chr8 : 64,586,989 – 64,587,617
628 bp 72 TFs 2 linked genes
This 628 bp open chromatin element is linked to BHLHE22 and BHLHE22-AS1 and is bound by 72 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
BHLHE22 6.6 kb Proximal Proximity
BHLHE22-AS1 9.6 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr8:64,581,989 – 64,592,617
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
72 transcription factors
Source
Cell type
AR 3 datasets
ChIP MCF-7 GSE48930.AR.MCF-7 420 bp overlap
ChIP MDA-MB-453_FOXA1 ERP003503.AR.MDA-MB-453_FOXA1 243 bp overlap
ChIP VCaP_DHT GSE79128.AR.VCaP_DHT 308 bp overlap
ASCL1 2 datasets
Motif DE_12h DE_12h-ASCL1_MA1100.3 8 bp overlap
Motif DE_12h DE_12h-ASCL1_MA1631.2 9 bp overlap
ASH2L 1 dataset
ChIP WA01 ENCSR850KIP.ASH2L.WA01 394 bp overlap
Ahr::Arnt 1 dataset
Motif DE_12h DE_12h-AhrArnt_MA0006.2 5 bp overlap
Ascl2 1 dataset
Motif DE_12h DE_12h-Ascl2_MA0816.1 10 bp overlap
BCL11A 1 dataset
ChIP HUDEP-2_30min GSE104676.BCL11A.HUDEP-2_30min 76 bp overlap
BCOR 3 datasets
ChIP WA01 GSE104690.BCOR.WA01 628 bp overlap
ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 162 bp overlap
ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 628 bp overlap
BHLHE22 1 dataset
Motif DE_12h DE_12h-BHLHE22_MA1635.2 6 bp overlap
BRD1 1 dataset
ChIP HUES-64 GSE104059.BRD1.HUES-64 587 bp overlap
BRD2 4 datasets
ChIP THP-1_DMSO GSE138084.BRD2.THP-1_DMSO 544 bp overlap
ChIP THP-1_iBET GSE138084.BRD2.THP-1_iBET 440 bp overlap
ChIP THP-1_iBET-BD1 GSE138084.BRD2.THP-1_iBET-BD1 466 bp overlap
ChIP THP-1_iBET-BD2 GSE138084.BRD2.THP-1_iBET-BD2 519 bp overlap
BRD3 1 dataset
ChIP THP-1_DMSO-PMA GSE138084.BRD3.THP-1_DMSO-PMA 628 bp overlap
BRD4 3 datasets
ChIP CLL_patient2_4h_CpG_BET GSE109411.BRD4.CLL_patient2_4h_CpG_BET 251 bp overlap
ChIP HEK293_Ctrl GSE129407.BRD4.HEK293_Ctrl 293 bp overlap
ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 477 bp overlap
CBFB 1 dataset
ChIP ME-1 GSE46044.CBFB.ME-1 388 bp overlap
CEBPA 1 dataset
ChIP Kasumi-1_CEBPA-ER_E2 GSE102697.CEBPA.Kasumi-1_CEBPA-ER_E2 177 bp overlap
CHD1 1 dataset
ChIP WA01 ENCSR000AQK.CHD1.WA01 236 bp overlap
CTBP2 2 datasets
ChIP H1 ENCFF329MAX 584 bp overlap
ChIP WA01 ENCSR000EUO.CTBP2.WA01 628 bp overlap
CTCF 5 datasets
ChIP T-47D_NaCl-isotonic-triptolide GSE111923.CTCF.T-47D_NaCl-isotonic-triptolide 498 bp overlap
ChIP T-47D_triptolide GSE111923.CTCF.T-47D_triptolide 338 bp overlap
ChIP THP-1_macrophage_PMA GSE96800.CTCF.THP-1_macrophage_PMA 272 bp overlap
ChIP anterior-temporal-cortex_fetal GSE116825.CTCF.anterior-temporal-cortex_fetal 163 bp overlap
ChIP hiPSC_IV8 GSE106870.CTCF.hiPSC_IV8 124 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF031ISE 542 bp overlap
E2F6 1 dataset
ChIP WA01 ENCSR000BSI.E2F6.WA01 339 bp overlap
EED 1 dataset
ChIP ProEs GSE59087.EED.ProEs 583 bp overlap
EWSR1-FLI1 1 dataset
Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap
EZH2 21 datasets
ChIP A-1847 GSE95643.EZH2.A-1847 566 bp overlap
ChIP GM23338 ENCFF613YON 628 bp overlap
ChIP GM23338 ENCFF886DXX 107 bp overlap
