chr7 : 144,873,055 – 144,873,791
736 bp 110 TFs 1 linked gene
This 736 bp open chromatin element is linked to TPK1 and is bound by 110 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
TPK1 37.5 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr7:144,868,055 – 144,878,791
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
110 transcription factors
Source
Cell type
ARNT2 2 datasets
Motif DE_48h DE_48h-ARNT2_MA1464.2 8 bp overlap
Motif DE_72h DE_72h-ARNT2_MA1464.2 8 bp overlap
ARNT::HIF1A 2 datasets
Motif DE_48h DE_48h-ARNTHIF1A_MA0259.2 5 bp overlap
Motif DE_72h DE_72h-ARNTHIF1A_MA0259.2 5 bp overlap
Arid5a 2 datasets
Motif DE_48h DE_48h-Arid5a_MA0602.2 8 bp overlap
Motif DE_60h DE_60h-Arid5a_MA0602.2 8 bp overlap
Arnt 2 datasets
Motif DE_48h DE_48h-Arnt_MA0004.1 6 bp overlap
Motif DE_72h DE_72h-Arnt_MA0004.1 6 bp overlap
BHLHE22 3 datasets
Motif DE_48h DE_48h-BHLHE22_MA1635.2 6 bp overlap
Motif DE_60h DE_60h-BHLHE22_MA1635.2 6 bp overlap
Motif DE_72h DE_72h-BHLHE22_MA1635.2 6 bp overlap
BMPR1A 1 dataset
ChIP HUVEC-C GSE60156.BMPR1A.HUVEC-C 219 bp overlap
CDX1 2 datasets
Motif DE_48h DE_48h-CDX1_MA0878.3 10 bp overlap
Motif DE_72h DE_72h-CDX1_MA0878.3 10 bp overlap
CDX2 2 datasets
Motif DE_48h DE_48h-CDX2_MA0465.3 8 bp overlap
Motif DE_72h DE_72h-CDX2_MA0465.3 8 bp overlap
CDX4 2 datasets
Motif DE_48h DE_48h-CDX4_MA1473.2 9 bp overlap
Motif DE_72h DE_72h-CDX4_MA1473.2 9 bp overlap
CHD2 4 datasets
ChIP A549 ENCFF389RCI 297 bp overlap
ChIP HepG2 ENCFF968LAV 317 bp overlap
ChIP K-562 ENCSR000EHD.CHD2.K-562 264 bp overlap
ChIP K562 ENCFF857WME 139 bp overlap
CLOCK 2 datasets
Motif DE_48h DE_48h-CLOCK_MA0819.3 7 bp overlap
Motif DE_72h DE_72h-CLOCK_MA0819.3 7 bp overlap
CTBP1 1 dataset
ChIP K-562 ENCSR201NQZ.CTBP1.K-562 276 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF364PUR 328 bp overlap
Crx 2 datasets
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap
DUX4 5 datasets
Motif DE_48h DE_48h-DUX4_MA0468.1 11 bp overlap
Motif DE_48h DE_48h-DUX4_MA0468.1 11 bp overlap
Motif DE_48h DE_48h-DUX4_MA0468.1 11 bp overlap
Motif DE_72h DE_72h-DUX4_MA0468.1 11 bp overlap
ChIP WA01 GSE94322.DUX4.WA01 294 bp overlap
DUXA 1 dataset
Motif DE_48h DE_48h-DUXA_MA0884.2 13 bp overlap
Dmbx1 2 datasets
Motif DE_48h DE_48h-Dmbx1_MA0883.2 10 bp overlap
Motif DE_72h DE_72h-Dmbx1_MA0883.2 10 bp overlap
Dux 2 datasets
Motif DE_48h DE_48h-Dux_MA0611.3 11 bp overlap
Motif DE_48h DE_48h-Dux_MA0611.3 11 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 261 bp overlap
ERF::FOXI1 3 datasets
Motif DE_48h DE_48h-ERFFOXI1_MA1935.2 10 bp overlap
Motif DE_60h DE_60h-ERFFOXI1_MA1935.2 10 bp overlap
