chr8 : 137,783,423 – 137,784,157
734 bp 107 TFs 1 linked gene
This 734 bp open chromatin element is linked to ENSG00000253288 and is bound by 107 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000253288 299.9 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr8:137,778,423 – 137,789,157
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
107 transcription factors
Source
Cell type
ARNT::HIF1A 2 datasets
Motif DE_48h DE_48h-ARNTHIF1A_MA0259.2 5 bp overlap
Motif DE_60h DE_60h-ARNTHIF1A_MA0259.2 5 bp overlap
ASCL1 2 datasets
Motif DE_48h DE_48h-ASCL1_MA1631.2 9 bp overlap
Motif DE_60h DE_60h-ASCL1_MA1631.2 9 bp overlap
BHLHE22 1 dataset
ChIP CAL-1 GSE43876.BHLHE22.CAL-1 161 bp overlap
BRD4 3 datasets
ChIP MM1-S_JQ1_500NM GSE42355.BRD4.MM1-S_JQ1_500NM 215 bp overlap
ChIP MM1-S_JQ1_50NM GSE42355.BRD4.MM1-S_JQ1_50NM 190 bp overlap
ChIP MM1-S_JQ1_5NM GSE42355.BRD4.MM1-S_JQ1_5NM 179 bp overlap
Bcl11B 3 datasets
Motif DE_48h DE_48h-Bcl11B_MA1989.2 9 bp overlap
Motif DE_60h DE_60h-Bcl11B_MA1989.2 9 bp overlap
Motif DE_72h DE_72h-Bcl11B_MA1989.2 9 bp overlap
CDK9 2 datasets
ChIP MOLT-4_DMSO GSE79288.CDK9.MOLT-4_DMSO 424 bp overlap
ChIP MOLT-4_JQ1 GSE79288.CDK9.MOLT-4_JQ1 417 bp overlap
Creb3l2 2 datasets
Motif DE_48h DE_48h-Creb3l2_MA0608.1 9 bp overlap
Motif DE_60h DE_60h-Creb3l2_MA0608.1 9 bp overlap
EED 1 dataset
ChIP GM12878 ENCFF266FYW 482 bp overlap
EOMES 2 datasets
ChIP hESC GSE26097.EOMES.hESC 412 bp overlap
ChIP hESC GSE26097.EOMES.hESC 258 bp overlap
ESR1 1 dataset
ChIP MCF-7_4OH-Tam GSE117941.ESR1.MCF-7_4OH-Tam 104 bp overlap
FIGLA 3 datasets
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 734 bp overlap
ChIP DE DE-FOXA2-2 734 bp overlap
GATA4 7 datasets
ChIP DE DE-GATA4-1 734 bp overlap
ChIP DE DE-GATA4-2 734 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 260 bp overlap
GATA5 1 dataset
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 10 datasets
ChIP DE DE-GATA6-1 734 bp overlap
ChIP DE DE-GATA6-2 734 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 409 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 734 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 734 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 734 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 615 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 734 bp overlap
ChIP foregut GSE117136.GATA6.foregut 361 bp overlap
Gata3 1 dataset
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Gfi1B 1 dataset
Motif DE_60h DE_60h-Gfi1B_MA0483.2 10 bp overlap
HIF1A 1 dataset
ChIP U2OS_trough_DMOG GSE85096.HIF1A.U2OS_trough_DMOG 235 bp overlap
HOXB4 3 datasets
Motif DE_48h DE_48h-HOXB4_MA1499.2 6 bp overlap
Motif DE_60h DE_60h-HOXB4_MA1499.2 6 bp overlap
Motif DE_72h DE_72h-HOXB4_MA1499.2 6 bp overlap
HOXC4 3 datasets
Motif DE_48h DE_48h-HOXC4_MA1504.2 6 bp overlap
Motif DE_60h DE_60h-HOXC4_MA1504.2 6 bp overlap
Motif DE_72h DE_72h-HOXC4_MA1504.2 6 bp overlap
HOXD4 3 datasets
Motif DE_48h DE_48h-HOXD4_MA1507.2 6 bp overlap
Motif DE_60h DE_60h-HOXD4_MA1507.2 6 bp overlap
Motif DE_72h DE_72h-HOXD4_MA1507.2 6 bp overlap
Hnf1A 1 dataset
Motif DE_72h DE_72h-Hnf1A_MA1991.2 10 bp overlap