ChIP H1 ENCFF232NZA 628 bp overlap
ChIP LNCaP GSE39459.EZH2.LNCaP 396 bp overlap
ChIP astrocyte ENCFF365JTP 206 bp overlap
ChIP astrocyte ENCFF365JTP 209 bp overlap
ChIP endothelial_umbilical-vein ENCSR000ATA.EZH2.endothelial_umbilical-vein 391 bp overlap
ChIP endothelial_umbilical-vein ENCSR000ATA.EZH2.endothelial_umbilical-vein 139 bp overlap
ChIP epithelial_mammary ENCSR000ARE.EZH2.epithelial_mammary 358 bp overlap
ChIP hESC GSE113817.EZH2.hESC 488 bp overlap
ChIP hESC GSE13084.EZH2.hESC 271 bp overlap
ChIP hESC_KO GSE113817.EZH2.hESC_KO 147 bp overlap
ChIP hESC_KO GSE113817.EZH2.hESC_KO 113 bp overlap
ChIP hepatocyte ENCFF552DZB 628 bp overlap
ChIP keratinocyte ENCFF070STK 355 bp overlap
ChIP myotube ENCSR000ASZ.EZH2.myotube 320 bp overlap
ChIP neural cell ENCFF610EPB 401 bp overlap
ChIP neural progenitor cell ENCFF018MKA 628 bp overlap
ChIP neural progenitor cell ENCFF472NFV 628 bp overlap
ChIP prostate-cancer_plko GSE107780.EZH2.prostate-cancer_plko 438 bp overlap
EZH2_phosphoT487 1 dataset
ChIP GM23338 ENCSR591DTH.EZH2_phosphoT487.GM23338 329 bp overlap
FOXA1 2 datasets
ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 553 bp overlap
ChIP breast-cancer_heregulin-Herceptin-ICI GSE101407.FOXA1.breast-cancer_heregulin-Herceptin-ICI 523 bp overlap
GATA2 1 dataset
ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 501 bp overlap
GATA6 1 dataset
ChIP AGS GSE51936.GATA6.AGS 79 bp overlap
GCM2 1 dataset
Motif DE_12h DE_12h-GCM2_MA0767.2 8 bp overlap
GTF3C2 1 dataset
ChIP H9 GSE94418.GTF3C2.H9 362 bp overlap
HCFC1R1 1 dataset
ChIP cartilage GSE100311.HCFC1R1.cartilage 319 bp overlap
HDAC2 1 dataset
ChIP WA01 ENCSR000AVB.HDAC2.WA01 253 bp overlap
HIF1A 1 dataset
ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 191 bp overlap
IKZF1 2 datasets
ChIP GM12878 ENCFF753XDO 216 bp overlap
ChIP GM12878 ENCFF824TGK 616 bp overlap
IKZF2 1 dataset
ChIP GM12878 ENCSR680UQE.IKZF2.GM12878 269 bp overlap
JARID2 6 datasets
ChIP AMIPS6 GSE48516.JARID2.AMIPS6 542 bp overlap
ChIP AMIPS8 GSE48516.JARID2.AMIPS8 510 bp overlap
ChIP MRC-5_IPS25 GSE48516.JARID2.MRC-5_IPS25 526 bp overlap
ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 628 bp overlap
ChIP UTEIPS11 GSE48516.JARID2.UTEIPS11 607 bp overlap
ChIP UTEIPS4 GSE48516.JARID2.UTEIPS4 628 bp overlap
JUN 2 datasets
ChIP ESC S24-ESC-d0-JUN-exp1 197 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 432 bp overlap
KDM4A 2 datasets
ChIP H1 ENCFF078LED 628 bp overlap
ChIP WA01 ENCSR000AVC.KDM4A.WA01 478 bp overlap
MAX 1 dataset
ChIP H1 ENCFF914VQY 343 bp overlap
MLLT3 1 dataset
ChIP THP-1 GSE79899.MLLT3.THP-1 467 bp overlap
MXI1 1 dataset
Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap
MYC 2 datasets
ChIP CD34 GSE85488.MYC.CD34 113 bp overlap
ChIP CD34 GSE85488.MYC.CD34 113 bp overlap
MYOG 1 dataset
Motif DE_12h DE_12h-MYOG_MA0500.3 8 bp overlap
NHLH1 1 dataset
Motif DE_12h DE_12h-NHLH1_MA0048.3 9 bp overlap
NR3C1 1 dataset
ChIP A-549 ENCSR000BJR.NR3C1.A-549 110 bp overlap
Neurod2 1 dataset
