chr1 : 240,609,583 – 240,610,957
1,374 bp 78 TFs 1 linked gene
This 1.4 kb open chromatin element is linked to GREM2 and is bound by 78 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
GREM2 1.2 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr1:240,604,583 – 240,615,957
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
78 transcription factors
Source
Cell type
AR 5 datasets
ChIP LNCaP GSE80256.AR.LNCaP 225 bp overlap
ChIP LNCaP_1F5 GSE30623.AR.LNCaP_1F5 169 bp overlap
ChIP LNCaP_1F5_SIFOXA1 GSE30623.AR.LNCaP_1F5_SIFOXA1 192 bp overlap
ChIP VCaP_DHT24H_SHFOXP1 GSE58428.AR.VCaP_DHT24H_SHFOXP1 308 bp overlap
ChIP VCaP_R1881 GSE32892.AR.VCaP_R1881 118 bp overlap
ARID1A 1 dataset
ChIP HAP1 GSE108387.ARID1A.HAP1 548 bp overlap
BAF155 1 dataset
ChIP VCaP_shARID1A GSE110655.BAF155.VCaP_shARID1A 160 bp overlap
BRCA1 1 dataset
ChIP K-562 ENCSR223MLH.BRCA1.K-562 531 bp overlap
BRD4 4 datasets
ChIP HAP1 GSE108387.BRD4.HAP1 361 bp overlap
ChIP HAP1 GSE108387.BRD4.HAP1 496 bp overlap
ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 216 bp overlap
ChIP T-47D_DMSO GSE63581.BRD4.T-47D_DMSO 243 bp overlap
CASZ1 1 dataset
ChIP rhabdomyosarcoma_DOX GSE126142.CASZ1.rhabdomyosarcoma_DOX 203 bp overlap
CBX4 1 dataset
ChIP HEK293T GSE53495.CBX4.HEK293T 346 bp overlap
CBX8 1 dataset
ChIP A-549 ENCSR616MOB.CBX8.A-549 607 bp overlap
CTCF 2 datasets
ChIP HT-1080 GSE135580.CTCF.HT-1080 222 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.CTCF.K-562_enCRISPRi-LK 190 bp overlap
Crx 1 dataset
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
DPRX 1 dataset
Motif DE_60h DE_60h-DPRX_MA1480.2 9 bp overlap
Dmbx1 1 dataset
Motif DE_60h DE_60h-Dmbx1_MA0883.2 10 bp overlap
Dmrt1 2 datasets
Motif DE_60h DE_60h-Dmrt1_MA1603.2 9 bp overlap
Motif DE_60h DE_60h-Dmrt1_MA1603.2 9 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 216 bp overlap
ERG 1 dataset
ChIP VCaP GSE49091.ERG.VCaP 121 bp overlap
ESRRA 1 dataset
Motif DE_60h DE_60h-ESRRA_MA0592.4 9 bp overlap
ESRRG 1 dataset
ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 419 bp overlap
EZH2 8 datasets
ChIP A-1847 GSE95643.EZH2.A-1847 333 bp overlap
ChIP A-673 ENCSR179SAO.EZH2.A-673 257 bp overlap
ChIP Hep-3B2-1-7 GSE128137.EZH2.Hep-3B2-1-7 301 bp overlap
ChIP PC-3 ENCFF928VSN 485 bp overlap
ChIP RL_CPI169-10d GSE134136.EZH2.RL_CPI169-10d 132 bp overlap
ChIP RL_CPI169-10d GSE134136.EZH2.RL_CPI169-10d 442 bp overlap
ChIP THP-1 GSE135024.EZH2.THP-1 205 bp overlap
ChIP neural progenitor cell ENCFF472NFV 169 bp overlap
EZH2_phosphoT487 2 datasets
ChIP PC-3 ENCSR617RSQ.EZH2_phosphoT487.PC-3 894 bp overlap
ChIP PC-9 ENCSR702GMW.EZH2_phosphoT487.PC-9 300 bp overlap
Esrrg 1 dataset
Motif DE_60h DE_60h-Esrrg_MA0643.2 9 bp overlap
FOXA1 23 datasets
ChIP 22Rv1 GSE96652.FOXA1.22Rv1 268 bp overlap
ChIP 22Rv1_CST_Crispr GSE123618.FOXA1.22Rv1_CST_Crispr 166 bp overlap
ChIP 22Rv1_R1881 GSE80742.FOXA1.22Rv1_R1881 219 bp overlap
ChIP A1A3_Dex GSE112491.FOXA1.A1A3_Dex 200 bp overlap
ChIP MCF-7 GSE60270.FOXA1.MCF-7 168 bp overlap
ChIP MCF-7 ERP001226.FOXA1.MCF-7 133 bp overlap
ChIP MCF-7_4OH-Tam GSE75201.FOXA1.MCF-7_4OH-Tam 166 bp overlap
ChIP MCF-7_E2 GSE60270.FOXA1.MCF-7_E2 242 bp overlap
ChIP MCF-7_E2 GSE23852.FOXA1.MCF-7_E2 258 bp overlap
ChIP MCF-7_JC4693 GSE126004.FOXA1.MCF-7_JC4693 268 bp overlap
ChIP MCF-7_estrogen_ab2 GSE112969.FOXA1.MCF-7_estrogen_ab2 353 bp overlap
ChIP MCF-7_vehicle_ab2 GSE112969.FOXA1.MCF-7_vehicle_ab2 314 bp overlap
