chr4 : 71,765,488 – 71,766,176
688 bp 116 TFs 1 linked gene
This 688 bp open chromatin element is linked to NPFFR2 and is bound by 116 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
NPFFR2 266.1 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:71,760,488 – 71,771,176
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
116 transcription factors
Source
Cell type
ARID1A 1 dataset
ChIP HAP1 GSE108387.ARID1A.HAP1 360 bp overlap
Arid3a 1 dataset
Motif ES_0h ES_0h-Arid3a_MA0151.1 6 bp overlap
Atoh1 1 dataset
Motif ES_0h ES_0h-Atoh1_MA1467.3 7 bp overlap
BRD4 4 datasets
ChIP MM1-S GSE43743.BRD4.MM1-S 162 bp overlap
ChIP MM1-S GSE43743.BRD4.MM1-S 51 bp overlap
ChIP MM1-S_JQ1_5NM GSE42355.BRD4.MM1-S_JQ1_5NM 248 bp overlap
ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 197 bp overlap
CEBPA 1 dataset
Motif ES_0h ES_0h-CEBPA_MA0102.5 10 bp overlap
CEBPD 1 dataset
Motif ES_0h ES_0h-CEBPD_MA0836.3 8 bp overlap
CREB1 2 datasets
ChIP GM23338 ENCFF432ZEW 284 bp overlap
ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 217 bp overlap
CTBP2 1 dataset
ChIP WA01 ENCSR000EUO.CTBP2.WA01 270 bp overlap
CTCF 1 dataset
ChIP anterior-temporal-cortex_fetal GSE116825.CTCF.anterior-temporal-cortex_fetal 171 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF460KDD 213 bp overlap
E2F6 1 dataset
Motif ES_0h ES_0h-E2F6_MA0471.3 8 bp overlap
EP300 1 dataset
ChIP hESC GSE17917.EP300.hESC 543 bp overlap
ERF::FOXI1 1 dataset
Motif ES_0h ES_0h-ERFFOXI1_MA1935.2 10 bp overlap
ERF::FOXO1 1 dataset
Motif ES_0h ES_0h-ERFFOXO1_MA1936.2 12 bp overlap
ERG 1 dataset
ChIP VCaP_ETOH GSE49091.ERG.VCaP_ETOH 98 bp overlap
ETV2::FOXI1 1 dataset
Motif ES_0h ES_0h-ETV2FOXI1_MA1942.2 11 bp overlap
EWSR1-FLI1 1 dataset
Motif ES_0h ES_0h-EWSR1-FLI1_MA0149.1 18 bp overlap
FOXB1 1 dataset
Motif ES_0h ES_0h-FOXB1_MA0845.1 11 bp overlap
FOXC1 1 dataset
Motif ES_0h ES_0h-FOXC1_MA0032.2 11 bp overlap
FOXD2 1 dataset
Motif ES_0h ES_0h-FOXD2_MA0847.4 11 bp overlap
FOXE1 1 dataset
Motif ES_0h ES_0h-FOXE1_MA1487.3 12 bp overlap
FOXF2 1 dataset
Motif ES_0h ES_0h-FOXF2_MA0030.2 9 bp overlap
FOXH1 1 dataset
Motif ES_0h ES_0h-FOXH1_MA0479.2 8 bp overlap
FOXJ2::ELF1 1 dataset
Motif ES_0h ES_0h-FOXJ2ELF1_MA1952.2 11 bp overlap
FOXK1 1 dataset
Motif ES_0h ES_0h-FOXK1_MA0852.3 7 bp overlap
FOXK2 1 dataset
Motif ES_0h ES_0h-FOXK2_MA1103.3 7 bp overlap
FOXL1 1 dataset
Motif ES_0h ES_0h-FOXL1_MA0033.2 7 bp overlap
FOXO4 1 dataset
Motif ES_0h ES_0h-FOXO4_MA0848.1 7 bp overlap
FOXO6 1 dataset
Motif ES_0h ES_0h-FOXO6_MA0849.1 7 bp overlap
FOXP2 1 dataset
Motif ES_0h ES_0h-FOXP2_MA0593.2 9 bp overlap
FOXP3 1 dataset
Motif ES_0h ES_0h-FOXP3_MA0850.1 7 bp overlap
Foxf1 1 dataset