Motif DE_12h DE_12h-Neurod2_MA1993.2 6 bp overlap
Olig2 1 dataset
Motif DE_12h DE_12h-Olig2_MA1997.2 6 bp overlap
PCGF2 3 datasets
ChIP NT2-D1 GSE101538.PCGF2.NT2-D1 456 bp overlap
ChIP fibroblast_MET GSE55605.PCGF2.fibroblast_MET 69 bp overlap
ChIP fibroblast_OHT GSE55605.PCGF2.fibroblast_OHT 57 bp overlap
POLR2A 2 datasets
ChIP spleen ENCFF446ZGT 135 bp overlap
ChIP spleen ENCFF706IUS 535 bp overlap
POU5F1 2 datasets
ChIP BG03 GSE21614.POU5F1.BG03 469 bp overlap
ChIP DE_D1 DED1-OCT4_Batch_II 464 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 277 bp overlap
RAD21 3 datasets
ChIP THP-1_PMA_Dex-6h GSE103477.RAD21.THP-1_PMA_Dex-6h 242 bp overlap
ChIP THP-1_PMA_IFNb-6h GSE103477.RAD21.THP-1_PMA_IFNb-6h 319 bp overlap
ChIP THP-1_Pam3csk-020m-Flavo-000m GSE103477.RAD21.THP-1_Pam3csk-020m-Flavo-000m 160 bp overlap
RBBP5 1 dataset
ChIP WA01 ENCSR000AQC.RBBP5.WA01 140 bp overlap
RELA 1 dataset
ChIP THP-1_eGFP-Pam3csk-4h GSE103477.RELA.THP-1_eGFP-Pam3csk-4h 275 bp overlap
RELB 1 dataset
ChIP GM12878 ENCSR387QUV.RELB.GM12878 286 bp overlap
RNF2 2 datasets
ChIP H1 ENCFF239FFS 410 bp overlap
ChIP SYO-1_shRING1A-B GSE139053.RNF2.SYO-1_shRING1A-B 392 bp overlap
RUNX1 3 datasets
ChIP AML_Blast GSE60130.RUNX1.AML_Blast 162 bp overlap
ChIP AML_age-50-70 GSE111821.RUNX1.AML_age-50-70 291 bp overlap
ChIP CD34 GSE64862.RUNX1.CD34 162 bp overlap
RYBP 1 dataset
ChIP WA01 GSE104690.RYBP.WA01 628 bp overlap
SIN3A 1 dataset
ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 317 bp overlap
SOX21 1 dataset
Motif DE_12h DE_12h-SOX21_MA0866.1 15 bp overlap
SUZ12 10 datasets
ChIP H1 ENCFF881NFR 628 bp overlap
ChIP LNCaP GSE39459.SUZ12.LNCaP 543 bp overlap
ChIP LNCaP-abl GSE39459.SUZ12.LNCaP-abl 407 bp overlap
ChIP NT2-D1 ENCSR000EXH.SUZ12.NT2-D1 628 bp overlap
ChIP NT2-D1 GSE101538.SUZ12.NT2-D1 442 bp overlap
ChIP NT2/D1 ENCFF574SXS 604 bp overlap
ChIP NT2/D1 ENCFF574SXS 538 bp overlap
ChIP ProEs GSE59087.SUZ12.ProEs 199 bp overlap
ChIP WA01 ENCSR000ATS.SUZ12.WA01 595 bp overlap
ChIP WA01 ENCSR000EUQ.SUZ12.WA01 461 bp overlap
TBX19 1 dataset
Motif DE_12h DE_12h-TBX19_MA0804.2 17 bp overlap
TBXT 1 dataset
Motif DE_12h DE_12h-TBXT_MA0009.2 16 bp overlap
TCF12 2 datasets
ChIP WA01 ENCSR000BIT.TCF12.WA01 193 bp overlap
ChIP WA01 ENCSR000BIT.TCF12.WA01 259 bp overlap
TFAP2C 1 dataset
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 179 bp overlap
Tcf12 1 dataset
Motif DE_12h DE_12h-Tcf12_MA0521.3 6 bp overlap
Twist2 1 dataset
Motif DE_12h DE_12h-Twist2_MA0633.3 6 bp overlap
USF2 1 dataset
ChIP K-562 GSE111469.USF2.K-562 172 bp overlap
ZBTB24 1 dataset
Motif DE_12h DE_12h-ZBTB24_MA2330.1 10 bp overlap
ZBTB48 1 dataset
ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 466 bp overlap
ZNF257 1 dataset
Motif DE_12h DE_12h-ZNF257_MA1710.2 10 bp overlap
Zfp335 1 dataset
Motif DE_12h DE_12h-Zfp335_MA2002.2 7 bp overlap
Zic1::Zic2 1 dataset
Motif DE_12h DE_12h-Zic1Zic2_MA1628.2 7 bp overlap
Zic3 1 dataset
Motif DE_12h DE_12h-Zic3_MA0697.3 7 bp overlap
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