chr17 : 56,708,321 – 56,709,261
940 bp 92 TFs 4 linked genes
This 940 bp open chromatin element is linked to 4 target genes and is bound by 92 transcription factors.
Linked Genes
4 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
DGKE 125.3 kb Distal Multiome
TRIM25 205.2 kb Distal Multiome
COIL 252.2 kb Distal Multiome
SCPEP1 269.3 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr17:56,703,321 – 56,714,261
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
92 transcription factors
Source
Cell type
ARNT2 2 datasets
Motif DE_60h DE_60h-ARNT2_MA1464.2 8 bp overlap
Motif DE_72h DE_72h-ARNT2_MA1464.2 8 bp overlap
ARNT::HIF1A 2 datasets
Motif DE_60h DE_60h-ARNTHIF1A_MA0259.2 5 bp overlap
Motif DE_72h DE_72h-ARNTHIF1A_MA0259.2 5 bp overlap
Arnt 2 datasets
Motif DE_60h DE_60h-Arnt_MA0004.1 6 bp overlap
Motif DE_72h DE_72h-Arnt_MA0004.1 6 bp overlap
Arntl 2 datasets
Motif DE_60h DE_60h-Arntl_MA0603.2 8 bp overlap
Motif DE_72h DE_72h-Arntl_MA0603.2 8 bp overlap
BHLHE41 2 datasets
Motif DE_60h DE_60h-BHLHE41_MA0636.1 10 bp overlap
Motif DE_72h DE_72h-BHLHE41_MA0636.1 10 bp overlap
CREB3 2 datasets
Motif DE_60h DE_60h-CREB3_MA0638.2 12 bp overlap
Motif DE_72h DE_72h-CREB3_MA0638.2 12 bp overlap
CREB3L4 2 datasets
Motif DE_60h DE_60h-CREB3L4_MA1474.2 10 bp overlap
Motif DE_72h DE_72h-CREB3L4_MA1474.2 10 bp overlap
Creb3l2 2 datasets
Motif DE_60h DE_60h-Creb3l2_MA0608.1 9 bp overlap
Motif DE_72h DE_72h-Creb3l2_MA0608.1 9 bp overlap
Dmrt1 2 datasets
Motif DE_60h DE_60h-Dmrt1_MA1603.2 9 bp overlap
Motif DE_72h DE_72h-Dmrt1_MA1603.2 9 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 369 bp overlap
ERF::NHLH1 2 datasets
Motif DE_60h DE_60h-ERFNHLH1_MA1938.2 16 bp overlap
Motif DE_72h DE_72h-ERFNHLH1_MA1938.2 16 bp overlap
ESR1 1 dataset
ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 94 bp overlap
EZH2 2 datasets
ChIP DOHH2 ENCFF528GDC 102 bp overlap
ChIP RL_CPI169-10d GSE134136.EZH2.RL_CPI169-10d 189 bp overlap
FIGLA 2 datasets
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 771 bp overlap
ChIP DE DE-FOXA2-2 624 bp overlap
FOXH1 3 datasets
Motif DE_48h DE_48h-FOXH1_MA0479.2 8 bp overlap
Motif DE_60h DE_60h-FOXH1_MA0479.2 8 bp overlap
Motif DE_72h DE_72h-FOXH1_MA0479.2 8 bp overlap
GATA2 2 datasets
ChIP primary-endometrial-stromal-cell_Veh_P1 GSE145673.GATA2.primary-endometrial-stromal-cell_Veh_P1 104 bp overlap
ChIP primary-endometrial-stromal-cell_Veh_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_Veh_P2 90 bp overlap
GATA3_Nter 1 dataset
ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 56 bp overlap
GATA4 4 datasets
ChIP DE DE-GATA4-1 825 bp overlap
ChIP DE DE-GATA4-2 844 bp overlap
ChIP foregut GSE117136.GATA4.foregut 515 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 374 bp overlap
GATA6 13 datasets
ChIP DE DE-GATA6-1 828 bp overlap
ChIP DE DE-GATA6-2 820 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 555 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 626 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 555 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 718 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 662 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 625 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 690 bp overlap