Motif DE_72h DE_72h-ERFFOXI1_MA1935.2 10 bp overlap
ETV7 1 dataset
Motif DE_48h DE_48h-ETV7_MA1708.2 9 bp overlap
FOXA1 2 datasets
Motif DE_48h DE_48h-FOXA1_MA0148.5 8 bp overlap
Motif DE_60h DE_60h-FOXA1_MA0148.5 8 bp overlap
FOXA2 4 datasets
ChIP DE DE-FOXA2-1 536 bp overlap
ChIP DE DE-FOXA2-2 617 bp overlap
Motif DE_48h DE_48h-FOXA2_MA0047.4 8 bp overlap
Motif DE_60h DE_60h-FOXA2_MA0047.4 8 bp overlap
FOXA3 2 datasets
Motif DE_48h DE_48h-FOXA3_MA1683.2 7 bp overlap
Motif DE_60h DE_60h-FOXA3_MA1683.2 7 bp overlap
FOXB1 2 datasets
Motif DE_48h DE_48h-FOXB1_MA0845.1 11 bp overlap
Motif DE_60h DE_60h-FOXB1_MA0845.1 11 bp overlap
FOXC1 4 datasets
Motif DE_48h DE_48h-FOXC1_MA0032.2 11 bp overlap
Motif DE_48h DE_48h-FOXC1_MA0032.2 11 bp overlap
Motif DE_60h DE_60h-FOXC1_MA0032.2 11 bp overlap
Motif DE_72h DE_72h-FOXC1_MA0032.2 11 bp overlap
FOXC2 4 datasets
Motif DE_48h DE_48h-FOXC2_MA0846.2 11 bp overlap
Motif DE_48h DE_48h-FOXC2_MA0846.2 11 bp overlap
Motif DE_60h DE_60h-FOXC2_MA0846.2 11 bp overlap
Motif DE_72h DE_72h-FOXC2_MA0846.2 11 bp overlap
FOXD3 2 datasets
Motif DE_48h DE_48h-FOXD3_MA0041.3 14 bp overlap
Motif DE_72h DE_72h-FOXD3_MA0041.3 14 bp overlap
FOXF2 2 datasets
Motif DE_48h DE_48h-FOXF2_MA0030.2 9 bp overlap
Motif DE_60h DE_60h-FOXF2_MA0030.2 9 bp overlap
FOXI1 2 datasets
Motif DE_48h DE_48h-FOXI1_MA0042.2 7 bp overlap
Motif DE_60h DE_60h-FOXI1_MA0042.2 7 bp overlap
FOXP1 2 datasets
Motif DE_48h DE_48h-FOXP1_MA0481.4 7 bp overlap
Motif DE_60h DE_60h-FOXP1_MA0481.4 7 bp overlap
FOXP4 2 datasets
Motif DE_48h DE_48h-FOXP4_MA2117.1 7 bp overlap
Motif DE_60h DE_60h-FOXP4_MA2117.1 7 bp overlap
Foxq1 2 datasets
Motif DE_48h DE_48h-Foxq1_MA0040.2 10 bp overlap
Motif DE_72h DE_72h-Foxq1_MA0040.2 10 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 585 bp overlap
ChIP DE DE-GATA4-2 644 bp overlap
GATA6 4 datasets
ChIP DE DE-GATA6-1 468 bp overlap
ChIP DE DE-GATA6-2 636 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 736 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 261 bp overlap
GFI1B 1 dataset
ChIP K-562 ENCSR509GDT.GFI1B.K-562 131 bp overlap
GSC 2 datasets
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap
GSC2 2 datasets
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap
Gfi1B 2 datasets
Motif DE_48h DE_48h-Gfi1B_MA0483.2 10 bp overlap
Motif DE_72h DE_72h-Gfi1B_MA0483.2 10 bp overlap
HDAC1 1 dataset
ChIP K-562 ENCSR387UWP.HDAC1.K-562 277 bp overlap
HES6 2 datasets
Motif DE_48h DE_48h-HES6_MA1493.1 10 bp overlap
Motif DE_72h DE_72h-HES6_MA1493.1 10 bp overlap
Hoxa13 2 datasets
Motif DE_48h DE_48h-Hoxa13_MA0650.4 8 bp overlap
Motif DE_72h DE_72h-Hoxa13_MA0650.4 8 bp overlap
Hoxd13 2 datasets
