chr1:148,384,953–148,386,164

chr1 : 148,384,953 – 148,386,164

1,211 bp 88 TFs 8 linked genes

This 1.2 kb open chromatin element is linked to 8 target genes and is bound by 88 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
RNU1-155P		at TSS	At TSS	Proximity
MIR6077		2.1 kb	Proximal	Proximity
RNVU1-2		2.5 kb	Proximal	Proximity
LINC01138		2.8 kb	Proximal	Proximity
ENSG00000291232		16.9 kb	Distal	Multiome
ENSG00000227733		138.6 kb	Distal	Multiome
NBPF11		233.4 kb	Distal	Multiome
NBPF9		717.9 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

88 transcription factors

ARID1B 2 datasets

ChIP K562 ENCFF938UXQ 272 bp overlap

ChIP K562 ENCFF938UXQ 392 bp overlap

ATF2 7 datasets

ChIP GM12878 ENCFF066HPG 171 bp overlap

ChIP HEK293 ENCFF194VKZ 73 bp overlap

ChIP HEK293 ENCSR217HTK.ATF2.HEK293 154 bp overlap

ChIP Hep-G2 ENCSR047BUZ.ATF2.Hep-G2 201 bp overlap

ChIP HepG2 ENCFF955VER 192 bp overlap

ChIP K-562 ENCSR869IUD.ATF2.K-562 129 bp overlap

ChIP K562 ENCFF139ZZG 120 bp overlap

ATF3 2 datasets

ChIP K-562 ENCSR028UIU.ATF3.K-562 180 bp overlap

ChIP K562 ENCFF604FPV 60 bp overlap

ATF7 3 datasets

ChIP Hep-G2 ENCSR545FXC.ATF7.Hep-G2 146 bp overlap

ChIP MCF-7 ENCFF578WKB 55 bp overlap

ChIP MCF-7 ENCSR866QPZ.ATF7.MCF-7 181 bp overlap

BHLHE22 1 dataset

Motif DE_72h DE_72h-BHLHE22_MA1635.2 6 bp overlap

CBFA2T2 1 dataset

ChIP K562 ENCFF963TXY 256 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 413 bp overlap

ChIP K562 ENCFF673OEZ 336 bp overlap

CEBPD 1 dataset

ChIP K-562 ENCSR000BVY.CEBPD.K-562 135 bp overlap

CREB1 4 datasets

ChIP Hep-G2 ENCSR112ALD.CREB1.Hep-G2 93 bp overlap

ChIP MCF-7 ENCFF341ZEM 182 bp overlap

ChIP MCF-7 ENCSR897JAS.CREB1.MCF-7 197 bp overlap

ChIP MCF-7 ENCSR620DUQ.CREB1.MCF-7 137 bp overlap

CTBP1 1 dataset

ChIP K562 ENCFF403WPG 545 bp overlap

ChIP anterior-temporal-cortex_fetal GSE116825.CTCF.anterior-temporal-cortex_fetal 168 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF274GAT 148 bp overlap

ChIP HepG2 ENCFF311TOD 471 bp overlap

ChIP K562 ENCFF006PJY 245 bp overlap

ChIP A-549 GSE122203.ELF1.A-549 142 bp overlap

EOMES 2 datasets

Motif DE_72h DE_72h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 488 bp overlap

ChIP HCT-116_A7A GSE152144.FOS.HCT-116_A7A 289 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 960 bp overlap

ChIP DE DE-FOXA2-2 1010 bp overlap

GABPA 1 dataset

ChIP K-562 ENCSR000BLO.GABPA.K-562 141 bp overlap

GATA1 8 datasets

ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 124 bp overlap

ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 217 bp overlap

ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 199 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 268 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 174 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 299 bp overlap

ChIP erythroblast ENCFF867JAR 605 bp overlap

ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 567 bp overlap

GATA2 7 datasets

ChIP K-562 ENCSR000DKA.GATA2.K-562 495 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 305 bp overlap

