chr2 : 170,813,589 – 170,814,073
484 bp 79 TFs 3 linked genes
This 484 bp open chromatin element is linked to GAD1, ENSG00000235934, and ENSG00000286611 and is bound by 79 transcription factors.
Linked Genes
3 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
GAD1 2.0 kb Proximal Proximity
ENSG00000235934 3.8 kb Proximal Proximity
ENSG00000286611 7.2 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr2:170,808,589 – 170,819,073
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
79 transcription factors
Source
Cell type
AR 2 datasets
ChIP LNCaP-abl GSE39459.AR.LNCaP-abl 112 bp overlap
ChIP WTC11 ENCFF267GQJ 194 bp overlap
ARID2 1 dataset
ChIP HepG2 ENCFF317ZHO 60 bp overlap
ARID4A 1 dataset
ChIP HepG2 ENCFF142DIE 110 bp overlap
ASH2L 1 dataset
ChIP WA01 ENCSR850KIP.ASH2L.WA01 484 bp overlap
BCOR 3 datasets
ChIP WA01 GSE104690.BCOR.WA01 309 bp overlap
ChIP WA01 GSE104690.BCOR.WA01 63 bp overlap
ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 484 bp overlap
BHLHE40 2 datasets
ChIP HepG2 ENCFF961RID 186 bp overlap
ChIP HepG2 ENCFF961RID 297 bp overlap
BRD1 1 dataset
ChIP HUES-64 GSE104059.BRD1.HUES-64 404 bp overlap
BRD4 5 datasets
ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 173 bp overlap
ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 195 bp overlap
ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 260 bp overlap
ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 190 bp overlap
ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 186 bp overlap
CBX8 1 dataset
ChIP A-549 ENCSR616MOB.CBX8.A-549 377 bp overlap
CENPX 1 dataset
ChIP HepG2 ENCFF516PXX 265 bp overlap
CHCHD3 1 dataset
ChIP HepG2 ENCFF430RKB 59 bp overlap
CHD1 1 dataset
ChIP WA01 ENCSR000AQK.CHD1.WA01 203 bp overlap
CREBBP_M768 1 dataset
ChIP NCI-H3396_E2 GSE32349.CREBBP_M768.NCI-H3396_E2 96 bp overlap
CTBP2 1 dataset
ChIP WA01 ENCSR000EUO.CTBP2.WA01 248 bp overlap
CTCF 10 datasets
ChIP CD14 ENCSR000ATN.CTCF.CD14 180 bp overlap
ChIP HCT-116 GSE131606.CTCF.HCT-116 330 bp overlap
ChIP MCF-10A GSE98551.CTCF.MCF-10A 57 bp overlap
ChIP cardiac-muscle ENCSR713SXF.CTCF.cardiac-muscle 198 bp overlap
ChIP cortical-interneuron_KCl-neg_JQ1-neg GSE117508.CTCF.cortical-interneuron_KCl-neg_JQ1-neg 409 bp overlap
ChIP cortical-interneuron_KCl-neg_JQ1-pos GSE117508.CTCF.cortical-interneuron_KCl-neg_JQ1-pos 331 bp overlap
ChIP cortical-interneuron_KCl-pos_JQ1-pos GSE117508.CTCF.cortical-interneuron_KCl-pos_JQ1-pos 368 bp overlap
ChIP cortical-interneuron_KCl-pos_JQ1-pos GSE117508.CTCF.cortical-interneuron_KCl-pos_JQ1-pos 63 bp overlap
ChIP hESC_D2 GSE116862.CTCF.hESC_D2 189 bp overlap
ChIP osteoblast ENCSR000APF.CTCF.osteoblast 170 bp overlap
CTCFL 1 dataset
Motif DE_24h DE_24h-CTCFL_MA1102.3 8 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF031ISE 251 bp overlap
E2F6 2 datasets
ChIP H1 ENCFF785DWK 205 bp overlap
