chr2 : 165,956,573 – 165,957,634
1,061 bp 111 TFs 2 linked genes
This 1.1 kb open chromatin element is linked to SCN1A-AS1 and TTC21B and is bound by 111 transcription factors.
Linked Genes
2 genes
Distance
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SCN1A-AS1 at TSS At TSS Proximity
TTC21B 2.8 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr2:165,951,573 – 165,962,634
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
111 transcription factors
Source
Cell type
AR 1 dataset
ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 157 bp overlap
ASCL1 4 datasets
Motif DE_12h DE_12h-ASCL1_MA1100.3 8 bp overlap
Motif DE_12h DE_12h-ASCL1_MA1631.2 9 bp overlap
Motif ES_0h ES_0h-ASCL1_MA1100.3 8 bp overlap
Motif ES_0h ES_0h-ASCL1_MA1631.2 9 bp overlap
ATF1 1 dataset
ChIP HCT-116 GSE130477.ATF1.HCT-116 427 bp overlap
Ahr::Arnt 2 datasets
Motif DE_12h DE_12h-AhrArnt_MA0006.2 5 bp overlap
Motif ES_0h ES_0h-AhrArnt_MA0006.2 5 bp overlap
Ascl2 2 datasets
Motif DE_12h DE_12h-Ascl2_MA0816.1 10 bp overlap
Motif ES_0h ES_0h-Ascl2_MA0816.1 10 bp overlap
BAF155 1 dataset
ChIP VCaP_shARID1A GSE110655.BAF155.VCaP_shARID1A 299 bp overlap
BHLHE22 2 datasets
Motif DE_12h DE_12h-BHLHE22_MA1635.2 6 bp overlap
Motif ES_0h ES_0h-BHLHE22_MA1635.2 6 bp overlap
BRD4 2 datasets
ChIP 22Rv1_DHT-DMSO GSE118247.BRD4.22Rv1_DHT-DMSO 251 bp overlap
ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 188 bp overlap
CTCF 4 datasets
Motif DE_12h DE_12h-CTCF_MA0139.2 15 bp overlap
Motif DE_12h DE_12h-CTCF_MA1930.2 33 bp overlap
Motif DE_24h DE_24h-CTCF_MA0139.2 15 bp overlap
Motif DE_24h DE_24h-CTCF_MA1930.2 33 bp overlap
CTCFL 3 datasets
Motif DE_12h DE_12h-CTCFL_MA1102.3 8 bp overlap
Motif DE_48h DE_48h-CTCFL_MA1102.3 8 bp overlap
ChIP K-562 GSE70764.CTCFL.K-562 146 bp overlap
DNMT3B 1 dataset
ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 211 bp overlap
E2F6 1 dataset
Motif DE_12h DE_12h-E2F6_MA0471.3 8 bp overlap
E2F8 1 dataset
Motif DE_12h DE_12h-E2F8_MA0865.3 9 bp overlap
EGR1 1 dataset
Motif DE_12h DE_12h-EGR1_MA0162.5 10 bp overlap
EGR3 2 datasets
Motif DE_12h DE_12h-EGR3_MA0732.2 11 bp overlap
Motif ES_0h ES_0h-EGR3_MA0732.2 11 bp overlap
EGR4 3 datasets
Motif DE_12h DE_12h-EGR4_MA0733.2 11 bp overlap
Motif DE_12h DE_12h-EGR4_MA0733.2 11 bp overlap
Motif ES_0h ES_0h-EGR4_MA0733.2 11 bp overlap
ERF::NHLH1 2 datasets
Motif DE_12h DE_12h-ERFNHLH1_MA1938.2 16 bp overlap
Motif ES_0h ES_0h-ERFNHLH1_MA1938.2 16 bp overlap
ERG 1 dataset
ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 499 bp overlap
ESR1 4 datasets
ChIP Ishikawa GSE99905.ESR1.Ishikawa 208 bp overlap
ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 300 bp overlap
ChIP MCF-7_Veh_OA GSE93510.ESR1.MCF-7_Veh_OA 505 bp overlap