ChIP T-47D_8h GSE137579.FOXA1.T-47D_8h 180 bp overlap
ChIP T-47D_CR3flp GSE99479.FOXA1.T-47D_CR3flp 217 bp overlap
ChIP T-47D_DMSO GSE84593.FOXA1.T-47D_DMSO 326 bp overlap
ChIP T-47D_E2 GSE72249.FOXA1.T-47D_E2 199 bp overlap
ChIP T-47D_shRNF2 GSE137579.FOXA1.T-47D_shRNF2 238 bp overlap
ChIP T-47D_shRNF2_24h GSE137579.FOXA1.T-47D_shRNF2_24h 157 bp overlap
ChIP T-47D_shRNF2_45min GSE137579.FOXA1.T-47D_shRNF2_45min 220 bp overlap
ChIP T-47D_shRNF2_8h GSE137579.FOXA1.T-47D_shRNF2_8h 225 bp overlap
ChIP T-47D_shRNF2_8h GSE137579.FOXA1.T-47D_shRNF2_8h 162 bp overlap
ChIP VCaP_DHT24H GSE58428.FOXA1.VCaP_DHT24H 374 bp overlap
ChIP liver ENCFF749ERP 319 bp overlap
FOXA2 5 datasets
ChIP DE DE-FOXA2-1 1187 bp overlap
ChIP DE DE-FOXA2-2 1220 bp overlap
ChIP liver ENCFF877SFI 345 bp overlap
ChIP liver ENCSR310NYI.FOXA2.liver 199 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 273 bp overlap
FOXB1 1 dataset
Motif DE_60h DE_60h-FOXB1_MA0845.1 11 bp overlap
FOXF1 1 dataset
ChIP GIST-T1 GSE106624.FOXF1.GIST-T1 167 bp overlap
GATA2 5 datasets
ChIP LNCaP GSE38391.GATA2.LNCaP 145 bp overlap
ChIP LNCaP GSE52725.GATA2.LNCaP 145 bp overlap
ChIP LNCaP_CSFCS GSE69043.GATA2.LNCaP_CSFCS 242 bp overlap
ChIP VCaP_JQ1 GSE125236.GATA2.VCaP_JQ1 176 bp overlap
ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 281 bp overlap
GATA3 1 dataset
ChIP A1A3_Brg1KD_EtOH GSE112491.GATA3.A1A3_Brg1KD_EtOH 162 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 1157 bp overlap
ChIP DE DE-GATA4-2 1294 bp overlap
ChIP foregut GSE117136.GATA4.foregut 296 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 559 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 760 bp overlap
GATA6 9 datasets
ChIP AGS GSE51705.GATA6.AGS 185 bp overlap
ChIP DE DE-GATA6-1 1154 bp overlap
ChIP DE DE-GATA6-2 1272 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 773 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 434 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 287 bp overlap
ChIP foregut GSE117136.GATA6.foregut 319 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 349 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 342 bp overlap
GSC 1 dataset
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
GSC2 1 dataset
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
HNF4A 1 dataset
ChIP liver ERP002306.HNF4A.liver 135 bp overlap
INTS11 1 dataset
ChIP HeLa GSE125534.INTS11.HeLa 190 bp overlap
IRF7 1 dataset
Motif DE_60h DE_60h-IRF7_MA0772.2 13 bp overlap
JUND 2 datasets
ChIP liver ENCSR837GTK.JUND.liver 195 bp overlap
ChIP liver ENCSR196HGZ.JUND.liver 225 bp overlap
KLF4 1 dataset
ChIP HAP1 GSE130417.KLF4.HAP1 243 bp overlap
KMT2A 1 dataset
ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 201 bp overlap
MAX 1 dataset
ChIP WTC11 ENCFF223QFY 52 bp overlap
MSANTD3 1 dataset
Motif DE_60h DE_60h-MSANTD3_MA1523.2 7 bp overlap
MTF2 1 dataset
ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 260 bp overlap
NKX2-5 1 dataset
ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 235 bp overlap
NR3C1 1 dataset
ChIP T47D-A1-2_Dex GSE112491.NR3C1.T47D-A1-2_Dex 160 bp overlap
NR5A1 1 dataset
Motif DE_60h DE_60h-NR5A1_MA1540.3 12 bp overlap
NRIP1 2 datasets
ChIP MCF-7 ERP005838.NRIP1.MCF-7 126 bp overlap
ChIP MCF-7 ERP005838.NRIP1.MCF-7 125 bp overlap
Nr5A2 1 dataset
Motif DE_60h DE_60h-Nr5A2_MA0505.3 9 bp overlap
ONECUT1 3 datasets
ChIP H9 ERP004206.ONECUT1.H9 402 bp overlap