ChIP foregut GSE117136.GATA6.foregut 552 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 366 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 264 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 284 bp overlap
Gli2 1 dataset
Motif DE_60h DE_60h-Gli2_MA0734.4 9 bp overlap
HES6 2 datasets
Motif DE_60h DE_60h-HES6_MA1493.1 10 bp overlap
Motif DE_72h DE_72h-HES6_MA1493.1 10 bp overlap
HIC2 3 datasets
Motif DE_48h DE_48h-HIC2_MA0738.2 6 bp overlap
Motif DE_60h DE_60h-HIC2_MA0738.2 6 bp overlap
Motif DE_72h DE_72h-HIC2_MA0738.2 6 bp overlap
HNRNPK 3 datasets
ChIP Hep-G2 GSE120104.HNRNPK.Hep-G2 96 bp overlap
ChIP HepG2 ENCFF493GNS 163 bp overlap
ChIP HepG2 ENCFF826MXP 160 bp overlap
HOXB13 2 datasets
Motif DE_60h DE_60h-HOXB13_MA0901.3 9 bp overlap
Motif DE_72h DE_72h-HOXB13_MA0901.3 9 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 507 bp overlap
KMT2C 1 dataset
ChIP BIN-67_lentivirus-SMARCA4 GSE117734.KMT2C.BIN-67_lentivirus-SMARCA4 193 bp overlap
MAX 2 datasets
Motif DE_60h DE_60h-MAX_MA0058.4 6 bp overlap
Motif DE_72h DE_72h-MAX_MA0058.4 6 bp overlap
MAX::MYC 2 datasets
Motif DE_60h DE_60h-MAXMYC_MA0059.2 10 bp overlap
Motif DE_72h DE_72h-MAXMYC_MA0059.2 10 bp overlap
MITF 5 datasets
ChIP 501-mel GSE61965.MITF.501-mel 182 bp overlap
ChIP 501-mel_20ng_K243R GSE137522.MITF.501-mel_20ng_K243R 264 bp overlap
ChIP 501-mel_K243Q GSE137522.MITF.501-mel_K243Q 364 bp overlap
Motif DE_60h DE_60h-MITF_MA0620.4 10 bp overlap
Motif DE_72h DE_72h-MITF_MA0620.4 10 bp overlap
MLX 2 datasets
Motif DE_60h DE_60h-MLX_MA0663.1 10 bp overlap
Motif DE_72h DE_72h-MLX_MA0663.1 10 bp overlap
MLXIPL 2 datasets
Motif DE_60h DE_60h-MLXIPL_MA0664.2 8 bp overlap
Motif DE_72h DE_72h-MLXIPL_MA0664.2 8 bp overlap
MNT 5 datasets
Motif DE_60h DE_60h-MNT_MA0825.2 6 bp overlap
Motif DE_72h DE_72h-MNT_MA0825.2 6 bp overlap
ChIP Hep-G2 ENCSR261EDU.MNT.Hep-G2 241 bp overlap
ChIP HepG2 ENCFF701PYP 226 bp overlap
ChIP MCF-7 ENCSR663ZZZ.MNT.MCF-7 186 bp overlap
MYC 3 datasets
ChIP CD34 GSE85488.MYC.CD34 113 bp overlap
Motif DE_60h DE_60h-MYC_MA0147.4 8 bp overlap
Motif DE_72h DE_72h-MYC_MA0147.4 8 bp overlap
MYCN 1 dataset
ChIP RH4 GSE83726.MYCN.RH4 164 bp overlap
MYOD1 1 dataset
ChIP RH30_DMSO GSE85169.MYOD1.RH30_DMSO 187 bp overlap
MYOG 1 dataset
ChIP RH4 GSE83726.MYOG.RH4 217 bp overlap
Mlxip 2 datasets
Motif DE_60h DE_60h-Mlxip_MA0622.2 6 bp overlap
Motif DE_72h DE_72h-Mlxip_MA0622.2 6 bp overlap
NR2C2 2 datasets
Motif DE_60h DE_60h-NR2C2_MA0504.2 14 bp overlap
Motif DE_72h DE_72h-NR2C2_MA0504.2 14 bp overlap
NR2F1 2 datasets
Motif DE_60h DE_60h-NR2F1_MA1537.2 13 bp overlap
Motif DE_72h DE_72h-NR2F1_MA1537.2 13 bp overlap
Nr2f6 2 datasets
Motif DE_60h DE_60h-Nr2f6_MA0677.2 13 bp overlap
Motif DE_72h DE_72h-Nr2f6_MA0677.2 13 bp overlap
PAX3 2 datasets
Motif DE_60h DE_60h-PAX3_MA0780.1 10 bp overlap
Motif DE_72h DE_72h-PAX3_MA0780.1 10 bp overlap
PCBP2 1 dataset
ChIP Hep-G2 GSE120104.PCBP2.Hep-G2 102 bp overlap
