chr5 : 146,331,495 – 146,331,720

225 bp 76 TFs 1 linked gene

This 225 bp open chromatin element is linked to POU4F3 and is bound by 76 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
POU4F3		7.1 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

76 transcription factors

ARID1A 2 datasets

ChIP MCF-7_DCDT GSE123284.ARID1A.MCF-7_DCDT 225 bp overlap

ChIP MCF-7_estrogen GSE123284.ARID1A.MCF-7_estrogen 225 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 225 bp overlap

ATF2 1 dataset

ChIP WA01 ENCSR000BQU.ATF2.WA01 124 bp overlap

BCOR 2 datasets

ChIP WA01 GSE104690.BCOR.WA01 220 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 196 bp overlap

BRD2 1 dataset

ChIP SK-MEL-147_JQ1 GSE94488.BRD2.SK-MEL-147_JQ1 52 bp overlap

BRD4 2 datasets

ChIP HEK293_Ctrl GSE129407.BRD4.HEK293_Ctrl 160 bp overlap

ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 225 bp overlap

Bcl11B 1 dataset

Motif ES_0h ES_0h-Bcl11B_MA1989.2 9 bp overlap

CDX1 1 dataset

Motif ES_0h ES_0h-CDX1_MA0878.3 10 bp overlap

CEBPA 8 datasets

Motif DE_12h DE_12h-CEBPA_MA0102.5 10 bp overlap

ChIP T-47D_progesterone GSE132649.CEBPA.T-47D_progesterone 205 bp overlap

ChIP THP-1_1-25D_24h GSE124032.CEBPA.THP-1_1-25D_24h 56 bp overlap

ChIP THP-1_1-25D_2h GSE124032.CEBPA.THP-1_1-25D_2h 58 bp overlap

ChIP THP-1_1-25D_8h GSE124032.CEBPA.THP-1_1-25D_8h 82 bp overlap

ChIP THP-1_EtOH_24h GSE124032.CEBPA.THP-1_EtOH_24h 84 bp overlap

ChIP THP-1_EtOH_2h GSE124032.CEBPA.THP-1_EtOH_2h 118 bp overlap

ChIP THP-1_EtOH_8h GSE124032.CEBPA.THP-1_EtOH_8h 84 bp overlap

CEBPB 5 datasets

Motif DE_12h DE_12h-CEBPB_MA0466.4 10 bp overlap

ChIP H1 ENCFF871PTR 174 bp overlap

ChIP MCF-7 ENCFF772ZTQ 169 bp overlap

ChIP MCF-7 ENCSR000BSR.CEBPB.MCF-7 105 bp overlap

ChIP WA01 ENCSR000EBV.CEBPB.WA01 169 bp overlap

CEBPE 1 dataset

Motif DE_12h DE_12h-CEBPE_MA0837.3 10 bp overlap

CEBPG 1 dataset

Motif DE_12h DE_12h-CEBPG_MA0838.1 10 bp overlap

CREBBP 1 dataset

ChIP MCF-7 ERP000901.CREBBP.MCF-7 198 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 225 bp overlap

CTCF 1 dataset

ChIP lymphoblast GSE155324.CTCF.lymphoblast 225 bp overlap

Cebpa 3 datasets

ChIP BLaER1 ENCFF031ISE 225 bp overlap

ChIP BLaER1 ENCFF093OYK 158 bp overlap

ChIP BLaER1 ENCFF460KDD 190 bp overlap

Crx 1 dataset

Motif DE_12h DE_12h-Crx_MA0467.3 6 bp overlap

DPF2 1 dataset

ChIP MCF-7 ENCSR234VCE.DPF2.MCF-7 194 bp overlap

Dmbx1 1 dataset

Motif DE_12h DE_12h-Dmbx1_MA0883.2 10 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 225 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 70 bp overlap

EP300 1 dataset

ChIP WA01 ENCSR000AUQ.EP300.WA01 146 bp overlap

ESR1 4 datasets

ChIP Ishikawa ENCSR000BQR.ESR1.Ishikawa 109 bp overlap

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 201 bp overlap

ChIP Ishikawa_siETV4-72h GSE129803.ESR1.Ishikawa_siETV4-72h 225 bp overlap

ChIP Ishikawa_siNTC-72h GSE129803.ESR1.Ishikawa_siNTC-72h 225 bp overlap

EZH2 3 datasets

ChIP WA01 ENCSR000ASY.EZH2.WA01 225 bp overlap

ChIP neural progenitor cell ENCFF018MKA 225 bp overlap

ChIP neural_progenitor ENCSR069DPL.EZH2.neural_progenitor 225 bp overlap

FOXA1 1 dataset

ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 103 bp overlap

GRHL2 5 datasets

ChIP MCF-7 GSE109820.GRHL2.MCF-7 225 bp overlap

ChIP MCF-7 GSE99680.GRHL2.MCF-7 225 bp overlap

ChIP MCF-7-WS8_VEH GSE113092.GRHL2.MCF-7-WS8_VEH 225 bp overlap

ChIP MCF-7_E2_45min GSE109820.GRHL2.MCF-7_E2_45min 225 bp overlap

ChIP T-47D GSE99680.GRHL2.T-47D 225 bp overlap

GSC 1 dataset

Motif DE_12h DE_12h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_12h DE_12h-GSC2_MA0891.2 6 bp overlap

Hand1::Tcf3 1 dataset

Motif ES_0h ES_0h-Hand1Tcf3_MA0092.2 9 bp overlap

JARID2 2 datasets

ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 225 bp overlap

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 225 bp overlap

JUN 2 datasets

ChIP DE_D1 S40-DE-d1-JUN-exp2 163 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 142 bp overlap