ChIP WA01 ENCSR000BSI.E2F6.WA01 113 bp overlap
EGR2 1 dataset
ChIP HEK293 ENCFF336LFH 257 bp overlap
ETS1 1 dataset
ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 182 bp overlap
EZH2 38 datasets
ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 484 bp overlap
ChIP A673 ENCFF790MVL 311 bp overlap
ChIP A673 ENCFF955JRZ 311 bp overlap
ChIP B-cell ENCSR000AUZ.EZH2.B-cell 71 bp overlap
ChIP GM23248 ENCFF404ZHM 114 bp overlap
ChIP GM23248 ENCSR131FFJ.EZH2.GM23248 149 bp overlap
ChIP GM23248 ENCSR131FFJ.EZH2.GM23248 267 bp overlap
ChIP GM23338 ENCFF613YON 286 bp overlap
ChIP H1 ENCFF232NZA 484 bp overlap
ChIP HUVEC-C_VEGF_12h GSE109625.EZH2.HUVEC-C_VEGF_12h 94 bp overlap
ChIP Hep-G2 ENCSR000ARI.EZH2.Hep-G2 315 bp overlap
ChIP LNCaP GSE39459.EZH2.LNCaP 298 bp overlap
ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 484 bp overlap
ChIP RCH-ACV GSE135024.EZH2.RCH-ACV 324 bp overlap
ChIP SK-N-MC ENCFF674XUJ 295 bp overlap
ChIP T98G GSE112240.EZH2.T98G 96 bp overlap
ChIP THP-1 GSE135024.EZH2.THP-1 469 bp overlap
ChIP dermal-fibroblast_Transformed GSE126396.EZH2.dermal-fibroblast_Transformed 150 bp overlap
ChIP dermal-fibroblast_Untransformed GSE126396.EZH2.dermal-fibroblast_Untransformed 155 bp overlap
ChIP dermal-fibroblast_Untransformed GSE126396.EZH2.dermal-fibroblast_Untransformed 116 bp overlap
ChIP endothelial cell of umbilical vein ENCFF539AKL 484 bp overlap
ChIP endothelial cell of umbilical vein ENCFF539AKL 202 bp overlap
ChIP epithelial_mammary ENCSR000ARE.EZH2.epithelial_mammary 436 bp overlap
ChIP fibroblast of dermis ENCFF029VZK 484 bp overlap
ChIP fibroblast of dermis ENCFF029VZK 359 bp overlap
ChIP fibroblast of lung ENCFF479BAW 456 bp overlap
ChIP fibroblast of lung ENCFF479BAW 209 bp overlap
ChIP fibroblast_DERMAL ENCSR000ASE.EZH2.fibroblast_DERMAL 484 bp overlap
ChIP hepatocyte ENCFF552DZB 433 bp overlap
ChIP hepatocyte ENCFF552DZB 484 bp overlap
ChIP keratinocyte ENCFF070STK 298 bp overlap
ChIP keratinocyte ENCFF070STK 112 bp overlap
ChIP mammary epithelial cell ENCFF224GAI 192 bp overlap
ChIP myotube ENCSR000ASZ.EZH2.myotube 192 bp overlap
ChIP myotube ENCSR000ASZ.EZH2.myotube 107 bp overlap
ChIP neural progenitor cell ENCFF472NFV 242 bp overlap
ChIP neural progenitor cell ENCFF472NFV 96 bp overlap
ChIP skeletal muscle myoblast ENCFF338LNF 383 bp overlap
EZH2_phosphoT487 1 dataset
ChIP OCI-Ly7 ENCSR565XSL.EZH2_phosphoT487.OCI-Ly7 120 bp overlap
GATA6 5 datasets
ChIP DE_D1 S09-DE-d1-GATA6-exp1 267 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 341 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 349 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 484 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 384 bp overlap
GTF3C2 1 dataset
ChIP H9 GSE94418.GTF3C2.H9 216 bp overlap
HDAC2 1 dataset
ChIP WA01 ENCSR000AVB.HDAC2.WA01 230 bp overlap
HIF1A 1 dataset
ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 323 bp overlap
HIF3A 1 dataset
ChIP Hep-3B2-1-7 GSE129491.HIF3A.Hep-3B2-1-7 283 bp overlap
HMGXB4 1 dataset
ChIP WTC11 ENCFF962POR 61 bp overlap
IKZF1 1 dataset
ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 121 bp overlap
IRF4 1 dataset
ChIP T-cell GSE136853.IRF4.T-cell 219 bp overlap
JARID2 2 datasets
ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 484 bp overlap
ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 484 bp overlap
JUN 2 datasets
ChIP DE_D1 S40-DE-d1-JUN-exp2 256 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 169 bp overlap
KDM1A 2 datasets
ChIP H1 ENCFF696SGD 249 bp overlap
ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 147 bp overlap
KDM2A 1 dataset
ChIP HepG2 ENCFF491GTR 56 bp overlap
KDM4A 1 dataset
ChIP WA01 ENCSR000AVC.KDM4A.WA01 408 bp overlap
KLF4 1 dataset
ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 168 bp overlap
LIN54 1 dataset
ChIP HepG2 ENCFF662XDE 214 bp overlap
MAX 1 dataset
ChIP WTC11 ENCFF223QFY 294 bp overlap
MAZ 2 datasets
Motif DE_24h DE_24h-MAZ_MA1522.2 8 bp overlap
Motif DE_24h DE_24h-MAZ_MA1522.2 8 bp overlap
MED1 1 dataset
ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 85 bp overlap
MIER1 1 dataset
ChIP K-562 ENCSR426MDV.MIER1.K-562 167 bp overlap
MNT 1 dataset
ChIP K562 ENCFF820IGH 85 bp overlap
NANOG 2 datasets
ChIP WA09 GSE105028.NANOG.WA09 123 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 246 bp overlap
NIPBL 2 datasets
ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 260 bp overlap
ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 306 bp overlap
PARP1 1 dataset
ChIP MCF-10A GSE93038.PARP1.MCF-10A 385 bp overlap
PATZ1 1 dataset
Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap
PCGF2 1 dataset
ChIP fibroblast_OHT GSE55605.PCGF2.fibroblast_OHT 85 bp overlap
POU5F1 4 datasets
ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 149 bp overlap
ChIP DE_D1 DED1-OCT4_Batch_II 439 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 170 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 141 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 241 bp overlap
RAD21 2 datasets
ChIP HEK293_siE1A-TAZ GSE130135.RAD21.HEK293_siE1A-TAZ 177 bp overlap
ChIP neural ENCSR198ZYJ.RAD21.neural 58 bp overlap
RBBP5 1 dataset
ChIP WA01 ENCSR000AQC.RBBP5.WA01 356 bp overlap
RBM39 2 datasets
ChIP Hep-G2 GSE120104.RBM39.Hep-G2 257 bp overlap
ChIP HepG2 ENCFF084YZE 484 bp overlap
REST 18 datasets
ChIP A-549 ENCSR000BQP.REST.A-549 215 bp overlap
ChIP CD4 GSE49570.REST.CD4 302 bp overlap
ChIP GM12878 ENCSR000BGF.REST.GM12878 92 bp overlap
ChIP GM23338 ENCSR871KYB.REST.GM23338 142 bp overlap
ChIP GP5D GSE51234.REST.GP5D 185 bp overlap
ChIP Hep-G2 ENCSR000BOT.REST.Hep-G2 249 bp overlap
ChIP Ishikawa ENCSR000BUU.REST.Ishikawa 225 bp overlap
ChIP K-562 ENCSR000BMW.REST.K-562 274 bp overlap
