chr19:12,664,457–12,664,721

chr19 : 12,664,457 – 12,664,721

264 bp 64 TFs 5 linked genes

This 264 bp open chromatin element is linked to 5 target genes and is bound by 64 transcription factors.

Linked Genes

5 genes

Gene	Expression	Dist. to TSS	Distance	Link type
MAN2B1		2.0 kb	Proximal	Proximity
WDR83		2.1 kb	Proximal	Proximity
ENSG00000269590		4.7 kb	Proximal	Proximity
WDR83OS		4.7 kb	Proximal	Proximity
ENSG00000285583		6.3 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

64 transcription factors

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 135 bp overlap

ARID4B 1 dataset

ChIP PC-3 GSE116669.ARID4B.PC-3 244 bp overlap

BCL11A 9 datasets

ChIP CD34_Day3_30min GSE104676.BCL11A.CD34_Day3_30min 63 bp overlap

ChIP CD34_Day5_30min GSE104676.BCL11A.CD34_Day5_30min 196 bp overlap

ChIP CD34_Day7_30min GSE104676.BCL11A.CD34_Day7_30min 100 bp overlap

ChIP CD34_Day9_30min GSE104676.BCL11A.CD34_Day9_30min 183 bp overlap

ChIP CD34_Day9_60min GSE104676.BCL11A.CD34_Day9_60min 101 bp overlap

ChIP CD34_Day9_90min GSE104676.BCL11A.CD34_Day9_90min 119 bp overlap

ChIP HUDEP-2_30min GSE104676.BCL11A.HUDEP-2_30min 155 bp overlap

ChIP HUDEP-2_90min GSE104676.BCL11A.HUDEP-2_90min 182 bp overlap

ChIP HUDEP-2_BCL11A-ER-V5 GSE103445.BCL11A.HUDEP-2_BCL11A-ER-V5 200 bp overlap

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 53 bp overlap

ChIP K-562 ENCSR808AKZ.BCOR.K-562 226 bp overlap

BRD4 7 datasets

ChIP CLL_patient1_4h_CpG GSE109411.BRD4.CLL_patient1_4h_CpG 264 bp overlap

ChIP CLL_patient2_4h_CpG GSE109411.BRD4.CLL_patient2_4h_CpG 180 bp overlap

ChIP CLL_patient2_4h_CpG_BET GSE109411.BRD4.CLL_patient2_4h_CpG_BET 195 bp overlap

ChIP CLL_patient4_4h_CpG_BET GSE109411.BRD4.CLL_patient4_4h_CpG_BET 134 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 86 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 235 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 209 bp overlap

CBFA2T2 1 dataset

ChIP NCCIT GSE71675.CBFA2T2.NCCIT 51 bp overlap

ChIP T-47D GSE62428.CHD8.T-47D 167 bp overlap

ChIP K-562 ENCSR731LHZ.E4F1.K-562 260 bp overlap

EGR1 2 datasets

ChIP A-375 GSE116190.EGR1.A-375 112 bp overlap

ChIP GM12878 ENCFF092DJY 84 bp overlap

EP300 1 dataset

ChIP WA01 ENCSR000BKK.EP300.WA01 166 bp overlap

ESR1 11 datasets

ChIP Ishikawa_DMSO GSE132426.ESR1.Ishikawa_DMSO 264 bp overlap

ChIP Ishikawa_E2 GSE132426.ESR1.Ishikawa_E2 204 bp overlap

ChIP Ishikawa_ETV4-OE GSE129803.ESR1.Ishikawa_ETV4-OE 234 bp overlap

ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 163 bp overlap

ChIP MCF-7_IL1b_45m GSE67295.ESR1.MCF-7_IL1b_45m 161 bp overlap

ChIP MCF-7_jc5855 GSE126004.ESR1.MCF-7_jc5855 203 bp overlap

ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 172 bp overlap

ChIP T-47D_D538G_E2 GSE148277.ESR1.T-47D_D538G_E2 252 bp overlap

ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 264 bp overlap

ChIP T-47D_Y537S_E2 GSE148277.ESR1.T-47D_Y537S_E2 264 bp overlap

ChIP breast_tumor_Male_21 GSE104399.ESR1.breast_tumor_Male_21 264 bp overlap

ChIP RH30_DMSO GSE85169.EZH2.RH30_DMSO 264 bp overlap

GATA1 2 datasets

ChIP CD34_Day9_30min GSE104676.GATA1.CD34_Day9_30min 151 bp overlap

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 157 bp overlap

ChIP K-562 ENCSR197ALX.HDGF.K-562 264 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 209 bp overlap

HNF4A 1 dataset

ChIP IM95 GSE114018.HNF4A.IM95 121 bp overlap

HNRNPL 1 dataset

ChIP Hep-G2 GSE120104.HNRNPL.Hep-G2 123 bp overlap

ChIP H1 ENCFF621PNP 241 bp overlap

ChIP MDA-MB-231 GSE112444.JUN.MDA-MB-231 127 bp overlap

ChIP WA01 ENCSR000ECA.JUN.WA01 174 bp overlap

KDM5B 1 dataset

ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 155 bp overlap

ChIP HEK293 ENCSR859BMR.KLF1.HEK293 170 bp overlap

KLF16 2 datasets

ChIP K-562 ENCSR760UVO.KLF16.K-562 216 bp overlap

ChIP K562 ENCFF464PIV 95 bp overlap

KLF17 1 dataset

ChIP HEK293 ENCSR065WUF.KLF17.HEK293 135 bp overlap

ChIP Hep-G2 ENCSR108MKR.MNX1.Hep-G2 151 bp overlap

ChIP Hep-G2 ENCSR983KRB.MTA1.Hep-G2 70 bp overlap

ChIP K-562 ENCSR180NCY.MTA3.K-562 264 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 247 bp overlap

