chr2:44,932,798–44,933,373

chr2 : 44,932,798 – 44,933,373

575 bp 62 TFs 8 linked genes

This 575 bp open chromatin element is linked to 8 target genes and is bound by 62 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000276229		1.9 kb	Proximal	Proximity
ENSG00000277809		2.2 kb	Proximal	Proximity
LINC01833		2.4 kb	Proximal	Proximity
ENSG00000276048		4.1 kb	Proximal	Proximity
ENSG00000278957		4.4 kb	Proximal	Proximity
ENSG00000274547		5.5 kb	Proximal	Proximity
SIX3-AS1		8.1 kb	Proximal	Proximity
SIX3		8.3 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

62 transcription factors

ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 264 bp overlap

ChIP HCT-116 GSE103894.APC.HCT-116 317 bp overlap

ASH2L 1 dataset

ChIP H1 ENCFF399KAM 507 bp overlap

Ahr::Arnt 2 datasets

Motif DE_12h DE_12h-AhrArnt_MA0006.2 5 bp overlap

Motif DE_24h DE_24h-AhrArnt_MA0006.2 5 bp overlap

BRD4 4 datasets

ChIP CLL_patient4 GSE109411.BRD4.CLL_patient4 99 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 552 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 64 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 437 bp overlap

ChIP hMSC GSE117084.CBX4.hMSC 50 bp overlap

ChIP WA01 ENCSR000AQK.CHD1.WA01 284 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 305 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF262VBH 246 bp overlap

ChIP BLaER1 ENCFF335XTP 251 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 257 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 575 bp overlap

ESR1 17 datasets

ChIP MCF-7 GSE45822.ESR1.MCF-7 172 bp overlap

ChIP MCF-7_4OH-Tam GSE117941.ESR1.MCF-7_4OH-Tam 310 bp overlap

ChIP MCF-7_ARID1A-KO_4-OHT GSE123284.ESR1.MCF-7_ARID1A-KO_4-OHT 164 bp overlap

ChIP MCF-7_ARID1A-KO_clone14 GSE123284.ESR1.MCF-7_ARID1A-KO_clone14 154 bp overlap

ChIP MCF-7_D538G GSE148277.ESR1.MCF-7_D538G 352 bp overlap

ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 103 bp overlap

ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 226 bp overlap

ChIP MCF-7_IL1b_45m GSE67295.ESR1.MCF-7_IL1b_45m 204 bp overlap

ChIP MCF-7_LY2_ETOH GSE54592.ESR1.MCF-7_LY2_ETOH 186 bp overlap

ChIP MCF-7_RAD001 GSE103023.ESR1.MCF-7_RAD001 211 bp overlap

ChIP MCF-7_SHCTR_E2_TNF GSE59530.ESR1.MCF-7_SHCTR_E2_TNF 171 bp overlap

ChIP MCF-7_TNFa_45m GSE67295.ESR1.MCF-7_TNFa_45m 273 bp overlap

ChIP MCF-7_TamR GSE128445.ESR1.MCF-7_TamR 219 bp overlap

ChIP MCF-7_jc5850 GSE126004.ESR1.MCF-7_jc5850 213 bp overlap

ChIP MCF-7_jc5856 GSE126004.ESR1.MCF-7_jc5856 235 bp overlap

ChIP U2OS_10nM-E2-B GSE151039.ESR1.U2OS_10nM-E2-B 220 bp overlap

ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 292 bp overlap

EZH2 23 datasets

ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 349 bp overlap

ChIP A673 ENCFF955JRZ 88 bp overlap

ChIP B-cell ENCSR000AUZ.EZH2.B-cell 378 bp overlap

ChIP GM23248 ENCFF506FWX 330 bp overlap

ChIP GM23248 ENCFF506FWX 72 bp overlap

ChIP GM23338 ENCFF613YON 72 bp overlap

ChIP GM23338 ENCFF613YON 340 bp overlap

ChIP H1 ENCFF232NZA 575 bp overlap

ChIP Hep-G2 ENCSR000ARI.EZH2.Hep-G2 239 bp overlap

ChIP astrocyte ENCFF365JTP 215 bp overlap

ChIP astrocyte ENCFF365JTP 536 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 286 bp overlap

ChIP fibroblast of lung ENCFF479BAW 174 bp overlap

ChIP fibroblast of lung ENCFF479BAW 193 bp overlap

ChIP hepatocyte ENCFF552DZB 456 bp overlap

ChIP mammary epithelial cell ENCFF224GAI 89 bp overlap

ChIP neural progenitor cell ENCFF018MKA 295 bp overlap

ChIP neural progenitor cell ENCFF018MKA 560 bp overlap

ChIP neural progenitor cell ENCFF018MKA 575 bp overlap

ChIP neural progenitor cell ENCFF472NFV 575 bp overlap

ChIP neural progenitor cell ENCFF472NFV 178 bp overlap

ChIP neural progenitor cell ENCFF472NFV 172 bp overlap

ChIP peripheral-blood-mononuclear-cell_B-cell GSE115772.EZH2.peripheral-blood-mononuclear-cell_B-cell 110 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neural_progenitor ENCSR656MXA.EZH2_phosphoT487.neural_progenitor 465 bp overlap

GATA6 1 dataset

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 181 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 225 bp overlap