ChIP breast_tumor_Male_10 GSE104399.ESR1.breast_tumor_Male_10 183 bp overlap
FEZF2 2 datasets
Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap
Motif ES_0h ES_0h-FEZF2_MA2341.1 8 bp overlap
FIGLA 2 datasets
Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap
Motif DE_24h DE_24h-FIGLA_MA0820.2 6 bp overlap
FOXA2 1 dataset
ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 415 bp overlap
GCM1 2 datasets
Motif DE_12h DE_12h-GCM1_MA0646.2 10 bp overlap
Motif ES_0h ES_0h-GCM1_MA0646.2 10 bp overlap
GLIS1 2 datasets
Motif DE_12h DE_12h-GLIS1_MA0735.2 15 bp overlap
Motif DE_48h DE_48h-GLIS1_MA0735.2 15 bp overlap
HES1 2 datasets
Motif DE_12h DE_12h-HES1_MA1099.3 8 bp overlap
Motif ES_0h ES_0h-HES1_MA1099.3 8 bp overlap
HES5 2 datasets
Motif DE_12h DE_12h-HES5_MA0821.2 10 bp overlap
Motif ES_0h ES_0h-HES5_MA0821.2 10 bp overlap
HEXIM1 1 dataset
ChIP HCT-116 GSE72622.HEXIM1.HCT-116 248 bp overlap
HEY1 2 datasets
Motif DE_12h DE_12h-HEY1_MA0823.1 10 bp overlap
Motif ES_0h ES_0h-HEY1_MA0823.1 10 bp overlap
KLF11 2 datasets
Motif DE_12h DE_12h-KLF11_MA1512.2 10 bp overlap
Motif DE_24h DE_24h-KLF11_MA1512.2 10 bp overlap
KLF12 2 datasets
Motif DE_12h DE_12h-KLF12_MA0742.2 9 bp overlap
Motif DE_24h DE_24h-KLF12_MA0742.2 9 bp overlap
KLF13 1 dataset
Motif DE_12h DE_12h-KLF13_MA0657.2 17 bp overlap
KLF14 1 dataset
Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap
KLF15 2 datasets
Motif DE_12h DE_12h-KLF15_MA1513.2 8 bp overlap
Motif DE_12h DE_12h-KLF15_MA1513.2 8 bp overlap
KLF17 2 datasets
Motif DE_12h DE_12h-KLF17_MA1514.2 14 bp overlap
Motif ES_0h ES_0h-KLF17_MA1514.2 14 bp overlap
KLF3 2 datasets
Motif DE_12h DE_12h-KLF3_MA1516.2 10 bp overlap
Motif DE_24h DE_24h-KLF3_MA1516.2 10 bp overlap
KLF5 1 dataset
ChIP ESO-26 GSE132680.KLF5.ESO-26 480 bp overlap
KLF7 1 dataset
Motif DE_12h DE_12h-KLF7_MA1959.2 8 bp overlap
MAF1 1 dataset
ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 179 bp overlap
MAFK 3 datasets
ChIP A549 ENCFF371EPR 381 bp overlap
ChIP HepG2 ENCFF743ZOF 241 bp overlap
ChIP HepG2 ENCFF767LDG 257 bp overlap
MYCN 2 datasets
ChIP 22Rv1_castrated GSE117304.MYCN.22Rv1_castrated 315 bp overlap
ChIP 22Rv1_intact GSE117304.MYCN.22Rv1_intact 298 bp overlap
MYOG 2 datasets
Motif DE_12h DE_12h-MYOG_MA0500.3 8 bp overlap
Motif ES_0h ES_0h-MYOG_MA0500.3 8 bp overlap
NFIB 2 datasets
Motif DE_12h DE_12h-NFIB_MA1643.2 17 bp overlap
Motif DE_24h DE_24h-NFIB_MA1643.2 17 bp overlap
NFYB 2 datasets
ChIP GM12878 ENCFF474DNH 299 bp overlap
ChIP HepG2 ENCFF174VYX 319 bp overlap
NHLH1 2 datasets
Motif DE_12h DE_12h-NHLH1_MA0048.3 9 bp overlap
Motif ES_0h ES_0h-NHLH1_MA0048.3 9 bp overlap
NHLH2 2 datasets
Motif DE_12h DE_12h-NHLH2_MA1529.2 16 bp overlap
Motif ES_0h ES_0h-NHLH2_MA1529.2 16 bp overlap
NR1I2 2 datasets
Motif DE_12h DE_12h-NR1I2_MA1533.2 15 bp overlap
