chr1:31,776,109–31,776,832

chr1 : 31,776,109 – 31,776,832

723 bp 86 TFs 6 linked genes

This 723 bp open chromatin element is linked to 6 target genes and is bound by 86 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
SPOCD1		39.5 kb	Distal	Multiome
PEF1		131.7 kb	Distal	Multiome
PTP4A2		161.8 kb	Distal	Multiome
KHDRBS1		237.3 kb	Distal	Multiome
TMEM39B		296.4 kb	Distal	Multiome
ENSG00000203325		296.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

86 transcription factors

ChIP LNCaP_ETOH GSE69043.AR.LNCaP_ETOH 140 bp overlap

ChIP LNCaP_FOXA1 ERP003503.AR.LNCaP_FOXA1 162 bp overlap

ChIP LNCaP_R1881 GSE69043.AR.LNCaP_R1881 133 bp overlap

ChIP LNCaP_SHGATA2_R1881 GSE69043.AR.LNCaP_SHGATA2_R1881 107 bp overlap

ChIP metastatic-neuroblastoma_SKNMM GSE100148.ATRX.metastatic-neuroblastoma_SKNMM 235 bp overlap

ChIP UM-RC-6 GSE101987.BAP1.UM-RC-6 356 bp overlap

BCL11A 2 datasets

ChIP HUDEP-2_90min GSE104676.BCL11A.HUDEP-2_90min 95 bp overlap

ChIP HUDEP-2_BCL11A-ER-V5 GSE103445.BCL11A.HUDEP-2_BCL11A-ER-V5 181 bp overlap

BRD4 7 datasets

ChIP BE2C GSE80151.BRD4.BE2C 206 bp overlap

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 142 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 672 bp overlap

ChIP RH4_shCHD4 GSE140115.BRD4.RH4_shCHD4 491 bp overlap

ChIP RH4_shscr GSE140115.BRD4.RH4_shscr 322 bp overlap

ChIP SK-N-BE2-C GSE80151.BRD4.SK-N-BE2-C 206 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 486 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 276 bp overlap

ChIP K562 ENCFF673OEZ 288 bp overlap

ChIP MM1-S_JQ1_500NM GSE42355.CDK9.MM1-S_JQ1_500NM 67 bp overlap

CEBPD 1 dataset

ChIP K-562 ENCSR000BVY.CEBPD.K-562 103 bp overlap

ChIP SK-N-SH ENCSR274SLQ.CHD2.SK-N-SH 128 bp overlap

CTBP1 1 dataset

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 312 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF031ISE 275 bp overlap

ChIP BLaER1 ENCFF262VBH 179 bp overlap

ChIP K-562 ENCSR000EWL.E2F4.K-562 161 bp overlap

EBF3_P177L 1 dataset

ChIP SK-N-SH GSE90682.EBF3_P177L.SK-N-SH 270 bp overlap

ChIP HEK293 ENCFF336LFH 96 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 369 bp overlap

EP300 2 datasets

ChIP SK-N-SH ENCFF829RWA 300 bp overlap

ChIP SK-N-SH ENCSR000EHV.EP300.SK-N-SH 253 bp overlap

ESR1 17 datasets

ChIP MCF-7 GSE48930.ESR1.MCF-7 202 bp overlap

ChIP MCF-7 GSE76893.ESR1.MCF-7 157 bp overlap

ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 190 bp overlap

ChIP MCF-7_E2 GSE108883.ESR1.MCF-7_E2 186 bp overlap

ChIP MCF-7_LTED_E2 GSE86538.ESR1.MCF-7_LTED_E2 103 bp overlap

ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 214 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 459 bp overlap

ChIP MCF-7_R5020 GSE68355.ESR1.MCF-7_R5020 209 bp overlap

ChIP MCF-7_SHCRT_E2 ERP000380.ESR1.MCF-7_SHCRT_E2 132 bp overlap

ChIP MCF-7_SICTR_E2 GSE40129.ESR1.MCF-7_SICTR_E2 111 bp overlap

ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 180 bp overlap

ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 186 bp overlap

ChIP MCF-7_parental GSE123284.ESR1.MCF-7_parental 192 bp overlap

ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 223 bp overlap

ChIP MDA-MB-134-VI_E2 GSE109103.ESR1.MDA-MB-134-VI_E2 274 bp overlap

ChIP MDA-MB-134-VI_FI GSE109103.ESR1.MDA-MB-134-VI_FI 230 bp overlap

ChIP T-47D_Y537S_E2 GSE148277.ESR1.T-47D_Y537S_E2 289 bp overlap

ESR1_Y537N 1 dataset

ChIP MCF-7_dox GSE94493.ESR1_Y537N.MCF-7_dox 176 bp overlap

ESR1_Y537S 2 datasets

ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 268 bp overlap

ChIP MCF-7_dox GSE94493.ESR1_Y537S.MCF-7_dox 194 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 261 bp overlap

