bp overlap
ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 207 bp overlap
ChIP HAP1 GSE130417.KLF4.HAP1 231 bp overlap
KLF8 1 dataset
ChIP HEK293 ENCSR635NOQ.KLF8.HEK293 119 bp overlap
KMT2A 2 datasets
ChIP Hep-G2 ENCSR692GFR.KMT2A.Hep-G2 149 bp overlap
ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 325 bp overlap
MAF1 1 dataset
ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 217 bp overlap
MAZ 3 datasets
ChIP HEK293 ENCSR290SSQ.MAZ.HEK293 270 bp overlap
ChIP HEK293 GSE76494.MAZ.HEK293 195 bp overlap
ChIP K-562 ENCSR000EFX.MAZ.K-562 110 bp overlap
MED1 2 datasets
ChIP HCT-116_shLuc_thaps GSE121798.MED1.HCT-116_shLuc_thaps 276 bp overlap
ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 57 bp overlap
MITF 1 dataset
ChIP 501-mel_20ng_K243R GSE137522.MITF.501-mel_20ng_K243R 193 bp overlap
MTA2 1 dataset
ChIP pre-B-cell GSE107886.MTA2.pre-B-cell 261 bp overlap
NANOG 1 dataset
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 347 bp overlap
NCAPH2 1 dataset
ChIP HEK293 GSE97540.NCAPH2.HEK293 280 bp overlap
NELFE 1 dataset
ChIP K-562_HS GSE112379.NELFE.K-562_HS 175 bp overlap
NR2F1 3 datasets
ChIP GM12878 ENCSR514VYD.NR2F1.GM12878 223 bp overlap
ChIP K-562 ENCSR970NKQ.NR2F1.K-562 350 bp overlap
ChIP K562 ENCFF221HJH 349 bp overlap
OGG1 3 datasets
ChIP HEK293 GSE89017.OGG1.HEK293 330 bp overlap
ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 341 bp overlap
ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 244 bp overlap
PATZ1 4 datasets
ChIP HEK293 ENCFF016MNJ 343 bp overlap
ChIP HEK293 ENCSR966ULI.PATZ1.HEK293 350 bp overlap
ChIP HepG2 ENCFF723PFC 350 bp overlap
ChIP HepG2 ENCFF723PFC 193 bp overlap
PCBP1 3 datasets
ChIP Hep-G2 GSE120104.PCBP1.Hep-G2 168 bp overlap
ChIP K-562 GSE120104.PCBP1.K-562 153 bp overlap
ChIP K-562 ENCSR052PTN.PCBP1.K-562 154 bp overlap
PLAG1 1 dataset
ChIP K-562 GSE111469.PLAG1.K-562 350 bp overlap
POU5F1 5 datasets
ChIP BG03 GSE21614.POU5F1.BG03 257 bp overlap
ChIP DE_D1 DED1-OCT4_Batch_II 350 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 219 bp overlap
ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 301 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 262 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 348 bp overlap
PRDM10 3 datasets
ChIP HEK293 ENCFF145WQQ 84 bp overlap
ChIP HEK293 ENCFF145WQQ 183 bp overlap
ChIP K562 ENCFF740YLK 72 bp overlap
PRDM14 1 dataset
ChIP NCCIT GSE71675.PRDM14.NCCIT 350 bp overlap
RBM39 2 datasets
ChIP Hep-G2 ENCSR339JTP.RBM39.Hep-G2 253 bp overlap
ChIP Hep-G2 GSE120104.RBM39.Hep-G2 230 bp overlap
RUNX1 1 dataset
ChIP 697 GSE138031.RUNX1.697 79 bp overlap
SIRT6 1 dataset
ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 278 bp overlap
SMAD2 1 dataset
ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 266 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 350 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 350 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 350 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 350 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 341 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 302 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 350 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 350 bp overlap
SMAD3 1 dataset
ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 153 bp overlap
SMAD4 1 dataset
ChIP hESC GSE29422.SMAD4.hESC 137 bp overlap
SMARCA4 3 datasets
ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 350 bp overlap
ChIP NSC GSE125033.SMARCA4.NSC 350 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 234 bp overlap
SMARCB1 2 datasets
ChIP HeLa-S3 ENCSR000EDK.SMARCB1.HeLa-S3 237 bp overlap
