chr17:47,310,107–47,310,844

chr17 : 47,310,107 – 47,310,844

737 bp 92 TFs 6 linked genes

This 737 bp open chromatin element is linked to 6 target genes and is bound by 92 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
EFCAB13		13.5 kb	Distal	Multiome
ENSG00000253347		113.1 kb	Distal	Multiome
CDC27		121.2 kb	Distal	Multiome
MRPL45P2		182.0 kb	Distal	Multiome
ENSG00000262879		210.2 kb	Distal	Multiome
NPEPPS		220.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

92 transcription factors

ChIP LNCaP GSE43720.AR.LNCaP 136 bp overlap

ChIP MDA-MB-453_FOXA1 ERP003503.AR.MDA-MB-453_FOXA1 140 bp overlap

ARID1B 1 dataset

ChIP K-562 ENCSR822CCM.ARID1B.K-562 211 bp overlap

ARNTL 1 dataset

ChIP U2OS GSE44236.ARNTL.U2OS 212 bp overlap

ASCL1 3 datasets

Motif DE_72h DE_72h-ASCL1_MA1631.2 9 bp overlap

ChIP NCI-H2107 GSE69394.ASCL1.NCI-H2107 135 bp overlap

ChIP SCLC_ASCLP GSE61197.ASCL1.SCLC_ASCLP 157 bp overlap

Ascl2 1 dataset

Motif DE_72h DE_72h-Ascl2_MA0816.1 10 bp overlap

ChIP K-562 ENCSR808AKZ.BCOR.K-562 224 bp overlap

BRD4 2 datasets

ChIP HEK293_Ctrl GSE129407.BRD4.HEK293_Ctrl 194 bp overlap

ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 418 bp overlap

CREB1 1 dataset

ChIP MCF-7 ENCSR620DUQ.CREB1.MCF-7 251 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF262VBH 313 bp overlap

ChIP NTERA2 GSE58641.DDX5.NTERA2 298 bp overlap

E4F1 2 datasets

ChIP MCF-7 ENCFF679UFD 331 bp overlap

ChIP MCF-7 ENCSR841YWU.E4F1.MCF-7 272 bp overlap

ChIP ProEs GSE59087.EED.ProEs 142 bp overlap

ChIP HEK293 ENCFF336LFH 291 bp overlap

EHMT2 1 dataset

ChIP K-562 ENCSR175EOM.EHMT2.K-562 191 bp overlap

Motif DE_72h DE_72h-ELF3_MA0640.3 9 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 411 bp overlap

EP300 1 dataset

ChIP Ishikawa ENCSR000BUE.EP300.Ishikawa 215 bp overlap

ERF::FOXI1 1 dataset

Motif DE_72h DE_72h-ERFFOXI1_MA1935.2 10 bp overlap

ERF::FOXO1 1 dataset

Motif DE_72h DE_72h-ERFFOXO1_MA1936.2 12 bp overlap

ESR1 2 datasets

ChIP MDA-MB-134-VI_ESTROGEN GSE51022.ESR1.MDA-MB-134-VI_ESTROGEN 237 bp overlap

ChIP breast_mrnahist ERP002305.ESR1.breast_mrnahist 157 bp overlap

Motif DE_72h DE_72h-ETV1_MA0761.3 9 bp overlap

ETV2::FOXI1 1 dataset

Motif DE_72h DE_72h-ETV2FOXI1_MA1942.2 11 bp overlap

ETV5::FOXI1 1 dataset

Motif DE_72h DE_72h-ETV5FOXI1_MA1946.2 12 bp overlap

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 90 bp overlap

FIGLA 1 dataset

Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap

FLI1 2 datasets

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 298 bp overlap

ChIP A-673_2_KRAB_eSOX2_1 GSE106914.FLI1.A-673_2_KRAB_eSOX2_1 168 bp overlap

FLI1::FOXI1 1 dataset

Motif DE_72h DE_72h-FLI1FOXI1_MA1950.2 11 bp overlap

FOXA1 1 dataset

ChIP T-47D_CR3flp GSE99479.FOXA1.T-47D_CR3flp 183 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 511 bp overlap

ChIP DE DE-FOXA2-2 527 bp overlap

ChIP liver_CARN1618 ERP008682.FOXA2.liver_CARN1618 176 bp overlap

FOXJ2::ELF1 1 dataset

Motif DE_72h DE_72h-FOXJ2ELF1_MA1952.2 11 bp overlap

FOXO1::ELF1 1 dataset

Motif DE_72h DE_72h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXO1::ELK1 1 dataset

Motif DE_72h DE_72h-FOXO1ELK1_MA1954.2 13 bp overlap

FOXO1::ELK3 1 dataset

Motif DE_72h DE_72h-FOXO1ELK3_MA1955.2 13 bp overlap

GATA2 1 dataset

ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 191 bp overlap

GATA3 2 datasets

ChIP MCF-7 ENCFF352QVM 369 bp overlap

ChIP T-47D GSE51274.GATA3.T-47D 305 bp overlap

GATA3_Nter 1 dataset

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 325 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 527 bp overlap

ChIP DE DE-GATA4-2 642 bp overlap

GATA6 10 datasets

ChIP AGS GSE51936.GATA6.AGS 81 bp overlap

ChIP DE DE-GATA6-1 538 bp overlap

ChIP DE DE-GATA6-2 701 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 564 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 579 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 552 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 569 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 574 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 570 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 587 bp overlap

GLIS1 2 datasets

ChIP HEK293 ENCFF299RSE 251 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 329 bp overlap