HIVEP1 1 dataset

ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 431 bp overlap

HNRNPLL 1 dataset

ChIP Hep-G2 ENCSR804HMZ.HNRNPLL.Hep-G2 290 bp overlap

ChIP T-cell GSE136853.IRF4.T-cell 64 bp overlap

JARID2 4 datasets

ChIP AMIPS6 GSE48516.JARID2.AMIPS6 173 bp overlap

ChIP AMIPS6 GSE48516.JARID2.AMIPS6 311 bp overlap

ChIP MRC-5_IPS25 GSE48516.JARID2.MRC-5_IPS25 246 bp overlap

ChIP UTEIPS11 GSE48516.JARID2.UTEIPS11 324 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 82 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 356 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 159 bp overlap

KDM4A 3 datasets

ChIP H1 ENCFF078LED 569 bp overlap

ChIP H1 ENCFF078LED 506 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 575 bp overlap

ChIP K562 ENCFF524IJO 366 bp overlap

ChIP WTC11 ENCFF223QFY 84 bp overlap

ChIP WTC11 ENCFF223QFY 407 bp overlap

Motif DE_12h DE_12h-MAZ_MA1522.2 8 bp overlap

Motif DE_24h DE_24h-MAZ_MA1522.2 8 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 418 bp overlap

ChIP neural ENCSR934NHU.MXI1.neural 282 bp overlap

MYOCD 1 dataset

ChIP A-549 GSE128921.MYOCD.A-549 431 bp overlap

NRIP1 1 dataset

ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 187 bp overlap

NUTM1 1 dataset

ChIP embryonic-kidney_induced GSE133122.NUTM1.embryonic-kidney_induced 258 bp overlap

PATZ1 2 datasets

Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap

Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap

PCBP1 2 datasets

ChIP Hep-G2 GSE120104.PCBP1.Hep-G2 229 bp overlap

ChIP Hep-G2 ENCSR872EVQ.PCBP1.Hep-G2 212 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 575 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 350 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 575 bp overlap

Plagl1 2 datasets

Motif DE_12h DE_12h-Plagl1_MA1615.2 8 bp overlap

Motif DE_24h DE_24h-Plagl1_MA1615.2 8 bp overlap

ChIP U-937_ATRA-treated_RAR GSE98006.RARA.U-937_ATRA-treated_RAR 389 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 373 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 411 bp overlap

RNF2 5 datasets

ChIP H1 ENCFF239FFS 104 bp overlap

ChIP H1 ENCFF239FFS 204 bp overlap

ChIP NCCIT GSE71675.RNF2.NCCIT 275 bp overlap

ChIP fibroblast GSE139053.RNF2.fibroblast 180 bp overlap

ChIP fibroblast GSE139053.RNF2.fibroblast 100 bp overlap

SAP30 1 dataset

ChIP WA01 ENCSR000ATR.SAP30.WA01 188 bp overlap

SIN3A 1 dataset

ChIP WA01 ENCSR000EBO.SIN3A.WA01 173 bp overlap

SMAD2-3 4 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 550 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 202 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 288 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 279 bp overlap

SMAD2_3 2 datasets

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 315 bp overlap

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 466 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 184 bp overlap

ChIP HCC70 GSE126380.SREBP2.HCC70 201 bp overlap

ChIP Aska-SS GSE108025.SS18.Aska-SS 575 bp overlap

STAT1 1 dataset

ChIP CD14_LPS GSE43036.STAT1.CD14_LPS 122 bp overlap

SUZ12 3 datasets

ChIP H1 ENCFF881NFR 575 bp overlap

ChIP NCCIT GSE71675.SUZ12.NCCIT 506 bp overlap

ChIP NT2/D1 ENCFF574SXS 69 bp overlap

TAF15 1 dataset

ChIP Hep-G2 ENCSR825MZS.TAF15.Hep-G2 216 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 143 bp overlap

TFAP2B 1 dataset

ChIP SK-N-SH ENCFF869XXQ 131 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 102 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 128 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 175 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 575 bp overlap

ZIC1 2 datasets

Motif DE_12h DE_12h-ZIC1_MA0696.1 14 bp overlap

Motif DE_24h DE_24h-ZIC1_MA0696.1 14 bp overlap

ZIC4 2 datasets

Motif DE_12h DE_12h-ZIC4_MA0751.2 14 bp overlap

Motif DE_24h DE_24h-ZIC4_MA0751.2 14 bp overlap

ZIC5 2 datasets

Motif DE_12h DE_12h-ZIC5_MA1584.2 15 bp overlap

Motif DE_24h DE_24h-ZIC5_MA1584.2 15 bp overlap

ZNF135 2 datasets

Motif DE_12h DE_12h-ZNF135_MA1587.1 14 bp overlap

Motif DE_24h DE_24h-ZNF135_MA1587.1 14 bp overlap

ZNF148 2 datasets

Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap

Motif DE_24h DE_24h-ZNF148_MA1653.2 10 bp overlap

ZNF257 2 datasets

Motif DE_12h DE_12h-ZNF257_MA1710.2 10 bp overlap

Motif DE_24h DE_24h-ZNF257_MA1710.2 10 bp overlap

ZNF281 2 datasets

Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap

Motif DE_24h DE_24h-ZNF281_MA1630.3 10 bp overlap

ZNF331 1 dataset

ChIP HEK293 GSE76494.ZNF331.HEK293 171 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 317 bp overlap

Zic2 2 datasets

Motif DE_12h DE_12h-Zic2_MA1629.2 9 bp overlap

Motif DE_24h DE_24h-Zic2_MA1629.2 9 bp overlap