chr8 : 131,318,226 – 131,319,981
1,755 bp 117 TFs 1 linked gene
This 1.8 kb open chromatin element is linked to IADEN and is bound by 117 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
IADEN 9.7 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr8:131,313,226 – 131,324,981
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
117 transcription factors
Source
Cell type
AR 15 datasets
ChIP LNCaP GSE80256.AR.LNCaP 256 bp overlap
ChIP LNCaP_DHTTHZ1 GSE125245.AR.LNCaP_DHTTHZ1 126 bp overlap
ChIP LNCaP_SHFOXP1_DHT GSE62492.AR.LNCaP_SHFOXP1_DHT 203 bp overlap
ChIP LNCaP_Talen_DHT GSE89938.AR.LNCaP_Talen_DHT 233 bp overlap
ChIP LTAD_siControl GSE94577.AR.LTAD_siControl 229 bp overlap
ChIP VCaP_R1881 GSE79128.AR.VCaP_R1881 260 bp overlap
ChIP VCaP_R1881_30M GSE84432.AR.VCaP_R1881_30M 152 bp overlap
ChIP VCaP_R1881_4H GSE84432.AR.VCaP_R1881_4H 224 bp overlap
ChIP VCaP_SH1_DHT GSE79128.AR.VCaP_SH1_DHT 251 bp overlap
ChIP VCaP_SH1_R1881 GSE79128.AR.VCaP_SH1_R1881 306 bp overlap
ChIP VCaP_SH2_DHT GSE79128.AR.VCaP_SH2_DHT 346 bp overlap
ChIP VCaP_SH2_R1881 GSE79128.AR.VCaP_SH2_R1881 302 bp overlap
ChIP VCaP_SH3_DHT GSE79128.AR.VCaP_SH3_DHT 384 bp overlap
ChIP WTC11 ENCFF267GQJ 317 bp overlap
ChIP breast-cancer_ENOB-2852 GSE128018.AR.breast-cancer_ENOB-2852 394 bp overlap
ASCL1 1 dataset
Motif ES_0h ES_0h-ASCL1_MA1631.2 9 bp overlap
BRD2 3 datasets
ChIP HCC1806_NTsiRNA_JQ1 GSE116879.BRD2.HCC1806_NTsiRNA_JQ1 253 bp overlap
ChIP K-562_IBET151_500nM GSE120715.BRD2.K-562_IBET151_500nM 216 bp overlap
ChIP K-562_IBET151_50nM GSE120715.BRD2.K-562_IBET151_50nM 206 bp overlap
BRD4 1 dataset
ChIP MV4-11_IBET151_5000nM GSE120715.BRD4.MV4-11_IBET151_5000nM 162 bp overlap
CREB1 2 datasets
ChIP GM23338 ENCFF432ZEW 305 bp overlap
ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 163 bp overlap
CTCF 1 dataset
ChIP glioblastoma_GBM3565 GSE139416.CTCF.glioblastoma_GBM3565 335 bp overlap
Crx 1 dataset
Motif ES_0h ES_0h-Crx_MA0467.3 6 bp overlap
EOMES 2 datasets
Motif ES_0h ES_0h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 246 bp overlap
ERG 3 datasets
ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 185 bp overlap
ChIP VCaP GSE49091.ERG.VCaP 193 bp overlap
ChIP WTC11 ENCFF011YUL 281 bp overlap
ESR1 1 dataset
ChIP breast_tumor_BADOUTCOME GSE40867.ESR1.breast_tumor_BADOUTCOME 198 bp overlap
ETV2::FOXI1 2 datasets
Motif DE_12h DE_12h-ETV2FOXI1_MA1942.2 11 bp overlap
Motif DE_48h DE_48h-ETV2FOXI1_MA1942.2 11 bp overlap
EWSR1-FLI1 2 datasets
Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_36h DE_36h-EWSR1-FLI1_MA0149.1 18 bp overlap
EZH2 3 datasets
ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 617 bp overlap
ChIP OCI-Ly1 GSE45982.EZH2.OCI-Ly1 112 bp overlap
ChIP Pfeiffer GSE45982.EZH2.Pfeiffer 162 bp overlap