IKZF1 2 datasets
ChIP GM12878 ENCFF753XDO 532 bp overlap
ChIP GM12878 ENCFF824TGK 521 bp overlap
IKZF2 1 dataset
ChIP GM12878 ENCSR680UQE.IKZF2.GM12878 238 bp overlap
Irf1 1 dataset
Motif DE_60h DE_60h-Irf1_MA0050.4 11 bp overlap
KLF9 1 dataset
ChIP GBM1A GSE62211.KLF9.GBM1A 120 bp overlap
Lef1 1 dataset
Motif DE_72h DE_72h-Lef1_MA0768.3 8 bp overlap
MED1 1 dataset
ChIP MM1-S_JQ1_500NM GSE42355.MED1.MM1-S_JQ1_500NM 176 bp overlap
MEIS1 5 datasets
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MEIS2 1 dataset
Motif DE_60h DE_60h-MEIS2_MA1640.2 9 bp overlap
MTA2 1 dataset
ChIP GM12878 ENCSR293QAR.MTA2.GM12878 221 bp overlap
MYB 7 datasets
Motif DE_48h DE_48h-MYB_MA0100.4 6 bp overlap
Motif DE_48h DE_48h-MYB_MA0100.4 6 bp overlap
Motif DE_60h DE_60h-MYB_MA0100.4 6 bp overlap
Motif DE_60h DE_60h-MYB_MA0100.4 6 bp overlap
Motif DE_72h DE_72h-MYB_MA0100.4 6 bp overlap
ChIP Jurkat GSE59657.MYB.Jurkat 172 bp overlap
ChIP MOLT-3 GSE59657.MYB.MOLT-3 259 bp overlap
MYC 1 dataset
ChIP MM1-S_DMSO GSE36354.MYC.MM1-S_DMSO 368 bp overlap
Msgn1 2 datasets
Motif DE_48h DE_48h-Msgn1_MA1524.3 10 bp overlap
Motif DE_60h DE_60h-Msgn1_MA1524.3 10 bp overlap
NFATC3 3 datasets
Motif DE_48h DE_48h-NFATC3_MA0625.3 6 bp overlap
Motif DE_60h DE_60h-NFATC3_MA0625.3 6 bp overlap
Motif DE_72h DE_72h-NFATC3_MA0625.3 6 bp overlap
NFATC4 3 datasets
Motif DE_48h DE_48h-NFATC4_MA1525.3 9 bp overlap
Motif DE_60h DE_60h-NFATC4_MA1525.3 9 bp overlap
Motif DE_72h DE_72h-NFATC4_MA1525.3 9 bp overlap
NFIA 2 datasets
Motif DE_48h DE_48h-NFIA_MA0670.2 6 bp overlap
Motif DE_60h DE_60h-NFIA_MA0670.2 6 bp overlap
NFIC 1 dataset
ChIP GM12878 ENCSR000BRN.NFIC.GM12878 237 bp overlap
NFIX 2 datasets
Motif DE_48h DE_48h-NFIX_MA0671.2 6 bp overlap
Motif DE_60h DE_60h-NFIX_MA0671.2 6 bp overlap
NKX6-3 3 datasets
Motif DE_48h DE_48h-NKX6-3_MA1530.2 8 bp overlap
Motif DE_60h DE_60h-NKX6-3_MA1530.2 8 bp overlap
Motif DE_72h DE_72h-NKX6-3_MA1530.2 8 bp overlap
NOTCH1 1 dataset
ChIP HPBALL GSE39263.NOTCH1.HPBALL 313 bp overlap
NR2C2 1 dataset
Motif DE_72h DE_72h-NR2C2_MA0504.2 14 bp overlap
NR2F1 1 dataset
Motif DE_72h DE_72h-NR2F1_MA1537.2 13 bp overlap
NR4A1 2 datasets
Motif DE_48h DE_48h-NR4A1_MA1112.3 8 bp overlap
Motif DE_60h DE_60h-NR4A1_MA1112.3 8 bp overlap
NR4A2 2 datasets
Motif DE_48h DE_48h-NR4A2_MA0160.3 8 bp overlap
Motif DE_60h DE_60h-NR4A2_MA0160.3 8 bp overlap
Nfat5 3 datasets
Motif DE_48h DE_48h-Nfat5_MA0606.3 8 bp overlap
Motif DE_60h DE_60h-Nfat5_MA0606.3 8 bp overlap
Motif DE_72h DE_72h-Nfat5_MA0606.3 8 bp overlap
Nfatc1 3 datasets
Motif DE_48h DE_48h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_60h DE_60h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_72h DE_72h-Nfatc1_MA0624.3 6 bp overlap
OSR2 3 datasets
Motif DE_48h DE_48h-OSR2_MA1646.2 8 bp overlap
Motif DE_60h DE_60h-OSR2_MA1646.2 8 bp overlap
Motif DE_72h DE_72h-OSR2_MA1646.2 8 bp overlap
PBX2 1 dataset
Motif DE_60h DE_60h-PBX2_MA1113.3 9 bp overlap
PKNOX2 2 datasets
Motif DE_48h DE_48h-PKNOX2_MA0783.1 12 bp overlap
Motif DE_60h DE_60h-PKNOX2_MA0783.1 12 bp overlap
PLAG1 2 datasets
Motif DE_48h DE_48h-PLAG1_MA0163.1 14 bp overlap
