chr14 : 80,959,987 – 80,960,456
469 bp 78 TFs 1 linked gene
This 469 bp open chromatin element is linked to TSHR and is bound by 78 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
TSHR 5.0 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr14:80,954,987 – 80,965,456
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
78 transcription factors
Source
Cell type
AR 1 dataset
ChIP LNCaP_SHGATA2_R1881 GSE69043.AR.LNCaP_SHGATA2_R1881 138 bp overlap
ATF7 1 dataset
ChIP GM12878 ENCFF037PYH 92 bp overlap
Arid3a 2 datasets
Motif DE_48h DE_48h-Arid3a_MA0151.1 6 bp overlap
Motif DE_60h DE_60h-Arid3a_MA0151.1 6 bp overlap
BACH2 1 dataset
ChIP OCI-Ly7 GSE69558.BACH2.OCI-Ly7 144 bp overlap
BCL6 1 dataset
ChIP B-cell_GERMINAL_CENTER GSE68349.BCL6.B-cell_GERMINAL_CENTER 101 bp overlap
BCLAF1 1 dataset
ChIP GM12878 ENCFF306JRM 57 bp overlap
BRD4 11 datasets
ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 202 bp overlap
ChIP CLL_patient4 GSE109411.BRD4.CLL_patient4 243 bp overlap
ChIP GM15850_DMSO GSE99402.BRD4.GM15850_DMSO 216 bp overlap
ChIP Jurkat GSE83777.BRD4.Jurkat 306 bp overlap
ChIP MM1-S GSE43743.BRD4.MM1-S 469 bp overlap
ChIP MM1-S_DMSO GSE42161.BRD4.MM1-S_DMSO 274 bp overlap
ChIP MM1-S_JQ1_50NM GSE42355.BRD4.MM1-S_JQ1_50NM 151 bp overlap
ChIP MM1-S_JQ1_5NM GSE42355.BRD4.MM1-S_JQ1_5NM 440 bp overlap
ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 299 bp overlap
ChIP NCI-H2171 GSE101821.BRD4.NCI-H2171 129 bp overlap
ChIP NCI-H2171 GSE101821.BRD4.NCI-H2171 182 bp overlap
CBX5 1 dataset
ChIP GM12878 ENCFF542UDC 56 bp overlap
CDK7 1 dataset
ChIP Jurkat GSE50622.CDK7.Jurkat 314 bp overlap
CEBPA 1 dataset
ChIP T-47D_progesterone GSE132649.CEBPA.T-47D_progesterone 211 bp overlap
COMMD3-BMI1,BMI1 1 dataset
ChIP GM12878 ENCFF249AMT 114 bp overlap
CREB1 1 dataset
ChIP LNCaP-abl_SHFOXA1 GSE63034.CREB1.LNCaP-abl_SHFOXA1 223 bp overlap
CREBBP 2 datasets
ChIP tonsil_GCBC_p5 GSE89688.CREBBP.tonsil_GCBC_p5 126 bp overlap
ChIP tonsil_GCBc_p4 GSE89688.CREBBP.tonsil_GCBc_p4 174 bp overlap
DPF2 1 dataset
ChIP GM12878 ENCSR509FWH.DPF2.GM12878 70 bp overlap
EBF1 1 dataset
ChIP MUTUL GSE75503.EBF1.MUTUL 137 bp overlap
EOMES 3 datasets
Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap
Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 282 bp overlap
ETS1 1 dataset
ChIP THP-6_shCtrl GSE138516.ETS1.THP-6_shCtrl 85 bp overlap
EWSR1-FLI1 1 dataset
Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap
FOXA1 1 dataset
ChIP LNCaP_ETOH24H GSE58428.FOXA1.LNCaP_ETOH24H 111 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 423 bp overlap
ChIP DE DE-FOXA2-2 449 bp overlap
FOXO1 1 dataset
ChIP B-cell_GERMINAL_CENTER GSE68349.FOXO1.B-cell_GERMINAL_CENTER 91 bp overlap
FOXP1 2 datasets
ChIP SU-DHL-6 ERP010999.FOXP1.SU-DHL-6 195 bp overlap
ChIP U2932 ERP010999.FOXP1.U2932 298 bp overlap
GATA1::TAL1 2 datasets
Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 6 datasets
ChIP LNCaP GSE38391.GATA2.LNCaP 239 bp overlap
