chr22:38,866,394–38,866,832

chr22 : 38,866,394 – 38,866,832

438 bp 76 TFs 15 linked genes

This 438 bp open chromatin element is linked to 15 target genes and is bound by 76 transcription factors.

Linked Genes

15 genes

Gene	Expression	Dist. to TSS	Distance	Link type
CBX6		5.4 kb	Proximal	Proximity
NPTXR		22.6 kb	Distal	Multiome
DNAL4		72.4 kb	Distal	Multiome
SUN2		72.4 kb	Distal	Multiome
APOBEC3C		147.7 kb	Distal	Multiome
APOBEC3D		154.5 kb	Distal	Multiome
GTPBP1		160.8 kb	Distal	Multiome
JOSD1		165.5 kb	Distal	Multiome
APOBEC3F		174.3 kb	Distal	Multiome
TOMM22		184.6 kb	Distal	Multiome
CBY1		209.9 kb	Distal	Multiome
FAM227A		210.3 kb	Distal	Multiome
APOBEC3G		210.7 kb	Distal	Multiome
CBX7		286.0 kb	Distal	Multiome
DMC1		296.4 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

76 transcription factors

ChIP K-562 ENCSR641BSL.AGO1.K-562 169 bp overlap

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 228 bp overlap

ChIP prostate_cancer-associated-fibroblasts GSE90772.AR.prostate_cancer-associated-fibroblasts 112 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 67 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 75 bp overlap

ChIP HCT-116 GSE130477.ATF1.HCT-116 94 bp overlap

BCOR 2 datasets

ChIP WA01 GSE104690.BCOR.WA01 438 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 162 bp overlap

BRD4 8 datasets

ChIP CLL_patient2_4h_CpG_BET GSE109411.BRD4.CLL_patient2_4h_CpG_BET 438 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 141 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 438 bp overlap

ChIP MDA-MB-157 ERP003925.BRD4.MDA-MB-157 313 bp overlap

ChIP MPNST_PDJQ GSE62499.BRD4.MPNST_PDJQ 136 bp overlap

ChIP T-47D ERP003925.BRD4.T-47D 283 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 438 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 379 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 197 bp overlap

CTCF 14 datasets

ChIP GM23338 ENCFF772DML 201 bp overlap

ChIP H1 ENCFF230QSV 165 bp overlap

ChIP T-47D_Y537S GSE148277.CTCF.T-47D_Y537S 180 bp overlap

ChIP T-47D_Y537S GSE148277.CTCF.T-47D_Y537S 64 bp overlap

ChIP WA01 ENCSR000DLK.CTCF.WA01 91 bp overlap

ChIP endodermal cell ENCFF471YCZ 228 bp overlap

ChIP epithelial_kidney ENCSR000DVH.CTCF.epithelial_kidney 207 bp overlap

ChIP esophagus_squamous-epithelium ENCSR838RUX.CTCF.esophagus_squamous-epithelium 91 bp overlap

ChIP neural progenitor cell ENCFF420RBO 323 bp overlap

ChIP neural_progenitor ENCSR125NBL.CTCF.neural_progenitor 187 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR619IUE.CTCF.neuron_bipolar_doxy_4d 257 bp overlap

ChIP spleen ENCFF653ONC 391 bp overlap

ChIP spleen ENCFF653ONC 344 bp overlap

ChIP spleen ENCFF954DQD 322 bp overlap

CTCFL 3 datasets

ChIP K-562 GSE70764.CTCFL.K-562 298 bp overlap

ChIP K-562 GSE70764.CTCFL.K-562 58 bp overlap

ChIP Kelly_resistant GSE103030.CTCFL.Kelly_resistant 123 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 78 bp overlap

DNMT3B 1 dataset

ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 137 bp overlap

EGR1 2 datasets

ChIP K-562 ENCSR000BNE.EGR1.K-562 196 bp overlap

ChIP K562 ENCFF006PJY 245 bp overlap

ChIP HEK293 ENCFF336LFH 213 bp overlap

ChIP ME-1 GSE46044.ELF1.ME-1 223 bp overlap

EPAS1 1 dataset

ChIP 501-mel GSE95280.EPAS1.501-mel 263 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 438 bp overlap

