chr12 : 4,193,882 – 4,194,255

373 bp 84 TFs 1 linked gene

This 373 bp open chromatin element is linked to ENSG00000289105 and is bound by 84 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000289105		9.9 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

84 transcription factors

Arid3a 1 dataset

Motif DE_24h DE_24h-Arid3a_MA0151.1 6 bp overlap

BCOR 1 dataset

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 305 bp overlap

CTNNB1 1 dataset

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 183 bp overlap

DUXA 1 dataset

Motif DE_24h DE_24h-DUXA_MA0884.2 13 bp overlap

Dmbx1 1 dataset

Motif DE_24h DE_24h-Dmbx1_MA0883.2 10 bp overlap

Dux 1 dataset

Motif DE_24h DE_24h-Dux_MA0611.3 11 bp overlap

ELF2 2 datasets

Motif DE_24h DE_24h-ELF2_MA1483.3 10 bp overlap

Motif DE_72h DE_72h-ELF2_MA1483.3 10 bp overlap

ELK4 2 datasets

Motif DE_24h DE_24h-ELK4_MA0076.3 9 bp overlap

Motif DE_72h DE_72h-ELK4_MA0076.3 9 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 285 bp overlap

ESR1 2 datasets

ChIP MCF-7_estradiol-progesterone_4h GSE99626.ESR1.MCF-7_estradiol-progesterone_4h 193 bp overlap

ChIP ZR751_E2 GSE72249.ESR1.ZR751_E2 235 bp overlap

ETS1 1 dataset

ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 193 bp overlap

ETV2::HOXB13 2 datasets

Motif DE_24h DE_24h-ETV2HOXB13_MA1943.2 13 bp overlap

Motif DE_72h DE_72h-ETV2HOXB13_MA1943.2 13 bp overlap

ETV6 2 datasets

Motif DE_24h DE_24h-ETV6_MA0645.2 9 bp overlap

Motif DE_72h DE_72h-ETV6_MA0645.2 9 bp overlap

ETV7 2 datasets

Motif DE_24h DE_24h-ETV7_MA1708.2 9 bp overlap

Motif DE_72h DE_72h-ETV7_MA1708.2 9 bp overlap

EZH2 4 datasets

ChIP HeLa-S3 ENCFF318LHU 82 bp overlap

ChIP SU-DHL-6 GSE134136.EZH2.SU-DHL-6 221 bp overlap

ChIP VCaP_DHAT_2H GSE28950.EZH2.VCaP_DHAT_2H 274 bp overlap

ChIP VCaP_ETOH GSE28950.EZH2.VCaP_ETOH 255 bp overlap

FEV 2 datasets

Motif DE_24h DE_24h-FEV_MA0156.4 9 bp overlap

Motif DE_72h DE_72h-FEV_MA0156.4 9 bp overlap

FEZF1 2 datasets

ChIP HEK293 ENCFF528YED 320 bp overlap

ChIP HEK293 ENCSR827NWO.FEZF1.HEK293 218 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 371 bp overlap

ChIP DE DE-FOXA2-2 367 bp overlap

FOXD3 1 dataset

Motif DE_24h DE_24h-FOXD3_MA0041.3 14 bp overlap

GATA3 3 datasets

ChIP MCF-7 GSE122847.GATA3.MCF-7 259 bp overlap

ChIP MCF-7 GSE51274.GATA3.MCF-7 226 bp overlap

ChIP T-47D ENCSR000BMX.GATA3.T-47D 160 bp overlap

GATA3_Nter 1 dataset

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 196 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 373 bp overlap

ChIP DE DE-GATA4-2 373 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 373 bp overlap

ChIP DE DE-GATA6-2 373 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 373 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 373 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 373 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 373 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 373 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 373 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 373 bp overlap

GLIS1 1 dataset

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 89 bp overlap

Gfi1B 1 dataset

Motif DE_24h DE_24h-Gfi1B_MA0483.2 10 bp overlap

HOXA10 1 dataset

Motif DE_24h DE_24h-HOXA10_MA0899.2 9 bp overlap

HOXD9 1 dataset

Motif DE_24h DE_24h-HOXD9_MA0913.3 9 bp overlap

Isl1 1 dataset

Motif DE_24h DE_24h-Isl1_MA1608.2 7 bp overlap

JUN 5 datasets

ChIP 786-O GSE86092.JUN.786-O 165 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 334 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 373 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 327 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 373 bp overlap

KDM5B 1 dataset

ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 130 bp overlap

LHX6 1 dataset

Motif DE_24h DE_24h-LHX6_MA0658.2 8 bp overlap

MEIS1 1 dataset

Motif DE_24h DE_24h-MEIS1_MA0498.3 5 bp overlap

MTF2 1 dataset

ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 202 bp overlap

MXI1 2 datasets

Motif DE_24h DE_24h-MXI1_MA1108.3 6 bp overlap

Motif DE_72h DE_72h-MXI1_MA1108.3 6 bp overlap

MYBL2 1 dataset

Motif DE_24h DE_24h-MYBL2_MA0777.1 15 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 201 bp overlap

NKX6-3 1 dataset

Motif DE_24h DE_24h-NKX6-3_MA1530.2 8 bp overlap

NR2F2 1 dataset

ChIP MCF-7 ENCSR000BUY.NR2F2.MCF-7 192 bp overlap

Nr2e3 1 dataset

Motif DE_24h DE_24h-Nr2e3_MA0164.2 6 bp overlap

OSR2 1 dataset

Motif DE_24h DE_24h-OSR2_MA1646.2 8 bp overlap

PHOX2A 1 dataset

Motif DE_24h DE_24h-PHOX2A_MA0713.1 11 bp overlap

PHOX2B 1 dataset

Motif DE_24h DE_24h-PHOX2B_MA0681.3 12 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 307 bp overlap

