chr20:3,875,544–3,876,019

chr20 : 3,875,544 – 3,876,019

475 bp 80 TFs 6 linked genes

This 475 bp open chromatin element is linked to 6 target genes and is bound by 80 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
PANK2-AS1		13.3 kb	Distal	Multiome
PANK2		13.5 kb	Distal	Multiome
MAVS		29.1 kb	Distal	Multiome
CDC25B		79.6 kb	Distal	Multiome
ADISSP		108.1 kb	Distal	Multiome
RNF24		139.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

80 transcription factors

AGO2 3 datasets

ChIP HepG2 ENCFF252VFI 384 bp overlap

ChIP HepG2 ENCFF252VFI 167 bp overlap

ChIP HepG2 ENCFF773YDL 167 bp overlap

ChIP MCF-7 GSE48930.AR.MCF-7 152 bp overlap

ARID2 4 datasets

ChIP Aska-SS GSE108025.ARID2.Aska-SS 295 bp overlap

ChIP Aska-SS_shSSX GSE108025.ARID2.Aska-SS_shSSX 270 bp overlap

ChIP Aska-SS_shSSX GSE108025.ARID2.Aska-SS_shSSX 101 bp overlap

ChIP BIN-67_lentivirus-SMARCA4 GSE117734.ARID2.BIN-67_lentivirus-SMARCA4 466 bp overlap

ChIP A-549 ENCSR000BQH.BCL3.A-549 195 bp overlap

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 197 bp overlap

BRD4 5 datasets

ChIP K-562_iBET-IFNG GSE138084.BRD4.K-562_iBET-IFNG 152 bp overlap

ChIP cortical-interneuron_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_KCl-pos_JQ1-neg 189 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 358 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-pos GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-pos 336 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 236 bp overlap

CDKN1B 1 dataset

ChIP MDA-MB-231_p27CK-DD GSE112444.CDKN1B.MDA-MB-231_p27CK-DD 230 bp overlap

ChIP Caco-2_DIFF GSE23436.CDX2.Caco-2_DIFF 114 bp overlap

CTCF 3 datasets

ChIP HL-60 ERP008568.CTCF.HL-60 226 bp overlap

ChIP U-937 ERP008568.CTCF.U-937 224 bp overlap

ChIP anterior-temporal-cortex_fetal GSE116825.CTCF.anterior-temporal-cortex_fetal 154 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 283 bp overlap

ChIP SCCOHT-1 GSE117734.DPF2.SCCOHT-1 190 bp overlap

ChIP ProEs GSE59087.EED.ProEs 178 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 144 bp overlap

EP300 1 dataset

ChIP AML GSE131939.EP300.AML 161 bp overlap

ChIP ME-1 GSE46044.ERG.ME-1 264 bp overlap

ChIP SKNO-1 GSE23730.ERG.SKNO-1 300 bp overlap

ChIP TSU-1621MT GSE60477.ERG.TSU-1621MT 305 bp overlap

ChIP TSU-1621MT_ATRA GSE60477.ERG.TSU-1621MT_ATRA 191 bp overlap

ChIP VCaP GSE49091.ERG.VCaP 121 bp overlap

ESR1_pS118 1 dataset

ChIP MCF-7_Veh_sc GSE117569.ESR1_pS118.MCF-7_Veh_sc 289 bp overlap

ESRRA 1 dataset

ChIP SK-BR-3_HRG GSE81651.ESRRA.SK-BR-3_HRG 343 bp overlap

ESRRG 1 dataset

ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 431 bp overlap

ETS1 2 datasets

ChIP CTV-1_DSG GSE128835.ETS1.CTV-1_DSG 184 bp overlap

ChIP HUVEC-C_VEGF_4H GSE41166.ETS1.HUVEC-C_VEGF_4H 173 bp overlap

FIP1L1 1 dataset

ChIP Hep-G2 ENCSR313VZG.FIP1L1.Hep-G2 198 bp overlap

FLI1 3 datasets

ChIP CTV-1_DSG GSE128835.FLI1.CTV-1_DSG 133 bp overlap

ChIP SKNO-1 GSE23730.FLI1.SKNO-1 313 bp overlap

ChIP UAE_ZINC GSE23730.FLI1.UAE_ZINC 160 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-2 196 bp overlap