Motif ES_0h ES_0h-Foxf1_MA1606.2 7 bp overlap
Foxj3 1 dataset
Motif ES_0h ES_0h-Foxj3_MA0851.2 9 bp overlap
Foxl2 2 datasets
Motif ES_0h ES_0h-Foxl2_MA1607.2 10 bp overlap
Motif ES_0h ES_0h-Foxl2_MA1607.2 10 bp overlap
Foxo1 1 dataset
Motif ES_0h ES_0h-Foxo1_MA0480.3 7 bp overlap
Foxo3 1 dataset
Motif ES_0h ES_0h-Foxo3_MA0157.4 7 bp overlap
Foxq1 1 dataset
Motif ES_0h ES_0h-Foxq1_MA0040.2 10 bp overlap
GATA4 1 dataset
Motif ES_0h ES_0h-GATA4_MA0482.3 8 bp overlap
HAND2 2 datasets
Motif ES_0h ES_0h-HAND2_MA1638.2 6 bp overlap
Motif ES_0h ES_0h-HAND2_MA1638.2 6 bp overlap
HDAC2 2 datasets
ChIP H1 ENCFF939VKA 237 bp overlap
ChIP WA01 ENCSR000BNR.HDAC2.WA01 171 bp overlap
HIC2 1 dataset
Motif ES_0h ES_0h-HIC2_MA0738.2 6 bp overlap
HOXA3 1 dataset
Motif ES_0h ES_0h-HOXA3_MA2119.1 7 bp overlap
HOXA4 1 dataset
Motif ES_0h ES_0h-HOXA4_MA1496.2 7 bp overlap
HOXB4 1 dataset
Motif ES_0h ES_0h-HOXB4_MA1499.2 6 bp overlap
HOXC4 1 dataset
Motif ES_0h ES_0h-HOXC4_MA1504.2 6 bp overlap
HOXD4 1 dataset
Motif ES_0h ES_0h-HOXD4_MA1507.2 6 bp overlap
Hand1 1 dataset
Motif ES_0h ES_0h-Hand1_MA2123.1 9 bp overlap
IKZF1 2 datasets
Motif ES_0h ES_0h-IKZF1_MA1508.2 8 bp overlap
ChIP K-562 ENCSR395HWC.IKZF1.K-562 75 bp overlap
IRF2 1 dataset
Motif ES_0h ES_0h-IRF2_MA0051.2 16 bp overlap
IRF3 1 dataset
Motif ES_0h ES_0h-IRF3_MA1418.2 17 bp overlap
JUN 4 datasets
ChIP DE_D2 S02-DE-d2-JUN-exp1 475 bp overlap
ChIP ESC S24-ESC-d0-JUN-exp1 415 bp overlap
ChIP ESC S34-ESC-d0-JUN-exp2 481 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 454 bp overlap
KLF4 1 dataset
ChIP hiPSC GSE56567.KLF4.hiPSC 265 bp overlap
MED1 2 datasets
ChIP MM1-S_JQ1_50NM GSE49224.MED1.MM1-S_JQ1_50NM 78 bp overlap
ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 389 bp overlap
MEIS1 1 dataset
Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap
MEIS3 1 dataset
Motif ES_0h ES_0h-MEIS3_MA0775.2 7 bp overlap
MGA::EVX1 1 dataset
Motif ES_0h ES_0h-MGAEVX1_MA1960.2 11 bp overlap
MORC2 1 dataset
ChIP H9 GSE95374.MORC2.H9 386 bp overlap
NANOG 11 datasets
ChIP GM23338 ENCFF065NZG 150 bp overlap
ChIP GM23338 ENCSR061DGF.NANOG.GM23338 433 bp overlap
ChIP H1 ENCFF747ZPQ 241 bp overlap
ChIP HUES-8 GSE109524.NANOG.HUES-8 688 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 688 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 321 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 688 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 688 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 512 bp overlap
ChIP hESC GSE18292.NANOG.hESC 453 bp overlap
ChIP hESC GSE20650.NANOG.hESC 344 bp overlap
NEUROD1 1 dataset
Motif ES_0h ES_0h-NEUROD1_MA1109.2 8 bp overlap
NEUROG2 1 dataset
