chr8 : 41,307,746 – 41,308,094
348 bp 87 TFs 1 linked gene
This 348 bp open chromatin element is linked to SFRP1 and is bound by 87 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SFRP1 1.4 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr8:41,302,746 – 41,313,094
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
87 transcription factors
Source
Cell type
ATF2 1 dataset
ChIP WA01 ENCSR000BQU.ATF2.WA01 255 bp overlap
BCOR 1 dataset
ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 348 bp overlap
BRD1 1 dataset
ChIP HUES-64 GSE104059.BRD1.HUES-64 337 bp overlap
BRD2 1 dataset
ChIP SK-MEL-147 GSE94488.BRD2.SK-MEL-147 315 bp overlap
CBFA2T2 1 dataset
ChIP NCCIT GSE71675.CBFA2T2.NCCIT 297 bp overlap
CBX8 1 dataset
ChIP K-562 ENCSR000ATW.CBX8.K-562 338 bp overlap
CEBPD 1 dataset
Motif DE_48h DE_48h-CEBPD_MA0836.3 8 bp overlap
CHD1 3 datasets
ChIP H1 ENCFF998XEK 172 bp overlap
ChIP H1 ENCFF998XEK 301 bp overlap
ChIP H1 ENCFF998XEK 93 bp overlap
CHD7 1 dataset
ChIP WA01 ENCSR000AVA.CHD7.WA01 152 bp overlap
CTCF 4 datasets
Motif DE_12h DE_12h-CTCF_MA1929.2 31 bp overlap
Motif DE_48h DE_48h-CTCF_MA1929.2 31 bp overlap
ChIP keratinocyte GSE154221.CTCF.keratinocyte 283 bp overlap
ChIP keratinocyte ENCSR000ALJ.CTCF.keratinocyte 125 bp overlap
E2F6 1 dataset
ChIP WA01 ENCSR000BSI.E2F6.WA01 151 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 222 bp overlap
ERG 1 dataset
ChIP aortic-endothelial-cell_D16 GSE139377.ERG.aortic-endothelial-cell_D16 144 bp overlap
ETS1 1 dataset
ChIP hESC ENCSR534VHI.ETS1.hESC 126 bp overlap
EZH2 9 datasets
ChIP A673 ENCFF790MVL 348 bp overlap
ChIP A673 ENCFF955JRZ 348 bp overlap
ChIP GM23248 ENCFF404ZHM 245 bp overlap
ChIP GM23248 ENCFF506FWX 100 bp overlap
ChIP GM23338 ENCFF613YON 50 bp overlap
ChIP GM23338 ENCSR045YHA.EZH2.GM23338 156 bp overlap
ChIP Hep-G2 ENCSR000ARI.EZH2.Hep-G2 181 bp overlap
ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 198 bp overlap
ChIP SF8628 GSE94834.EZH2.SF8628 284 bp overlap
EZH2_phosphoT487 1 dataset
ChIP GM23248 ENCSR096KPA.EZH2_phosphoT487.GM23248 292 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 348 bp overlap
ChIP DE DE-FOXA2-2 348 bp overlap
FOXP1 1 dataset
ChIP H9 GSE31006.FOXP1.H9 220 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 347 bp overlap
ChIP DE DE-GATA4-2 348 bp overlap
GATA6 10 datasets
ChIP DE DE-GATA6-1 302 bp overlap
ChIP DE DE-GATA6-2 338 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 348 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 348 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 348 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 348 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 348 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 348 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 290 bp overlap
Gata3 1 dataset
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
HDAC2 2 datasets
ChIP WA01 ENCSR000AVB.HDAC2.WA01 216 bp overlap
ChIP WA01 ENCSR000BNR.HDAC2.WA01 138 bp overlap
HOXB4 1 dataset
Motif DE_48h DE_48h-HOXB4_MA1499.2 6 bp overlap
HOXC4 1 dataset
Motif DE_48h DE_48h-HOXC4_MA1504.2 6 bp overlap
HOXD3 1 dataset
Motif DE_48h DE_48h-HOXD3_MA0912.2 8 bp overlap
HOXD4 1 dataset
Motif DE_48h DE_48h-HOXD4_MA1507.2 6 bp overlap
Hmga1 1 dataset
Motif DE_48h DE_48h-Hmga1_MA2124.1 8 bp overlap
INSM1 3 datasets
Motif DE_12h DE_12h-INSM1_MA0155.1 12 bp overlap
Motif DE_24h DE_24h-INSM1_MA0155.1 12 bp overlap
Motif DE_48h DE_48h-INSM1_MA0155.1 12 bp overlap
JARID2 2 datasets
ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 237 bp overlap
ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 199 bp overlap
JUN 5 datasets