FEZF2 1 dataset

Motif DE_36h DE_36h-FEZF2_MA2341.1 8 bp overlap

FOXA1 1 dataset

ChIP LNCaP_SHFOXA1_R1881 GSE37345.FOXA1.LNCaP_SHFOXA1_R1881 108 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 408 bp overlap

ChIP DE DE-FOXA2-2 329 bp overlap

FOXJ3 1 dataset

ChIP SK-N-SH ENCFF124KVL 346 bp overlap

GATA1 5 datasets

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 102 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 178 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 216 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 228 bp overlap

ChIP erythroid-progenitor_EPrec GSE124163.GATA1.erythroid-progenitor_EPrec 143 bp overlap

GATA2 13 datasets

ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 145 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 279 bp overlap

ChIP K562 ENCFF513FTZ 301 bp overlap

ChIP LNCaP GSE38391.GATA2.LNCaP 173 bp overlap

ChIP LNCaP GSE52725.GATA2.LNCaP 173 bp overlap

ChIP LNCaP_CSFCS GSE69043.GATA2.LNCaP_CSFCS 168 bp overlap

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 428 bp overlap

ChIP SH-SY5Y ENCFF485YIB 274 bp overlap

ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 497 bp overlap

ChIP SK-N-SH ENCFF764OZD 412 bp overlap

ChIP SK-N-SH ENCFF764OZD 417 bp overlap

ChIP SK-N-SH ENCSR706VOO.GATA2.SK-N-SH 305 bp overlap

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 248 bp overlap

GATA3 10 datasets

ChIP BE2C GSE65664.GATA3.BE2C 352 bp overlap

ChIP CLB-Ga GSE90683.GATA3.CLB-Ga 268 bp overlap

ChIP Jurkat GSE120063.GATA3.Jurkat 268 bp overlap

ChIP Jurkat GSE29180.GATA3.Jurkat 359 bp overlap

ChIP Kelly GSE65664.GATA3.Kelly 227 bp overlap

ChIP SH-SY5Y ENCFF475HYF 471 bp overlap

ChIP SH-SY5Y GSE65664.GATA3.SH-SY5Y 232 bp overlap

ChIP SH-SY5Y ENCSR000EXZ.GATA3.SH-SY5Y 326 bp overlap

ChIP T-47D GSE51274.GATA3.T-47D 242 bp overlap

ChIP thymocyte GSE71751.GATA3.thymocyte 218 bp overlap

GATA3_Nter 2 datasets

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 343 bp overlap

ChIP T-47D_flp-ctrl GSE99479.GATA3_Nter.T-47D_flp-ctrl 173 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 687 bp overlap

ChIP DE DE-GATA4-2 723 bp overlap

ChIP foregut GSE117136.GATA4.foregut 359 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 569 bp overlap

ChIP DE DE-GATA6-2 630 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 446 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 696 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 425 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 613 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 723 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 575 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 702 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 518 bp overlap

GLIS2 1 dataset

Motif DE_36h DE_36h-GLIS2_MA0736.1 14 bp overlap

HAND2 3 datasets

ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 356 bp overlap

ChIP Kelly GSE94822.HAND2.Kelly 220 bp overlap

ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 279 bp overlap

HDAC2 2 datasets

ChIP RH4_DMSO-6H GSE116344.HDAC2.RH4_DMSO-6H 350 bp overlap

ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 261 bp overlap

HDAC3 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 339 bp overlap

ChIP HCT-116_KOFBXW7 GSE57398.HSF1.HCT-116_KOFBXW7 191 bp overlap

ChIP K-562_EPZ GSE129380.IRF1.K-562_EPZ 122 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 444 bp overlap