Motif ES_0h ES_0h-NR1I2_MA1533.2 15 bp overlap
NR2F2 2 datasets
ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 605 bp overlap
ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 703 bp overlap
NRL 1 dataset
ChIP retina_Hu13 GSE137311.NRL.retina_Hu13 253 bp overlap
Neurod2 2 datasets
Motif DE_12h DE_12h-Neurod2_MA1993.2 6 bp overlap
Motif ES_0h ES_0h-Neurod2_MA1993.2 6 bp overlap
Nrf1 2 datasets
Motif DE_12h DE_12h-Nrf1_MA0506.3 12 bp overlap
Motif DE_24h DE_24h-Nrf1_MA0506.3 12 bp overlap
Olig2 2 datasets
Motif DE_12h DE_12h-Olig2_MA1997.2 6 bp overlap
Motif ES_0h ES_0h-Olig2_MA1997.2 6 bp overlap
PATZ1 5 datasets
Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap
Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap
Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap
Motif DE_48h DE_48h-PATZ1_MA1961.2 11 bp overlap
Motif ES_0h ES_0h-PATZ1_MA1961.2 11 bp overlap
POLR2A 2 datasets
ChIP body of pancreas ENCFF501FEC 637 bp overlap
ChIP body of pancreas ENCFF727UBE 437 bp overlap
POU5F1 3 datasets
ChIP DE_D1 DED1-OCT4_Batch_II 844 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 248 bp overlap
ChIP SKM-1 GSE93706.POU5F1.SKM-1 227 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 645 bp overlap
PRDM9 2 datasets
Motif DE_12h DE_12h-PRDM9_MA1723.2 20 bp overlap
Motif DE_24h DE_24h-PRDM9_MA1723.2 20 bp overlap
REST 2 datasets
Motif DE_12h DE_12h-REST_MA0138.3 20 bp overlap
Motif ES_0h ES_0h-REST_MA0138.3 20 bp overlap
RORC 2 datasets
ChIP HCC70 GSE126380.RORC.HCC70 680 bp overlap
ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 651 bp overlap
RUNX2 2 datasets
Motif DE_12h DE_12h-RUNX2_MA0511.2 9 bp overlap
Motif DE_24h DE_24h-RUNX2_MA0511.2 9 bp overlap
SIRT6 1 dataset
ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 425 bp overlap
SMARCA4 2 datasets
ChIP 22Rv1 GSE115615.SMARCA4.22Rv1 260 bp overlap
ChIP 22Rv1_PTEN-KO GSE115615.SMARCA4.22Rv1_PTEN-KO 356 bp overlap
SMARCC1 1 dataset
ChIP ESC S25-ESC-d0-BAF155-exp1 401 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 469 bp overlap
SP1 4 datasets
Motif DE_12h DE_12h-SP1_MA0079.5 9 bp overlap
Motif DE_12h DE_12h-SP1_MA0079.5 9 bp overlap
Motif DE_24h DE_24h-SP1_MA0079.5 9 bp overlap
Motif DE_48h DE_48h-SP1_MA0079.5 9 bp overlap
SP2 1 dataset
Motif DE_12h DE_12h-SP2_MA0516.3 9 bp overlap
SP4 2 datasets
Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap
Motif DE_24h DE_24h-SP4_MA0685.2 9 bp overlap
SP5 8 datasets
Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap
Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap
Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap
Motif DE_24h DE_24h-SP5_MA1965.2 6 bp overlap
Motif DE_24h DE_24h-SP5_MA1965.2 6 bp overlap
Motif DE_24h DE_24h-SP5_MA1965.2 6 bp overlap
Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap
Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap
SREBP2 2 datasets
ChIP HCC70 GSE126380.SREBP2.HCC70 586 bp overlap
ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 539 bp overlap
STAT3 1 dataset
ChIP WA01 ERP004237.STAT3.WA01 554 bp overlap
TBX20 2 datasets
Motif DE_12h DE_12h-TBX20_MA0689.1 11 bp overlap
Motif DE_24h DE_24h-TBX20_MA0689.1 11 bp overlap
TBX5 2 datasets
Motif DE_12h DE_12h-TBX5_MA0807.1 8 bp overlap
Motif DE_24h DE_24h-TBX5_MA0807.1 8 bp overlap
TCF7 1 dataset
ChIP breast-organoid_BRCA2-mut GSE113909.TCF7.breast-organoid_BRCA2-mut 360 bp overlap
TFAP2A 5 datasets
Motif DE_12h DE_12h-TFAP2A_MA0003.5 9 bp overlap
Motif DE_12h DE_12h-TFAP2A_MA0810.2 11 bp overlap
Motif DE_12h DE_12h-TFAP2A_MA0872.1 13 bp overlap
Motif DE_24h DE_24h-TFAP2A_MA0872.1 13 bp overlap
Motif ES_0h ES_0h-TFAP2A_MA0810.2 11 bp overlap
TFAP2B 5 datasets
Motif DE_12h DE_12h-TFAP2B_MA0811.2 11 bp overlap
Motif DE_12h DE_12h-TFAP2B_MA0812.2 9 bp overlap
Motif DE_12h DE_12h-TFAP2B_MA0813.1 13 bp overlap
Motif DE_24h DE_24h-TFAP2B_MA0813.1 13 bp overlap
Motif ES_0h ES_0h-TFAP2B_MA0811.2 11 bp overlap
TFAP2C 8 datasets
Motif DE_12h DE_12h-TFAP2C_MA0524.3 11 bp overlap
Motif DE_12h DE_12h-TFAP2C_MA0814.3 9 bp overlap
Motif DE_12h DE_12h-TFAP2C_MA0814.3 9 bp overlap
Motif DE_12h DE_12h-TFAP2C_MA0815.1 13 bp overlap
Motif DE_24h DE_24h-TFAP2C_MA0814.3 9 bp overlap
Motif DE_24h DE_24h-TFAP2C_MA0815.1 13 bp overlap
Motif ES_0h ES_0h-TFAP2C_MA0524.3 11 bp overlap
Motif ES_0h ES_0h-TFAP2C_MA0814.3 9 bp overlap
TFAP2E 1 dataset
Motif DE_12h DE_12h-TFAP2E_MA1569.2 9 bp overlap
TFAP4::FLI1 2 datasets
Motif DE_12h DE_12h-TFAP4FLI1_MA1967.2 14 bp overlap
Motif ES_0h ES_0h-TFAP4FLI1_MA1967.2 14 bp overlap
TFDP1 1 dataset
Motif DE_12h DE_12h-TFDP1_MA1122.2 8 bp overlap
TP63 1 dataset
ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 151 bp overlap
TRIM25 2 datasets
ChIP BT-549 GSE79588.TRIM25.BT-549 284 bp overlap
ChIP BT-549 GSE79588.TRIM25.BT-549 212 bp overlap
TRIM28 1 dataset
ChIP hESC GSE115387.TRIM28.hESC 242 bp overlap
Tbx6 2 datasets
Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap
Motif DE_24h DE_24h-Tbx6_MA1567.3 9 bp overlap
Tcf12 2 datasets
Motif DE_12h DE_12h-Tcf12_MA0521.3 6 bp overlap
Motif ES_0h ES_0h-Tcf12_MA0521.3 6 bp overlap
Tfcp2l1 1 dataset
Motif DE_12h DE_12h-Tfcp2l1_MA0145.2 14 bp overlap
Twist2 2 datasets
Motif DE_12h DE_12h-Twist2_MA0633.3 6 bp overlap
Motif ES_0h ES_0h-Twist2_MA0633.3 6 bp overlap
WDR5 1 dataset
ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 683 bp overlap
ZBED4 1 dataset
Motif DE_12h DE_12h-ZBED4_MA2328.1 10 bp overlap
ZBTB12 2 datasets
Motif DE_12h DE_12h-ZBTB12_MA1649.2 7 bp overlap
Motif DE_24h DE_24h-ZBTB12_MA1649.2 7 bp overlap
