chr16:72,111,833–72,112,319

chr16 : 72,111,833 – 72,112,319

486 bp 60 TFs 8 linked genes

This 486 bp open chromatin element is linked to 8 target genes and is bound by 60 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
DHX38		18.3 kb	Distal	Multiome
TXNL4B		18.5 kb	Distal	Multiome
PMFBP1		60.0 kb	Distal	Multiome
DHODH		103.4 kb	Distal	Multiome
PKD1L3		111.8 kb	Distal	Multiome
IST1		216.6 kb	Distal	Multiome
ZNF821		228.0 kb	Distal	Multiome
ATXN1L		266.2 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

60 transcription factors

AGO2 2 datasets

ChIP HepG2 ENCFF252VFI 123 bp overlap

ChIP HepG2 ENCFF773YDL 123 bp overlap

ARID1B 1 dataset

ChIP K-562 ENCSR822CCM.ARID1B.K-562 103 bp overlap

ChIP K-562 ENCSR028UIU.ATF3.K-562 141 bp overlap

ChIP K-562 ENCSR972ZBV.ATF7.K-562 284 bp overlap

BHLHE40 2 datasets

ChIP K-562 ENCSR000EGV.BHLHE40.K-562 389 bp overlap

ChIP K562 ENCFF923NJI 195 bp overlap

BRD4 2 datasets

ChIP HEK293_Ctrl GSE129407.BRD4.HEK293_Ctrl 190 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD4.K-562_iBET-BD2-IFNG 167 bp overlap

ChIP Caco-2_DIFF GSE23436.CDX2.Caco-2_DIFF 191 bp overlap

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 264 bp overlap

DNMT3B 1 dataset

ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 167 bp overlap

E2F6 3 datasets

ChIP K-562 ENCSR000EWJ.E2F6.K-562 168 bp overlap

ChIP K-562 ENCSR000BLI.E2F6.K-562 114 bp overlap

ChIP K562 ENCFF136LTS 239 bp overlap

ESR1 3 datasets

ChIP MCF-7_PaPE-1 GSE93510.ESR1.MCF-7_PaPE-1 107 bp overlap

ChIP MCF-7_Veh GSE93510.ESR1.MCF-7_Veh 345 bp overlap

ChIP MCF-7_estradiol-DHT_45min GSE99626.ESR1.MCF-7_estradiol-DHT_45min 208 bp overlap

FOSL1 2 datasets

ChIP K-562 ENCSR239ZLZ.FOSL1.K-562 318 bp overlap

ChIP K562 ENCFF455MKD 413 bp overlap

FOXJ2 1 dataset

ChIP K562 ENCFF457GZC 402 bp overlap

GATA1 1 dataset

ChIP K-562 GSE107726.GATA1.K-562 159 bp overlap

GATA4 1 dataset

ChIP DE DE-GATA4-2 434 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 436 bp overlap

ChIP DE DE-GATA6-2 414 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 486 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 486 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 430 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 484 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 486 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 486 bp overlap

HDAC1 3 datasets

ChIP K-562 ENCSR387UWP.HDAC1.K-562 230 bp overlap

ChIP K-562_dilution-6-100 GSE140325.HDAC1.K-562_dilution-6-100 92 bp overlap

ChIP K562 ENCFF968WBH 315 bp overlap

ChIP K-562 ENCSR563YDA.HDGF.K-562 377 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 408 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 486 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 486 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 486 bp overlap