KLF17 1 dataset

ChIP HEK293 ENCSR065WUF.KLF17.HEK293 84 bp overlap

MAX 3 datasets

ChIP H1 ENCFF601FOM 139 bp overlap

ChIP H1 ENCFF914VQY 155 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 88 bp overlap

MED26 1 dataset

ChIP HEK293T GSE121024.MED26.HEK293T 202 bp overlap

MEIS1 1 dataset

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

MYCN 1 dataset

ChIP CHP-134 GSE129588.MYCN.CHP-134 68 bp overlap

NANOG 2 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 225 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 145 bp overlap

NR3C1 1 dataset

ChIP Ishikawa ENCSR000BJC.NR3C1.Ishikawa 101 bp overlap

OTX1 1 dataset

Motif DE_12h DE_12h-OTX1_MA0711.2 6 bp overlap

OTX2 2 datasets

Motif DE_12h DE_12h-OTX2_MA0712.3 7 bp overlap

ChIP WTC11 ENCFF634NAO 130 bp overlap

PITX1 1 dataset

Motif DE_12h DE_12h-PITX1_MA0682.3 6 bp overlap

PITX2 1 dataset

Motif DE_12h DE_12h-PITX2_MA1547.2 8 bp overlap

PITX3 1 dataset

Motif DE_12h DE_12h-PITX3_MA0714.2 6 bp overlap

POU5F1 1 dataset

ChIP HUES-8 GSE109524.POU5F1.HUES-8 225 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 225 bp overlap

RHOXF1 1 dataset

Motif DE_12h DE_12h-RHOXF1_MA0719.2 6 bp overlap

RNF2 3 datasets

ChIP HUES-64 GSE104059.RNF2.HUES-64 225 bp overlap

ChIP WA01 GSE104690.RNF2.WA01 225 bp overlap

ChIP WA09 GSE105028.RNF2.WA09 97 bp overlap

RUNX2 1 dataset

Motif ES_0h ES_0h-RUNX2_MA0511.2 9 bp overlap

Runx1 1 dataset

Motif ES_0h ES_0h-Runx1_MA0002.3 9 bp overlap

SAP30 1 dataset

ChIP WA01 ENCSR000ATR.SAP30.WA01 225 bp overlap

SIN3A 4 datasets

ChIP H1 ENCFF042ZSL 225 bp overlap

ChIP H1 ENCFF896IJG 205 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 225 bp overlap

ChIP WA01 ENCSR000BIS.SIN3A.WA01 161 bp overlap

SIX2 1 dataset

ChIP HEK GSE73865.SIX2.HEK 84 bp overlap

SMAD2 1 dataset

Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 225 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 225 bp overlap

SMAD2_3 2 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 225 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 216 bp overlap

SMARCA4 2 datasets

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 225 bp overlap

ChIP MCF-7 GSE123284.SMARCA4.MCF-7 225 bp overlap

SMARCB1 3 datasets

ChIP MCF-7 GSE123284.SMARCB1.MCF-7 225 bp overlap

ChIP MCF-7_DCDT GSE123284.SMARCB1.MCF-7_DCDT 225 bp overlap

ChIP MCF-7_estrogen GSE123284.SMARCB1.MCF-7_estrogen 221 bp overlap

SMARCD3 1 dataset

ChIP MCF-7 GSE124225.SMARCD3.MCF-7 147 bp overlap

SMARCE1 2 datasets

ChIP MCF-7 ENCFF890MHF 225 bp overlap

ChIP MCF-7 ENCSR431TLD.SMARCE1.MCF-7 168 bp overlap

SP1 2 datasets

ChIP H1 ENCFF263FUH 225 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 214 bp overlap

SP7 1 dataset

ChIP HEK293 ENCSR468IJT.SP7.HEK293 133 bp overlap

SUZ12 2 datasets

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 119 bp overlap

ChIP hiPSC GSE124903.SUZ12.hiPSC 61 bp overlap

TCF12 2 datasets

ChIP H1 ENCFF203EBH 159 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 157 bp overlap

TEAD4 2 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 204 bp overlap

ChIP H1 ENCFF778PAX 75 bp overlap

TRIM28 1 dataset

ChIP hESC GSE115387.TRIM28.hESC 213 bp overlap

VEZF1 1 dataset

Motif DE_12h DE_12h-VEZF1_MA1578.2 6 bp overlap

YY1 1 dataset

ChIP WA01 ENCSR000BKD.YY1.WA01 143 bp overlap

ZIC1 1 dataset

Motif ES_0h ES_0h-ZIC1_MA0696.1 14 bp overlap

ZIC2 1 dataset

ChIP HEK293 ENCFF033NQQ 104 bp overlap

ZIC4 1 dataset

Motif ES_0h ES_0h-ZIC4_MA0751.2 14 bp overlap

ZIC5 1 dataset

Motif ES_0h ES_0h-ZIC5_MA1584.2 15 bp overlap

ZNF189 1 dataset

Motif DE_12h DE_12h-ZNF189_MA1725.2 9 bp overlap

ZNF449 1 dataset

Motif ES_0h ES_0h-ZNF449_MA1656.2 10 bp overlap

ZNF707 1 dataset

Motif DE_12h DE_12h-ZNF707_MA1715.1 15 bp overlap

ZNF75D 1 dataset

Motif ES_0h ES_0h-ZNF75D_MA1601.2 12 bp overlap

ZNF766 1 dataset

Motif ES_0h ES_0h-ZNF766_MA2098.1 9 bp overlap

Zic2 1 dataset

Motif ES_0h ES_0h-Zic2_MA1629.2 9 bp overlap