ZBTB33 4 datasets
ChIP HepG2 ENCFF778UKV 337 bp overlap
ChIP K-562 ENCSR876GXA.ZBTB33.K-562 76 bp overlap
ChIP K-562 ENCSR876GXA.ZBTB33.K-562 377 bp overlap
ChIP K562 ENCFF875HLX 57 bp overlap
ZBTB7A 1 dataset
ChIP VCaP_CSS GSE123089.ZBTB7A.VCaP_CSS 296 bp overlap
ZEB1 2 datasets
Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap
Motif DE_24h DE_24h-ZEB1_MA0103.4 6 bp overlap
ZFP14 2 datasets
Motif DE_12h DE_12h-ZFP14_MA1972.1 15 bp overlap
Motif ES_0h ES_0h-ZFP14_MA1972.1 15 bp overlap
ZFP57 1 dataset
ChIP hESC GSE115387.ZFP57.hESC 224 bp overlap
ZFX 1 dataset
ChIP HEK293T_22Rv1 GSE145160.ZFX.HEK293T_22Rv1 393 bp overlap
ZKSCAN3 1 dataset
Motif DE_12h DE_12h-ZKSCAN3_MA1973.2 14 bp overlap
ZNF148 5 datasets
Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap
Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap
Motif DE_24h DE_24h-ZNF148_MA1653.2 10 bp overlap
Motif DE_24h DE_24h-ZNF148_MA1653.2 10 bp overlap
Motif ES_0h ES_0h-ZNF148_MA1653.2 10 bp overlap
ZNF281 2 datasets
Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap
Motif DE_24h DE_24h-ZNF281_MA1630.3 10 bp overlap
ZNF316 1 dataset
ChIP K562 ENCFF838QCD 129 bp overlap
ZNF354C 2 datasets
Motif DE_12h DE_12h-ZNF354C_MA0130.1 6 bp overlap
Motif ES_0h ES_0h-ZNF354C_MA0130.1 6 bp overlap
ZNF454 3 datasets
Motif DE_12h DE_12h-ZNF454_MA1712.2 17 bp overlap
Motif DE_24h DE_24h-ZNF454_MA1712.2 17 bp overlap
Motif ES_0h ES_0h-ZNF454_MA1712.2 17 bp overlap
ZNF460 5 datasets
Motif DE_12h DE_12h-ZNF460_MA1596.1 16 bp overlap
Motif DE_12h DE_12h-ZNF460_MA1596.1 16 bp overlap
Motif DE_24h DE_24h-ZNF460_MA1596.1 16 bp overlap
Motif DE_48h DE_48h-ZNF460_MA1596.1 16 bp overlap
Motif ES_0h ES_0h-ZNF460_MA1596.1 16 bp overlap
ZNF530 2 datasets
Motif DE_12h DE_12h-ZNF530_MA1981.2 14 bp overlap
Motif DE_24h DE_24h-ZNF530_MA1981.2 14 bp overlap
ZNF549 1 dataset
Motif DE_12h DE_12h-ZNF549_MA1728.2 8 bp overlap
ZNF610 1 dataset
Motif DE_12h DE_12h-ZNF610_MA1713.2 10 bp overlap
ZNF669 2 datasets
Motif DE_12h DE_12h-ZNF669_MA1985.1 15 bp overlap
Motif DE_48h DE_48h-ZNF669_MA1985.1 15 bp overlap
ZNF682 1 dataset
Motif DE_12h DE_12h-ZNF682_MA1599.2 11 bp overlap
ZNF701 1 dataset
Motif DE_12h DE_12h-ZNF701_MA1987.2 17 bp overlap
ZNF707 2 datasets
Motif DE_12h DE_12h-ZNF707_MA1715.1 15 bp overlap
Motif DE_24h DE_24h-ZNF707_MA1715.1 15 bp overlap
ZNF76 3 datasets
Motif DE_12h DE_12h-ZNF76_MA1716.2 17 bp overlap
Motif DE_24h DE_24h-ZNF76_MA1716.2 17 bp overlap
Motif ES_0h ES_0h-ZNF76_MA1716.2 17 bp overlap
ZNF93 2 datasets
Motif DE_12h DE_12h-ZNF93_MA1721.2 14 bp overlap
Motif ES_0h ES_0h-ZNF93_MA1721.2 14 bp overlap
Zfx 2 datasets
Motif DE_12h DE_12h-Zfx_MA0146.3 10 bp overlap
Motif DE_24h DE_24h-Zfx_MA0146.3 10 bp overlap
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