chr2:130,144,783–130,145,418

chr2 : 130,144,783 – 130,145,418

635 bp 89 TFs 7 linked genes

This 635 bp open chromatin element is linked to 7 target genes and is bound by 89 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
CCDC74B		at TSS	At TSS	Proximity
POTEF		15.9 kb	Distal	Multiome
SMPD4		36.5 kb	Distal	Multiome
MZT2B		37.1 kb	Distal	Multiome
CCDC115		197.6 kb	Distal	Multiome
IMP4		197.8 kb	Distal	Multiome
PTPN18		210.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

89 transcription factors

ARID4A 2 datasets

ChIP HepG2 ENCFF142DIE 434 bp overlap

ChIP HepG2 ENCFF142DIE 635 bp overlap

ATF6 3 datasets

Motif DE_12h DE_12h-ATF6_MA1466.2 13 bp overlap

Motif DE_60h DE_60h-ATF6_MA1466.2 13 bp overlap

Motif DE_72h DE_72h-ATF6_MA1466.2 13 bp overlap

COMMD3-BMI1,BMI1 2 datasets

ChIP GM12878 ENCFF249AMT 118 bp overlap

ChIP MCF-7 ENCFF570JPP 216 bp overlap

CREB3L1 3 datasets

Motif DE_12h DE_12h-CREB3L1_MA0839.2 13 bp overlap

Motif DE_60h DE_60h-CREB3L1_MA0839.2 13 bp overlap

Motif DE_72h DE_72h-CREB3L1_MA0839.2 13 bp overlap

CTCF 6 datasets

ChIP HepG2 ENCFF757EKU 351 bp overlap

ChIP MM1-S GSE43743.CTCF.MM1-S 150 bp overlap

ChIP chondrocyte ENCFF134ORZ 356 bp overlap

ChIP chondrocyte ENCFF134ORZ 580 bp overlap

ChIP dorsolateral prefrontal cortex ENCFF433UFM 545 bp overlap

ChIP neural cell ENCFF335ADI 505 bp overlap

CTCFL 1 dataset

ChIP K-562 GSE70764.CTCFL.K-562 161 bp overlap

CXXC5 1 dataset

ChIP K562 ENCFF497CZN 561 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF093OYK 292 bp overlap