FIGLA 3 datasets
Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap
Motif ES_0h ES_0h-FIGLA_MA0820.2 6 bp overlap
Motif ES_0h ES_0h-FIGLA_MA0820.2 6 bp overlap
FOSL2 1 dataset
Motif DE_36h DE_36h-FOSL2_MA0478.2 10 bp overlap
FOXA1 2 datasets
ChIP LNCaP_SHGATA2_R1881 GSE69043.FOXA1.LNCaP_SHGATA2_R1881 137 bp overlap
ChIP T-47D_JC4743 GSE126004.FOXA1.T-47D_JC4743 197 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 968 bp overlap
ChIP DE DE-FOXA2-2 913 bp overlap
FOXC2 1 dataset
Motif DE_48h DE_48h-FOXC2_MA0846.2 11 bp overlap
FOXD2 1 dataset
Motif DE_48h DE_48h-FOXD2_MA0847.4 11 bp overlap
FOXE1 1 dataset
Motif DE_48h DE_48h-FOXE1_MA1487.3 12 bp overlap
FOXS1 1 dataset
Motif DE_48h DE_48h-FOXS1_MA2118.1 8 bp overlap
Foxl2 1 dataset
Motif DE_48h DE_48h-Foxl2_MA1607.2 10 bp overlap
GABPA 2 datasets
ChIP VCaP GSE49091.GABPA.VCaP 145 bp overlap
ChIP VCaP_ETOH GSE49091.GABPA.VCaP_ETOH 225 bp overlap
GATA2 1 dataset
Motif DE_12h DE_12h-GATA2_MA0036.4 7 bp overlap
GATA3 1 dataset
ChIP T-47D_sc GSE122847.GATA3.T-47D_sc 196 bp overlap
GATA4 6 datasets
ChIP DE DE-GATA4-1 804 bp overlap
ChIP DE DE-GATA4-2 928 bp overlap
Motif DE_12h DE_12h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 492 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 664 bp overlap
GATA6 14 datasets
ChIP DE DE-GATA6-1 1028 bp overlap
ChIP DE DE-GATA6-2 823 bp overlap
Motif DE_12h DE_12h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 278 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 605 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 561 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 302 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 617 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 676 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 433 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 580 bp overlap
ChIP foregut GSE117136.GATA6.foregut 508 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 255 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 405 bp overlap
GFI1 1 dataset
Motif DE_48h DE_48h-GFI1_MA0038.3 11 bp overlap
GSC 1 dataset
Motif ES_0h ES_0h-GSC_MA0648.2 6 bp overlap
GSC2 1 dataset
Motif ES_0h ES_0h-GSC2_MA0891.2 6 bp overlap
Gata3 1 dataset
Motif DE_12h DE_12h-Gata3_MA0037.5 8 bp overlap
HDAC1 1 dataset
ChIP PC-3 GSE147455.HDAC1.PC-3 191 bp overlap
HIC2 4 datasets
Motif DE_12h DE_12h-HIC2_MA0738.2 6 bp overlap
Motif DE_36h DE_36h-HIC2_MA0738.2 6 bp overlap
Motif DE_48h DE_48h-HIC2_MA0738.2 6 bp overlap
Motif ES_0h ES_0h-HIC2_MA0738.2 6 bp overlap
Hoxd13 1 dataset
Motif ES_0h ES_0h-Hoxd13_MA0909.4 7 bp overlap
IKZF1 2 datasets
Motif DE_12h DE_12h-IKZF1_MA1508.2 8 bp overlap
Motif DE_36h DE_36h-IKZF1_MA1508.2 8 bp overlap
ISL2 1 dataset