ChIP K-562 ENCSR000EFS.JUN.K-562 116 bp overlap

ChIP K-562 ENCSR000FAH.JUN.K-562 141 bp overlap

ChIP K-562 ENCSR000DJY.JUNB.K-562 314 bp overlap

JUND 3 datasets

ChIP K-562 ENCSR000EGN.JUND.K-562 157 bp overlap

ChIP K562 ENCFF336RCR 297 bp overlap

ChIP K562 ENCFF336RCR 446 bp overlap

L3MBTL2 2 datasets

ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 359 bp overlap

ChIP K562 ENCFF320EQC 255 bp overlap

ChIP CCRF-CEM GSE33850.LMO2.CCRF-CEM 191 bp overlap

ChIP K-562 ENCSR000EFV.MAX.K-562 187 bp overlap

ChIP K562 ENCFF110LJS 215 bp overlap

ChIP K562 ENCFF398VJM 322 bp overlap

ChIP K562 ENCFF524IJO 156 bp overlap

ChIP K-562 ENCSR000EFX.MAZ.K-562 118 bp overlap

ChIP K562 ENCFF333ZIV 243 bp overlap

ChIP K-562 ENCSR710WLO.MGA.K-562 183 bp overlap

ChIP K562 ENCFF140CEX 367 bp overlap

MITF 3 datasets

ChIP K-562 ENCSR797SWM.MITF.K-562 182 bp overlap

ChIP K-562 ENCSR000FCB.MITF.K-562 83 bp overlap

ChIP K562 ENCFF731XJJ 132 bp overlap

ChIP K-562 ENCSR390VGH.MNT.K-562 207 bp overlap

ChIP K-562 ENCSR512NLO.MNT.K-562 334 bp overlap

ChIP K-562 ENCSR979QYJ.MNT.K-562 164 bp overlap

ChIP K562 ENCFF450LDL 310 bp overlap

ChIP K562 ENCFF820IGH 399 bp overlap

MRTFB 1 dataset

ChIP A-673-clone-Asp114 GSE92738.MRTFB.A-673-clone-Asp114 284 bp overlap

ChIP K-562 ENCSR180NCY.MTA3.K-562 115 bp overlap

ChIP G-401_EGFP GSE109310.MYC.G-401_EGFP 265 bp overlap

ChIP K-562 ENCSR000EZV.MYC.K-562 157 bp overlap

ChIP K-562 ENCSR000EZU.MYC.K-562 158 bp overlap

ChIP K-562 ENCSR000EGJ.MYC.K-562 159 bp overlap

ChIP K-562 ENCSR000EGS.MYC.K-562 157 bp overlap

ChIP K-562 ENCSR000FAG.MYC.K-562 118 bp overlap

ChIP K562 ENCFF263IVY 203 bp overlap

ChIP K562 ENCFF988ZRU 261 bp overlap

NFE2 2 datasets

ChIP K-562 ENCSR000FCC.NFE2.K-562 64 bp overlap

ChIP K562 ENCFF047YKA 168 bp overlap

NFE2L2 1 dataset

ChIP K-562 ENCSR485GKE.NFE2L2.K-562 154 bp overlap

NR2C1 1 dataset

ChIP K562 ENCFF568JLK 272 bp overlap

NR2F1 2 datasets

ChIP K-562 ENCSR970NKQ.NR2F1.K-562 286 bp overlap

ChIP K562 ENCFF221HJH 396 bp overlap

NR2F2 1 dataset

ChIP K-562 ENCSR000BRS.NR2F2.K-562 160 bp overlap

PLAG1 1 dataset

ChIP K-562 GSE111469.PLAG1.K-562 486 bp overlap

POLR2A 5 datasets

ChIP GM12878 ENCFF412KAE 365 bp overlap

ChIP GM12878 ENCFF412KAE 130 bp overlap

ChIP GM12891 ENCFF012SUT 462 bp overlap

ChIP GM12891 ENCFF012SUT 390 bp overlap

ChIP HepG2 ENCFF422YUC 221 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 478 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 486 bp overlap

RAD51 2 datasets

ChIP K-562 ENCSR524BUE.RAD51.K-562 164 bp overlap

ChIP K562 ENCFF133ELP 261 bp overlap

RBFOX2 2 datasets

ChIP K562 ENCFF196WTG 228 bp overlap

ChIP K562 ENCFF967GRF 228 bp overlap

RBM39 1 dataset

ChIP HepG2 ENCFF084YZE 99 bp overlap

ChIP FaDu_LPS GSE132018.RELA.FaDu_LPS 223 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 444 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 472 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 486 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 401 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 315 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 486 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 58 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 484 bp overlap

SMARCA4 1 dataset

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 421 bp overlap

ChIP K-562 ENCSR788RSW.SOX6.K-562 149 bp overlap

SUPT6H 1 dataset

ChIP HCT-116_Inhibitor GSE130509.SUPT6H.HCT-116_Inhibitor 226 bp overlap

USF1 3 datasets

ChIP K-562 ENCSR000BKT.USF1.K-562 148 bp overlap

ChIP K562 ENCFF202SFC 275 bp overlap

ChIP K562 ENCFF633EZB 153 bp overlap

USF2 3 datasets

ChIP K-562 ENCSR578KEN.USF2.K-562 110 bp overlap

ChIP K562 ENCFF306QPU 359 bp overlap

ChIP K562 ENCFF397QGU 196 bp overlap

VEZF1 2 datasets

ChIP K-562 ENCSR189YMA.VEZF1.K-562 223 bp overlap

ChIP K562 ENCFF053XDV 140 bp overlap

ChIP Huh-7 GSE97411.YY1.Huh-7 153 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 79 bp overlap

ChIP K-562 ENCSR004GKA.ZEB2.K-562 122 bp overlap

ZFP36 1 dataset

ChIP K-562 ENCSR776CYN.ZFP36.K-562 105 bp overlap

ZNF24 2 datasets

ChIP K-562 ENCSR695EQB.ZNF24.K-562 125 bp overlap

ChIP K562 ENCFF497GLV 265 bp overlap

ZNF257 1 dataset

ChIP K-562 ENCSR492FKD.ZNF257.K-562 179 bp overlap

ZNF281 2 datasets

ChIP K562 ENCFF594VNM 290 bp overlap

ChIP K562 ENCFF594VNM 463 bp overlap

ZNF592 1 dataset

ChIP K-562 ENCSR249BHQ.ZNF592.K-562 235 bp overlap