ChIP BLaER1 ENCFF364PUR 392 bp overlap

E2F1 4 datasets

ChIP HeLa-S3 ENCSR000EVM.E2F1.HeLa-S3 203 bp overlap

ChIP MCF-7 ENCFF692OYJ 617 bp overlap

ChIP MCF-7 ENCSR000EWX.E2F1.MCF-7 602 bp overlap

ChIP U-87MG_GBM GSE99171.E2F1.U-87MG_GBM 178 bp overlap

E2F4 2 datasets

ChIP HepG2 ENCFF311TOD 471 bp overlap

ChIP HepG2 ENCFF311TOD 333 bp overlap

EGR1 8 datasets

Motif DE_60h DE_60h-EGR1_MA0162.5 10 bp overlap

ChIP GM12878 ENCFF092DJY 211 bp overlap

ChIP HCT116 ENCFF456NPQ 465 bp overlap

ChIP HepG2 ENCFF674RQO 273 bp overlap

ChIP K-562 ENCSR000BNE.EGR1.K-562 105 bp overlap

ChIP K562 ENCFF006PJY 245 bp overlap

ChIP K562 ENCFF113OPQ 145 bp overlap

ChIP K562 ENCFF895KGN 155 bp overlap

Motif DE_60h DE_60h-EGR2_MA0472.2 11 bp overlap

Motif DE_60h DE_60h-EGR3_MA0732.2 11 bp overlap

Motif DE_60h DE_60h-EGR4_MA0733.2 11 bp overlap

ELF1 7 datasets

ChIP GM12878 ENCFF432UGA 365 bp overlap

ChIP GM12878 ENCFF692SMY 457 bp overlap

ChIP HepG2 ENCFF367ZWV 421 bp overlap

ChIP HepG2 ENCFF838BCU 277 bp overlap

ChIP K-562 ENCSR000BMD.ELF1.K-562 117 bp overlap

ChIP K562 ENCFF496AKI 277 bp overlap

ChIP MCF-7 ENCFF687CWI 391 bp overlap

ESR1 8 datasets

ChIP Ishikawa_C2-3 GSE147141.ESR1.Ishikawa_C2-3 375 bp overlap

ChIP MCF-7 GSE48930.ESR1.MCF-7 175 bp overlap

ChIP MDA-MB-134-VI_E2 GSE109103.ESR1.MDA-MB-134-VI_E2 230 bp overlap

ChIP MDA-MB-134-VI_FI GSE109103.ESR1.MDA-MB-134-VI_FI 176 bp overlap

ChIP U2OS_100nM-E2 GSE151039.ESR1.U2OS_100nM-E2 243 bp overlap

ChIP U2OS_10nM-E2 GSE151039.ESR1.U2OS_10nM-E2 260 bp overlap

ChIP U2OS_10nM-E2-B GSE151039.ESR1.U2OS_10nM-E2-B 239 bp overlap

ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 223 bp overlap

GABPB1 1 dataset

ChIP HepG2 ENCFF315AWN 581 bp overlap

GFI1 2 datasets

Motif DE_60h DE_60h-GFI1_MA0038.3 11 bp overlap

ChIP HepG2 ENCFF472INF 557 bp overlap

GLIS1 1 dataset

ChIP HEK293 ENCFF299RSE 122 bp overlap

Gfi1B 1 dataset

Motif DE_60h DE_60h-Gfi1B_MA0483.2 10 bp overlap

HMGA2 1 dataset

ChIP WTC11 ENCFF535JLP 145 bp overlap

HNF1B 1 dataset

Motif DE_60h DE_60h-HNF1B_MA0153.2 13 bp overlap

HOXA10 1 dataset

ChIP HepG2 ENCFF422LBU 557 bp overlap

HOXA3 1 dataset

ChIP HepG2 ENCFF374TCI 477 bp overlap

HOXC10 1 dataset

ChIP HEK293 ENCFF467BQB 499 bp overlap

HOXC13 1 dataset

Motif DE_60h DE_60h-HOXC13_MA0907.2 9 bp overlap

IKZF3 1 dataset

ChIP HEK293 ENCFF518OXG 371 bp overlap