ChIP DE_D2 S02-DE-d2-JUN-exp1 314 bp overlap
ChIP ESC S24-ESC-d0-JUN-exp1 300 bp overlap
ChIP ESC S34-ESC-d0-JUN-exp2 348 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 348 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 286 bp overlap
KLF4 1 dataset
ChIP WA09 GSE105028.KLF4.WA09 290 bp overlap
Lhx1 1 dataset
Motif DE_48h DE_48h-Lhx1_MA1518.3 10 bp overlap
MAFF 1 dataset
Motif DE_12h DE_12h-MAFF_MA0495.4 11 bp overlap
MED1 1 dataset
ChIP cardiomyocyte_5 GSE85628.MED1.cardiomyocyte_5 172 bp overlap
MYCN 1 dataset
ChIP NB-1643 GSE138295.MYCN.NB-1643 80 bp overlap
Mafb 1 dataset
Motif DE_12h DE_12h-Mafb_MA0117.3 11 bp overlap
NANOG 11 datasets
ChIP GM23338 ENCFF065NZG 263 bp overlap
ChIP GM23338 ENCSR061DGF.NANOG.GM23338 239 bp overlap
ChIP H1 ENCFF747ZPQ 241 bp overlap
ChIP HUES-8 GSE109524.NANOG.HUES-8 348 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 302 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 237 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 345 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 348 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 316 bp overlap
ChIP hESC GSE20650.NANOG.hESC 205 bp overlap
ChIP hESC GSE18292.NANOG.hESC 101 bp overlap
NFATC3 3 datasets
Motif DE_12h DE_12h-NFATC3_MA0625.3 6 bp overlap
Motif DE_24h DE_24h-NFATC3_MA0625.3 6 bp overlap
Motif DE_48h DE_48h-NFATC3_MA0625.3 6 bp overlap
NIPBL 4 datasets
ChIP WA09 GSE105028.NIPBL.WA09 266 bp overlap
ChIP WA09_heat-shock GSE105028.NIPBL.WA09_heat-shock 326 bp overlap
ChIP hESC GSE64758.NIPBL.hESC 204 bp overlap
ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 202 bp overlap
Nfatc1 3 datasets
Motif DE_12h DE_12h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_24h DE_24h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_48h DE_48h-Nfatc1_MA0624.3 6 bp overlap
POLR2A 1 dataset
ChIP GM23338 ENCFF450WCS 325 bp overlap
POU1F1 1 dataset
Motif DE_48h DE_48h-POU1F1_MA0784.3 14 bp overlap
POU2F1::SOX2 1 dataset
Motif DE_48h DE_48h-POU2F1SOX2_MA1962.1 17 bp overlap
POU2F2 1 dataset
Motif DE_48h DE_48h-POU2F2_MA0507.3 13 bp overlap
POU3F2 1 dataset
Motif DE_48h DE_48h-POU3F2_MA0787.1 12 bp overlap
POU5F1 10 datasets
ChIP DE_D1 DED1-OCT4_Batch_II 348 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 348 bp overlap
ChIP NCCIT GSE36134.POU5F1.NCCIT 348 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 348 bp overlap
ChIP WA09 GSE105028.POU5F1.WA09 268 bp overlap
ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 270 bp overlap
ChIP hESC ENCSR264RJX.POU5F1.hESC 205 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 348 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 272 bp overlap
ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 259 bp overlap
POU6F1 1 dataset
Motif DE_48h DE_48h-POU6F1_MA1549.2 7 bp overlap
POU6F2 1 dataset
Motif DE_48h DE_48h-POU6F2_MA0793.2 9 bp overlap
PRDM14 4 datasets
ChIP NCCIT GSE71675.PRDM14.NCCIT 347 bp overlap
ChIP hESC GSE22767.PRDM14.hESC 348 bp overlap
ChIP hESC GSE138674.PRDM14.hESC 192 bp overlap
ChIP primordial-germ-cell-like-cell GSE138674.PRDM14.primordial-germ-cell-like-cell 348 bp overlap
Pou5f1::Sox2 1 dataset
Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap
Prdm5 2 datasets
Motif DE_24h DE_24h-Prdm5_MA1999.2 11 bp overlap
Motif DE_48h DE_48h-Prdm5_MA1999.2 11 bp overlap
RAD21 1 dataset
ChIP H1 ENCFF967OJF 228 bp overlap
RBBP5 1 dataset
ChIP WA01 ENCSR000AQC.RBBP5.WA01 145 bp overlap
REST 1 dataset
ChIP GM23338 ENCFF024TCL 265 bp overlap
RNF2 2 datasets
ChIP A-549 ENCSR798EGJ.RNF2.A-549 153 bp overlap
ChIP WA01 GSE104690.RNF2.WA01 284 bp overlap
SAP30 1 dataset
ChIP WA01 ENCSR000ATR.SAP30.WA01 180 bp overlap
SIN3A 3 datasets