PLAG1 1 dataset
ChIP K-562 GSE111469.PLAG1.K-562 249 bp overlap
POU2F1::SOX2 2 datasets
Motif DE_60h DE_60h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_72h DE_72h-POU2F1SOX2_MA1962.1 17 bp overlap
POU3F1 2 datasets
Motif DE_60h DE_60h-POU3F1_MA0786.2 10 bp overlap
Motif DE_72h DE_72h-POU3F1_MA0786.2 10 bp overlap
POU3F2 2 datasets
Motif DE_60h DE_60h-POU3F2_MA0787.1 12 bp overlap
Motif DE_72h DE_72h-POU3F2_MA0787.1 12 bp overlap
POU3F4 2 datasets
Motif DE_60h DE_60h-POU3F4_MA0789.1 9 bp overlap
Motif DE_72h DE_72h-POU3F4_MA0789.1 9 bp overlap
PPARD 2 datasets
Motif DE_60h DE_60h-PPARD_MA1550.2 14 bp overlap
Motif DE_72h DE_72h-PPARD_MA1550.2 14 bp overlap
PRDM10 3 datasets
ChIP HEK293 ENCFF145WQQ 445 bp overlap
ChIP K-562 ENCSR120MPG.PRDM10.K-562 246 bp overlap
ChIP K562 ENCFF740YLK 111 bp overlap
Pax7 2 datasets
Motif DE_60h DE_60h-Pax7_MA0680.3 10 bp overlap
Motif DE_72h DE_72h-Pax7_MA0680.3 10 bp overlap
RARA 2 datasets
Motif DE_60h DE_60h-RARA_MA0729.1 18 bp overlap
Motif DE_72h DE_72h-RARA_MA0729.1 18 bp overlap
RREB1 3 datasets
Motif DE_48h DE_48h-RREB1_MA0073.2 19 bp overlap
Motif DE_60h DE_60h-RREB1_MA0073.2 19 bp overlap
Motif DE_72h DE_72h-RREB1_MA0073.2 19 bp overlap
RUNX1 1 dataset
ChIP NB4 GSE81992.RUNX1.NB4 217 bp overlap
RUVBL2 2 datasets
ChIP U2OS GSE130602.RUVBL2.U2OS 108 bp overlap
ChIP U2OS_cordycepin GSE130507.RUVBL2.U2OS_cordycepin 238 bp overlap
RXRB 2 datasets
Motif DE_60h DE_60h-RXRB_MA0855.1 14 bp overlap
Motif DE_72h DE_72h-RXRB_MA0855.1 14 bp overlap
RXRG 3 datasets
Motif DE_60h DE_60h-RXRG_MA0856.1 14 bp overlap
Motif DE_60h DE_60h-RXRG_MA1556.1 14 bp overlap
Motif DE_72h DE_72h-RXRG_MA0856.1 14 bp overlap
Rfx6 2 datasets
Motif DE_60h DE_60h-Rfx6_MA1724.2 9 bp overlap
Motif DE_72h DE_72h-Rfx6_MA1724.2 9 bp overlap
Rxra 2 datasets
Motif DE_60h DE_60h-Rxra_MA0512.2 14 bp overlap
Motif DE_72h DE_72h-Rxra_MA0512.2 14 bp overlap
SCRT1 2 datasets
Motif DE_60h DE_60h-SCRT1_MA0743.3 10 bp overlap
Motif DE_72h DE_72h-SCRT1_MA0743.3 10 bp overlap
SCRT2 2 datasets
Motif DE_60h DE_60h-SCRT2_MA0744.3 10 bp overlap
Motif DE_72h DE_72h-SCRT2_MA0744.3 10 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 291 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 816 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 661 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 499 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 469 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 606 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 410 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 729 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 550 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 301 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 372 bp overlap
SMARCA4 2 datasets
ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4 431 bp overlap
ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-T910M 155 bp overlap
SMARCC1 2 datasets
ChIP TTC-549_Dox GSE71504.SMARCC1.TTC-549_Dox 215 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 70 bp overlap
SOX10 2 datasets