ChIP PC-3_GSK GSE148982.FOXA2.PC-3_GSK 119 bp overlap

FOXO3 1 dataset

ChIP Hep-G2 GSE97661.FOXO3.Hep-G2 120 bp overlap

GATA2 1 dataset

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 285 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 259 bp overlap

ChIP DE DE-GATA4-2 371 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 303 bp overlap

ChIP DE DE-GATA6-2 307 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 291 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 276 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 356 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 347 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 340 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 356 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 363 bp overlap

GFI1B 1 dataset

ChIP K-562 ENCSR509GDT.GFI1B.K-562 116 bp overlap

HIVEP1 1 dataset

ChIP HepG2 ENCFF063BCC 304 bp overlap

HNRNPH1 2 datasets

ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 262 bp overlap

ChIP Hep-G2 GSE120104.HNRNPH1.Hep-G2 251 bp overlap

IFNA1 2 datasets

ChIP Huh-7_GFP GSE110511.IFNA1.Huh-7_GFP 224 bp overlap

ChIP Huh-7_NS5 GSE110511.IFNA1.Huh-7_NS5 460 bp overlap

JMJD1C 1 dataset

ChIP HL-60 GSE63484.JMJD1C.HL-60 81 bp overlap

ChIP MDA-BoM-1833 GSE112444.JUN.MDA-BoM-1833 175 bp overlap

KDM1A 1 dataset

ChIP Kasumi-1_DMSO GSE71739.KDM1A.Kasumi-1_DMSO 273 bp overlap

KDM5B 1 dataset

ChIP HepG2 ENCFF706LUI 427 bp overlap

ChIP Kasumi-1_siRE GSE121280.LDB1.Kasumi-1_siRE 207 bp overlap

LMO2 2 datasets

ChIP Kasumi-1_SIRUNX1ETO GSE60130.LMO2.Kasumi-1_SIRUNX1ETO 300 bp overlap

ChIP TSU-1621MT GSE60477.LMO2.TSU-1621MT 189 bp overlap

ChIP HepG2 ENCFF900ZJD 361 bp overlap

MYBL2 3 datasets

ChIP A-673 GSE119971.MYBL2.A-673 129 bp overlap

ChIP MCF-10A_DOX GSE115787.MYBL2.MCF-10A_DOX 229 bp overlap

ChIP MCF-10A_ctrl GSE115787.MYBL2.MCF-10A_ctrl 213 bp overlap

ChIP CC-LP-1 GSE124430.MYC.CC-LP-1 135 bp overlap

ChIP MCF-7 ENCSR000DMQ.MYC.MCF-7 129 bp overlap

NCAPH2 1 dataset

ChIP IMR-90_FLAG_OIS GSE118494.NCAPH2.IMR-90_FLAG_OIS 335 bp overlap

NFATC1 1 dataset

ChIP GM12878 ENCSR000BQL.NFATC1.GM12878 431 bp overlap

NOTCH1 1 dataset

ChIP pulmonary-artery_endothelial-cell_siPFKFB3 GSE89786.NOTCH1.pulmonary-artery_endothelial-cell_siPFKFB3 266 bp overlap