Motif DE_48h DE_48h-Hoxd13_MA0909.4 7 bp overlap
Motif DE_72h DE_72h-Hoxd13_MA0909.4 7 bp overlap
IKZF1 4 datasets
Motif DE_48h DE_48h-IKZF1_MA1508.2 8 bp overlap
Motif DE_60h DE_60h-IKZF1_MA1508.2 8 bp overlap
Motif DE_72h DE_72h-IKZF1_MA1508.2 8 bp overlap
ChIP K-562 ENCSR395HWC.IKZF1.K-562 231 bp overlap
KLF1 2 datasets
Motif DE_48h DE_48h-KLF1_MA0493.3 8 bp overlap
Motif DE_72h DE_72h-KLF1_MA0493.3 8 bp overlap
KLF10 2 datasets
Motif DE_48h DE_48h-KLF10_MA1511.2 9 bp overlap
Motif DE_72h DE_72h-KLF10_MA1511.2 9 bp overlap
KLF14 2 datasets
Motif DE_48h DE_48h-KLF14_MA0740.2 9 bp overlap
Motif DE_72h DE_72h-KLF14_MA0740.2 9 bp overlap
KLF17 1 dataset
Motif DE_48h DE_48h-KLF17_MA1514.2 14 bp overlap
KLF2 2 datasets
Motif DE_48h DE_48h-KLF2_MA1515.2 8 bp overlap
Motif DE_72h DE_72h-KLF2_MA1515.2 8 bp overlap
KLF4 2 datasets
Motif DE_48h DE_48h-KLF4_MA0039.5 8 bp overlap
Motif DE_72h DE_72h-KLF4_MA0039.5 8 bp overlap
KLF5 2 datasets
Motif DE_48h DE_48h-KLF5_MA0599.1 10 bp overlap
Motif DE_72h DE_72h-KLF5_MA0599.1 10 bp overlap
L3MBTL2 2 datasets
ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 455 bp overlap
ChIP K562 ENCFF320EQC 422 bp overlap
MAX 4 datasets
Motif DE_48h DE_48h-MAX_MA0058.4 6 bp overlap
Motif DE_72h DE_72h-MAX_MA0058.4 6 bp overlap
ChIP K-562 ENCSR000EFV.MAX.K-562 139 bp overlap
ChIP K562 ENCFF110LJS 351 bp overlap
MEIS1 3 datasets
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MGA 2 datasets
ChIP K-562 ENCSR710WLO.MGA.K-562 281 bp overlap
ChIP K562 ENCFF140CEX 545 bp overlap
MLXIPL 2 datasets
Motif DE_48h DE_48h-MLXIPL_MA0664.2 8 bp overlap
Motif DE_72h DE_72h-MLXIPL_MA0664.2 8 bp overlap
MNT 2 datasets
Motif DE_48h DE_48h-MNT_MA0825.2 6 bp overlap
Motif DE_72h DE_72h-MNT_MA0825.2 6 bp overlap
MYC 3 datasets
Motif DE_48h DE_48h-MYC_MA0147.4 8 bp overlap
Motif DE_72h DE_72h-MYC_MA0147.4 8 bp overlap
ChIP K-562 ENCSR000EGJ.MYC.K-562 112 bp overlap
MYCN 2 datasets
Motif DE_48h DE_48h-MYCN_MA0104.5 8 bp overlap
Motif DE_72h DE_72h-MYCN_MA0104.5 8 bp overlap
MZF1 4 datasets
Motif DE_48h DE_48h-MZF1_MA0056.3 8 bp overlap
Motif DE_48h DE_48h-MZF1_MA0056.3 8 bp overlap
Motif DE_72h DE_72h-MZF1_MA0056.3 8 bp overlap
Motif DE_72h DE_72h-MZF1_MA0056.3 8 bp overlap
Mlxip 2 datasets
Motif DE_48h DE_48h-Mlxip_MA0622.2 6 bp overlap
Motif DE_72h DE_72h-Mlxip_MA0622.2 6 bp overlap
NFYA 1 dataset
Motif DE_48h DE_48h-NFYA_MA0060.4 8 bp overlap
NFYC 1 dataset
Motif DE_48h DE_48h-NFYC_MA1644.2 7 bp overlap
NR1D1 3 datasets
Motif DE_48h DE_48h-NR1D1_MA1531.2 14 bp overlap
Motif DE_60h DE_60h-NR1D1_MA1531.2 14 bp overlap
Motif DE_72h DE_72h-NR1D1_MA1531.2 14 bp overlap
NRF1 9 datasets
