chr17:75,481,081–75,481,680

chr17 : 75,481,081 – 75,481,680

599 bp 64 TFs 14 linked genes

This 599 bp open chromatin element is linked to 14 target genes and is bound by 64 transcription factors.

Linked Genes

14 genes

Gene	Expression	Dist. to TSS	Distance	Link type
TMEM94		24.7 kb	Distal	Multiome
TSEN54		35.2 kb	Distal	Multiome
LLGL2		44.3 kb	Distal	Multiome
GRB2		75.7 kb	Distal	Multiome
MYO15B		106.7 kb	Distal	Multiome
RECQL5		185.8 kb	Distal	Multiome
SAP30BP		186.0 kb	Distal	Multiome
MIF4GD		210.2 kb	Distal	Multiome
MRPS7		219.5 kb	Distal	Multiome
GGA3		219.8 kb	Distal	Multiome
NUP85		275.7 kb	Distal	Multiome
GALK1		283.8 kb	Distal	Multiome
SUMO2		298.4 kb	Distal	Multiome
H3-3B		298.4 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

64 transcription factors

ChIP LNCaP_SHGATA2_R1881 GSE69043.AR.LNCaP_SHGATA2_R1881 107 bp overlap

ChIP MCF-7 GSE48930.AR.MCF-7 275 bp overlap

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 241 bp overlap

BRD1 2 datasets

ChIP HUES-64 GSE104059.BRD1.HUES-64 219 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 136 bp overlap

BRD2 5 datasets

ChIP THP-1_DMSO GSE138084.BRD2.THP-1_DMSO 169 bp overlap

ChIP THP-1_iBET GSE138084.BRD2.THP-1_iBET 474 bp overlap

ChIP THP-1_iBET-BD1 GSE138084.BRD2.THP-1_iBET-BD1 485 bp overlap

ChIP THP-1_iBET-BD2 GSE138084.BRD2.THP-1_iBET-BD2 126 bp overlap

ChIP THP-1_iBET-BD2 GSE138084.BRD2.THP-1_iBET-BD2 290 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD3.K-562_DMSO-IFNG 201 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 111 bp overlap

ChIP retina_Hu20 GSE137311.CRX.retina_Hu20 327 bp overlap

ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 466 bp overlap

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 463 bp overlap

CTCF 7 datasets

ChIP D721Med ENCFF513FYD 211 bp overlap

ChIP GP5D_SIRAD21 GSE51234.CTCF.GP5D_SIRAD21 265 bp overlap

ChIP WERI-Rb-1 ENCFF349QKF 152 bp overlap

ChIP leukemia_CEBPA-24h GSE142161.CTCF.leukemia_CEBPA-24h 230 bp overlap

ChIP retina_Hu22 GSE137311.CTCF.retina_Hu22 383 bp overlap

ChIP retina_Hu25 GSE137311.CTCF.retina_Hu25 399 bp overlap

ChIP retina_Hu6 GSE137311.CTCF.retina_Hu6 588 bp overlap

Cebpa 3 datasets

ChIP BLaER1 ENCFF031ISE 171 bp overlap

ChIP BLaER1 ENCFF274GAT 180 bp overlap

ChIP BLaER1 ENCFF460KDD 251 bp overlap

DNMT3B 2 datasets

ChIP HUES-8 GSE99346.DNMT3B.HUES-8 291 bp overlap

ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 254 bp overlap

ChIP GM12878 ENCSR439WAF.E4F1.GM12878 76 bp overlap

ChIP MCF-7 ENCFF679ZBN 341 bp overlap

ChIP HEK293 ENCFF336LFH 303 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 271 bp overlap

ChIP SEM GSE117864.ERG.SEM 85 bp overlap

ChIP TSU-1621MT_ATRA GSE60477.ERG.TSU-1621MT_ATRA 101 bp overlap

ESR1 6 datasets

ChIP Ishikawa_DMSO GSE132426.ESR1.Ishikawa_DMSO 244 bp overlap

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 599 bp overlap

ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 218 bp overlap

ChIP MCF-7_PaPE-1 GSE93510.ESR1.MCF-7_PaPE-1 524 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 391 bp overlap

ChIP MCF-7_Veh GSE93510.ESR1.MCF-7_Veh 114 bp overlap

ChIP CTV-1_DSG GSE128835.ETS1.CTV-1_DSG 111 bp overlap

EZH2_phosphoT487 1 dataset

ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 272 bp overlap

FOXA1 2 datasets

ChIP MCF-7_DOX-neg GSE124654.FOXA1.MCF-7_DOX-neg 193 bp overlap

ChIP T-47D_CR3flp GSE99479.FOXA1.T-47D_CR3flp 189 bp overlap

FOXA2 3 datasets

ChIP Caco-2 GSE66218.FOXA2.Caco-2 119 bp overlap

ChIP DE DE-FOXA2-1 505 bp overlap

ChIP DE DE-FOXA2-2 527 bp overlap

GATA3_Nter 1 dataset

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 169 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 591 bp overlap