Motif DE_60h DE_60h-PLAG1_MA0163.1 14 bp overlap
POU6F1 3 datasets
Motif DE_48h DE_48h-POU6F1_MA1549.2 7 bp overlap
Motif DE_60h DE_60h-POU6F1_MA1549.2 7 bp overlap
Motif DE_72h DE_72h-POU6F1_MA1549.2 7 bp overlap
POU6F2 3 datasets
Motif DE_48h DE_48h-POU6F2_MA0793.2 9 bp overlap
Motif DE_60h DE_60h-POU6F2_MA0793.2 9 bp overlap
Motif DE_72h DE_72h-POU6F2_MA0793.2 9 bp overlap
PROX1 1 dataset
ChIP SW480 GSE60390.PROX1.SW480 283 bp overlap
Pparg::Rxra 1 dataset
Motif DE_72h DE_72h-PpargRxra_MA0065.3 13 bp overlap
RBPJ 1 dataset
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
REL 3 datasets
Motif DE_48h DE_48h-REL_MA0101.1 10 bp overlap
Motif DE_60h DE_60h-REL_MA0101.1 10 bp overlap
Motif DE_72h DE_72h-REL_MA0101.1 10 bp overlap
RELA 1 dataset
ChIP SW480_16h_TNFa GSE102796.RELA.SW480_16h_TNFa 201 bp overlap
RFX4 2 datasets
Motif DE_48h DE_48h-RFX4_MA0799.3 13 bp overlap
Motif DE_60h DE_60h-RFX4_MA0799.3 13 bp overlap
RUNX1 1 dataset
ChIP THP-1 GSE79899.RUNX1.THP-1 185 bp overlap
RUNX2 3 datasets
Motif DE_48h DE_48h-RUNX2_MA0511.2 9 bp overlap
Motif DE_60h DE_60h-RUNX2_MA0511.2 9 bp overlap
Motif DE_72h DE_72h-RUNX2_MA0511.2 9 bp overlap
RUNX3 4 datasets
Motif DE_48h DE_48h-RUNX3_MA0684.3 8 bp overlap
Motif DE_60h DE_60h-RUNX3_MA0684.3 8 bp overlap
Motif DE_72h DE_72h-RUNX3_MA0684.3 8 bp overlap
ChIP GM12878 ENCFF395WHA 210 bp overlap
Runx1 3 datasets
Motif DE_48h DE_48h-Runx1_MA0002.3 9 bp overlap
Motif DE_60h DE_60h-Runx1_MA0002.3 9 bp overlap
Motif DE_72h DE_72h-Runx1_MA0002.3 9 bp overlap
SMAD2 2 datasets
ChIP endoderm GSE29422.SMAD2.endoderm 295 bp overlap
ChIP endoderm GSE29422.SMAD2.endoderm 142 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 734 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 580 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 413 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 422 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 447 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 734 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 734 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 220 bp overlap
SMAD4 2 datasets
ChIP endoderm GSE29422.SMAD4.endoderm 298 bp overlap
ChIP endoderm GSE29422.SMAD4.endoderm 187 bp overlap
SNAI1 2 datasets
Motif DE_48h DE_48h-SNAI1_MA1558.2 7 bp overlap
Motif DE_60h DE_60h-SNAI1_MA1558.2 7 bp overlap
SNAI2 1 dataset
Motif DE_60h DE_60h-SNAI2_MA0745.3 8 bp overlap
SOX10 2 datasets
Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 292 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 451 bp overlap
SOX4 2 datasets
Motif DE_48h DE_48h-SOX4_MA0867.3 8 bp overlap
Motif DE_60h DE_60h-SOX4_MA0867.3 8 bp overlap
Stat5a 3 datasets
Motif DE_48h DE_48h-Stat5a_MA1624.2 9 bp overlap
Motif DE_60h DE_60h-Stat5a_MA1624.2 9 bp overlap
Motif DE_72h DE_72h-Stat5a_MA1624.2 9 bp overlap
Stat5b 1 dataset
Motif DE_48h DE_48h-Stat5b_MA1625.2 9 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 232 bp overlap
TAL1 2 datasets
ChIP MOLT-3 GSE59657.TAL1.MOLT-3 421 bp overlap
ChIP RPMI8402 GSE39179.TAL1.RPMI8402 310 bp overlap
TBX21 1 dataset
ChIP GM12878 ENCSR739IHN.TBX21.GM12878 308 bp overlap