Motif DE_60h DE_60h-KLF1_MA0493.3 8 bp overlap

KLF10 1 dataset

Motif DE_60h DE_60h-KLF10_MA1511.2 9 bp overlap

KLF11 1 dataset

Motif DE_60h DE_60h-KLF11_MA1512.2 10 bp overlap

KLF12 1 dataset

Motif DE_60h DE_60h-KLF12_MA0742.2 9 bp overlap

KLF14 1 dataset

Motif DE_60h DE_60h-KLF14_MA0740.2 9 bp overlap

KLF15 1 dataset

Motif DE_60h DE_60h-KLF15_MA1513.2 8 bp overlap

KLF16 1 dataset

Motif DE_60h DE_60h-KLF16_MA0741.1 11 bp overlap

Motif DE_60h DE_60h-KLF2_MA1515.2 8 bp overlap

Motif DE_60h DE_60h-KLF3_MA1516.2 10 bp overlap

Motif DE_60h DE_60h-KLF4_MA0039.5 8 bp overlap

Motif DE_60h DE_60h-KLF5_MA0599.1 10 bp overlap

Motif DE_60h DE_60h-KLF7_MA1959.2 8 bp overlap

KLF9 2 datasets

Motif DE_60h DE_60h-KLF9_MA1107.3 11 bp overlap

ChIP HEK293 ENCFF588INF 436 bp overlap

ChIP HepG2 ENCFF507HCX 617 bp overlap

ChIP HepG2 ENCFF507HCX 429 bp overlap

MEIS2 1 dataset

ChIP K562 ENCFF320GSD 308 bp overlap

NFATC3 3 datasets

Motif DE_12h DE_12h-NFATC3_MA0625.3 6 bp overlap

Motif DE_60h DE_60h-NFATC3_MA0625.3 6 bp overlap

Motif DE_72h DE_72h-NFATC3_MA0625.3 6 bp overlap

NFATC4 3 datasets

Motif DE_12h DE_12h-NFATC4_MA1525.3 9 bp overlap

Motif DE_60h DE_60h-NFATC4_MA1525.3 9 bp overlap

Motif DE_72h DE_72h-NFATC4_MA1525.3 9 bp overlap

ChIP K562 ENCFF791UHF 561 bp overlap

Nfatc1 3 datasets

Motif DE_12h DE_12h-Nfatc1_MA0624.3 6 bp overlap

Motif DE_60h DE_60h-Nfatc1_MA0624.3 6 bp overlap

Motif DE_72h DE_72h-Nfatc1_MA0624.3 6 bp overlap

Nfatc2 3 datasets

Motif DE_12h DE_12h-Nfatc2_MA0152.3 8 bp overlap

Motif DE_60h DE_60h-Nfatc2_MA0152.3 8 bp overlap

Motif DE_72h DE_72h-Nfatc2_MA0152.3 8 bp overlap

PATZ1 2 datasets

Motif DE_60h DE_60h-PATZ1_MA1961.2 11 bp overlap

ChIP HepG2 ENCFF723PFC 401 bp overlap

ChIP K562 ENCFF286KMN 408 bp overlap

ChIP SK-N-SH ENCFF876BMC 317 bp overlap

ChIP A549 ENCFF815XUD 401 bp overlap

PKNOX1 2 datasets

ChIP HEK293T ENCFF174WDB 309 bp overlap

ChIP K562 ENCFF236IUS 427 bp overlap

POLR2A 3 datasets

ChIP A549 ENCFF748RAW 311 bp overlap

ChIP HCT116 ENCFF508RDJ 417 bp overlap

ChIP thyroid gland ENCFF979LRR 183 bp overlap

POLR2G 4 datasets

ChIP K562 ENCFF047BLG 382 bp overlap

ChIP K562 ENCFF047BLG 185 bp overlap

ChIP K562 ENCFF648YPL 382 bp overlap

ChIP K562 ENCFF648YPL 625 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 539 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 582 bp overlap