ChIP DE DE-GATA4-2 598 bp overlap

ChIP foregut GSE117136.GATA4.foregut 477 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 448 bp overlap

GATA6 11 datasets

ChIP DE DE-GATA6-1 538 bp overlap

ChIP DE DE-GATA6-2 599 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 421 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 438 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 491 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 456 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 538 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 518 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 516 bp overlap

ChIP foregut GSE117136.GATA6.foregut 463 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 284 bp overlap

GLIS1 2 datasets

ChIP HEK293 ENCFF299RSE 426 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 599 bp overlap

GLIS2 1 dataset

ChIP HEK293 ENCSR535DIA.GLIS2.HEK293 351 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 274 bp overlap

HDAC3 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 318 bp overlap

HNF4A 1 dataset

ChIP GP5D GSE51234.HNF4A.GP5D 387 bp overlap

ChIP HCT-116_KOFBXW7 GSE57398.HSF1.HCT-116_KOFBXW7 187 bp overlap

JMJD1C 1 dataset

ChIP Kasumi-1 GSE63484.JMJD1C.Kasumi-1 127 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 364 bp overlap

ChIP MDA-MB-231 GSE112444.JUN.MDA-MB-231 89 bp overlap

KMT2A 1 dataset

ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 240 bp overlap

ChIP CCRF-CEM GSE33850.LMO2.CCRF-CEM 112 bp overlap

MED1 6 datasets

ChIP HCT-116 GSE121798.MED1.HCT-116 383 bp overlap

ChIP HCT-116_shLuc GSE121798.MED1.HCT-116_shLuc 599 bp overlap

ChIP HCT-116_thaps GSE121798.MED1.HCT-116_thaps 264 bp overlap

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 161 bp overlap

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 287 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 61 bp overlap

MEF2D 3 datasets

ChIP retina_Hu13 GSE137311.MEF2D.retina_Hu13 393 bp overlap

ChIP retina_Hu21 GSE137311.MEF2D.retina_Hu21 467 bp overlap

ChIP retina_Hu25 GSE137311.MEF2D.retina_Hu25 390 bp overlap

ChIP GP5D GSE51234.MYC.GP5D 318 bp overlap

NELFE 1 dataset

ChIP K-562_HS GSE112379.NELFE.K-562_HS 66 bp overlap

NEUROD1 4 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 531 bp overlap

ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 253 bp overlap

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 243 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 337 bp overlap

NFKB1 1 dataset

ChIP HEK293T_2KR GSE129618.NFKB1.HEK293T_2KR 213 bp overlap

NIPBL 1 dataset

ChIP GP5D GSE51234.NIPBL.GP5D 88 bp overlap

NR2F2 2 datasets

ChIP liver ENCSR338MMB.NR2F2.liver 175 bp overlap

ChIP liver ENCSR168SMX.NR2F2.liver 153 bp overlap

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 492 bp overlap

ChIP MCF-7_PROG GSE68355.PGR.MCF-7_PROG 236 bp overlap

POLR2A 1 dataset

ChIP MCF-7 ENCFF411WCU 313 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 50 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 356 bp overlap

ChIP retina_Hu22 GSE137311.RORB.retina_Hu22 432 bp overlap

RUNX1 1 dataset

ChIP Jurkat GSE85524.RUNX1.Jurkat 246 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 574 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 420 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 407 bp overlap

SMARCA4 1 dataset

ChIP CTV-1_FLAG GSE128835.SMARCA4.CTV-1_FLAG 99 bp overlap

ChIP GP5D GSE51234.SMC3.GP5D 134 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 282 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 409 bp overlap

SPI1 7 datasets

ChIP CD34_FETAL GSE70660.SPI1.CD34_FETAL 133 bp overlap

ChIP DC_96h_donorM GSE128834.SPI1.DC_96h_donorM 161 bp overlap

ChIP K-562 GSE70482.SPI1.K-562 156 bp overlap

ChIP Kasumi-1_SICTR GSE60130.SPI1.Kasumi-1_SICTR 127 bp overlap

ChIP THP-1 GSE128834.SPI1.THP-1 77 bp overlap

ChIP THP-1_DIFF GSE25426.SPI1.THP-1_DIFF 104 bp overlap

ChIP primary-monocyte_18h_donorO GSE128834.SPI1.primary-monocyte_18h_donorO 65 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 239 bp overlap

TAF15 1 dataset

ChIP Hep-G2 GSE120104.TAF15.Hep-G2 99 bp overlap

TBL1X 1 dataset

ChIP HEK293T GSE35197.TBL1X.HEK293T 175 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 71 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 133 bp overlap

TRIM28 1 dataset

ChIP AF22 GSE84259.TRIM28.AF22 54 bp overlap

XRCC5 1 dataset

ChIP K-562 GSE120104.XRCC5.K-562 220 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 290 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 426 bp overlap

ZIC2 2 datasets

ChIP HEK293 ENCFF033NQQ 411 bp overlap

ChIP HEK293 ENCFF033NQQ 233 bp overlap

ZNF770 1 dataset

ChIP HEK293 GSE76494.ZNF770.HEK293 180 bp overlap