HDAC2 1 dataset

ChIP K-562 ENCSR893WSB.HDAC2.K-562 324 bp overlap

ChIP K-562 ENCSR563YDA.HDGF.K-562 282 bp overlap

HNF4G 1 dataset

ChIP Hep-G2 ENCSR000BNJ.HNF4G.Hep-G2 156 bp overlap

HNRNPH1 2 datasets

ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 152 bp overlap

ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 146 bp overlap

HOXB4 1 dataset

Motif DE_72h DE_72h-HOXB4_MA1499.2 6 bp overlap

HOXC4 1 dataset

Motif DE_72h DE_72h-HOXC4_MA1504.2 6 bp overlap

HOXD4 1 dataset

Motif DE_72h DE_72h-HOXD4_MA1507.2 6 bp overlap

IKZF1 1 dataset

Motif DE_72h DE_72h-IKZF1_MA1508.2 8 bp overlap

IKZF2 1 dataset

Motif DE_72h DE_72h-IKZF2_MA2326.1 6 bp overlap

Ikzf3 1 dataset

Motif DE_72h DE_72h-Ikzf3_MA1992.2 9 bp overlap

Motif DE_72h DE_72h-JUN_MA0488.2 10 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 349 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 333 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 486 bp overlap

MED1 4 datasets

ChIP HCT-116 GSE121798.MED1.HCT-116 227 bp overlap

ChIP HCT-116_shLuc GSE121798.MED1.HCT-116_shLuc 267 bp overlap

ChIP HCT-116_shLuc_thaps GSE121798.MED1.HCT-116_shLuc_thaps 217 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 649 bp overlap

Motif DE_72h DE_72h-MSC_MA0665.1 10 bp overlap

ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 305 bp overlap

Motif DE_72h DE_72h-MYF6_MA0667.1 10 bp overlap

MYOD1 1 dataset

ChIP rhabdomyosarcoma GSE50413.MYOD1.rhabdomyosarcoma 109 bp overlap

NANOG 2 datasets

ChIP WA01 ERP004238.NANOG.WA01 320 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 455 bp overlap

NCAPH2 2 datasets

ChIP RMG-I GSE120058.NCAPH2.RMG-I 177 bp overlap

ChIP RMG-I GSE120058.NCAPH2.RMG-I 391 bp overlap

PPARG 1 dataset

ChIP HUVEC-C_DMSO_HYPO GSE50144.PPARG.HUVEC-C_DMSO_HYPO 147 bp overlap

Ptf1A 1 dataset

Motif DE_72h DE_72h-Ptf1A_MA1620.2 8 bp overlap

RUNX2 1 dataset

ChIP LNCaP-C4-2B GSE33889.RUNX2.LNCaP-C4-2B 493 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 585 bp overlap

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 55 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 290 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 397 bp overlap

SMAD3 2 datasets

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 181 bp overlap

ChIP endoderm GSE29422.SMAD3.endoderm 189 bp overlap

SMARCA4 2 datasets

ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4 498 bp overlap

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 355 bp overlap

SMARCA5 1 dataset

ChIP K-562 ENCSR895HSJ.SMARCA5.K-562 244 bp overlap

SMARCE1 1 dataset

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 245 bp overlap

ChIP monocyte_IFNg-LPS GSE120943.SMC1.monocyte_IFNg-LPS 122 bp overlap

SNAI1 1 dataset

Motif DE_72h DE_72h-SNAI1_MA1558.2 7 bp overlap

SNAI3 1 dataset

Motif DE_72h DE_72h-SNAI3_MA1559.2 9 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 559 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 594 bp overlap

ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SS18.BIN-67_lentivirus-SMARCA4 250 bp overlap

SUZ12 1 dataset

ChIP MCF-7 ENCSR757EMK.SUZ12.MCF-7 211 bp overlap

Stat5b 1 dataset

Motif DE_72h DE_72h-Stat5b_MA1625.2 9 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap

ChIP K-562 GSE55306.TBP.K-562 202 bp overlap

TCF12 2 datasets

Motif DE_72h DE_72h-TCF12_MA1648.2 7 bp overlap

ChIP Ishikawa ENCSR000BUV.TCF12.Ishikawa 174 bp overlap

TCF3 2 datasets

Motif DE_72h DE_72h-TCF3_MA0522.4 7 bp overlap

ChIP NPC GSE154479.TCF3.NPC 224 bp overlap

Motif DE_72h DE_72h-TCF4_MA0830.3 8 bp overlap

TFAP2B 1 dataset

ChIP SK-N-SH ENCFF869XXQ 441 bp overlap

ZBTB1 1 dataset

ChIP MCF-7 ENCSR309ELI.ZBTB1.MCF-7 251 bp overlap

Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 365 bp overlap

ChIP HEK293 ENCFF033NQQ 244 bp overlap

Motif DE_72h DE_72h-ZIC4_MA0751.2 14 bp overlap

ZKSCAN1 1 dataset

ChIP MCF-7 ENCSR449UFF.ZKSCAN1.MCF-7 232 bp overlap

ZNF143 3 datasets

Motif DE_72h DE_72h-ZNF143_MA0088.2 16 bp overlap

ChIP MCF-7 GSE76454.ZNF143.MCF-7 190 bp overlap

ChIP MCF-7_E2 GSE76454.ZNF143.MCF-7_E2 258 bp overlap

ZNF175 1 dataset

Motif DE_72h DE_72h-ZNF175_MA2332.1 9 bp overlap

ZNF410 1 dataset

ChIP K-562 GSE97661.ZNF410.K-562 131 bp overlap

ZNF449 1 dataset

ChIP HEK293 GSE76494.ZNF449.HEK293 123 bp overlap

ZNF680 1 dataset

Motif DE_72h DE_72h-ZNF680_MA1729.2 11 bp overlap

ZNF76 1 dataset

Motif DE_72h DE_72h-ZNF76_MA1716.2 17 bp overlap