ChIP K-562 ENCSR494TDU.NRF1.K-562 449 bp overlap
ChIP K-562 ENCSR998AJK.NRF1.K-562 444 bp overlap
ChIP K-562 ENCSR837EYC.NRF1.K-562 210 bp overlap
ChIP K-562_Ab_R157-1-3D4 GSE97661.NRF1.K-562_Ab_R157-1-3D4 218 bp overlap
ChIP K-562_Ab_R157-1-3H1 GSE97661.NRF1.K-562_Ab_R157-1-3H1 119 bp overlap
ChIP K-562_Ab_R157-1-3H3 GSE97661.NRF1.K-562_Ab_R157-1-3H3 191 bp overlap
ChIP K562 ENCFF130SGK 228 bp overlap
ChIP K562 ENCFF689EWI 461 bp overlap
ChIP K562 ENCFF791UHF 459 bp overlap
Neurod2 3 datasets
Motif DE_48h DE_48h-Neurod2_MA1993.2 6 bp overlap
Motif DE_60h DE_60h-Neurod2_MA1993.2 6 bp overlap
Motif DE_72h DE_72h-Neurod2_MA1993.2 6 bp overlap
Npas2 2 datasets
Motif DE_48h DE_48h-Npas2_MA0626.2 8 bp overlap
Motif DE_72h DE_72h-Npas2_MA0626.2 8 bp overlap
Nr2e1 1 dataset
Motif DE_48h DE_48h-Nr2e1_MA0676.1 9 bp overlap
OTX1 2 datasets
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap
OTX2 2 datasets
Motif DE_48h DE_48h-OTX2_MA0712.3 7 bp overlap
Motif DE_72h DE_72h-OTX2_MA0712.3 7 bp overlap
Olig2 3 datasets
Motif DE_48h DE_48h-Olig2_MA1997.2 6 bp overlap
Motif DE_60h DE_60h-Olig2_MA1997.2 6 bp overlap
Motif DE_72h DE_72h-Olig2_MA1997.2 6 bp overlap
PATZ1 1 dataset
ChIP K-562 ENCSR549PVK.PATZ1.K-562 245 bp overlap
PBX1 1 dataset
Motif DE_48h DE_48h-PBX1_MA0070.2 9 bp overlap
PITX1 2 datasets
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap
PITX3 2 datasets
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap
RAD21 1 dataset
ChIP K562 ENCFF066JWO 303 bp overlap
RELA 1 dataset
Motif DE_48h DE_48h-RELA_MA0107.1 10 bp overlap
REST 3 datasets
ChIP A-549 ENCSR892DRK.REST.A-549 289 bp overlap
ChIP A549 ENCFF148AIS 488 bp overlap
ChIP K562 ENCFF758CZL 218 bp overlap
RHOXF1 2 datasets
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap
RUNX3 3 datasets
Motif DE_48h DE_48h-RUNX3_MA0684.3 8 bp overlap
Motif DE_60h DE_60h-RUNX3_MA0684.3 8 bp overlap
Motif DE_72h DE_72h-RUNX3_MA0684.3 8 bp overlap
SCRT1 2 datasets
Motif DE_48h DE_48h-SCRT1_MA0743.3 10 bp overlap
Motif DE_72h DE_72h-SCRT1_MA0743.3 10 bp overlap
SCRT2 2 datasets
Motif DE_48h DE_48h-SCRT2_MA0744.3 10 bp overlap
Motif DE_72h DE_72h-SCRT2_MA0744.3 10 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 515 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 396 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 438 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 201 bp overlap
SOX10 2 datasets
Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap
Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 220 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 592 bp overlap
SOX8 1 dataset
Motif DE_48h DE_48h-SOX8_MA0868.3 7 bp overlap
SP1 2 datasets