ChIP LNCaP GSE52725.GATA2.LNCaP 239 bp overlap
ChIP LNCaP_FBS GSE69043.GATA2.LNCaP_FBS 159 bp overlap
ChIP TF1 GSE73207.GATA2.TF1 238 bp overlap
ChIP VCaP GSE125236.GATA2.VCaP 199 bp overlap
ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 134 bp overlap
GATA3 6 datasets
ChIP Jurkat GSE76181.GATA3.Jurkat 278 bp overlap
ChIP Jurkat GSE120063.GATA3.Jurkat 308 bp overlap
ChIP Jurkat GSE68976.GATA3.Jurkat 200 bp overlap
ChIP T-47D GSE51274.GATA3.T-47D 267 bp overlap
ChIP T-47D_sc GSE122847.GATA3.T-47D_sc 233 bp overlap
ChIP thymocyte GSE71751.GATA3.thymocyte 298 bp overlap
GATA3_Nter 2 datasets
ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 296 bp overlap
ChIP T-47D_flp-ctrl GSE99479.GATA3_Nter.T-47D_flp-ctrl 216 bp overlap
GATA4 3 datasets
ChIP DE DE-GATA4-1 469 bp overlap
ChIP DE DE-GATA4-2 469 bp overlap
ChIP foregut GSE117136.GATA4.foregut 292 bp overlap
GATA5 2 datasets
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 6 datasets
ChIP DE DE-GATA6-1 405 bp overlap
ChIP DE DE-GATA6-2 469 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 368 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 419 bp overlap
Gata3 2 datasets
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HNF1A 2 datasets
Motif DE_48h DE_48h-HNF1A_MA0046.3 13 bp overlap
Motif DE_60h DE_60h-HNF1A_MA0046.3 13 bp overlap
HNF1B 2 datasets
Motif DE_48h DE_48h-HNF1B_MA0153.2 13 bp overlap
Motif DE_60h DE_60h-HNF1B_MA0153.2 13 bp overlap
Hand1::Tcf3 2 datasets
Motif DE_48h DE_48h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_60h DE_60h-Hand1Tcf3_MA0092.2 9 bp overlap
IRF2 1 dataset
Motif DE_60h DE_60h-IRF2_MA0051.2 16 bp overlap
IRF4 1 dataset
ChIP BC-3 GSE132777.IRF4.BC-3 363 bp overlap
ISL2 2 datasets
Motif DE_48h DE_48h-ISL2_MA0914.2 6 bp overlap
Motif DE_60h DE_60h-ISL2_MA0914.2 6 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 248 bp overlap
JUNB 1 dataset
ChIP GM12878 ENCSR897MMC.JUNB.GM12878 218 bp overlap
KMT2A 2 datasets
ChIP CCRF-CEM GSE83671.KMT2A.CCRF-CEM 59 bp overlap
ChIP L826 GSE83671.KMT2A.L826 93 bp overlap
MAX 3 datasets
ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 469 bp overlap
ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 288 bp overlap
ChIP P493-6 GSE42262.MAX.P493-6 227 bp overlap
MED1 3 datasets
ChIP Jurkat GSE59657.MED1.Jurkat 79 bp overlap
ChIP MM1-S_JQ1_50NM GSE49224.MED1.MM1-S_JQ1_50NM 157 bp overlap
ChIP NCI-H2171 GSE36354.MED1.NCI-H2171 469 bp overlap
MEF2B 1 dataset
ChIP tonsil GSE110682.MEF2B.tonsil 242 bp overlap
MGA::EVX1 2 datasets
Motif DE_48h DE_48h-MGAEVX1_MA1960.2 11 bp overlap
Motif DE_60h DE_60h-MGAEVX1_MA1960.2 11 bp overlap
MYB 1 dataset
ChIP Jurkat GSE59657.MYB.Jurkat 231 bp overlap
MYC 3 datasets
ChIP GP5D_SIRAD21 GSE51234.MYC.GP5D_SIRAD21 112 bp overlap
ChIP NCI-H128 GSE41105.MYC.NCI-H128 158 bp overlap
ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 469 bp overlap
NFATC3 1 dataset
Motif DE_60h DE_60h-NFATC3_MA0625.3 6 bp overlap