PROP1 1 dataset

Motif DE_24h DE_24h-PROP1_MA0715.1 11 bp overlap

PROX1 2 datasets

Motif DE_24h DE_24h-PROX1_MA0794.1 12 bp overlap

Motif DE_72h DE_72h-PROX1_MA0794.1 12 bp overlap

Prdm15 2 datasets

Motif DE_24h DE_24h-Prdm15_MA1616.2 11 bp overlap

Motif DE_72h DE_72h-Prdm15_MA1616.2 11 bp overlap

Prdm5 2 datasets

Motif DE_24h DE_24h-Prdm5_MA1999.2 11 bp overlap

Motif DE_72h DE_72h-Prdm5_MA1999.2 11 bp overlap

RARA 3 datasets

Motif DE_24h DE_24h-RARA_MA0729.1 18 bp overlap

Motif DE_24h DE_24h-RARA_MA0730.1 17 bp overlap

Motif DE_72h DE_72h-RARA_MA0730.1 17 bp overlap

RUNX3 1 dataset

Motif DE_24h DE_24h-RUNX3_MA0684.3 8 bp overlap

Rarb 2 datasets

Motif DE_24h DE_24h-Rarb_MA0858.1 17 bp overlap

Motif DE_72h DE_72h-Rarb_MA0858.1 17 bp overlap

SATB1 1 dataset

Motif DE_24h DE_24h-SATB1_MA1963.2 7 bp overlap

SIX1 1 dataset

Motif DE_24h DE_24h-SIX1_MA1118.2 9 bp overlap

SIX2 1 dataset

Motif DE_24h DE_24h-SIX2_MA1119.2 11 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 373 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 373 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 373 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 358 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 297 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 373 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 353 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 329 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 264 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 294 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 285 bp overlap

SP5 1 dataset

Motif DE_24h DE_24h-SP5_MA1965.2 6 bp overlap

SRF 2 datasets

Motif DE_24h DE_24h-SRF_MA0083.3 16 bp overlap

Motif DE_72h DE_72h-SRF_MA0083.3 16 bp overlap

SUZ12 2 datasets

ChIP Aska-SS GSE108025.SUZ12.Aska-SS 113 bp overlap

ChIP LNCaP GSE39459.SUZ12.LNCaP 121 bp overlap

Six4 1 dataset

Motif DE_24h DE_24h-Six4_MA2001.2 7 bp overlap

Stat5b 1 dataset

Motif DE_24h DE_24h-Stat5b_MA1625.2 9 bp overlap

T 2 datasets

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 359 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 321 bp overlap

TBR1 1 dataset

Motif DE_24h DE_24h-TBR1_MA0802.2 9 bp overlap

TBX3 1 dataset

Motif DE_24h DE_24h-TBX3_MA1566.3 9 bp overlap

TEAD1 1 dataset

Motif DE_24h DE_24h-TEAD1_MA0090.4 9 bp overlap

THRB 2 datasets

Motif DE_24h DE_24h-THRB_MA1576.2 18 bp overlap

Motif DE_72h DE_72h-THRB_MA1576.2 18 bp overlap

YY1 2 datasets

ChIP H1 ENCFF524BTL 262 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 219 bp overlap

ZBTB11 2 datasets

Motif DE_24h DE_24h-ZBTB11_MA2329.1 9 bp overlap

Motif DE_72h DE_72h-ZBTB11_MA2329.1 9 bp overlap

ZBTB7A 2 datasets

Motif DE_24h DE_24h-ZBTB7A_MA0750.3 9 bp overlap

Motif DE_72h DE_72h-ZBTB7A_MA0750.3 9 bp overlap

ZFP14 2 datasets

Motif DE_24h DE_24h-ZFP14_MA1972.1 15 bp overlap

Motif DE_72h DE_72h-ZFP14_MA1972.1 15 bp overlap

ZNF317 1 dataset

Motif DE_24h DE_24h-ZNF317_MA1593.2 8 bp overlap

ZNF418 1 dataset

Motif DE_24h DE_24h-ZNF418_MA1980.1 15 bp overlap

ZNF530 1 dataset

Motif DE_24h DE_24h-ZNF530_MA1981.2 14 bp overlap

ZNF548 2 datasets

ChIP HEK293 ENCFF762PDF 324 bp overlap

ChIP HEK293 ENCSR892ZTO.ZNF548.HEK293 288 bp overlap

ZNF582 1 dataset

Motif DE_24h DE_24h-ZNF582_MA1983.2 19 bp overlap

ZNF652 2 datasets

Motif DE_24h DE_24h-ZNF652_MA1657.2 9 bp overlap

Motif DE_72h DE_72h-ZNF652_MA1657.2 9 bp overlap

ZNF667 1 dataset

Motif DE_24h DE_24h-ZNF667_MA1984.2 11 bp overlap

ZNF675 1 dataset

Motif DE_24h DE_24h-ZNF675_MA1714.2 19 bp overlap

ZNF740 1 dataset

Motif DE_24h DE_24h-ZNF740_MA0753.3 10 bp overlap

ZNF823 1 dataset

ChIP HEK293T GSE78099.ZNF823.HEK293T 290 bp overlap

ZNF85 1 dataset

Motif DE_24h DE_24h-ZNF85_MA1720.2 12 bp overlap

Znf423 2 datasets

Motif DE_24h DE_24h-Znf423_MA0116.1 15 bp overlap

Motif DE_72h DE_72h-Znf423_MA0116.1 15 bp overlap