Motif DE_12h DE_12h-ISL2_MA0914.2 6 bp overlap
MAFK 3 datasets
Motif DE_12h DE_12h-MAFK_MA0496.4 10 bp overlap
Motif DE_36h DE_36h-MAFK_MA0496.4 10 bp overlap
Motif DE_48h DE_48h-MAFK_MA0496.4 10 bp overlap
MED1 1 dataset
ChIP HCT-116_thaps GSE121798.MED1.HCT-116_thaps 140 bp overlap
MED25 2 datasets
ChIP PC-3_FLAG GSE133445.MED25.PC-3_FLAG 321 bp overlap
ChIP PC-3_FLAG GSE133445.MED25.PC-3_FLAG 352 bp overlap
MEIS1 1 dataset
Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap
MGA::EVX1 1 dataset
Motif DE_48h DE_48h-MGAEVX1_MA1960.2 11 bp overlap
MITF 4 datasets
Motif DE_12h DE_12h-MITF_MA0620.4 10 bp overlap
Motif DE_36h DE_36h-MITF_MA0620.4 10 bp overlap
Motif DE_48h DE_48h-MITF_MA0620.4 10 bp overlap
Motif ES_0h ES_0h-MITF_MA0620.4 10 bp overlap
MXI1 4 datasets
Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap
Motif DE_36h DE_36h-MXI1_MA1108.3 6 bp overlap
Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap
Motif ES_0h ES_0h-MXI1_MA1108.3 6 bp overlap
MYB 4 datasets
Motif DE_12h DE_12h-MYB_MA0100.4 6 bp overlap
Motif DE_36h DE_36h-MYB_MA0100.4 6 bp overlap
Motif DE_48h DE_48h-MYB_MA0100.4 6 bp overlap
Motif ES_0h ES_0h-MYB_MA0100.4 6 bp overlap
NANOG 2 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 268 bp overlap
ChIP HUES-8 GSE109524.NANOG.HUES-8 253 bp overlap
NELFE 1 dataset
ChIP HeLa_DOX GSE125534.NELFE.HeLa_DOX 153 bp overlap
NFE2 1 dataset
Motif DE_36h DE_36h-NFE2_MA0841.2 10 bp overlap
NFYA 1 dataset
Motif DE_12h DE_12h-NFYA_MA0060.4 8 bp overlap
NFYC 1 dataset
Motif DE_12h DE_12h-NFYC_MA1644.2 7 bp overlap
NR1D2 1 dataset
Motif ES_0h ES_0h-NR1D2_MA1532.2 15 bp overlap
NR3C1 1 dataset
ChIP SUP-B15_DEX GSE107584.NR3C1.SUP-B15_DEX 151 bp overlap
Nkx3-2 1 dataset
Motif DE_12h DE_12h-Nkx3-2_MA0122.4 10 bp overlap
OTX1 1 dataset
Motif ES_0h ES_0h-OTX1_MA0711.2 6 bp overlap
PITX1 1 dataset
Motif ES_0h ES_0h-PITX1_MA0682.3 6 bp overlap
PITX3 1 dataset
Motif ES_0h ES_0h-PITX3_MA0714.2 6 bp overlap
PLAG1 3 datasets
Motif DE_12h DE_12h-PLAG1_MA0163.1 14 bp overlap
Motif DE_48h DE_48h-PLAG1_MA0163.1 14 bp overlap
Motif ES_0h ES_0h-PLAG1_MA0163.1 14 bp overlap
POLR2A 5 datasets
ChIP GM23338 ENCFF450WCS 491 bp overlap
ChIP H1 ENCFF566JSR 78 bp overlap
ChIP H1 ENCFF566JSR 334 bp overlap
ChIP H1 ENCFF566JSR 540 bp overlap
ChIP H1 ENCFF833NJP 265 bp overlap
POU2F1 1 dataset
Motif DE_48h DE_48h-POU2F1_MA0785.2 9 bp overlap
POU2F3 2 datasets
Motif DE_48h DE_48h-POU2F3_MA0627.3 9 bp overlap
Motif DE_48h DE_48h-POU2F3_MA0627.3 9 bp overlap
POU3F4 1 dataset
Motif DE_48h DE_48h-POU3F4_MA0789.1 9 bp overlap
POU4F1 1 dataset
Motif DE_48h DE_48h-POU4F1_MA0790.2 12 bp overlap
POU4F2 1 dataset
Motif DE_48h DE_48h-POU4F2_MA0683.2 15 bp overlap
POU4F3 1 dataset
Motif DE_48h DE_48h-POU4F3_MA0791.2 12 bp overlap