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 409 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 697 bp overlap
SP5 4 datasets
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
SREBF2 2 datasets
Motif DE_60h DE_60h-SREBF2_MA0828.3 10 bp overlap
Motif DE_72h DE_72h-SREBF2_MA0828.3 10 bp overlap
Stat5b 2 datasets
Motif DE_60h DE_60h-Stat5b_MA1625.2 9 bp overlap
Motif DE_72h DE_72h-Stat5b_MA1625.2 9 bp overlap
TFAP4::ETV1 2 datasets
Motif DE_60h DE_60h-TFAP4ETV1_MA1966.2 13 bp overlap
Motif DE_72h DE_72h-TFAP4ETV1_MA1966.2 13 bp overlap
TFE3 2 datasets
Motif DE_60h DE_60h-TFE3_MA0831.3 10 bp overlap
Motif DE_72h DE_72h-TFE3_MA0831.3 10 bp overlap
TFEB 2 datasets
Motif DE_60h DE_60h-TFEB_MA0692.2 8 bp overlap
Motif DE_72h DE_72h-TFEB_MA0692.2 8 bp overlap
TFEC 2 datasets
Motif DE_60h DE_60h-TFEC_MA0871.3 8 bp overlap
Motif DE_72h DE_72h-TFEC_MA0871.3 8 bp overlap
THRB 2 datasets
Motif DE_60h DE_60h-THRB_MA1574.2 13 bp overlap
Motif DE_72h DE_72h-THRB_MA1574.2 13 bp overlap
USF1 7 datasets
Motif DE_60h DE_60h-USF1_MA0093.4 10 bp overlap
Motif DE_72h DE_72h-USF1_MA0093.4 10 bp overlap
ChIP H1 ENCFF090WVU 241 bp overlap
ChIP Hep-G2 ENCSR000BGM.USF1.Hep-G2 164 bp overlap
ChIP HepG2 ENCFF807KYJ 201 bp overlap
ChIP WA01 ENCSR000BIU.USF1.WA01 213 bp overlap
ChIP WTC11 ENCFF699QGS 425 bp overlap
USF2 4 datasets
Motif DE_60h DE_60h-USF2_MA0526.5 10 bp overlap
Motif DE_72h DE_72h-USF2_MA0526.5 10 bp overlap
ChIP Hep-G2 GSE97661.USF2.Hep-G2 147 bp overlap
ChIP WTC11 ENCFF139JAW 417 bp overlap
VEZF1 4 datasets
Motif DE_48h DE_48h-VEZF1_MA1578.2 6 bp overlap
Motif DE_60h DE_60h-VEZF1_MA1578.2 6 bp overlap
Motif DE_60h DE_60h-VEZF1_MA1578.2 6 bp overlap
Motif DE_72h DE_72h-VEZF1_MA1578.2 6 bp overlap
Wt1 2 datasets
Motif DE_48h DE_48h-Wt1_MA1627.2 10 bp overlap
Motif DE_60h DE_60h-Wt1_MA1627.2 10 bp overlap
ZBTB24 2 datasets
Motif DE_60h DE_60h-ZBTB24_MA2330.1 10 bp overlap
Motif DE_72h DE_72h-ZBTB24_MA2330.1 10 bp overlap
ZEB1 2 datasets
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap
ZNF189 2 datasets
ChIP HEK293 ENCFF638TIB 86 bp overlap
ChIP HEK293 ENCSR163RYW.ZNF189.HEK293 153 bp overlap
ZNF354C 5 datasets
Motif DE_48h DE_48h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_60h DE_60h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_60h DE_60h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_72h DE_72h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_72h DE_72h-ZNF354C_MA0130.1 6 bp overlap
ZNF418 2 datasets
Motif DE_60h DE_60h-ZNF418_MA1980.1 15 bp overlap
Motif DE_72h DE_72h-ZNF418_MA1980.1 15 bp overlap
ZNF460 2 datasets
Motif DE_48h DE_48h-ZNF460_MA1596.1 16 bp overlap
Motif DE_60h DE_60h-ZNF460_MA1596.1 16 bp overlap
ZNF692 2 datasets
Motif DE_60h DE_60h-ZNF692_MA1986.2 8 bp overlap
Motif DE_72h DE_72h-ZNF692_MA1986.2 8 bp overlap
ZNF768 2 datasets
Motif DE_60h DE_60h-ZNF768_MA1731.2 9 bp overlap
Motif DE_72h DE_72h-ZNF768_MA1731.2 9 bp overlap
ZNF770 2 datasets
Motif DE_48h DE_48h-ZNF770_MA2099.1 8 bp overlap
Motif DE_60h DE_60h-ZNF770_MA2099.1 8 bp overlap
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