ChIP liver ERP002306.ONECUT1.liver 316 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 622 bp overlap
ONECUT2 1 dataset
ChIP AGS_Overexpression GSE113045.ONECUT2.AGS_Overexpression 238 bp overlap
OTX1 1 dataset
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
PHOX2B 1 dataset
ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 92 bp overlap
PITX1 1 dataset
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
PITX3 1 dataset
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
POU5F1 3 datasets
ChIP NCCIT GSE36134.POU5F1.NCCIT 376 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 438 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 433 bp overlap
RAD21 2 datasets
ChIP HAP1 GSE126634.RAD21.HAP1 296 bp overlap
ChIP HAP1 GSE152721.RAD21.HAP1 405 bp overlap
REST 3 datasets
ChIP liver ENCFF240FWT 485 bp overlap
ChIP liver ENCSR867WPH.REST.liver 243 bp overlap
ChIP liver ENCSR867WPH.REST.liver 396 bp overlap
RHOXF1 1 dataset
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
RNF2 2 datasets
ChIP A-549 ENCSR798EGJ.RNF2.A-549 625 bp overlap
ChIP SYO-1_shCt GSE139053.RNF2.SYO-1_shCt 477 bp overlap
RUNX1 1 dataset
ChIP VCaP_DHT24H GSE58428.RUNX1.VCaP_DHT24H 773 bp overlap
RXRA 1 dataset
ChIP liver ENCFF807CIA 387 bp overlap
SATB1 5 datasets
ChIP MCF-10A GSE123292.SATB1.MCF-10A 73 bp overlap
ChIP MCF-10A_CP GSE123292.SATB1.MCF-10A_CP 75 bp overlap
ChIP MCF-10A_ICRF GSE123292.SATB1.MCF-10A_ICRF 82 bp overlap
ChIP MCF-10A_N-term_CUT1 GSE123292.SATB1.MCF-10A_N-term_CUT1 117 bp overlap
ChIP MCF-10A_dHD GSE123292.SATB1.MCF-10A_dHD 194 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 196 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 1349 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 688 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 537 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 156 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 222 bp overlap
SNAI2 2 datasets
ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 250 bp overlap
ChIP SMS-CTR_shSNAI2 GSE137168.SNAI2.SMS-CTR_shSNAI2 185 bp overlap
SOX10 2 datasets
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 417 bp overlap
SOX17_M 2 datasets
ChIP DE_D2 DED2-SOX17-M_Batch_II 590 bp overlap
ChIP DE_D2 DED2-SOX17-M_Batch_II 494 bp overlap
SP1 1 dataset
ChIP liver ENCFF597LFJ 417 bp overlap
SP5_Zebrafish 1 dataset
ChIP HEK293_Zebrafish_dDBD GSE121316.SP5_Zebrafish.HEK293_Zebrafish_dDBD 154 bp overlap
SS18 1 dataset
ChIP Aska-SS GSE108025.SS18.Aska-SS 278 bp overlap
TAF1 7 datasets
ChIP liver ENCFF610UQP 411 bp overlap
ChIP liver ENCFF972HXJ 428 bp overlap
ChIP liver ENCFF972HXJ 537 bp overlap
ChIP liver ENCFF972HXJ 533 bp overlap
ChIP liver ENCFF972HXJ 330 bp overlap
ChIP liver ENCSR016BMM.TAF1.liver 242 bp overlap
ChIP liver ENCSR016BMM.TAF1.liver 244 bp overlap
UBN1 1 dataset
ChIP HeLa GSE45024.UBN1.HeLa 166 bp overlap
YY1 3 datasets
ChIP liver ENCFF400MBC 463 bp overlap
ChIP liver ENCFF400MBC 560 bp overlap
ChIP liver ENCSR994YLZ.YY1.liver 632 bp overlap
ZNF10 2 datasets
ChIP HEK293 ENCFF611ZJI 385 bp overlap
ChIP HEK293 ENCSR019WUS.ZNF10.HEK293 423 bp overlap
ZNF143 1 dataset
ChIP K-562 GSE39263.ZNF143.K-562 210 bp overlap
ZNF317 1 dataset
Motif DE_60h DE_60h-ZNF317_MA1593.2 8 bp overlap
ZNF736 1 dataset
ChIP HEK293T GSE78099.ZNF736.HEK293T 99 bp overlap
ZSCAN29 1 dataset
Motif DE_60h DE_60h-ZSCAN29_MA1602.2 11 bp overlap
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