POU5F1 8 datasets
Motif DE_48h DE_48h-POU5F1_MA1115.2 7 bp overlap
Motif DE_48h DE_48h-POU5F1_MA1115.2 7 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 207 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 398 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 386 bp overlap
ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 485 bp overlap
ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 223 bp overlap
ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 323 bp overlap
POU5F1B 1 dataset
Motif DE_48h DE_48h-POU5F1B_MA0792.1 9 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 267 bp overlap
Pparg::Rxra 3 datasets
Motif DE_12h DE_12h-PpargRxra_MA0065.3 13 bp overlap
Motif DE_48h DE_48h-PpargRxra_MA0065.3 13 bp overlap
Motif ES_0h ES_0h-PpargRxra_MA0065.3 13 bp overlap
RAD21 1 dataset
ChIP hiPSC_CVI GSE106870.RAD21.hiPSC_CVI 130 bp overlap
RARA 1 dataset
Motif DE_36h DE_36h-RARA_MA0729.1 18 bp overlap
RHOXF1 1 dataset
Motif ES_0h ES_0h-RHOXF1_MA0719.2 6 bp overlap
RORA 1 dataset
Motif DE_36h DE_36h-RORA_MA0072.2 11 bp overlap
Rarg 1 dataset
Motif DE_36h DE_36h-Rarg_MA0860.1 17 bp overlap
SCRT1 1 dataset
Motif ES_0h ES_0h-SCRT1_MA0743.3 10 bp overlap
SCRT2 1 dataset
Motif ES_0h ES_0h-SCRT2_MA0744.3 10 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 357 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 647 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 423 bp overlap
SMARCA4 1 dataset
ChIP hiPSC GSE124903.SMARCA4.hiPSC 167 bp overlap
SNAI1 1 dataset
Motif ES_0h ES_0h-SNAI1_MA1558.2 7 bp overlap
SOX13 1 dataset
Motif DE_36h DE_36h-SOX13_MA1120.2 7 bp overlap
SOX17 2 datasets
ChIP DE_D2 DED2-SOX17_Batch_II 511 bp overlap
ChIP DE_D2 DED2-SOX17_Batch_II 237 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 862 bp overlap
SOX2 1 dataset
Motif DE_36h DE_36h-SOX2_MA0143.5 7 bp overlap
SPI1 1 dataset
ChIP KG-1 GSE128834.SPI1.KG-1 188 bp overlap
Sox17 1 dataset
Motif DE_36h DE_36h-Sox17_MA0078.3 10 bp overlap
Sox3 1 dataset
Motif DE_36h DE_36h-Sox3_MA0514.3 7 bp overlap
Sox5 1 dataset
Motif DE_36h DE_36h-Sox5_MA0087.3 8 bp overlap
Sox6 1 dataset
Motif DE_36h DE_36h-Sox6_MA0515.1 10 bp overlap
Sox7 1 dataset
Motif DE_36h DE_36h-Sox7_MA2095.1 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 363 bp overlap
TBR1 1 dataset
Motif ES_0h ES_0h-TBR1_MA0802.2 9 bp overlap
TBX18 1 dataset
Motif ES_0h ES_0h-TBX18_MA1565.2 9 bp overlap
TBX2 1 dataset
Motif ES_0h ES_0h-TBX2_MA0688.2 9 bp overlap
TBX3 1 dataset
Motif ES_0h ES_0h-TBX3_MA1566.3 9 bp overlap
TCF12 1 dataset
Motif ES_0h ES_0h-TCF12_MA1648.2 7 bp overlap
TCF21 1 dataset
ChIP HCASMC GSE124011.TCF21.HCASMC 180 bp overlap
TCF3 1 dataset
Motif ES_0h ES_0h-TCF3_MA0522.4 7 bp overlap
TFAP2C 2 datasets