ChIP K562 ENCFF758CZL 129 bp overlap
ChIP MCF-7 ENCSR000BSP.REST.MCF-7 84 bp overlap
ChIP PANC-1 ENCSR000BPK.REST.PANC-1 186 bp overlap
ChIP PANC-1 ENCSR000BUP.REST.PANC-1 100 bp overlap
ChIP PFSK1 ENCSR000BOX.REST.PFSK1 69 bp overlap
ChIP WA01 ENCSR000BHM.REST.WA01 56 bp overlap
ChIP WA01 ENCSR663WAR.REST.WA01 147 bp overlap
ChIP colorectal-cancer_CRC121_intact GSE112555.REST.colorectal-cancer_CRC121_intact 413 bp overlap
ChIP liver ENCSR893QWP.REST.liver 410 bp overlap
ChIP liver ENCSR867WPH.REST.liver 70 bp overlap
RNF2 5 datasets
ChIP A-549 ENCSR798EGJ.RNF2.A-549 353 bp overlap
ChIP GM12878 ENCSR679FAB.RNF2.GM12878 98 bp overlap
ChIP HUES-64 GSE104059.RNF2.HUES-64 400 bp overlap
ChIP SYO-1_shCt GSE139053.RNF2.SYO-1_shCt 160 bp overlap
ChIP WA01 GSE104690.RNF2.WA01 254 bp overlap
RYBP 1 dataset
ChIP WA01 GSE104690.RYBP.WA01 460 bp overlap
SAP30 1 dataset
ChIP WA01 ENCSR000ATR.SAP30.WA01 342 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 115 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 484 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 467 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 484 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 444 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 267 bp overlap
SMARCA4 1 dataset
ChIP Aska-SS GSE108025.SMARCA4.Aska-SS 164 bp overlap
SMARCC1 1 dataset
ChIP TTC-549_NoDox GSE71504.SMARCC1.TTC-549_NoDox 149 bp overlap
SMC1 1 dataset
ChIP HCT-116 GSE131606.SMC1.HCT-116 203 bp overlap
SREBP2 1 dataset
ChIP monocyte GSE129202.SREBP2.monocyte 110 bp overlap
SS18 1 dataset
ChIP Aska-SS GSE108025.SS18.Aska-SS 214 bp overlap
SUZ12 2 datasets
ChIP LNCaP-abl GSE39459.SUZ12.LNCaP-abl 242 bp overlap
ChIP hiPSC_WT GSE124903.SUZ12.hiPSC_WT 484 bp overlap
TFAP2C 1 dataset
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 309 bp overlap
TP53 2 datasets
ChIP H9 GSE142050.TP53.H9 215 bp overlap
ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 284 bp overlap
TRIM22 1 dataset
ChIP GM12878 ENCSR637QAM.TRIM22.GM12878 443 bp overlap
USF2 1 dataset
ChIP K-562 GSE111469.USF2.K-562 197 bp overlap
WIZ 1 dataset
ChIP HepG2 ENCFF559CYZ 64 bp overlap
ZBTB20 1 dataset
ChIP HepG2 ENCFF200JRV 299 bp overlap
ZBTB33 1 dataset
ChIP K-562 ENCSR876GXA.ZBTB33.K-562 268 bp overlap
ZBTB7B 1 dataset
ChIP HepG2 ENCFF763OCV 377 bp overlap
ZBTB8A 2 datasets
ChIP HEK293 ENCFF303WRD 374 bp overlap
ChIP HEK293 ENCSR481FEC.ZBTB8A.HEK293 425 bp overlap
ZFHX2 1 dataset
ChIP HEK293 ENCFF167TUA 391 bp overlap
ZNF148 1 dataset
Motif DE_24h DE_24h-ZNF148_MA1653.2 10 bp overlap
ZNF263 1 dataset
ChIP K-562 ENCSR000EWN.ZNF263.K-562 282 bp overlap
ZNF3 1 dataset
ChIP K-562 ENCSR195QFV.ZNF3.K-562 129 bp overlap
ZNF407 1 dataset
ChIP Hep-G2 ENCSR005WGY.ZNF407.Hep-G2 146 bp overlap
ZSCAN21 1 dataset
ChIP HepG2 ENCFF676MFO 252 bp overlap
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