NELFE 1 dataset

ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 250 bp overlap

ChIP HEK293 GSE89017.OGG1.HEK293 166 bp overlap

PCBP1 1 dataset

ChIP Hep-G2 GSE120104.PCBP1.Hep-G2 134 bp overlap

POLR2A 2 datasets

ChIP GM12892 ENCFF245LYF 264 bp overlap

ChIP H1 ENCFF833NJP 264 bp overlap

POLR2G 2 datasets

ChIP K562 ENCFF047BLG 264 bp overlap

ChIP K562 ENCFF648YPL 264 bp overlap

POU5F1 1 dataset

ChIP BG03 GSE21614.POU5F1.BG03 208 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 264 bp overlap

RAD21 1 dataset

ChIP HCT-116 GSE131606.RAD21.HCT-116 213 bp overlap

RBFOX2 2 datasets

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 264 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 126 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 264 bp overlap

REST 4 datasets

ChIP K-562 ENCSR137ZMQ.REST.K-562 264 bp overlap

ChIP K-562 ENCSR000BMW.REST.K-562 110 bp overlap

ChIP K562 ENCFF688UKW 264 bp overlap

ChIP hiPSC_IA12 GSE106870.REST.hiPSC_IA12 253 bp overlap

SCRT1 1 dataset

ChIP HEK293 ENCSR605MGM.SCRT1.HEK293 141 bp overlap

SIN3A 1 dataset

ChIP WA01 ENCSR000EBO.SIN3A.WA01 194 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 176 bp overlap

ChIP HEK293T_WT GSE122299.SMC3.HEK293T_WT 196 bp overlap

ChIP Hep-G2 ENCSR460YAM.SP1.Hep-G2 264 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 264 bp overlap

ChIP HEK293 ENCFF181QXT 244 bp overlap

ChIP HEK293 ENCSR807LQP.SP2.HEK293 264 bp overlap

ChIP H1 ENCFF473YOB 264 bp overlap

ChIP HEK293 GSE76494.SP4.HEK293 264 bp overlap

ChIP WA01 ENCSR000BQV.SP4.WA01 214 bp overlap

SREBP2 1 dataset

ChIP monocyte GSE129202.SREBP2.monocyte 246 bp overlap

SRSF3 2 datasets

ChIP K-562 GSE120104.SRSF3.K-562 253 bp overlap

ChIP K-562 ENCSR268QIQ.SRSF3.K-562 148 bp overlap

STAT3 2 datasets

ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 178 bp overlap

ChIP TMD8 GSE106844.STAT3.TMD8 169 bp overlap

TAF1 2 datasets

ChIP Hep-G2 ENCSR918OKK.TAF1.Hep-G2 114 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 177 bp overlap

ChIP K-562 ENCSR000BNM.TAF7.K-562 130 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 158 bp overlap

ChIP hESC GSE122298.TBP.hESC 254 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 156 bp overlap

TFCP2 1 dataset

ChIP K562 ENCFF984WXL 264 bp overlap

TRIM24 1 dataset

ChIP K-562 ENCSR907MZR.TRIM24.K-562 224 bp overlap

TRIM28 1 dataset

ChIP HCT-116 GSE72622.TRIM28.HCT-116 195 bp overlap

ChIP K-562 ENCSR000BKU.YY1.K-562 159 bp overlap

ZBTB7A 1 dataset

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 91 bp overlap

ZBTB8A 2 datasets

ChIP HEK293 ENCFF303WRD 244 bp overlap

ChIP HEK293 ENCSR481FEC.ZBTB8A.HEK293 119 bp overlap

ChIP HEK293T_22Rv1 GSE145160.ZFX.HEK293T_22Rv1 237 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 230 bp overlap

ChIP HepG2 ENCFF016NZF 264 bp overlap

ZNF184 2 datasets

ChIP K-562 ENCSR621ATC.ZNF184.K-562 264 bp overlap

ChIP K562 ENCFF717TPQ 264 bp overlap

ZNF274 1 dataset

ChIP Hep-G2 ENCSR871VNN.ZNF274.Hep-G2 179 bp overlap

ChIP K-562 ENCSR195QFV.ZNF3.K-562 188 bp overlap

ZNF335 3 datasets

ChIP HEK293 ENCFF784SLD 193 bp overlap

ChIP HEK293 ENCFF784SLD 264 bp overlap

ChIP HEK293 ENCSR328SUD.ZNF335.HEK293 264 bp overlap

ZNF765 1 dataset

ChIP HEK293T GSE78099.ZNF765.HEK293T 225 bp overlap

ZNF891 1 dataset

ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 246 bp overlap