ChIP HCC1954 GSE126897.TFAP2C.HCC1954 309 bp overlap
ChIP HCC1954 GSE126897.TFAP2C.HCC1954 421 bp overlap
TFE3 4 datasets
Motif DE_12h DE_12h-TFE3_MA0831.3 10 bp overlap
Motif DE_36h DE_36h-TFE3_MA0831.3 10 bp overlap
Motif DE_48h DE_48h-TFE3_MA0831.3 10 bp overlap
Motif ES_0h ES_0h-TFE3_MA0831.3 10 bp overlap
TFEB 4 datasets
Motif DE_12h DE_12h-TFEB_MA0692.2 8 bp overlap
Motif DE_36h DE_36h-TFEB_MA0692.2 8 bp overlap
Motif DE_48h DE_48h-TFEB_MA0692.2 8 bp overlap
Motif ES_0h ES_0h-TFEB_MA0692.2 8 bp overlap
TFEC 4 datasets
Motif DE_12h DE_12h-TFEC_MA0871.3 8 bp overlap
Motif DE_36h DE_36h-TFEC_MA0871.3 8 bp overlap
Motif DE_48h DE_48h-TFEC_MA0871.3 8 bp overlap
Motif ES_0h ES_0h-TFEC_MA0871.3 8 bp overlap
TRIM28 1 dataset
ChIP hESC GSE115387.TRIM28.hESC 204 bp overlap
TRPS1 1 dataset
Motif DE_12h DE_12h-TRPS1_MA1970.2 8 bp overlap
Tbx6 1 dataset
Motif ES_0h ES_0h-Tbx6_MA1567.3 9 bp overlap
USF1 6 datasets
Motif DE_12h DE_12h-USF1_MA0093.4 10 bp overlap
Motif DE_36h DE_36h-USF1_MA0093.4 10 bp overlap
Motif DE_48h DE_48h-USF1_MA0093.4 10 bp overlap
Motif ES_0h ES_0h-USF1_MA0093.4 10 bp overlap
ChIP H1 ENCFF090WVU 241 bp overlap
ChIP WA01 ENCSR000BIU.USF1.WA01 192 bp overlap
ZEB1 3 datasets
Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap
Motif ES_0h ES_0h-ZEB1_MA0103.4 6 bp overlap
Motif ES_0h ES_0h-ZEB1_MA0103.4 6 bp overlap
ZMAT4 1 dataset
ChIP WTC11 ENCFF608UXZ 241 bp overlap
ZNF143 3 datasets
ChIP WA09 GSE105028.ZNF143.WA09 213 bp overlap
ChIP WA09_heat-shock GSE105028.ZNF143.WA09_heat-shock 234 bp overlap
ChIP WA09_heat-shock GSE105028.ZNF143.WA09_heat-shock 188 bp overlap
ZNF189 3 datasets
Motif DE_12h DE_12h-ZNF189_MA1725.2 9 bp overlap
Motif DE_36h DE_36h-ZNF189_MA1725.2 9 bp overlap
Motif DE_48h DE_48h-ZNF189_MA1725.2 9 bp overlap
ZNF214 3 datasets
Motif DE_12h DE_12h-ZNF214_MA1975.2 13 bp overlap
Motif DE_36h DE_36h-ZNF214_MA1975.2 13 bp overlap
Motif DE_48h DE_48h-ZNF214_MA1975.2 13 bp overlap
ZNF341 3 datasets
Motif DE_12h DE_12h-ZNF341_MA1655.2 8 bp overlap
Motif DE_36h DE_36h-ZNF341_MA1655.2 8 bp overlap
Motif DE_48h DE_48h-ZNF341_MA1655.2 8 bp overlap
ZNF425 1 dataset
ChIP WTC11 ENCFF359IXT 301 bp overlap
ZNF462 1 dataset
ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 118 bp overlap
ZNF512B 1 dataset
ChIP MCF-7 ENCSR761LRR.ZNF512B.MCF-7 232 bp overlap
ZNF610 1 dataset
Motif DE_12h DE_12h-ZNF610_MA1713.2 10 bp overlap
ZNF708 3 datasets
Motif DE_12h DE_12h-ZNF708_MA1730.2 9 bp overlap
Motif DE_36h DE_36h-ZNF708_MA1730.2 9 bp overlap
Motif DE_48h DE_48h-ZNF708_MA1730.2 9 bp overlap
Zic1::Zic2 1 dataset
Motif ES_0h ES_0h-Zic1Zic2_MA1628.2 7 bp overlap
Zic3 1 dataset
Motif ES_0h ES_0h-Zic3_MA0697.3 7 bp overlap
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