chr14 : 100,830,747 – 100,832,118
1,371 bp 99 TFs 4 linked genes
This 1.4 kb open chromatin element is linked to 4 target genes and is bound by 99 transcription factors.
Linked Genes
4 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
MEG3 at TSS At TSS Proximity
MIR493HG 4.2 kb Proximal Proximity
DLK1 103.9 kb Distal Multiome
ENSG00000230805 246.9 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr14:100,825,747 – 100,837,118
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
99 transcription factors
Source
Cell type
ARID1A 2 datasets
ChIP HAP1 GSE108387.ARID1A.HAP1 407 bp overlap
ChIP NGP GSE134626.ARID1A.NGP 233 bp overlap
ARID2 1 dataset
ChIP Aska-SS GSE108025.ARID2.Aska-SS 791 bp overlap
BRD4 11 datasets
ChIP BE2C GSE80151.BRD4.BE2C 227 bp overlap
ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 536 bp overlap
ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 177 bp overlap
ChIP SK-N-BE2-C GSE80151.BRD4.SK-N-BE2-C 227 bp overlap
ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 251 bp overlap
ChIP cortical-interneuron GSE117508.BRD4.cortical-interneuron 202 bp overlap
ChIP cortical-interneuron_KCl-pos GSE117508.BRD4.cortical-interneuron_KCl-pos 108 bp overlap
ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 395 bp overlap
ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 312 bp overlap
ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 1144 bp overlap
ChIP retina_AB1-FW23 GSE86981.BRD4.retina_AB1-FW23 298 bp overlap
CCAR2 1 dataset
ChIP Hep-G2 ENCSR247XFV.CCAR2.Hep-G2 156 bp overlap
CDX2 1 dataset
Motif DE_72h DE_72h-CDX2_MA0465.3 8 bp overlap
CHD7 1 dataset
ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 202 bp overlap
CTCF 2 datasets
Motif DE_72h DE_72h-CTCF_MA1929.2 31 bp overlap
ChIP HAP1_clone21_CTCF-CRISPR GSE152721.CTCF.HAP1_clone21_CTCF-CRISPR 305 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF031ISE 597 bp overlap
Crx 1 dataset
Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap
DPRX 1 dataset
Motif DE_72h DE_72h-DPRX_MA1480.2 9 bp overlap
DUX4 1 dataset
ChIP WA01 GSE94322.DUX4.WA01 239 bp overlap
Dux 1 dataset
Motif DE_72h DE_72h-Dux_MA0611.3 11 bp overlap
ELF1 1 dataset
ChIP Hep-G2 ENCSR321VGW.ELF1.Hep-G2 136 bp overlap
ERG 1 dataset
ChIP TSU-1621MT_ATRA GSE60477.ERG.TSU-1621MT_ATRA 194 bp overlap
EWSR1-FLI1 1 dataset
Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap
EZH2 2 datasets
ChIP SU-DHL-6 GSE134136.EZH2.SU-DHL-6 317 bp overlap
ChIP neural progenitor cell ENCFF018MKA 357 bp overlap
EZH2_phosphoT487 2 datasets
ChIP PC-9 ENCSR702GMW.EZH2_phosphoT487.PC-9 244 bp overlap
ChIP neural_progenitor ENCSR656MXA.EZH2_phosphoT487.neural_progenitor 310 bp overlap
FIGLA 1 dataset
Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap
FOXA1 5 datasets
ChIP MCF-7-TAMR-1_4OH-Tam GSE75201.FOXA1.MCF-7-TAMR-1_4OH-Tam 111 bp overlap
ChIP MCF-7_E2 GSE60270.FOXA1.MCF-7_E2 240 bp overlap
ChIP MCF-7_TNF GSE59530.FOXA1.MCF-7_TNF 147 bp overlap
ChIP T-47D_CR3flp GSE99479.FOXA1.T-47D_CR3flp 265 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 336 bp overlap
FOXA2 5 datasets
ChIP DE DE-FOXA2-1 149 bp overlap
ChIP DE DE-FOXA2-1 599 bp overlap
ChIP DE DE-FOXA2-2 257 bp overlap
ChIP DE DE-FOXA2-2 545 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 344 bp overlap
FOXB1 1 dataset
Motif DE_72h DE_72h-FOXB1_MA0845.1 11 bp overlap
FOXC1 1 dataset
Motif DE_72h DE_72h-FOXC1_MA0032.2 11 bp overlap
FOXC2 1 dataset
Motif DE_72h DE_72h-FOXC2_MA0846.2 11 bp overlap
FOXD3 1 dataset
Motif DE_72h DE_72h-FOXD3_MA0041.3 14 bp overlap
Foxj3 1 dataset
Motif DE_72h DE_72h-Foxj3_MA0851.2 9 bp overlap
GATA4 8 datasets
ChIP DE DE-GATA4-1 494 bp overlap
ChIP DE DE-GATA4-2 282 bp overlap
ChIP DE DE-GATA4-2 507 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 335 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 300 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 536 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 465 bp overlap