Motif ES_0h ES_0h-NEUROG2_MA1642.2 7 bp overlap
NFATC3 1 dataset
Motif ES_0h ES_0h-NFATC3_MA0625.3 6 bp overlap
NFIA 1 dataset
Motif ES_0h ES_0h-NFIA_MA0670.2 6 bp overlap
NFIC 1 dataset
Motif ES_0h ES_0h-NFIC_MA0161.3 7 bp overlap
NFIX 1 dataset
Motif ES_0h ES_0h-NFIX_MA0671.2 6 bp overlap
NIPBL 3 datasets
ChIP hESC GSE64758.NIPBL.hESC 308 bp overlap
ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 186 bp overlap
ChIP hESC_activin GSE64758.NIPBL.hESC_activin 297 bp overlap
NKX6-3 1 dataset
Motif ES_0h ES_0h-NKX6-3_MA1530.2 8 bp overlap
Neurod2 1 dataset
Motif ES_0h ES_0h-Neurod2_MA0668.3 8 bp overlap
Nfat5 1 dataset
Motif ES_0h ES_0h-Nfat5_MA0606.3 8 bp overlap
Nfatc1 1 dataset
Motif ES_0h ES_0h-Nfatc1_MA0624.3 6 bp overlap
Nfatc2 1 dataset
Motif ES_0h ES_0h-Nfatc2_MA0152.3 8 bp overlap
OTX2 1 dataset
ChIP WTC11 ENCFF634NAO 245 bp overlap
PHOX2B 1 dataset
Motif ES_0h ES_0h-PHOX2B_MA0681.3 12 bp overlap
POU1F1 1 dataset
Motif ES_0h ES_0h-POU1F1_MA0784.3 14 bp overlap
POU2F1 1 dataset
Motif ES_0h ES_0h-POU2F1_MA0785.2 9 bp overlap
POU2F1::SOX2 2 datasets
Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap
POU2F2 1 dataset
Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap
POU2F3 1 dataset
Motif ES_0h ES_0h-POU2F3_MA0627.3 9 bp overlap
POU3F1 1 dataset
Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap
POU3F2 1 dataset
Motif ES_0h ES_0h-POU3F2_MA0787.1 12 bp overlap
POU3F3 1 dataset
Motif ES_0h ES_0h-POU3F3_MA0788.1 13 bp overlap
POU3F4 1 dataset
Motif ES_0h ES_0h-POU3F4_MA0789.1 9 bp overlap
POU4F2 1 dataset
Motif ES_0h ES_0h-POU4F2_MA0683.2 15 bp overlap
POU5F1 14 datasets
Motif ES_0h ES_0h-POU5F1_MA1115.2 7 bp overlap
ChIP GM23338 ENCFF333SNB 311 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 688 bp overlap
ChIP NCCIT GSE36134.POU5F1.NCCIT 460 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 649 bp overlap
ChIP OSKM GSE81899.POU5F1.OSKM 302 bp overlap
ChIP WA09 GSE105028.POU5F1.WA09 491 bp overlap
ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 363 bp overlap
ChIP hESC ENCSR264RJX.POU5F1.hESC 372 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 235 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 576 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 148 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 105 bp overlap
ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 366 bp overlap
POU5F1B 1 dataset
Motif ES_0h ES_0h-POU5F1B_MA0792.1 9 bp overlap
Pou5f1::Sox2 2 datasets
Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap
Prdm5 1 dataset
Motif ES_0h ES_0h-Prdm5_MA1999.2 11 bp overlap
Ptf1A 1 dataset
Motif ES_0h ES_0h-Ptf1A_MA1618.2 9 bp overlap
RAD21 2 datasets