ChIP K-562 ENCSR000BKM.GATA2.K-562 257 bp overlap

ChIP K562 ENCFF088XQT 411 bp overlap

ChIP K562 ENCFF513FTZ 301 bp overlap

ChIP K562 ENCFF544PCK 251 bp overlap

ChIP K562 ENCFF830LLA 577 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 682 bp overlap

ChIP DE DE-GATA4-2 1108 bp overlap

GATA5 1 dataset

Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap

GATA6 11 datasets

ChIP DE DE-GATA6-1 1136 bp overlap

ChIP DE DE-GATA6-2 1188 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 326 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 441 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 395 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 686 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 271 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 413 bp overlap

ChIP foregut GSE117136.GATA6.foregut 287 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 266 bp overlap

Gata3 1 dataset

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

HDAC2 1 dataset

ChIP K562 ENCFF744ALD 421 bp overlap

HNF4A 1 dataset

ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 104 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 204 bp overlap

KLF16 1 dataset

ChIP K562 ENCFF464PIV 345 bp overlap

KMT2A 1 dataset

ChIP blood_cord GSE83671.KMT2A.blood_cord 172 bp overlap

ChIP K-562 GSE142227.LDB1.K-562 185 bp overlap

LIN54 1 dataset

ChIP HepG2 ENCFF662XDE 737 bp overlap

ChIP P493-6 GSE36354.MAX.P493-6 278 bp overlap

ChIP K562 ENCFF880VZB 341 bp overlap

ChIP MCF-7 ENCFF767RTQ 186 bp overlap

NCOR1 1 dataset

ChIP K562 ENCFF788MPU 421 bp overlap

NFIC 2 datasets

ChIP K562 ENCFF167YID 457 bp overlap

ChIP K562 ENCFF167YID 296 bp overlap

NHLH1 1 dataset

Motif DE_72h DE_72h-NHLH1_MA0048.3 9 bp overlap

NHLH2 1 dataset

Motif DE_72h DE_72h-NHLH2_MA1529.2 16 bp overlap

NR2F2 1 dataset

ChIP K-562 ENCSR000BRS.NR2F2.K-562 229 bp overlap

NR5A1 1 dataset

Motif DE_72h DE_72h-NR5A1_MA1540.3 12 bp overlap

Neurod2 1 dataset

Motif DE_72h DE_72h-Neurod2_MA1993.2 6 bp overlap

Nr5A2 1 dataset

Motif DE_72h DE_72h-Nr5A2_MA0505.3 9 bp overlap

Olig2 1 dataset

Motif DE_72h DE_72h-Olig2_MA1997.2 6 bp overlap

PAX5 2 datasets

ChIP NALM-6 GSE126300.PAX5.NALM-6 184 bp overlap

ChIP fetal_testis GSE100639.PAX5.fetal_testis 275 bp overlap

ChIP K-562 ENCSR000BQY.PML.K-562 413 bp overlap

POLR2A 9 datasets

ChIP GM12891 ENCFF127ICP 511 bp overlap

ChIP GM12891 ENCFF379FCI 501 bp overlap

ChIP GM12891 ENCFF379FCI 501 bp overlap

ChIP H1 ENCFF566JSR 234 bp overlap

ChIP H1 ENCFF833NJP 411 bp overlap

ChIP HCT116 ENCFF849NGT 517 bp overlap

ChIP K562 ENCFF262YXJ 447 bp overlap

ChIP K562 ENCFF514URW 225 bp overlap

ChIP K562 ENCFF757TUO 437 bp overlap

PRDM1 1 dataset

ChIP fetal_testis GSE100639.PRDM1.fetal_testis 171 bp overlap

Prdm14 2 datasets

Motif DE_48h DE_48h-Prdm14_MA1998.2 8 bp overlap

Motif DE_72h DE_72h-Prdm14_MA1998.2 8 bp overlap

RCOR1 1 dataset

ChIP K562 ENCFF216EEJ 297 bp overlap

ChIP BJAB_4h-activation GSE117250.RELA.BJAB_4h-activation 151 bp overlap

ChIP K-562 ENCSR000BMW.REST.K-562 94 bp overlap

ChIP K562 ENCFF653BQJ 611 bp overlap

RUNX1 1 dataset

ChIP K562 ENCFF136STE 311 bp overlap

SETDB1 4 datasets

ChIP HEK293 ENCFF676PLV 717 bp overlap

ChIP HEK293 ENCFF676PLV 717 bp overlap

ChIP HEK293 ENCSR348AGV.SETDB1.HEK293 505 bp overlap

ChIP U2OS ENCSR000EYD.SETDB1.U2OS 505 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 206 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 572 bp overlap