GATA6 13 datasets
ChIP DE DE-GATA6-1 396 bp overlap
ChIP DE DE-GATA6-2 262 bp overlap
ChIP DE DE-GATA6-2 579 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 437 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 387 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 293 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 473 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 377 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 453 bp overlap
ChIP foregut GSE117136.GATA6.foregut 394 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 458 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 386 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 408 bp overlap
GSC 1 dataset
Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap
GSC2 1 dataset
Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap
HAND2 3 datasets
ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 478 bp overlap
ChIP Kelly GSE94822.HAND2.Kelly 194 bp overlap
ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 473 bp overlap
HNF4A 1 dataset
Motif DE_72h DE_72h-HNF4A_MA0114.5 9 bp overlap
HNF4G 1 dataset
Motif DE_72h DE_72h-HNF4G_MA0484.3 9 bp overlap
Hand1::Tcf3 1 dataset
Motif DE_72h DE_72h-Hand1Tcf3_MA0092.2 9 bp overlap
Hoxa13 1 dataset
Motif DE_72h DE_72h-Hoxa13_MA0650.4 8 bp overlap
Hoxd13 1 dataset
Motif DE_72h DE_72h-Hoxd13_MA0909.4 7 bp overlap
ISL1 1 dataset
ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 328 bp overlap
JUN 3 datasets
ChIP DE_D1 S40-DE-d1-JUN-exp2 348 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 372 bp overlap
ChIP MDA-BoM-1833 GSE112444.JUN.MDA-BoM-1833 232 bp overlap
KDM1A 3 datasets
ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 523 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 560 bp overlap
ChIP pancreatic-progenitor_PP2-KDM1A-inh GSE104840.KDM1A.pancreatic-progenitor_PP2-KDM1A-inh 376 bp overlap
KLF12 1 dataset
Motif DE_72h DE_72h-KLF12_MA0742.2 9 bp overlap
KLF14 1 dataset
Motif DE_72h DE_72h-KLF14_MA0740.2 9 bp overlap
KLF4 1 dataset
ChIP HAP1 GSE130417.KLF4.HAP1 312 bp overlap
KLF7 1 dataset
Motif DE_72h DE_72h-KLF7_MA1959.2 8 bp overlap
KLF9 1 dataset
ChIP GBM1A GSE62211.KLF9.GBM1A 95 bp overlap
MED1 1 dataset
ChIP dopaminergic-neuron_Dopamine_neurons GSE93905.MED1.dopaminergic-neuron_Dopamine_neurons 149 bp overlap
MEF2A 1 dataset
Motif DE_72h DE_72h-MEF2A_MA0052.5 10 bp overlap
MEF2C 1 dataset
Motif DE_72h DE_72h-MEF2C_MA0497.2 11 bp overlap
MEIS1 1 dataset
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MYBL2 1 dataset
ChIP A-673 GSE119971.MYBL2.A-673 237 bp overlap
MYCN 1 dataset
ChIP Kelly GSE94822.MYCN.Kelly 129 bp overlap
NCAPH2 1 dataset
ChIP IMR-90_FLAG_OIS GSE118494.NCAPH2.IMR-90_FLAG_OIS 517 bp overlap
NKX2-3 1 dataset
Motif DE_72h DE_72h-NKX2-3_MA0672.2 8 bp overlap
NKX2-4 1 dataset
Motif DE_72h DE_72h-NKX2-4_MA2003.2 8 bp overlap
NKX2-8 1 dataset
Motif DE_72h DE_72h-NKX2-8_MA0673.2 8 bp overlap
NR2C1 1 dataset
Motif DE_72h DE_72h-NR2C1_MA1535.2 6 bp overlap
NR2C2 1 dataset
Motif DE_72h DE_72h-NR2C2_MA1536.2 6 bp overlap
NRIP1 1 dataset
ChIP MCF-7 ERP005838.NRIP1.MCF-7 130 bp overlap
Nr1H2 1 dataset
Motif DE_72h DE_72h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 1 dataset
Motif DE_72h DE_72h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 1 dataset
Motif DE_72h DE_72h-Nr1h3_MA2337.1 6 bp overlap
Nr2e1 1 dataset
Motif DE_72h DE_72h-Nr2e1_MA0676.1 9 bp overlap
ONECUT1 2 datasets
Motif DE_72h DE_72h-ONECUT1_MA0679.3 9 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 361 bp overlap
ONECUT3 1 dataset
Motif DE_72h DE_72h-ONECUT3_MA0757.2 12 bp overlap
OTX1 1 dataset
Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap
PDX1 4 datasets
ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 268 bp overlap
ChIP islet ERP001456.PDX1.islet 147 bp overlap
ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 409 bp overlap
ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 632 bp overlap
PHOX2B 2 datasets
ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 270 bp overlap
ChIP SK-N-BE2-C GSE94822.PHOX2B.SK-N-BE2-C 288 bp overlap
PITX1 1 dataset
Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap
PITX2 1 dataset
Motif DE_72h DE_72h-PITX2_MA1547.2 8 bp overlap
PITX3 1 dataset
Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap
RAD21 4 datasets
ChIP HAP1 GSE126634.RAD21.HAP1 284 bp overlap
ChIP HAP1 GSE152721.RAD21.HAP1 407 bp overlap
ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 575 bp overlap
ChIP HAP1_clone25 GSE152721.RAD21.HAP1_clone25 376 bp overlap
RARA 2 datasets
ChIP hiPSC_D3 GSE109172.RARA.hiPSC_D3 244 bp overlap
ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 291 bp overlap
RBPJ 1 dataset
ChIP GSC8-11_dasatinib GSE74557.RBPJ.GSC8-11_dasatinib 240 bp overlap
RHOXF1 1 dataset
Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 152 bp overlap
SMAD2-3 5 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 527 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 317 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 419 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 327 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 318 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 342 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 337 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 288 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 241 bp overlap
SMARCA4 6 datasets
ChIP NGP GSE134626.SMARCA4.NGP 284 bp overlap
ChIP NPC_siCT GSE122631.SMARCA4.NPC_siCT 265 bp overlap
ChIP NSC GSE125033.SMARCA4.NSC 578 bp overlap
ChIP NSC GSE125033.SMARCA4.NSC 254 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 347 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 159 bp overlap
SMARCC1 1 dataset
ChIP hiPSC GSE124903.SMARCC1.hiPSC 173 bp overlap
SOX11 1 dataset
ChIP GRANT-A519 GSE52146.SOX11.GRANT-A519 90 bp overlap
SOX17 2 datasets
ChIP DE_D2 DED2-SOX17_Batch_II 318 bp overlap
ChIP DE_D2 DED2-SOX17_Batch_II 298 bp overlap
SOX17_M 2 datasets
ChIP DE_D2 DED2-SOX17-M_Batch_II 483 bp overlap
ChIP DE_D2 DED2-SOX17-M_Batch_II 360 bp overlap
SOX2 5 datasets
ChIP HNSC GSE69479.SOX2.HNSC 249 bp overlap
ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 112 bp overlap
ChIP RENVM GSE49404.SOX2.RENVM 221 bp overlap
ChIP hiPSC GSE67282.SOX2.hiPSC 202 bp overlap
ChIP hiPSC_INHI GSE67282.SOX2.hiPSC_INHI 202 bp overlap
SOX21 1 dataset
ChIP neuroepithelilal-cells GSE110505.SOX21.neuroepithelilal-cells 390 bp overlap
SOX3 1 dataset
ChIP NPC GSE122631.SOX3.NPC 210 bp overlap
SP1 2 datasets
Motif DE_72h DE_72h-SP1_MA0079.5 9 bp overlap
ChIP WA01 ENCSR000BIR.SP1.WA01 130 bp overlap
SP4 1 dataset
Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap
SP7 2 datasets
ChIP HEK293 ENCFF733RBE 483 bp overlap
ChIP HEK293 ENCSR468IJT.SP7.HEK293 245 bp overlap
SP8 1 dataset
Motif DE_72h DE_72h-SP8_MA0747.2 11 bp overlap
SP9 1 dataset
Motif DE_72h DE_72h-SP9_MA1564.2 10 bp overlap
TBX2 2 datasets
ChIP Kelly GSE94822.TBX2.Kelly 222 bp overlap
ChIP SK-N-BE2-C GSE94822.TBX2.SK-N-BE2-C 279 bp overlap
TEAD4 2 datasets
ChIP BE2C GSE84389.TEAD4.BE2C 343 bp overlap
ChIP SK-N-BE2 GSE84389.TEAD4.SK-N-BE2 343 bp overlap
TP63 1 dataset
ChIP SUIT-2 GSE115461.TP63.SUIT-2 379 bp overlap
ZEB1 1 dataset
Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap
ZNF136 1 dataset
Motif DE_72h DE_72h-ZNF136_MA1588.1 15 bp overlap
ZNF143 1 dataset
ChIP FLP143HA_T4 GSE39263.ZNF143.FLP143HA_T4 199 bp overlap
ZNF341 1 dataset
ChIP HEK293 GSE76494.ZNF341.HEK293 219 bp overlap
ZNF418 1 dataset
Motif DE_72h DE_72h-ZNF418_MA1980.1 15 bp overlap
ZNF468 1 dataset
ChIP HEK293T GSE78099.ZNF468.HEK293T 288 bp overlap
ZSCAN29 1 dataset
ChIP HEK293 GSE76494.ZSCAN29.HEK293 115 bp overlap
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