NR1H2 1 dataset

ChIP HT29_GW3965_48H GSE77039.NR1H2.HT29_GW3965_48H 150 bp overlap

NR3C1 1 dataset

ChIP A-549 ENCSR000BJR.NR3C1.A-549 131 bp overlap

PCBP2 2 datasets

ChIP Hep-G2 GSE120104.PCBP2.Hep-G2 207 bp overlap

ChIP Hep-G2 ENCSR945NSF.PCBP2.Hep-G2 212 bp overlap

ChIP MCF-7_R5020 GSE68355.PGR.MCF-7_R5020 222 bp overlap

POLR2A 17 datasets

ChIP A549 ENCFF034EBG 416 bp overlap

ChIP GM12878 ENCFF631ERR 288 bp overlap

ChIP GM12878 ENCFF631ERR 475 bp overlap

ChIP GM18505 ENCFF311CYB 431 bp overlap

ChIP GM18505 ENCFF311CYB 344 bp overlap

ChIP H1 ENCFF833NJP 234 bp overlap

ChIP HepG2 ENCFF718XAJ 407 bp overlap

ChIP HepG2 ENCFF736SLT 339 bp overlap

ChIP K562 ENCFF137JSF 443 bp overlap

ChIP endothelial cell of umbilical vein ENCFF467WJF 306 bp overlap

ChIP erythroblast ENCFF498VMR 475 bp overlap

ChIP esophagus muscularis mucosa ENCFF432ZCY 367 bp overlap

ChIP esophagus muscularis mucosa ENCFF791ZXN 332 bp overlap

ChIP spleen ENCFF044PYR 373 bp overlap

ChIP spleen ENCFF446ZGT 371 bp overlap

ChIP stomach ENCFF820WZN 345 bp overlap

ChIP upper lobe of left lung ENCFF640VPA 475 bp overlap

POLR2G 2 datasets

ChIP HepG2 ENCFF241AEG 423 bp overlap

ChIP HepG2 ENCFF508UTS 419 bp overlap

POU2F2 1 dataset

ChIP HNPC_UNDIF GSE74814.POU2F2.HNPC_UNDIF 221 bp overlap

POU4F2 1 dataset

ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 175 bp overlap

RBM22 3 datasets

ChIP HepG2 ENCFF292RVQ 364 bp overlap

ChIP HepG2 ENCFF292RVQ 157 bp overlap

ChIP HepG2 ENCFF561IAJ 365 bp overlap

RPA2_phospho 1 dataset

ChIP HeLa GSE108172.RPA2_phospho.HeLa 287 bp overlap

RUNX1 3 datasets

ChIP 697 GSE138031.RUNX1.697 72 bp overlap

ChIP Kasumi-1 GSE45738.RUNX1.Kasumi-1 199 bp overlap

ChIP SKNO-1 GSE23730.RUNX1.SKNO-1 195 bp overlap

RUNX1T1 2 datasets

ChIP Kasumi-1 GSE102697.RUNX1T1.Kasumi-1 167 bp overlap

ChIP Kasumi-1_E2 GSE102697.RUNX1T1.Kasumi-1_E2 167 bp overlap

SMAD2-3 2 datasets

ChIP HGrC1_WT GSE138496.SMAD2-3.HGrC1_WT 56 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 288 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 402 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 266 bp overlap

SMAD3 4 datasets

ChIP H69_4TGF GSE145250.SMAD3.H69_4TGF 101 bp overlap

ChIP H69_4TGF GSE145250.SMAD3.H69_4TGF 166 bp overlap

ChIP H69_5Veh GSE145250.SMAD3.H69_5Veh 288 bp overlap

ChIP breast-cancer_triple-negative GSE130364.SMAD3.breast-cancer_triple-negative 412 bp overlap

SMARCA4 2 datasets

ChIP CTV-1_DSG GSE128835.SMARCA4.CTV-1_DSG 173 bp overlap

ChIP CTV-1_FLAG GSE128835.SMARCA4.CTV-1_FLAG 205 bp overlap

SPI1 20 datasets

ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 352 bp overlap

ChIP CTV-1_delQ GSE128835.SPI1.CTV-1_delQ 216 bp overlap

ChIP CTV-1_delQA GSE128835.SPI1.CTV-1_delQA 182 bp overlap

ChIP DC_96h_donorM GSE128834.SPI1.DC_96h_donorM 220 bp overlap

ChIP EM-3 GSE128834.SPI1.EM-3 196 bp overlap

ChIP HL-60 ENCFF645GBT 171 bp overlap

ChIP K-562 ENCSR000BGW.SPI1.K-562 118 bp overlap

ChIP KG-1 GSE128834.SPI1.KG-1 164 bp overlap

ChIP Kasumi-1_SICTR GSE60130.SPI1.Kasumi-1_SICTR 239 bp overlap

ChIP Kasumi-1_SIRUNX1ETO GSE60130.SPI1.Kasumi-1_SIRUNX1ETO 228 bp overlap

ChIP NB4 GSE128834.SPI1.NB4 226 bp overlap

ChIP THP-1 GSE128834.SPI1.THP-1 111 bp overlap

ChIP U-937 GSE128834.SPI1.U-937 192 bp overlap

ChIP monocyte GSE31621.SPI1.monocyte 126 bp overlap

ChIP primary-monocyte_18h_donorO GSE128834.SPI1.primary-monocyte_18h_donorO 177 bp overlap