ChIP hiPSC GSE124903.SMARCB1.hiPSC 289 bp overlap
SMARCC1 1 dataset
ChIP hiPSC GSE124903.SMARCC1.hiPSC 271 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 315 bp overlap
SOX2 3 datasets
ChIP HNSC GSE69479.SOX2.HNSC 182 bp overlap
ChIP RENVM GSE49404.SOX2.RENVM 212 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 158 bp overlap
SP1 1 dataset
ChIP HEK293 GSE76494.SP1.HEK293 183 bp overlap
SP2 2 datasets
ChIP HEK293 GSE76494.SP2.HEK293 246 bp overlap
ChIP HEK293 ENCSR807LQP.SP2.HEK293 195 bp overlap
SP4 1 dataset
ChIP HEK293 GSE76494.SP4.HEK293 262 bp overlap
SREBP2 1 dataset
ChIP HCC70 GSE126380.SREBP2.HCC70 350 bp overlap
SS18 1 dataset
ChIP SYO-1 GSE108025.SS18.SYO-1 105 bp overlap
SUZ12 1 dataset
ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 273 bp overlap
T 2 datasets
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 348 bp overlap
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 233 bp overlap
TAF15 1 dataset
ChIP Hep-G2 GSE120104.TAF15.Hep-G2 255 bp overlap
TCF3 1 dataset
ChIP RCH-ACV GSE85988.TCF3.RCH-ACV 273 bp overlap
TET2 1 dataset
ChIP Jurkat_NCKD GSE85524.TET2.Jurkat_NCKD 163 bp overlap
TFAP2A 1 dataset
ChIP WA09 GSE105081.TFAP2A.WA09 190 bp overlap
TFAP2C 2 datasets
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 350 bp overlap
ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 350 bp overlap
TFIIIC 1 dataset
ChIP HEK293 GSE119418.TFIIIC.HEK293 257 bp overlap
TP63 1 dataset
ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 213 bp overlap
USF1 3 datasets
ChIP H1 ENCFF090WVU 193 bp overlap
ChIP Hep-G2 ENCSR000BGM.USF1.Hep-G2 93 bp overlap
ChIP WA01 ENCSR000BIU.USF1.WA01 192 bp overlap
USF2 2 datasets
ChIP K-562 GSE111469.USF2.K-562 289 bp overlap
ChIP WTC11 ENCFF139JAW 303 bp overlap
ZBED4 1 dataset
ChIP Hep-G2 ENCSR409PMR.ZBED4.Hep-G2 225 bp overlap
ZBTB10 1 dataset
ChIP HEK293 ENCSR004PLU.ZBTB10.HEK293 234 bp overlap
ZBTB20 2 datasets
ChIP HEK293 ENCFF524ADK 350 bp overlap
ChIP HEK293 ENCSR460MBI.ZBTB20.HEK293 219 bp overlap
ZBTB33 1 dataset
ChIP K562 ENCFF427SDV 350 bp overlap
ZBTB7A 7 datasets
ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 276 bp overlap
ChIP Hep-G2 ENCSR000BQA.ZBTB7A.Hep-G2 263 bp overlap
ChIP Ishikawa ENCFF191NFH 350 bp overlap
ChIP Ishikawa ENCSR000BSZ.ZBTB7A.Ishikawa 350 bp overlap
ChIP K-562 ENCSR000BME.ZBTB7A.K-562 350 bp overlap
ChIP K-562 GSE103445.ZBTB7A.K-562 350 bp overlap
ChIP K562 ENCFF579ZGM 216 bp overlap
ZBTB7B 1 dataset
ChIP Hep-G2 ENCSR322ULL.ZBTB7B.Hep-G2 134 bp overlap
ZFHX2 1 dataset
ChIP HEK293 ENCFF167TUA 350 bp overlap
ZFP64 1 dataset
ChIP HEK293 GSE76494.ZFP64.HEK293 108 bp overlap
ZFX 1 dataset
ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 350 bp overlap
ZIC2 1 dataset
ChIP HEK293 ENCFF033NQQ 208 bp overlap
ZNF263 1 dataset
ChIP K-562 ENCSR000EWN.ZNF263.K-562 283 bp overlap
ZNF274 1 dataset
ChIP Hep-G2 ENCSR871VNN.ZNF274.Hep-G2 158 bp overlap
ZNF341 2 datasets
ChIP HEK293 GSE76494.ZNF341.HEK293 171 bp overlap
ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 180 bp overlap
ZNF534 1 dataset
ChIP HEK293T GSE78099.ZNF534.HEK293T 87 bp overlap
ZNF572 1 dataset
ChIP Hep-G2 ENCSR663CTC.ZNF572.Hep-G2 270 bp overlap
ZNF598 1 dataset
ChIP Hep-G2 ENCSR173NAL.ZNF598.Hep-G2 224 bp overlap
ZNF687 1 dataset
ChIP HepG2 ENCFF653WIX 350 bp overlap
ZNF711 1 dataset
ChIP HEK293T GSE145160.ZNF711.HEK293T 350 bp overlap
ZNF883 1 dataset
ChIP Hep-G2 ENCSR882YYL.ZNF883.Hep-G2 210 bp overlap
ZNF891 1 dataset
ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 217 bp overlap
ZNF90 1 dataset
ChIP HEK293T GSE78099.ZNF90.HEK293T 65 bp overlap
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