ChIP K-562 ENCSR991ELG.SP1.K-562 412 bp overlap
ChIP K562 ENCFF907BMO 153 bp overlap
SP5 1 dataset
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
SPIB 1 dataset
Motif DE_48h DE_48h-SPIB_MA0081.3 13 bp overlap
STAT1 3 datasets
Motif DE_48h DE_48h-STAT1_MA0137.4 9 bp overlap
Motif DE_60h DE_60h-STAT1_MA0137.4 9 bp overlap
Motif DE_72h DE_72h-STAT1_MA0137.4 9 bp overlap
Six3 3 datasets
Motif DE_48h DE_48h-Six3_MA0631.2 11 bp overlap
Motif DE_60h DE_60h-Six3_MA0631.2 11 bp overlap
Motif DE_72h DE_72h-Six3_MA0631.2 11 bp overlap
Sox6 2 datasets
Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap
Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap
Spi1 1 dataset
Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap
Stat5b 3 datasets
Motif DE_48h DE_48h-Stat5b_MA1625.2 9 bp overlap
Motif DE_60h DE_60h-Stat5b_MA1625.2 9 bp overlap
Motif DE_72h DE_72h-Stat5b_MA1625.2 9 bp overlap
TFAP4 3 datasets
Motif DE_48h DE_48h-TFAP4_MA0691.1 10 bp overlap
Motif DE_60h DE_60h-TFAP4_MA0691.1 10 bp overlap
Motif DE_72h DE_72h-TFAP4_MA0691.1 10 bp overlap
Tcf12 3 datasets
Motif DE_48h DE_48h-Tcf12_MA0521.3 6 bp overlap
Motif DE_60h DE_60h-Tcf12_MA0521.3 6 bp overlap
Motif DE_72h DE_72h-Tcf12_MA0521.3 6 bp overlap
Twist2 3 datasets
Motif DE_48h DE_48h-Twist2_MA0633.3 6 bp overlap
Motif DE_60h DE_60h-Twist2_MA0633.3 6 bp overlap
Motif DE_72h DE_72h-Twist2_MA0633.3 6 bp overlap
ZBTB33 2 datasets
ChIP K-562 ENCSR000BKF.ZBTB33.K-562 143 bp overlap
ChIP K562 ENCFF911VPU 241 bp overlap
ZKSCAN5 1 dataset
Motif DE_48h DE_48h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF140 1 dataset
Motif DE_48h DE_48h-ZNF140_MA1589.2 19 bp overlap
ZNF157 1 dataset
Motif DE_48h DE_48h-ZNF157_MA2331.1 21 bp overlap
ZNF282 2 datasets
Motif DE_48h DE_48h-ZNF282_MA1154.2 15 bp overlap
Motif DE_72h DE_72h-ZNF282_MA1154.2 15 bp overlap
ZNF449 2 datasets
Motif DE_48h DE_48h-ZNF449_MA1656.2 10 bp overlap
Motif DE_72h DE_72h-ZNF449_MA1656.2 10 bp overlap
ZNF740 2 datasets
Motif DE_48h DE_48h-ZNF740_MA0753.3 10 bp overlap
Motif DE_72h DE_72h-ZNF740_MA0753.3 10 bp overlap
Zic1::Zic2 3 datasets
Motif DE_48h DE_48h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_60h DE_60h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_72h DE_72h-Zic1Zic2_MA1628.2 7 bp overlap
Zic2 3 datasets
Motif DE_48h DE_48h-Zic2_MA1629.2 9 bp overlap
Motif DE_60h DE_60h-Zic2_MA1629.2 9 bp overlap
Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap
Zic3 3 datasets
Motif DE_48h DE_48h-Zic3_MA0697.3 7 bp overlap
Motif DE_60h DE_60h-Zic3_MA0697.3 7 bp overlap
Motif DE_72h DE_72h-Zic3_MA0697.3 7 bp overlap
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