KDM1A 2 datasets

ChIP K-562_Wnt GSE117944.KDM1A.K-562_Wnt 77 bp overlap

ChIP SH-SY5Y_B3 GSE58258.KDM1A.SH-SY5Y_B3 198 bp overlap

ChIP RH4 GSE155861.MTA2.RH4 229 bp overlap

ChIP SK-N-SH ENCSR000EIA.MXI1.SK-N-SH 146 bp overlap

MYCN 2 datasets

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 282 bp overlap

ChIP RH4 GSE83726.MYCN.RH4 265 bp overlap

MYOD1 1 dataset

ChIP RH4 GSE83726.MYOD1.RH4 455 bp overlap

Mecom 1 dataset

Motif DE_36h DE_36h-Mecom_MA0029.2 11 bp overlap

NELFE 1 dataset

ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 162 bp overlap

NEUROG2 4 datasets

ChIP MRC-5_NFD_02DPT GSE75910.NEUROG2.MRC-5_NFD_02DPT 236 bp overlap

ChIP MRC-5_NFD_1DPT GSE75910.NEUROG2.MRC-5_NFD_1DPT 258 bp overlap

ChIP MRC-5_N_02DPT GSE75910.NEUROG2.MRC-5_N_02DPT 225 bp overlap

ChIP MRC-5_N_1DPT GSE75910.NEUROG2.MRC-5_N_1DPT 184 bp overlap

NRIP1 1 dataset

ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 156 bp overlap

PAX3-FOXO1 3 datasets

ChIP Hs-352-Sk GSE83725.PAX3-FOXO1.Hs-352-Sk 214 bp overlap

ChIP RH3 GSE83726.PAX3-FOXO1.RH3 396 bp overlap

ChIP RH4 GSE140115.PAX3-FOXO1.RH4 393 bp overlap

PHOX2B 2 datasets

ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 400 bp overlap

ChIP SK-N-BE2-C GSE94822.PHOX2B.SK-N-BE2-C 164 bp overlap

PITX3 1 dataset

ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 382 bp overlap

PLAG1 1 dataset

ChIP K-562 GSE111469.PLAG1.K-562 204 bp overlap

PLAGL2 1 dataset

Motif DE_36h DE_36h-PLAGL2_MA1548.2 8 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 173 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 226 bp overlap

RAD21 3 datasets

ChIP RH4 GSE83726.RAD21.RH4 469 bp overlap

ChIP SK-N-SH ENCFF747MAS 251 bp overlap

ChIP SK-N-SH ENCSR000EHX.RAD21.SK-N-SH 170 bp overlap

RARA 2 datasets

ChIP hiPSC_D3 GSE109172.RARA.hiPSC_D3 194 bp overlap

ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 294 bp overlap

RCOR1 3 datasets

ChIP K562 ENCFF216EEJ 215 bp overlap

ChIP SK-N-SH ENCFF518EXB 314 bp overlap

ChIP SK-N-SH ENCSR009TKN.RCOR1.SK-N-SH 179 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 638 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 653 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 314 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 309 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 694 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 576 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 217 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 510 bp overlap

Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap

ChIP DC_96h_donorM GSE128834.SPI1.DC_96h_donorM 166 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 265 bp overlap

TAL1 5 datasets

ChIP K-562 GSE107726.TAL1.K-562 223 bp overlap

ChIP K-562 ENCSR000EHB.TAL1.K-562 114 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 188 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 193 bp overlap

ChIP K562 ENCFF661CCK 210 bp overlap

TCF12 2 datasets

ChIP K-562 ENCSR744WOO.TCF12.K-562 168 bp overlap

ChIP K562 ENCFF931DJY 298 bp overlap

TCF3 2 datasets

ChIP K-562 ENCSR970OJY.TCF3.K-562 150 bp overlap

ChIP K562 ENCFF319QZT 249 bp overlap

ChIP SH-SY5Y GSE96915.TCF4.SH-SY5Y 201 bp overlap

TFAP2B 1 dataset

ChIP SK-N-SH ENCFF869XXQ 204 bp overlap

TWIST1 2 datasets

ChIP BE2C GSE80151.TWIST1.BE2C 290 bp overlap

ChIP SK-N-BE2-C GSE80151.TWIST1.SK-N-BE2-C 290 bp overlap

Tfcp2l1 1 dataset

Motif DE_36h DE_36h-Tfcp2l1_MA0145.2 14 bp overlap

VEZF1 1 dataset

Motif DE_36h DE_36h-VEZF1_MA1578.2 6 bp overlap

ChIP RH4_DMSO-6H GSE116344.YY1.RH4_DMSO-6H 232 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 175 bp overlap

ZFP14 1 dataset

Motif DE_36h DE_36h-ZFP14_MA1972.1 15 bp overlap

ZFP36 1 dataset

ChIP K-562 ENCSR776CYN.ZFP36.K-562 178 bp overlap

ZFP64 1 dataset

ChIP HEK293 GSE76494.ZFP64.HEK293 116 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 701 bp overlap

Motif DE_36h DE_36h-ZIC1_MA0696.1 14 bp overlap

Motif DE_36h DE_36h-ZIC4_MA0751.2 14 bp overlap

Motif DE_36h DE_36h-ZIC5_MA1584.2 15 bp overlap

ZNF16 1 dataset

Motif DE_36h DE_36h-ZNF16_MA1654.2 21 bp overlap

ZNF213 1 dataset

Motif DE_36h DE_36h-ZNF213_MA2121.1 12 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 244 bp overlap

ZNF384 2 datasets

ChIP K-562 ENCSR000EFP.ZNF384.K-562 108 bp overlap

ChIP K562 ENCFF365NXQ 183 bp overlap

ZNF460 1 dataset

Motif DE_36h DE_36h-ZNF460_MA1596.1 16 bp overlap

ZNF711 1 dataset

ChIP HEK293T GSE145160.ZNF711.HEK293T 429 bp overlap