ChIP K-562 GSE23730.ERG.K-562 152 bp overlap

ChIP K-562_DOX GSE23730.ERG.K-562_DOX 184 bp overlap

ESR1 10 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 225 bp overlap

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 124 bp overlap

ChIP Ishikawa_E2 GSE132426.ESR1.Ishikawa_E2 172 bp overlap

ChIP Ishikawa_EnhiE2 GSE99905.ESR1.Ishikawa_EnhiE2 174 bp overlap

ChIP MCF-7 GSE148277.ESR1.MCF-7 130 bp overlap

ChIP MCF-7_Y537S_DMSO GSE148277.ESR1.MCF-7_Y537S_DMSO 179 bp overlap

ChIP MDA-MB-231_LQ_45min GSE95121.ESR1.MDA-MB-231_LQ_45min 222 bp overlap

ChIP U2OS_100nM-E2 GSE151039.ESR1.U2OS_100nM-E2 146 bp overlap

ChIP U2OS_10nM-E2-B GSE151039.ESR1.U2OS_10nM-E2-B 129 bp overlap

ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 81 bp overlap

GABPA 1 dataset

ChIP WA01 ENCSR000BIW.GABPA.WA01 204 bp overlap

GLIS2 1 dataset

ChIP HCT-116_5FU GSE125927.GLIS2.HCT-116_5FU 300 bp overlap

GTF2F1 2 datasets

ChIP K-562 GSE120104.GTF2F1.K-562 156 bp overlap

ChIP K-562 ENCSR377BLZ.GTF2F1.K-562 140 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000AVB.HDAC2.WA01 202 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 438 bp overlap

HIF1A 2 datasets

ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 82 bp overlap

ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 164 bp overlap

HNRNPK 3 datasets

ChIP Hep-G2 GSE120104.HNRNPK.Hep-G2 194 bp overlap

ChIP K-562 ENCSR014RCS.HNRNPK.K-562 260 bp overlap

ChIP K-562 GSE120104.HNRNPK.K-562 258 bp overlap

HNRNPL 2 datasets

ChIP Hep-G2 GSE120104.HNRNPL.Hep-G2 213 bp overlap

ChIP Hep-G2 ENCSR315JJE.HNRNPL.Hep-G2 198 bp overlap

IFNA1 1 dataset

ChIP Huh-7_GFP GSE110511.IFNA1.Huh-7_GFP 122 bp overlap

ChIP WA01 ENCSR000BKP.JUND.WA01 133 bp overlap

KDM5B 1 dataset

ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 139 bp overlap

KDM6B 1 dataset

ChIP CUTLL1 GSE56694.KDM6B.CUTLL1 55 bp overlap

ChIP GBM1A GSE62211.KLF9.GBM1A 224 bp overlap

ChIP HeLa GSE41006.MBD2.HeLa 105 bp overlap

MED1 2 datasets

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 132 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 120 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 144 bp overlap

MYOCD 1 dataset

ChIP A-549 GSE128921.MYOCD.A-549 357 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 137 bp overlap

NANOG 2 datasets

ChIP WA01 ERP004238.NANOG.WA01 203 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 248 bp overlap

NCAPH2 2 datasets

ChIP HEK293 GSE97540.NCAPH2.HEK293 438 bp overlap

ChIP IMR-90_FLAG_G GSE118494.NCAPH2.IMR-90_FLAG_G 438 bp overlap

OGG1 3 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 242 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 256 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 257 bp overlap

ChIP HCT-116_ab20662 GSE97527.PAF1.HCT-116_ab20662 116 bp overlap

PAX5 2 datasets

ChIP GM12892 ENCFF635MSF 70 bp overlap

ChIP NALM-6 GSE126300.PAX5.NALM-6 54 bp overlap

POLR2A 10 datasets

ChIP GM12891 ENCFF379FCI 404 bp overlap

ChIP GM12892 ENCFF245LYF 217 bp overlap

ChIP GM18526 ENCFF599EPS 202 bp overlap

ChIP GM23338 ENCFF450WCS 337 bp overlap

ChIP HL-60 ENCFF321XKE 247 bp overlap

ChIP esophagus muscularis mucosa ENCFF432ZCY 223 bp overlap

ChIP spleen ENCFF044PYR 252 bp overlap

ChIP spleen ENCFF446ZGT 317 bp overlap

ChIP spleen ENCFF446ZGT 142 bp overlap

ChIP spleen ENCFF706IUS 438 bp overlap

POLR2G 2 datasets

ChIP K562 ENCFF047BLG 382 bp overlap

ChIP K562 ENCFF648YPL 382 bp overlap

POU5F1 4 datasets

ChIP BJ1-hTERT GSE92491.POU5F1.BJ1-hTERT 52 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 438 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 250 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 69 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 438 bp overlap