ChIP primary-monocyte_4h_donorO GSE128834.SPI1.primary-monocyte_4h_donorO 151 bp overlap

ChIP primary-monocyte_LPS-4h_donorO GSE128834.SPI1.primary-monocyte_LPS-4h_donorO 145 bp overlap

ChIP primary-monocyte_donorA_ncMO GSE128834.SPI1.primary-monocyte_donorA_ncMO 121 bp overlap

ChIP primary-neutrophil_donorE GSE128834.SPI1.primary-neutrophil_donorE 91 bp overlap

ChIP primary-neutrophil_donorF GSE128834.SPI1.primary-neutrophil_donorF 152 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 248 bp overlap

STAT3 1 dataset

ChIP MCF-7_jc5848 GSE126004.STAT3.MCF-7_jc5848 236 bp overlap

SUPT16H 1 dataset

ChIP hiF-T GSE98758.SUPT16H.hiF-T 60 bp overlap

SUPT5H 3 datasets

ChIP DLD-1_NELFCD-AID GSE144786.SUPT5H.DLD-1_NELFCD-AID 322 bp overlap

ChIP HCT-116_pThr806 GSE138548.SUPT5H.HCT-116_pThr806 458 bp overlap

ChIP HeLa GSE125534.SUPT5H.HeLa 319 bp overlap

SUPT6H 2 datasets

ChIP HCT-116 GSE130509.SUPT6H.HCT-116 475 bp overlap

ChIP HCT-116_Inhibitor GSE130509.SUPT6H.HCT-116_Inhibitor 382 bp overlap

ChIP TSU-1621MT GSE60477.TAL1.TSU-1621MT 150 bp overlap

TARDBP 1 dataset

ChIP K-562 GSE120104.TARDBP.K-562 185 bp overlap

TCF12 1 dataset

ChIP Kasumi-1 GSE23730.TCF12.Kasumi-1 217 bp overlap

ChIP K-562 ENCSR970OJY.TCF3.K-562 136 bp overlap

TEAD4 1 dataset

ChIP hMSC-TERT4 GSE140782.TEAD4.hMSC-TERT4 236 bp overlap

THAP1 1 dataset

ChIP K-562 ENCSR000BNN.THAP1.K-562 97 bp overlap

U2AF1 1 dataset

ChIP Hep-G2 GSE120104.U2AF1.Hep-G2 196 bp overlap

ChIP Huh-7 GSE97411.YY1.Huh-7 250 bp overlap

ZBTB16 1 dataset

ChIP KG-1_shEZH2 GSE109619.ZBTB16.KG-1_shEZH2 65 bp overlap

ZC3H13 1 dataset

ChIP HepG2 ENCFF444JZJ 330 bp overlap

ZNF143 2 datasets

ChIP FLP143HA_T0 GSE39263.ZNF143.FLP143HA_T0 155 bp overlap

ChIP FLP76_T4 GSE39263.ZNF143.FLP76_T4 155 bp overlap

ChIP K-562 ENCSR195QFV.ZNF3.K-562 189 bp overlap

ZNF398 1 dataset

ChIP H9 GSE133630.ZNF398.H9 154 bp overlap

ZNF776 2 datasets

ChIP HepG2 ENCFF009LSZ 344 bp overlap

ChIP HepG2 ENCFF009LSZ 475 bp overlap

ZNF891 1 dataset

ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 216 bp overlap

ZSCAN22 1 dataset

ChIP HEK293 GSE76494.ZSCAN22.HEK293 214 bp overlap