ChIP H1 ENCFF042ZSL 348 bp overlap
ChIP WA01 ENCSR000EBO.SIN3A.WA01 319 bp overlap
ChIP WA01 ENCSR000BIS.SIN3A.WA01 106 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 348 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 270 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 334 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 332 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 308 bp overlap
SMAD3 2 datasets
ChIP BG03 GSE21614.SMAD3.BG03 187 bp overlap
ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 145 bp overlap
SMARCA4 2 datasets
ChIP hiPSC GSE124903.SMARCA4.hiPSC 348 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 334 bp overlap
SMARCB1 2 datasets
ChIP hiPSC GSE124903.SMARCB1.hiPSC 272 bp overlap
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 348 bp overlap
SMARCC1 2 datasets
ChIP hiPSC GSE124903.SMARCC1.hiPSC 283 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 348 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 297 bp overlap
SOX2 1 dataset
ChIP hiPSC GSE56567.SOX2.hiPSC 270 bp overlap
SP1 1 dataset
ChIP WA01 ENCSR000BIR.SP1.WA01 146 bp overlap
SP5 2 datasets
Motif DE_24h DE_24h-SP5_MA1965.2 6 bp overlap
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
SP8 3 datasets
Motif DE_12h DE_12h-SP8_MA0747.2 11 bp overlap
Motif DE_24h DE_24h-SP8_MA0747.2 11 bp overlap
Motif DE_48h DE_48h-SP8_MA0747.2 11 bp overlap
SS18-SSX 1 dataset
ChIP fibroblast_78aa-SSX-Tail GSE139053.SS18-SSX.fibroblast_78aa-SSX-Tail 348 bp overlap
SUZ12 2 datasets
ChIP NT2-D1 ENCSR000EXH.SUZ12.NT2-D1 312 bp overlap
ChIP SYO-1_shRING1A-B GSE139053.SUZ12.SYO-1_shRING1A-B 196 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 193 bp overlap
TAF1 1 dataset
ChIP WA01 ENCSR000BHO.TAF1.WA01 258 bp overlap
TAF7 1 dataset
ChIP H1 ENCFF061XZZ 210 bp overlap
TBP 5 datasets
ChIP H1 ENCFF859IIO 348 bp overlap
ChIP WA01 ENCSR000ECB.TBP.WA01 272 bp overlap
ChIP hESC GSE122298.TBP.hESC 226 bp overlap
ChIP hESC_10h GSE122298.TBP.hESC_10h 139 bp overlap
ChIP hESC_2h GSE122298.TBP.hESC_2h 138 bp overlap
TBX5 2 datasets
ChIP G296S_4 GSE85628.TBX5.G296S_4 110 bp overlap
ChIP cardiomyocyte_5 GSE85628.TBX5.cardiomyocyte_5 248 bp overlap
TFAP2C 1 dataset
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 348 bp overlap
TRPS1 1 dataset
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
ZIC1 2 datasets
Motif DE_12h DE_12h-ZIC1_MA0696.1 14 bp overlap
Motif DE_48h DE_48h-ZIC1_MA0696.1 14 bp overlap
ZIC4 2 datasets
Motif DE_12h DE_12h-ZIC4_MA0751.2 14 bp overlap
Motif DE_48h DE_48h-ZIC4_MA0751.2 14 bp overlap
ZIC5 2 datasets
Motif DE_12h DE_12h-ZIC5_MA1584.2 15 bp overlap
Motif DE_48h DE_48h-ZIC5_MA1584.2 15 bp overlap
ZNF143 1 dataset
ChIP WA09_heat-shock GSE105028.ZNF143.WA09_heat-shock 201 bp overlap
ZNF331 1 dataset
Motif DE_12h DE_12h-ZNF331_MA1726.2 10 bp overlap
ZNF460 2 datasets
Motif DE_12h DE_12h-ZNF460_MA1596.1 16 bp overlap
Motif DE_48h DE_48h-ZNF460_MA1596.1 16 bp overlap
ZNF558 1 dataset
Motif DE_48h DE_48h-ZNF558_MA2335.1 29 bp overlap
ZNF684 3 datasets
Motif DE_12h DE_12h-ZNF684_MA1600.2 14 bp overlap
Motif DE_24h DE_24h-ZNF684_MA1600.2 14 bp overlap
Motif DE_48h DE_48h-ZNF684_MA1600.2 14 bp overlap
ZNF701 5 datasets
Motif DE_12h DE_12h-ZNF701_MA1987.2 17 bp overlap
Motif DE_12h DE_12h-ZNF701_MA1987.2 17 bp overlap
Motif DE_24h DE_24h-ZNF701_MA1987.2 17 bp overlap
Motif DE_48h DE_48h-ZNF701_MA1987.2 17 bp overlap
Motif DE_48h DE_48h-ZNF701_MA1987.2 17 bp overlap
ZNF75D 3 datasets
Motif DE_12h DE_12h-ZNF75D_MA1601.2 12 bp overlap
Motif DE_24h DE_24h-ZNF75D_MA1601.2 12 bp overlap
Motif DE_48h DE_48h-ZNF75D_MA1601.2 12 bp overlap
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