chr3 : 37,375,227 – 37,375,671

444 bp 78 TFs 1 linked gene

This 444 bp open chromatin element is linked to APRG1 and is bound by 78 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
APRG1		9.9 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

78 transcription factors

AR 1 dataset

ChIP LNCaP GSE80256.AR.LNCaP 318 bp overlap

ATF4 1 dataset

Motif DE_12h DE_12h-ATF4_MA0833.3 10 bp overlap

BRD4 1 dataset

ChIP HEK293_Ctrl GSE129407.BRD4.HEK293_Ctrl 225 bp overlap

CEBPB 2 datasets

ChIP H1 ENCFF871PTR 208 bp overlap

ChIP WA01 ENCSR000EBV.CEBPB.WA01 157 bp overlap

CEBPD 1 dataset

Motif DE_12h DE_12h-CEBPD_MA0836.3 8 bp overlap

CEBPG 1 dataset

Motif DE_12h DE_12h-CEBPG_MA1636.2 10 bp overlap

CTCF 1 dataset

ChIP T-47D_NaCl-triptolide GSE111923.CTCF.T-47D_NaCl-triptolide 266 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF262VBH 270 bp overlap

ChIP BLaER1 ENCFF274GAT 264 bp overlap

E2F6 1 dataset

Motif DE_12h DE_12h-E2F6_MA0471.3 8 bp overlap

EED 1 dataset

ChIP ProEs GSE59087.EED.ProEs 146 bp overlap

FEZF2 1 dataset

Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap

FOXD2 1 dataset

Motif DE_12h DE_12h-FOXD2_MA0847.4 11 bp overlap

HLF 1 dataset

Motif DE_12h DE_12h-HLF_MA0043.4 9 bp overlap

Hand1 1 dataset

Motif DE_12h DE_12h-Hand1_MA2123.1 9 bp overlap

IFNA1 1 dataset

ChIP Huh-7_GFP GSE110511.IFNA1.Huh-7_GFP 329 bp overlap

KLF14 1 dataset

Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap

KLF16 1 dataset

Motif DE_12h DE_12h-KLF16_MA0741.1 11 bp overlap

KLF5 1 dataset

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

MAZ 1 dataset

Motif DE_12h DE_12h-MAZ_MA1522.2 8 bp overlap

MED1 1 dataset

ChIP SGBS GSE64233.MED1.SGBS 55 bp overlap

MEIS1 1 dataset

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

MSC 1 dataset

Motif DE_12h DE_12h-MSC_MA0665.1 10 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 207 bp overlap

NCAPH2 2 datasets

ChIP IMR-90_FLAG_G GSE118494.NCAPH2.IMR-90_FLAG_G 133 bp overlap

ChIP IMR-90_FLAG_OIS GSE118494.NCAPH2.IMR-90_FLAG_OIS 347 bp overlap

NFIA 1 dataset

Motif DE_12h DE_12h-NFIA_MA0670.2 6 bp overlap

NFIL3 1 dataset

Motif DE_12h DE_12h-NFIL3_MA0025.3 9 bp overlap

NFIX 1 dataset

Motif DE_12h DE_12h-NFIX_MA0671.2 6 bp overlap

NR1H2::RXRA 1 dataset

Motif DE_12h DE_12h-NR1H2RXRA_MA0115.1 17 bp overlap

NR2C2 1 dataset

ChIP K562 ENCFF750AXF 198 bp overlap

Nr5A2 1 dataset

Motif DE_12h DE_12h-Nr5A2_MA0505.3 9 bp overlap

PAX3 1 dataset

Motif DE_12h DE_12h-PAX3_MA1546.2 14 bp overlap

POLR2A 1 dataset

ChIP GM12878 ENCFF521FXC 383 bp overlap

POU1F1 1 dataset

Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap

POU2F1 1 dataset

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 1 dataset

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU4F1 1 dataset

Motif DE_12h DE_12h-POU4F1_MA0790.2 12 bp overlap

POU4F2 2 datasets

Motif DE_12h DE_12h-POU4F2_MA0683.2 15 bp overlap

ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 126 bp overlap

POU4F3 1 dataset

Motif DE_12h DE_12h-POU4F3_MA0791.2 12 bp overlap

POU5F1 6 datasets

Motif DE_12h DE_12h-POU5F1_MA1115.2 7 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 400 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 254 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 377 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 352 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 265 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

RBM22 1 dataset

ChIP K562 ENCFF629OUL 149 bp overlap

RUNX1 1 dataset

ChIP K-562 ENCSR588AKU.RUNX1.K-562 122 bp overlap

Rarb 1 dataset

Motif DE_12h DE_12h-Rarb_MA0857.1 16 bp overlap

SALL2 1 dataset

ChIP HEK293 GSE145940.SALL2.HEK293 192 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 268 bp overlap

SP3 1 dataset

Motif DE_12h DE_12h-SP3_MA0746.3 11 bp overlap

SP4 1 dataset

Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap

SP5 1 dataset

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

Spz1 1 dataset

Motif DE_12h DE_12h-Spz1_MA0111.1 11 bp overlap

TERF1 1 dataset

ChIP LCL GSE55053.TERF1.LCL 147 bp overlap

TFAP2B 1 dataset

Motif DE_12h DE_12h-TFAP2B_MA0813.1 13 bp overlap

TFAP2C 2 datasets

Motif DE_12h DE_12h-TFAP2C_MA0815.1 13 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 263 bp overlap

TRIM28 1 dataset

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 418 bp overlap

YY1 1 dataset

ChIP NT2-D1 ENCSR000EXG.YY1.NT2-D1 181 bp overlap

ZFP42 1 dataset

Motif DE_12h DE_12h-ZFP42_MA1651.2 13 bp overlap

ZNF148 1 dataset

Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap

ZNF16 1 dataset

Motif DE_12h DE_12h-ZNF16_MA1654.2 21 bp overlap

ZNF184 1 dataset

Motif DE_12h DE_12h-ZNF184_MA2120.1 13 bp overlap

ZNF213 1 dataset

Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap

ZNF324 1 dataset

Motif DE_12h DE_12h-ZNF324_MA1977.2 14 bp overlap

ZNF354A 1 dataset

Motif DE_12h DE_12h-ZNF354A_MA1978.2 20 bp overlap

ZNF417 1 dataset

ChIP WA01 GSE144149.ZNF417.WA01 291 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 242 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 158 bp overlap

ZNF501 1 dataset

ChIP Hep-G2 ENCSR227PHM.ZNF501.Hep-G2 198 bp overlap

ZNF528 1 dataset

Motif DE_12h DE_12h-ZNF528_MA1597.1 17 bp overlap

ZNF547 1 dataset

Motif DE_12h DE_12h-ZNF547_MA2334.1 13 bp overlap

ZNF572 1 dataset

ChIP Hep-G2 ENCSR663CTC.ZNF572.Hep-G2 157 bp overlap

ZNF582 1 dataset

Motif DE_12h DE_12h-ZNF582_MA1983.2 19 bp overlap

ZNF585B 2 datasets

ChIP HEK293 ENCFF657XIZ 96 bp overlap

ChIP HEK293 ENCSR011XCI.ZNF585B.HEK293 317 bp overlap

ZNF675 1 dataset

Motif DE_12h DE_12h-ZNF675_MA1714.2 19 bp overlap

ZNF707 1 dataset

Motif DE_12h DE_12h-ZNF707_MA1715.1 15 bp overlap