PRPF4 2 datasets

ChIP K-562 GSE120104.PRPF4.K-562 74 bp overlap

ChIP K-562 ENCSR220YXI.PRPF4.K-562 68 bp overlap

ChIP TSU-1621MT GSE60477.RARA.TSU-1621MT 152 bp overlap

RBFOX2 6 datasets

ChIP HepG2 ENCFF554DMZ 301 bp overlap

ChIP HepG2 ENCFF554DMZ 76 bp overlap

ChIP HepG2 ENCFF939HTZ 76 bp overlap

ChIP K562 ENCFF196WTG 401 bp overlap

ChIP K562 ENCFF967GRF 401 bp overlap

ChIP K562 ENCFF967GRF 164 bp overlap

RBM22 3 datasets

ChIP K-562 GSE120104.RBM22.K-562 186 bp overlap

ChIP K-562 ENCSR848AOP.RBM22.K-562 172 bp overlap

ChIP K-562 GSE120104.RBM22.K-562 69 bp overlap

RBM39 3 datasets

ChIP Hep-G2 ENCSR339JTP.RBM39.Hep-G2 118 bp overlap

ChIP Hep-G2 GSE120104.RBM39.Hep-G2 138 bp overlap

ChIP HepG2 ENCFF084YZE 50 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 119 bp overlap

REST 2 datasets

ChIP hiPSC_IA12 GSE106870.REST.hiPSC_IA12 157 bp overlap

ChIP hiPSC_IB12 GSE106870.REST.hiPSC_IB12 165 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 438 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 438 bp overlap

RUNX1 1 dataset

ChIP SKNO-1 GSE23730.RUNX1.SKNO-1 151 bp overlap

SMAD5 1 dataset

ChIP K-562 ENCSR000FCD.SMAD5.K-562 96 bp overlap

SMC1 3 datasets

ChIP DKO GSE131606.SMC1.DKO 260 bp overlap

ChIP DKO GSE131606.SMC1.DKO 88 bp overlap

ChIP IMR-90_OIS GSE118494.SMC1.IMR-90_OIS 137 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 213 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 173 bp overlap

ChIP ME-1 GSE46044.SPI1.ME-1 231 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 438 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 438 bp overlap

SSRP1 1 dataset

ChIP HT-1080_AclacinomycinA GSE107595.SSRP1.HT-1080_AclacinomycinA 166 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 438 bp overlap

SUPT5H 3 datasets

ChIP DLD-1_NELFCD-AID_treated GSE144786.SUPT5H.DLD-1_NELFCD-AID_treated 174 bp overlap

ChIP HCT-116_pThr806 GSE138548.SUPT5H.HCT-116_pThr806 171 bp overlap

ChIP HCT-116_pThr806 GSE138548.SUPT5H.HCT-116_pThr806 150 bp overlap

TAF15 1 dataset

ChIP HepG2 ENCFF116QSW 60 bp overlap

ChIP ME-1 GSE46044.TAL1.ME-1 438 bp overlap

TCF12 1 dataset

ChIP ME-1 GSE46044.TCF12.ME-1 209 bp overlap

ChIP GM12878 ENCSR000BQT.TCF3.GM12878 177 bp overlap

ChIP breast-organoid_BRCA2-mut GSE113909.TCF7.breast-organoid_BRCA2-mut 283 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 230 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 438 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 236 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 438 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 438 bp overlap

ZBTB33 4 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 438 bp overlap

ChIP K562 ENCFF427SDV 365 bp overlap

ChIP K562 ENCFF427SDV 221 bp overlap

ChIP K562 ENCFF875HLX 187 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 372 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 438 bp overlap

ZNF711 1 dataset

ChIP HEK293T GSE145160.ZNF711.HEK293T 59 bp overlap

ZNF90 1 dataset

ChIP HEK293T GSE78099.ZNF90.HEK293T 137 bp overlap