ChIP HAP1 GSE152721.RAD21.HAP1 183 bp overlap
ChIP SLK_CTCF-KD GSE138105.RAD21.SLK_CTCF-KD 365 bp overlap
RELB 1 dataset
Motif ES_0h ES_0h-RELB_MA1117.2 7 bp overlap
RNF2 2 datasets
ChIP fibroblast GSE139053.RNF2.fibroblast 152 bp overlap
ChIP fibroblast GSE139053.RNF2.fibroblast 252 bp overlap
RUNX1 1 dataset
ChIP epididymis_HEE GSE109061.RUNX1.epididymis_HEE 154 bp overlap
Rhox11 1 dataset
Motif ES_0h ES_0h-Rhox11_MA0629.2 9 bp overlap
SALL3 1 dataset
ChIP hiPSC GSE104863.SALL3.hiPSC 192 bp overlap
SCRT1 1 dataset
Motif ES_0h ES_0h-SCRT1_MA0743.3 10 bp overlap
SMAD2 1 dataset
Motif ES_0h ES_0h-SMAD2_MA1964.2 6 bp overlap
SMAD3 3 datasets
ChIP BG03 GSE21614.SMAD3.BG03 268 bp overlap
ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 288 bp overlap
ChIP hESC_DIFF_D0 GSE75297.SMAD3.hESC_DIFF_D0 204 bp overlap
SMARCA4 2 datasets
ChIP hiPSC GSE124903.SMARCA4.hiPSC 365 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 528 bp overlap
SMARCB1 2 datasets
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 277 bp overlap
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 312 bp overlap
SMARCC1 1 dataset
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 682 bp overlap
SOX10 1 dataset
Motif ES_0h ES_0h-SOX10_MA0442.3 6 bp overlap
SOX2 3 datasets
ChIP hESC GSE18292.SOX2.hESC 141 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 484 bp overlap
ChIP hiPSC_3s2 GSE81899.SOX2.hiPSC_3s2 300 bp overlap
SP5 2 datasets
Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap
Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap
STAT1::STAT2 1 dataset
Motif ES_0h ES_0h-STAT1STAT2_MA0517.2 13 bp overlap
Stat2 1 dataset
Motif ES_0h ES_0h-Stat2_MA1623.2 10 bp overlap
TBX19 1 dataset
Motif ES_0h ES_0h-TBX19_MA0804.2 17 bp overlap
TCF3 1 dataset
ChIP NPC GSE154479.TCF3.NPC 330 bp overlap
TEAD1 1 dataset
ChIP WTC11 ENCFF502QUV 283 bp overlap
TFAP4::ETV1 1 dataset
Motif ES_0h ES_0h-TFAP4ETV1_MA1966.2 13 bp overlap
TFAP4::FLI1 1 dataset
Motif ES_0h ES_0h-TFAP4FLI1_MA1967.2 14 bp overlap
YY1 1 dataset
ChIP RH4_DMSO-6H GSE116344.YY1.RH4_DMSO-6H 154 bp overlap
ZIM3 1 dataset
Motif ES_0h ES_0h-ZIM3_MA1709.2 11 bp overlap
ZNF207 1 dataset
ChIP WA09 GSE118632.ZNF207.WA09 402 bp overlap
ZNF317 1 dataset
Motif ES_0h ES_0h-ZNF317_MA1593.2 8 bp overlap
ZNF382 1 dataset
Motif ES_0h ES_0h-ZNF382_MA1594.1 24 bp overlap
ZNF462 4 datasets
ChIP GM23338 ENCFF896CCA 214 bp overlap
ChIP GM23338 ENCFF896CCA 249 bp overlap
ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 194 bp overlap
ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 291 bp overlap
ZNF558 1 dataset
Motif ES_0h ES_0h-ZNF558_MA2335.1 29 bp overlap
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