Prdm4 3 datasets

Motif DE_12h DE_12h-Prdm4_MA1647.3 11 bp overlap

Motif DE_60h DE_60h-Prdm4_MA1647.3 11 bp overlap

Motif DE_72h DE_72h-Prdm4_MA1647.3 11 bp overlap

RBM39 2 datasets

ChIP HepG2 ENCFF801JUH 427 bp overlap

ChIP HepG2 ENCFF801JUH 635 bp overlap

RFX1 9 datasets

Motif DE_12h DE_12h-RFX1_MA0509.3 16 bp overlap

Motif DE_60h DE_60h-RFX1_MA0509.3 16 bp overlap

Motif DE_72h DE_72h-RFX1_MA0509.3 16 bp overlap

ChIP HepG2 ENCFF144SCF 202 bp overlap

ChIP K562 ENCFF421AVO 589 bp overlap

ChIP K562 ENCFF809XVG 493 bp overlap

ChIP MCF-7 ENCFF782EZS 561 bp overlap

ChIP MCF-7 ENCFF973QAD 540 bp overlap

ChIP MCF-7 ENCFF973QAD 542 bp overlap

RFX2 3 datasets

Motif DE_12h DE_12h-RFX2_MA0600.3 14 bp overlap

Motif DE_60h DE_60h-RFX2_MA0600.3 14 bp overlap

Motif DE_72h DE_72h-RFX2_MA0600.3 14 bp overlap

RFX3 4 datasets

Motif DE_12h DE_12h-RFX3_MA0798.3 16 bp overlap

Motif DE_60h DE_60h-RFX3_MA0798.3 16 bp overlap

Motif DE_72h DE_72h-RFX3_MA0798.3 16 bp overlap

ChIP HepG2 ENCFF681ZHO 171 bp overlap

RFX5 3 datasets

Motif DE_12h DE_12h-RFX5_MA0510.3 14 bp overlap

Motif DE_60h DE_60h-RFX5_MA0510.3 14 bp overlap

Motif DE_72h DE_72h-RFX5_MA0510.3 14 bp overlap

SALL1 1 dataset

ChIP HepG2 ENCFF426MCK 497 bp overlap

SAP130 1 dataset

ChIP HepG2 ENCFF892EHZ 277 bp overlap

SIN3A 1 dataset

ChIP Hep-G2 ENCSR000BGL.SIN3A.Hep-G2 92 bp overlap

SMAD4 1 dataset

ChIP K562 ENCFF628RBP 541 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 346 bp overlap

Motif DE_60h DE_60h-SP1_MA0079.5 9 bp overlap

Motif DE_60h DE_60h-SP2_MA0516.3 9 bp overlap

ChIP HEK293 ENCFF181QXT 233 bp overlap

Motif DE_60h DE_60h-SP3_MA0746.3 11 bp overlap

Motif DE_60h DE_60h-SP4_MA0685.2 9 bp overlap

Motif DE_60h DE_60h-SP9_MA1564.2 10 bp overlap

ChIP Ishikawa ENCFF271ZVL 491 bp overlap

Motif DE_60h DE_60h-Wt1_MA1627.2 10 bp overlap

ChIP Ishikawa ENCFF505XQX 218 bp overlap

ZBTB8A 1 dataset

ChIP HEK293 ENCFF303WRD 630 bp overlap

ZGPAT 1 dataset

ChIP HepG2 ENCFF055YSO 586 bp overlap

ZNF148 1 dataset

Motif DE_60h DE_60h-ZNF148_MA1653.2 10 bp overlap

ZNF281 1 dataset

Motif DE_60h DE_60h-ZNF281_MA1630.3 10 bp overlap

ZNF335 2 datasets

ChIP HEK293 ENCFF784SLD 451 bp overlap

ChIP HEK293 ENCSR328SUD.ZNF335.HEK293 153 bp overlap

ZNF341 1 dataset

ChIP HEK293 ENCFF944VMC 425 bp overlap

ZNF394 2 datasets

ChIP HEK293 ENCFF236OPX 303 bp overlap

ChIP HEK293 ENCSR125DNC.ZNF394.HEK293 187 bp overlap

ZNF417 4 datasets

Motif DE_12h DE_12h-ZNF417_MA1727.2 7 bp overlap

Motif DE_12h DE_12h-ZNF417_MA1727.2 7 bp overlap

Motif DE_60h DE_60h-ZNF417_MA1727.2 7 bp overlap

Motif DE_72h DE_72h-ZNF417_MA1727.2 7 bp overlap

ZNF423 1 dataset

ChIP HEK293 ENCFF937QHI 357 bp overlap

ZNF530 3 datasets

Motif DE_12h DE_12h-ZNF530_MA1981.2 14 bp overlap

Motif DE_60h DE_60h-ZNF530_MA1981.2 14 bp overlap

Motif DE_72h DE_72h-ZNF530_MA1981.2 14 bp overlap

ZNF682 1 dataset

Motif DE_60h DE_60h-ZNF682_MA1599.2 11 bp overlap

ZNF687 2 datasets

ChIP HepG2 ENCFF653WIX 447 bp overlap

ChIP HepG2 ENCFF653WIX 396 bp overlap

Zfp961 4 datasets

Motif DE_12h DE_12h-Zfp961_MA2126.1 8 bp overlap

Motif DE_12h DE_12h-Zfp961_MA2126.1 8 bp overlap

Motif DE_60h DE_60h-Zfp961_MA2126.1 8 bp overlap

Motif DE_72h DE_72h-Zfp961_MA2126.1 8 bp overlap

Motif DE_60h DE_60h-Zfx_MA0146.3 10 bp overlap