SMAD2_3 3 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 375 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 397 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 1081 bp overlap

SMAD5 2 datasets

ChIP K-562 ENCSR000FCD.SMAD5.K-562 580 bp overlap

ChIP K562 ENCFF941FJJ 466 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 861 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 1083 bp overlap

ChIP HNSC GSE69479.SOX2.HNSC 284 bp overlap

TAF7 4 datasets

ChIP H1 ENCFF061XZZ 337 bp overlap

ChIP K-562 ENCSR000BNM.TAF7.K-562 280 bp overlap

ChIP K562 ENCFF461SFY 331 bp overlap

ChIP WA01 ENCSR000BLU.TAF7.WA01 227 bp overlap

TAL1 10 datasets

ChIP CD34 GSE52924.TAL1.CD34 165 bp overlap

ChIP K-562 GSE107726.TAL1.K-562 349 bp overlap

ChIP K-562 ENCSR000EHB.TAL1.K-562 250 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 299 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 207 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 330 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 200 bp overlap

ChIP K562 ENCFF620GMX 259 bp overlap

ChIP K562 ENCFF661CCK 277 bp overlap

ChIP ProEs GSE59087.TAL1.ProEs 231 bp overlap

ChIP K-562 GSE55306.TBP.K-562 205 bp overlap

Motif DE_72h DE_72h-TBR1_MA0802.2 9 bp overlap

Motif DE_72h DE_72h-TBX1_MA0805.1 8 bp overlap

TBX18 1 dataset

Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap

Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_72h DE_72h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_72h DE_72h-TBX21_MA0690.3 10 bp overlap

Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap

TCF12 3 datasets

ChIP K-562 ENCSR744WOO.TCF12.K-562 272 bp overlap

ChIP K562 ENCFF909RDY 397 bp overlap

ChIP K562 ENCFF931DJY 275 bp overlap

ChIP K562 ENCFF319QZT 381 bp overlap

TEAD4 1 dataset

ChIP K562 ENCFF673NIK 183 bp overlap

ChIP keratinocyte GSE33571.TP63.keratinocyte 134 bp overlap

TRIM24 2 datasets

ChIP K562 ENCFF284DKY 381 bp overlap

ChIP K562 ENCFF616RIL 451 bp overlap

TRIM28 2 datasets

ChIP HEK293 ENCFF582MWI 671 bp overlap

ChIP HEK293 ENCFF582MWI 671 bp overlap

TRPS1 1 dataset

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

Motif DE_72h DE_72h-Tbx6_MA1567.3 9 bp overlap

Tcf12 1 dataset

Motif DE_72h DE_72h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif DE_72h DE_72h-Twist2_MA0633.3 6 bp overlap

ZMIZ1 1 dataset

ChIP K-562 ENCSR000EFQ.ZMIZ1.K-562 124 bp overlap

ZNF189 1 dataset

Motif DE_72h DE_72h-ZNF189_MA1725.2 9 bp overlap

ZNF320 1 dataset

ChIP HEK293 GSE76494.ZNF320.HEK293 184 bp overlap

ZNF341 1 dataset

Motif DE_72h DE_72h-ZNF341_MA1655.2 8 bp overlap

ZNF530 1 dataset

Motif DE_48h DE_48h-ZNF530_MA1981.2 14 bp overlap

ZNF639 1 dataset

ChIP K562 ENCFF271FQR 713 bp overlap

ZNF75A 2 datasets

Motif DE_48h DE_48h-ZNF75A_MA2097.1 12 bp overlap

Motif DE_72h DE_72h-ZNF75A_MA2097.1 12 bp overlap