NFATC4 1 dataset
Motif DE_60h DE_60h-NFATC4_MA1525.3 9 bp overlap
NFIC 1 dataset
ChIP GM12878 ENCFF259FWL 145 bp overlap
NR3C1 2 datasets
ChIP MCF-7_E2_Dex GSE81510.NR3C1.MCF-7_E2_Dex 90 bp overlap
ChIP T47D-A1-2_Dex GSE112491.NR3C1.T47D-A1-2_Dex 87 bp overlap
Nfat5 1 dataset
Motif DE_60h DE_60h-Nfat5_MA0606.3 8 bp overlap
Nfatc1 1 dataset
Motif DE_60h DE_60h-Nfatc1_MA0624.3 6 bp overlap
Nfatc2 1 dataset
Motif DE_60h DE_60h-Nfatc2_MA0152.3 8 bp overlap
Nkx3-2 2 datasets
Motif DE_48h DE_48h-Nkx3-2_MA0122.4 10 bp overlap
Motif DE_60h DE_60h-Nkx3-2_MA0122.4 10 bp overlap
PGR 1 dataset
ChIP breast_tumor_Male_30 GSE104399.PGR.breast_tumor_Male_30 301 bp overlap
PML 1 dataset
ChIP GM12878 ENCFF160JQZ 172 bp overlap
PRDM1 2 datasets
Motif DE_60h DE_60h-PRDM1_MA0508.4 7 bp overlap
Motif DE_60h DE_60h-PRDM1_MA0508.4 7 bp overlap
RBPJ 1 dataset
ChIP THP-6_shCtrl GSE138516.RBPJ.THP-6_shCtrl 219 bp overlap
REL 1 dataset
ChIP Ramos GSE139810.REL.Ramos 233 bp overlap
RELB 1 dataset
ChIP GM12878 ENCFF217ADF 132 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 421 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 359 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 282 bp overlap
SMARCA4 1 dataset
ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4 201 bp overlap
SOX15 1 dataset
Motif DE_60h DE_60h-SOX15_MA1152.2 7 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 341 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 438 bp overlap
SRY 2 datasets
Motif DE_48h DE_48h-SRY_MA0084.2 7 bp overlap
Motif DE_60h DE_60h-SRY_MA0084.2 7 bp overlap
Sox6 1 dataset
Motif DE_60h DE_60h-Sox6_MA0515.1 10 bp overlap
Sox7 1 dataset
Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap
TARDBP 1 dataset
ChIP GM12878 ENCFF866POT 211 bp overlap
TBL1XR1 1 dataset
ChIP GM12878 ENCFF409FTM 144 bp overlap
TBR1 2 datasets
Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap
Motif DE_60h DE_60h-TBR1_MA0802.2 9 bp overlap
TBX2 2 datasets
Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap
Motif DE_60h DE_60h-TBX2_MA0688.2 9 bp overlap
TBX20 2 datasets
Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap
Motif DE_60h DE_60h-TBX20_MA0689.1 11 bp overlap
TBX3 2 datasets
Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap
Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap
TRPS1 2 datasets
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
ZMIZ1 2 datasets
ChIP THP-6_shCtrl GSE138516.ZMIZ1.THP-6_shCtrl 180 bp overlap
ChIP THP-6_shEts1 GSE138516.ZMIZ1.THP-6_shEts1 243 bp overlap
ZNF354A 2 datasets
Motif DE_48h DE_48h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_60h DE_60h-ZNF354A_MA1978.2 20 bp overlap
ZNF652 4 datasets
Motif DE_48h DE_48h-ZNF652_MA1657.2 9 bp overlap
Motif DE_48h DE_48h-ZNF652_MA1657.2 9 bp overlap
Motif DE_60h DE_60h-ZNF652_MA1657.2 9 bp overlap
Motif DE_60h DE_60h-ZNF652_MA1657.2 9 bp overlap
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