TCF12 5 datasets
Motif DE_48h DE_48h-TCF12_MA1648.2 7 bp overlap
Motif DE_60h DE_60h-TCF12_MA1648.2 7 bp overlap
ChIP GM12878 ENCFF433DMU 341 bp overlap
ChIP GM12878 ENCSR725VFL.TCF12.GM12878 207 bp overlap
ChIP RPMI8402 GSE39179.TCF12.RPMI8402 258 bp overlap
TCF3 3 datasets
Motif DE_48h DE_48h-TCF3_MA0522.4 7 bp overlap
Motif DE_60h DE_60h-TCF3_MA0522.4 7 bp overlap
ChIP RCH-ACV GSE85988.TCF3.RCH-ACV 361 bp overlap
TCF4 4 datasets
ChIP CAL-1 GSE76147.TCF4.CAL-1 310 bp overlap
Motif DE_48h DE_48h-TCF4_MA0830.3 8 bp overlap
Motif DE_60h DE_60h-TCF4_MA0830.3 8 bp overlap
ChIP GEN2-2 GSE76147.TCF4.GEN2-2 300 bp overlap
TCF7 3 datasets
Motif DE_72h DE_72h-TCF7_MA0769.3 7 bp overlap
ChIP GM12878 ENCFF749DPM 365 bp overlap
ChIP GM12878 ENCSR501DKS.TCF7.GM12878 171 bp overlap
TCF7L1 1 dataset
Motif DE_72h DE_72h-TCF7L1_MA1421.1 12 bp overlap
TCF7L2 1 dataset
Motif DE_72h DE_72h-TCF7L2_MA0523.2 9 bp overlap
TGIF1 2 datasets
Motif DE_48h DE_48h-TGIF1_MA0796.1 12 bp overlap
Motif DE_60h DE_60h-TGIF1_MA0796.1 12 bp overlap
TGIF2 2 datasets
Motif DE_48h DE_48h-TGIF2_MA0797.1 12 bp overlap
Motif DE_60h DE_60h-TGIF2_MA0797.1 12 bp overlap
THRB 1 dataset
Motif DE_48h DE_48h-THRB_MA1575.2 17 bp overlap
TP53 2 datasets
Motif DE_48h DE_48h-TP53_MA0106.3 18 bp overlap
Motif DE_60h DE_60h-TP53_MA0106.3 18 bp overlap
TRIM22 1 dataset
ChIP GM12878 ENCSR637QAM.TRIM22.GM12878 243 bp overlap
TRPS1 1 dataset
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
ZBTB24 1 dataset
Motif DE_48h DE_48h-ZBTB24_MA2330.1 10 bp overlap
ZEB1 3 datasets
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
ZIC1 2 datasets
Motif DE_48h DE_48h-ZIC1_MA0696.1 14 bp overlap
Motif DE_60h DE_60h-ZIC1_MA0696.1 14 bp overlap
ZIC4 2 datasets
Motif DE_48h DE_48h-ZIC4_MA0751.2 14 bp overlap
Motif DE_60h DE_60h-ZIC4_MA0751.2 14 bp overlap
ZIC5 2 datasets
Motif DE_48h DE_48h-ZIC5_MA1584.2 15 bp overlap
Motif DE_60h DE_60h-ZIC5_MA1584.2 15 bp overlap
ZNF184 3 datasets
Motif DE_48h DE_48h-ZNF184_MA2120.1 13 bp overlap
Motif DE_60h DE_60h-ZNF184_MA2120.1 13 bp overlap
Motif DE_72h DE_72h-ZNF184_MA2120.1 13 bp overlap
ZNF19 1 dataset
ChIP HEK293T GSE78099.ZNF19.HEK293T 313 bp overlap
ZNF24 2 datasets
Motif DE_60h DE_60h-ZNF24_MA1124.1 13 bp overlap
Motif DE_72h DE_72h-ZNF24_MA1124.1 13 bp overlap
ZNF273 1 dataset
ChIP HEK293T GSE78099.ZNF273.HEK293T 88 bp overlap
ZNF282 1 dataset
Motif DE_48h DE_48h-ZNF282_MA1154.2 15 bp overlap
ZNF324 1 dataset
Motif DE_60h DE_60h-ZNF324_MA1977.2 14 bp overlap
ZNF354C 3 datasets
Motif DE_48h DE_48h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_60h DE_60h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_72h DE_72h-ZNF354C_MA0130.1 6 bp overlap
ZNF440 1 dataset
ChIP HEK293T GSE78099.ZNF440.HEK293T 301 bp overlap
ZNF682 1 dataset
Motif DE_48h DE_48h-ZNF682_MA1599.2 11 bp overlap
ZNF768 2 datasets
Motif DE_48h DE_48h-ZNF768_MA1731.2 9 bp overlap
Motif DE_60h DE_60h-ZNF768_MA1731.2 9 bp overlap
ZSCAN16 2 datasets
Motif DE_48h DE_48h-ZSCAN16_MA2100.1 18 bp overlap
Motif DE_60h DE_60h-ZSCAN16_MA2100.1 18 bp overlap
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